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compositionComposition:AMINOPHYLLINE-250MG
prescription
Prescription Medicine
info
AMINOPHYLLIN INJECTION 10ML

AMINOPHYLLIN INJECTION is used to treat Asthma and Chronic obstructive pulmonary disease (COPD). It contains Aminophylline, which relaxes and opens air passages in the lungs, making breathing easier. Besides this, it relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes. Common side effects of AMINOPHYLLIN INJECTION are upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMINOPHYLLINE-250MG

Manufacturer/Marketer :

Biostan India Pharmaceuticals

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About AMINOPHYLLIN INJECTION

AMINOPHYLLIN INJECTION belongs to the class of drugs called bronchodilators. It is indicated for the relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

AMINOPHYLLIN INJECTION contains Aminophylline, which helps to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, making breathing easier.

AMINOPHYLLIN INJECTION is usually administered by a qualified healthcare professional; do not self-administer. AMINOPHYLLIN INJECTION may cause certain side effects, including upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability. Most of these side effects of AMINOPHYLLIN INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before prescribing the AMINOPHYLLIN INJECTION, let your doctor know about all your medical conditions, allergic reactions, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. AMINOPHYLLIN INJECTION may cause insomnia and restlessness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Uses of AMINOPHYLLIN INJECTION

AMINOPHYLLIN INJECTION is used in the treatment of Asthma and Chronic obstructive pulmonary disease (COPD). The detailed uses of AMINOPHYLLIN INJECTION are as follows:

  • Treat acute asthma and bronchospasm: AMINOPHYLLIN INJECTION acts as a bronchodilator, relaxing the muscles in the airways and widening them to improve airflow. It is used in emergency settings to relieve sudden breathing difficulties caused by asthma, bronchitis, or emphysema.
  • Manage COPD symptoms: AMINOPHYLLIN INJECTION helps reduce airway obstruction and improve breathing in patients with chronic obstructive pulmonary disease, especially during flare-ups.

Key Benefits

AMINOPHYLLIN INJECTION contains Aminophylline. It belongs to the class of drugs called bronchodilators. It is indicated to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease. Aminophylline relaxes and opens air passages in the lungs, making breathing easier. It also relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • AMINOPHYLLIN INJECTION will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How AMINOPHYLLIN INJECTION Works

AMINOPHYLLIN INJECTION contains Aminophylline, which helps to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, making breathing easier.
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Alcohol

Caution

Alcohol may increase the levels of aminophylline in the blood, leading to serious side effects. Discuss with your doctor if you have concerns.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving AMINOPHYLLIN INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Small amounts of aminophylline are excreted in human milk. Hence, if you are breastfeeding, inform your doctor before receiving AMINOPHYLLIN INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

AMINOPHYLLIN INJECTION has no or negligible influence on the ability to drive.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving AMINOPHYLLIN INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving AMINOPHYLLIN INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kidney disease in an infant less than three months of age may affect the functioning of AMINOPHYLLIN INJECTION.

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Children

Caution

Caution should be maintained while using AMINOPHYLLIN INJECTION in infants less than three months and with kidney disease. Please consult your doctor. Your doctor may prescribe this medicine for your child if the benefits outweigh the risks.

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Heart

Caution

AMINOPHYLLIN INJECTION should be used with caution in patients with heart disease. Please consult the doctor if you have heart problems.

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Geriatrics

Caution

AMINOPHYLLIN INJECTION should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of AMINOPHYLLIN INJECTION

Since AMINOPHYLLIN INJECTION is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of AMINOPHYLLIN INJECTION may cause vomiting, hypokalemia, hyperglycemia, sinus tachycardia, seizures, and arrhythmias.

Diet & Lifestyle Advise

  • Eat a healthy diet, especially green leafy vegetables, and strictly do not consume alcohol or caffeine (coffee, tea, cola drinks, and chocolate).
  • Drink plenty of fluids daily to thin mucus, making it easier to cough out.
  • Smoking should be avoided while receiving AMINOPHYLLIN INJECTION as it can alter the blood levels of aminophylline, which may affect the dosing.
  • It is very important to maintain hygiene, like washing hands after coming from outside, as people with asthma or COPD are at a greater risk of infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

Have a query?

How Soon It Starts Working

The time required for AMINOPHYLLIN INJECTION to start to work: The time required for AMINOPHYLLIN INJECTION to show its action is unknown. The time for which the effects of AMINOPHYLLIN INJECTION last: The duration of action for AMINOPHYLLIN INJECTION is unknown.

What if you forget to take AMINOPHYLLIN INJECTION

As this medication will be administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep AMINOPHYLLIN INJECTION out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Before receiving AMINOPHYLLIN INJECTION, let your doctor know about all your medical conditions, such as if you have or have ever had seizures, heart disease, an overactive or underactive thyroid gland, high blood pressure, or kidney or liver disease or if you have a history of alcohol abuse, allergic reactions (especially aminophylline, theophylline’s, theobromine, caffeine or to any of the excipients present in AMINOPHYLLIN INJECTION), and all medication history you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before receiving AMINOPHYLLIN INJECTION. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Drug-Drug Interactions

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Drug-Drug Interactions: AMINOPHYLLIN INJECTION may interact with medicines for heartburn or an ulcer (cimetidine), antibiotics (erythromycin, ciprofloxacin), antifungal (fluconazole) medicines for gout (allopurinol, sulphinpyrazone), medicines for high blood pressure or chest pain (diltiazem, propranolol), antidepressants (fluvoxamine),  medicines for epilepsy or fits (phenytoin, carbamazepine), water pills (furosemide), medicines used heart-related medicines (isoprenaline, digoxin), anthelmintic (thiabendazole),  corticosteroids (prednisone) and oral contraceptives (ethinylestradiol), antimanic agents (lithium), anticancer drugs (interferon alfa, methotrexate), medicines used to reduce the risk of stroke (ticlopidine).

Drug-Food Interactions: AMINOPHYLLIN INJECTION may interact with alcohol. Therefore, avoid intake of alcohol with AMINOPHYLLIN INJECTION as it may increase drowsiness. St. John’s Wort (antidepressant) and caffeine-containing food or drinks should be avoided as they can affect the working of AMINOPHYLLIN INJECTION.

Drug-Disease Interactions: AMINOPHYLLIN INJECTION should be used with caution if you have heart problems, overactive thyroid gland (hyperthyroidism), stomach ulcer, liver problems, seizures (fits) or convulsions, fever, viral infection, alcoholism, male and have difficulty in passing urine (due to an enlarged prostate gland).

AminophyllineRiociguat
Critical
AminophyllineLevobunolol
Severe

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Aminophyllin Injection 10ml with Riociguat may significantly lower your blood pressure.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Riociguat can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineLevobunolol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Aminophyllin Injection 10ml with Levobunolol together could reduce the metabolism of Aminophyllin Injection 10ml and effects Levobunolol. Increased levels and enhanced effects of Aminophyllin Injection 10ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Levobunolol may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineTramadol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Tramadol with Aminophyllin Injection 10ml can increase the risk of cause seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Aminophyllin Injection 10ml and tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as seizures, dizziness, drowsiness, or difficulty concentrating, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
AminophyllinePropranolol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Aminophyllin Injection 10ml with Propranolol together can make propranolol less effective and increase the effects of Aminophyllin Injection 10ml.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Propranolol can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineCiprofloxacin
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Aminophyllin Injection 10ml with Ciprofloxacin together could increase the levels and enhance the effects of Aminophyllin Injection 10ml. Increased levels of Aminophyllin Injection 10ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Ciprofloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineTimolol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Co-administration of Aminophyllin Injection 10ml with timolol can make timolol less effective and increase the effects of Aminophyllin Injection 10ml.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Timolol can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetoprolol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Aminophyllin Injection 10ml with Metoprolol together can make metoprolol less effective and increase the effects of Aminophyllin Injection 10ml.

How to manage the interaction:
Taking Aminophyllin Injection 10ml with Metoprolol may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetrizamide
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of Metrizamide with Aminophyllin Injection 10ml can increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Co-administration of Aminophyllin Injection 10ml with Metrizamide can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AminophyllineAtenolol
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Coadministration of atenolol with Aminophyllin Injection 10ml could certainly reduce the efficacy of atenolol and enhance the effects of Aminophyllin Injection 10ml.

How to manage the interaction:
Taking atenolol alongside Aminophyllin Injection 10ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineBupropion
Severe
How does the drug interact with Aminophyllin Injection 10ml:
Bupropion is capable of causing seizures in rare cases, and combining it with Aminophyllin Injection 10ml, may enhance the risk.

How to manage the interaction:
Co-administration of bupropion along with Aminophyllin Injection 10ml can lead to interaction; it can be taken if recommended by a doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery, until you have a better understanding of how the medications impact you. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BRONCHODILATOR]

FAQs

AMINOPHYLLIN INJECTION is used to treat Asthma and Chronic obstructive pulmonary disease (COPD).
AMINOPHYLLIN INJECTION contains Aminophylline, a bronchodilator that relaxes and widens the muscles of the airways, thereby making it easier for asthma and COPD patients to breathe.
Avoid aerated drinks, fried foods, excess salts (sodium chloride or table salt), dairy products, cruciferous veggies, cold cuts, and cured meats. Also, avoid consuming high amounts of caffeine-containing tea, coffee, chocolate, and cola, as these foods already contain aminophylline, an active constituent of AMINOPHYLLIN INJECTION. Sulfites in alcoholic beverages can trigger symptoms of asthma and COPD, so avoid consuming alcoholic beverages.
No, you are not recommended to smoke while receiving AMINOPHYLLIN INJECTION as it may reduce the effectiveness of AMINOPHYLLIN INJECTION and damage your lung's airways (alveoli). Long-term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.
AMINOPHYLLIN INJECTION should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking AMINOPHYLLIN INJECTION so that the dose may be adjusted or an alternate medicine may be prescribed.
No, AMINOPHYLLIN INJECTION does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
You are not recommended to take AMINOPHYLLIN INJECTION with antibiotics such as erythromycin, tetracycline, amoxicillin, amikacin and gentamicin at the same time as it may reduce the effectiveness of antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of a minimum of 2 hours between taking AMINOPHYLLIN INJECTION and antibiotics. However, please consult a doctor before using AMINOPHYLLIN INJECTION with antibiotics or other medicines.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Mayo Clinic Staff. Drg 20073584 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Aminophylline Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Aminophylline Aminophylline. 1990. [Accessed on 01 Apr. 2019] Check here
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 01 Apr. 2019] Check here
  6. Showlabeling.Aspx. [Accessed on 02 Jun. 2026] Check here
  7. New Zealand Medicines and Medical Devices Safety Authority (Medsafe). Aminophyllineinj Consumer Medicine Information (CMI). Wellington, NZ: Medsafe; 2024. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Vaniputhur,T.N.Palayam,Gobi Taluk-Erode-638506
Other Info - AMI0043

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