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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amikamac 500 mg Injection 2 ml is used to treat bacterial infections. It contains Amikacin sulphate, which works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of the bacterial cell. Thus, it helps treat bacterial infections. In some cases, you may experience certain common side effects such as irritation at the site of application, skin rash, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Synonym :

AMIKACIN

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Amikamac 500 mg Injection 2 ml

Amikamac 500 mg Injection 2 ml is used to treat bacterial infections. Bacterial infection can be defined as the proliferation/multiplication of harmful strains of bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Amikamac 500 mg Injection 2 ml works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, Amikamac 500 mg Injection 2 ml helps treat bacterial infections.

Amikamac 500 mg Injection 2 ml will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side effects, such as irritation at the site of application, skin rash, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amikamac 500 mg Injection 2 ml. Your doctor may advise you to get urine, blood, and hearing tests before and during the treatment to check for signs of side effects. Depending upon the results of these tests, your doctor may adjust the dose of Amikamac 500 mg Injection 2 ml. You are advised to be well hydrated before and during the treatment with Amikamac 500 mg Injection 2 ml.

Uses of Amikamac 500 mg Injection 2 ml

Treatment of Bacterial infections

Directions for Use

Amikamac 500 mg Injection 2 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Amikamac 500 mg Injection 2 ml belongs to the group of antibiotic medicines called aminoglycosides. Amikamac 500 mg Injection 2 ml is used to treat serious bacterial infections caused by bacteria. Amikamac 500 mg Injection 2 ml works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. This leads to the death of bacteria.

How Amikamac 500 mg Injection 2 ml Works

Amikamac 500 mg Injection 2 ml works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, Amikamac 500 mg Injection 2 ml helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Amikamac 500 mg Injection 2 ml
  • Eat nutrient-rich foods, including carrots, potatoes, fruits, vegetables, and healthy fats.
  • Stay hydrated by drinking plenty of fluids to flush out waste from the body.
  • Exercise regularly for overall wellness.
  • Avoid harmful substances, including excessive alcohol and smoking.
  • Be cautious with medications like ibuprofen, naproxen, and aspirin - consult your doctor before taking them.
  • Seek medical advice to identify and address underlying health issues.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.

What if I have taken an overdose of Amikamac 500 mg Injection 2 ml

The overdose of Amikamac 500 mg Injection 2 ml is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Amikamac 500 mg Injection 2 ml, please inform your doctor immediately.

Drug Warnings

Do not take Amikamac 500 mg Injection 2 ml if you are allergic to any of the components, antibiotics related to aminoglycosides, sulphites, if you are suffering from a disorder called myasthenia gravis (severe weakness of muscles in the body), and dehydration. Talk to your doctor before taking Amikamac 500 mg Injection 2 ml if you have any kidney problems, or hearing problems such as tinnitus (buzzing or ringing in the ears). You are advised not to drive or operate heavy machinery after taking Amikamac 500 mg Injection 2 ml as it may cause dizziness. If you are pregnant or breastfeeding, talk to your doctor before taking Amikamac 500 mg Injection 2 ml. The doctor will prescribe you Amikamac 500 mg Injection 2 ml only if the benefits outweigh the potential risks.

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
AmikacinCidofovir
Critical

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of BCG vaccine with Amikamac 500 mg Injection 2 ml can reduce its effectiveness.

How to manage the interaction:
Taking Amikamac 500 mg Injection 2 ml with the BCG vaccine can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
AmikacinCidofovir
Critical
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Co-administration of cidofovir with Amikamac 500 mg Injection 2 ml can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidofovir with Amikamac 500 mg Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
AmikacinEtacrynic acid
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of Amikamac 500 mg Injection 2 ml with Ethacrynic acid can increase the risk of developing side effects. Elderly patients, those who are dehydrated, and patients with a history of kidney problems are at greater risk.

How to manage the interaction:
Although taking Etacrynic acid and Amikamac 500 mg Injection 2 ml together can cause an interaction, it can be taken if your doctor has suggested it. Consult a doctor if you experience decreased urination, vomting, shortness of breath, blurred vision, or muscle cramps. Do not stop using any medications without a doctor's advice.
AmikacinTorasemide
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Co-administration of Amikamac 500 mg Injection 2 ml with Torasemide may increase this risk of side effects.

How to manage the interaction:
Although taking Amikamac 500 mg Injection 2 ml and torasemide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as ringing in the ears, irregular urination, vomiting, weakness, or muscle cramps. Do not discontinue any medications without consulting a doctor.
AmikacinBotulinum toxin
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of Botulinum toxin with Amikamac 500 mg Injection 2 ml may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between botulinum toxin and Amikamac 500 mg Injection 2 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness or difficulty breathing, swallowing, and speaking. Do not discontinue any medications without consulting a doctor.
AmikacinRocuronium bromide
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Co-administration of Amikamac 500 mg Injection 2 ml with rocuronium bromide enhances the effects of rocuronium bromide leading to the risk of breathing problems.

How to manage the interaction:
Taking Rocuronium bromide with Amikamac 500 mg Injection 2 ml together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, chest pain, or palpitation. Do not stop using any medications without a doctor's advice.
AmikacinTacrolimus
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of tacrolimus with Amikamac 500 mg Injection 2 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Amikamac 500 mg Injection 2 ml and tacrolimus together can result in an interaction but can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, irregular urination, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.
AmikacinAtracurium
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Co-administration of Amikamac 500 mg Injection 2 ml with Atracurium can increase the risk of developing breathing difficulties.

How to manage the interaction:
Taking Atracurium with Amikamac 500 mg Injection 2 ml together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, palpitations, chest discomfort, or dizziness. Do not discontinue any medications without consulting a doctor.
AmikacinCapreomycin
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of Amikamac 500 mg Injection 2 ml and Capreomycin can increase the risk of side effects. Elderly patients, or patients who have a history of kidney problems may be at a higher risk.

How to manage the interaction:
Although taking Amikamac 500 mg Injection 2 ml and Capreomycin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience difficulty breathing, vomiting, irregular urination, sudden weight gain or loss, swelling, muscle cramps, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AmikacinEverolimus
Severe
How does the drug interact with Amikamac 500 mg Injection 2 ml:
Coadministration of Amikamac 500 mg Injection 2 ml and Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Amikamac 500 mg Injection 2 ml and Everolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, increased or decreased urination, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food such as whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Amikamac 500 mg Injection 2 ml Substitute

Substitutes safety advice
  • Mikacin 500 mg Injection 2 ml

    by Others

    51.10per tablet
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    by AYUR

    51.10per tablet
  • Omnikacin 500 mg Injection 2 ml

    by Others

    51.10per tablet
  • Amnika-500 Injection 2 ml

    by Others

    42.75per tablet
  • AYCIN 500MG INJECTION

    by Others

    97.65per tablet
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Alcohol

Caution

You are advised not to consume alcohol while taking Amikamac 500 mg Injection 2 ml as it may lead to unwanted side-effects.

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Pregnancy

Caution

Amikamac 500 mg Injection 2 ml belongs to pregnancy category-D. If you are pregnant, the doctor will prescribe Amikamac 500 mg Injection 2 ml only if the benefits outweigh the potential risks.

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Breast Feeding

Caution

If you are breastfeeding, talk to your doctor before taking Amikamac 500 mg Injection 2 ml. The doctor will prescribe Amikamac 500 mg Injection 2 ml only if the benefits outweigh the potential risks.

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Driving

Caution

Amikamac 500 mg Injection 2 ml may cause dizziness, therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Safe if prescribed

Amikamac 500 mg Injection 2 ml is safe to be used in people with liver problems if prescribed by a doctor.

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Kidney

Caution

Amikamac 500 mg Injection 2 ml should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

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Children

Safe if prescribed

Amikamac 500 mg Injection 2 ml can be given to children if prescribed by the doctor. Dose adjustment may be required as per the age and weight of the child.

Have a query?

FAQs

Amikamac 500 mg Injection 2 ml is used to treat bacterial infections.

Amikamac 500 mg Injection 2 ml belongs to the group of antibiotic medicines called as aminoglycosides. Amikamac 500 mg Injection 2 ml is used to treat serious bacterial infections. Amikamac 500 mg Injection 2 ml works by inhibiting the production of bacterial proteins which are necessary for the existence of the bacteria. Thereby, leads to the death of bacteria.

Yes, Amikamac 500 mg Injection 2 ml may lead to changes in kidney function. Your doctor will advise you to get blood and urine tests to evaluate the levels of protein or white/red blood cells and creatinine or nitrogen in blood samples. Amikamac 500 mg Injection 2 ml should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

Yes, Amikamac 500 mg Injection 2 ml may cause dizziness. You are advised not to drive or operate heavy machinery after taking Amikamac 500 mg Injection 2 ml as it may cause dizziness and can affect vision. Drive or operate machinery only if you are alert.

Yes, antibiotics may cause diarrhoea. Include foods containing probiotics such as yoghurt, cheese, and buttermilk in your diet as it would help in proper digestion. Also, eat fibre-rich food like whole grain, beans, peas, and bananas. Consult your doctor if you have severe diarrhoea. Do not take any anti-diarrheal medicine without consulting your doctor.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - AMI0227

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