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Amidox-M Tablet is used to treat neuropathic pain (nerve pain). It works by lowering the pain signals to the brain and promoting the synthesis of myelin, a substance that protects nerve fibres and rejuvenates injured nerve cells. In some cases, this medicine may cause side effects such as constipation, dizziness, dry mouth, feeling sleepy, and headache.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Systemic Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Amidox-M Tablet

Amidox-M Tablet is a prescription oral medicine used to manage long-term nerve pain, also known as neuropathic pain. This type of discomfort often presents as burning, stabbing, or tingling sensations, commonly caused by nerve damage from diabetes, shingles, or spinal issues. By targeting the source of abnormal pain signals and supporting nerve health, Amidox-M Tablet helps bring steady relief.

To get the best results from Amidox-M Tablet , it is important to take it consistently at the same time every day, exactly as your doctor has prescribed. You can take this medicine with or without food, though taking it with a meal can help if you have a sensitive stomach. Incorporating gentle daily movement, eating a balanced diet, and staying well-hydrated can also help support your physical recovery and overall well-being.

Like many medicines, Amidox-M Tablet can cause some mild side effects as your body adjusts, such as sleepiness, dry mouth, or light dizziness. While these are common, you should contact your doctor right away if you experience serious symptoms, such as an irregular heartbeat, sudden mood changes, or severe dizziness.

Do not take this medicine if you have recently had a heart attack or are currently taking monoamine oxidase inhibitors (MAOIs). Before starting Amidox-M Tablet , it is highly important to tell your doctor if you have a history of heart problems, glaucoma, liver disease, or difficulty urinating so they can ensure this treatment is safe for you.

This medicine can interact with alcohol, sleeping pills, and certain blood pressure medications, which can cause excessive drowsiness or sudden drops in blood pressure. If you are pregnant, breastfeeding, planning a family, or are an older adult, you should talk to your doctor or pharmacist before using Amidox-M Tablet to discuss the risks and benefits.

Uses of Amidox-M Tablet

  • Diabetic Neuropathy: Amidox-M Tablet helps relieve the burning, tingling, and stabbing pain in the hands and feet caused by nerve damage from high blood sugar levels.
  • Postherpetic Neuralgia: It manages the persistent, sharp nerve pain that can linger for months or years after a shingles infection.
  • Peripheral Neuropathy: It targets general nerve damage in the extremities, helping to reduce hypersensitivity and restore normal sensation.
  • Chronic Nerve Pain: It provides ongoing management for long-standing discomfort caused by spinal compression, sciatica, or nerve injuries.

Key Benefits

Amidox-M Tablet provides effective, dual-action relief from chronic nerve discomfort. By calming overactive nerves, it significantly reduces the constant burning or stabbing sensations that can disrupt your day. Benefits may include:

  • Relieves nerve pain: Helps reduce burning, stabbing, or tingling sensations by calming overactive nerves, making daily activities more comfortable.
  • Supports nerve health: Provides vitamin B12 (methylcobalamin), which helps repair damaged nerves and supports healthy nerve function over time.
  • Improves sleep: By reducing nerve pain, especially at night, it may help you sleep better and feel more refreshed during the day.

Directions for Use

  • Amidox-M Tablet can be taken after a meal. However, avoid taking it with spicy foods.
  • It is usually taken 1-2 times a day or as prescribed by your doctor.
  • Swallow the whole Amidox-M Tablet with a glass of water.
  • Do not break, chew, or crush it.

How Amidox-M Tablet Works

Amidox-M Tablet contains Amitriptyline and Methylcobalamin. Amitriptyline helps reduce nerve pain by increasing the levels of certain natural chemicals in the brain that block pain signals. Methylcobalamin (Vitamin B12) helps repair damaged nerves and supports healthy nerve function by maintaining the protective covering around nerves. Together, they help relieve nerve pain while supporting the recovery and proper functioning of damaged nerves.
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Alcohol

Caution

It is unclear whether alcohol can be taken while using this medication. However, as a precautionary measure, it is best to avoid alcohol while taking medication.

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Pregnancy

Caution

Amidox-M Tablet is generally not recommended in pregnancy. Your doctor will only prescribe Amidox-M Tablet for your pain while you're pregnant if the benefits of taking medicine outweigh the risks.

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Breast Feeding

Caution

Amidox-M Tablet is generally not recommended in breastfeeding. Your doctor will only prescribe Amidox-M Tablet for your pain while you're breastfeeding if the benefits of taking medicine outweigh the risks.

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Driving

Caution

Amidox-M Tablet may cause side effects like Light-headedness or dizziness, affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Limited information was available for the use of Amidox-M Tablet in patients with liver impairment. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of Amidox-M Tablet in patients with Kidney impairment. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Limited information was available for the use of Amidox-M Tablet in paediatric patients. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Caution

Amidox-M Tablet should be taken with caution in patients with heart problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Amidox-M Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Amidox-M Tablet .

What if I have taken an overdose of Amidox-M Tablet

If you take more than your prescribed dose of Amidox-M Tablet , seek immediate emergency medical care. Symptoms of an overdose can include severe drowsiness, a rapid or irregular heartbeat, confusion, dilated pupils, or difficulty breathing.

Diet & Lifestyle Advise

  • Maintain a balanced diet rich in B-complex vitamins by eating lean meats, fish, eggs, whole grains, and leafy green vegetables to support nerve recovery.
  • If you have diabetes, keep your blood sugar levels under tight control, as high blood sugar can cause further nerve damage.
  • Drink plenty of water throughout the day to help manage common side effects like dry mouth and constipation.
  • Incorporate gentle, low-impact physical activities, such as walking, swimming, or stretching, to improve blood flow to your nerves.
  • Inspect your feet daily for any cuts, blisters, or skin changes, especially if you have reduced sensation or numbness.
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How Soon It Starts Working

The time required for Amidox-M Tablet to start to work: Amidox-M Tablet starts to show its action within 1 to 2 hours of administration. The time for which the effects of Amidox-M Tablet last: Amidox-M Tablet effect lasts for 24 hours.

What if you forget to take Amidox-M Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take a double dose to make up for a missed one.

Storage

• Store Amidox-M Tablet at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid driving, riding a bicycle, or operating heavy machinery until you know how Amidox-M Tablet affects you, as it can cause significant drowsiness.
  • Do not drink alcohol while taking this medicine. Alcohol can dangerously increase drowsiness, affect your coordination, and lower your blood pressure.
  • Stand up slowly from a sitting or lying position to prevent dizziness and reduce your risk of falling.
  • Inform your surgeon, dentist, or anesthesiologist that you are taking Amidox-M Tablet well before any scheduled surgery or medical procedures.
  • Consult your doctor before taking any over-the-counter pain relievers, sleep aids, or cold medicines, as they may interact with this medication.

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  • MAO Inhibitors: Do not take this medicine with, or within 14 days of stopping, monoamine oxidase inhibitors, as this can cause dangerously high blood pressure or a life-threatening reaction.
  • Sedatives and Sleep Medicines: Taking this with other brain-calming medications, such as sleeping pills, anxiety drugs, or muscle relaxants, can cause extreme drowsiness and slow breathing.
  • Blood Pressure Medications: May interact with certain blood pressure drugs, which can cause your blood pressure to drop too low when you stand up.

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  • Alcohol: Must be avoided as it severely compounds the sedative effects of this medicine, impairs coordination, and increases the risk of liver damage.
     

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Habit Forming

No

Therapeutic Class

[CENTRAL NERVOUS SYSTEM AGENTS]

FAQs

Amidox-M Tablet is used to manage neuropathic pain due to damaged nerves.
Amidox-M Tablet is a combination of two drugs: Amitriptyline and Methylcobalamin. Amitriptyline belongs to a class of medications known as tricyclic antidepressants. Antidepressants are considered to function by boosting serotonin levels in the brain, making you feel better. And also, these can alter how your nerves receive pain signals, causing pain to subside. Methylcobalamin is a vitamin B derivative that promotes myelin synthesis, a material that protects nerve fibres and rejuvenates injured nerve cells. They work together to alleviate neuropathic pain (pain from damaged nerves).
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
Do not discontinue Amidox-M Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Amidox-M Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Amidox-M Tablet ; your doctor will reduce the dose gradually.
Amidox-M Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
The common side effects of Amidox-M Tablet are nausea, vomiting, stomach pain, diarrhoea, heartburn, dry mouth, dizziness and blurred vision. If any of these side effects of persist or worsen, please consult your doctor.
Amidox-M Tablet is not recommended for use in patients who are allergic to Amidox-M Tablet , have a history of urinary retention due to enlargement of the prostate gland (benign prostatic hypertrophy), myocardial infarction (heart attack), congestive heart failure, impaired liver function or are pregnant or breastfeeding women. However, consult your doctor if you have any concerns.
Amidox-M Tablet may cause dizziness or drowsiness as a common side effect. If you experience these side effects, avoid driving or operating heavy machines until you know how this medication affects you.
Taking more than the required dose of Amidox-M Tablet leads to an overdose. Symptoms of overdose include temporary confusion, disturbed concentration, visual hallucinations, hypothermia (a dangerous drop in temperature), drowsiness, a fast heart rate, congestive heart failure, dilated pupils, convulsions, severe low blood pressure, stupor (state of unconsciousness), coma, constipation, agitation, muscle rigidity, overactive reflexes, a high fever and vomiting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention, even if there are no symptoms.
No, you should avoid alcohol while taking Amidox-M Tablet . Alcohol can increase side effects like drowsiness, dizziness, and coordination issues, and it may also increase the risk of liver damage. Talk to your doctor if you have concerns.
Yes, some people may experience weight gain or an increased appetite while taking Amidox-M Tablet . Eating a balanced diet and staying physically active can help manage this. Talk to your doctor for personalized advice.
Dry mouth is a common side effect of this medicine. To help manage it, you can drink plenty of water, chew sugar-free gum, or suck on sugar-free hard candies. Talk to your doctor or pharmacist if the dryness is severe or does not go away.
Amidox-M Tablet is generally not recommended during pregnancy unless your doctor decides that the benefit outweighs the potential risk. Always talk to your doctor before starting this medicine if you are pregnant or planning to become pregnant.
Yes, drowsiness and sleepiness are common side effects, especially when you first start taking the medicine. For this reason, your doctor may suggest taking it in the evening. Avoid driving if you feel sleepy, and talk to your doctor if the sleepiness interferes with your daily activities.
If you have high blood pressure or heart problems, you must tell your doctor before starting Amidox-M Tablet . Because this medicine can affect your heart rate and blood pressure, your doctor will need to monitor you closely. Talk to your doctor to ensure this medicine is safe for you.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Plot No 218 & 219, Block A, Suryalok Complex, Abids, Hyderabad - 500001
Other Info - AMI0575
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