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compositionComposition:AMITRIPTYLINE-12.5MG+CHLORDIAZEPOXIDE-5MG
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Prescription Medicine
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Amitias Plus Tablet is used to treat moderate to severe depression associated with moderate to severe anxiety. It contains Amitriptyline and Chlordiazepoxide, which works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Also, it helps suppress the excessive and abnormal activity of the nerve cells in the brain. In some cases, you may experience common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

AMITRIPTYLINE-12.5MG+CHLORDIAZEPOXIDE-5MG

Manufacturer/Marketer :

Matteo Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Amitias Plus Tablet

Amitias Plus Tablet is a combination oral medication prescribed to treat moderate to severe depression that occurs alongside moderate to severe anxiety. It combines two active components that work together to balance chemicals in the brain, helping to improve mood and reduce feelings of tension. This medicine is designed to address both emotional and physical symptoms of these co-occurring conditions.

For the best results, you should take Amitias Plus Tablet consistently at the same time every day, exactly as directed by your doctor. It can be taken with or without food, though taking it with food may help prevent an upset stomach. Incorporating supportive habits, such as keeping a regular sleep schedule, practising gentle physical activity, and avoiding excess caffeine, can also help maximise the benefits of this treatment.

While taking Amitias Plus Tablet , some people may experience mild side effects like drowsiness, dry mouth, or constipation. These are usually manageable, but you must contact your doctor immediately if you notice serious symptoms such as severe mood changes, confusion, difficulty urinating, or thoughts of self-harm.

Do not take this if you are recovering from a recent heart attack, have severe liver damage, or have closed-angle glaucoma. Before starting this medication, tell your doctor if you have a history of urinary blockage, thyroid problems, seizures, or a history of substance abuse, as this medicine may not be safe for you.

This medicine can interact with other substances, including alcohol, sleeping pills, and certain pain relievers, which can cause severe drowsiness or dangerously slow breathing. Smoking can also reduce how well this medicine works in your body. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor before using Amitias Plus Tablet , as special precautions or lower doses are often necessary.

Uses of Amitias Plus Tablet

Amitias Plus Tablet is used to treat moderate to severe depression that occurs alongside moderate to severe anxiety. The detailed uses of Amitias Plus Tablet are as follows:

  • Depression associated with moderate to severe anxiety: Amitias Plus Tablet helps raise mood levels while simultaneously easing persistent worry, nervousness, and physical tension.
  • Anxiety-induced sleep difficulties: By calming active brain signals, it helps patients who struggle to fall asleep or stay asleep due to racing thoughts and depression.

Key Benefits

Amitias Plus Tablet helps manage symptoms of depression and anxiety by improving mood and reducing anxiety-related symptoms. By addressing both emotional and physical symptoms, it supports better daily functioning and overall wellbeing.

  • Helps Improve Mood and Reduce Anxiety: By balancing brain chemicals involved in mood regulation, Amitias Plus Tablet helps relieve symptoms of depression while reducing feelings of anxiety, nervousness, and tension.
  • Supports Better Sleep and Relaxation: By calming the nervous system, Amitias Plus Tablet helps improve sleep quality and promotes physical relaxation, allowing you to feel more rested and refreshed.
  • Improves Daily Functioning and Quality of Life: By reducing emotional distress and supporting better sleep, Amitias Plus Tablet helps improve concentration, energy levels, and the ability to carry out everyday activities with greater confidence and comfort.

Directions for Use

  • Take Amitias Plus Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Amitias Plus Tablet Works

Amitias Plus Tablet works through the combined action of its two active components in the central nervous system. The first component, amitriptyline, is an antidepressant that increases the levels of natural chemical messengers, specifically serotonin and norepinephrine, in the brain. This action helps to correct chemical imbalances, thereby improving mood, relieving sadness, and restoring interest in daily activities. The second component, chlordiazepoxide, is a calming agent belonging to the benzodiazepine class. It enhances the effects of a natural calming chemical in the brain known as GABA. By boosting GABA activity, this component slows down excessive nerve activity, which quickly reduces feelings of panic, muscle tension, and severe anxiety. Together, these two actions provide a balanced approach to managing complex emotional symptoms.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Amitias Plus Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Unsafe

Avoid taking Amitias Plus Tablet if you are pregnant unless prescribed by a doctor as it may cause birth defects.

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Breast Feeding

Caution

Consult your doctor before taking Amitias Plus Tablet ; your doctor will decide whether Amitias Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Amitias Plus Tablet may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Amitias Plus Tablet should not be given to children as safety and effectiveness have not been established.

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Heart

Unsafe

This medicine is contraindicated in cardiac patients due to its adverse effects.

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Geriatrics

Caution

Amitias Plus Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Amitias Plus Tablet .

What if I have taken an overdose of Amitias Plus Tablet

If you suspect an overdose, seek immediate emergency medical attention. Symptoms of an overdose may include extreme drowsiness, confusion, slow reflexes, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Drink plenty of water throughout the day and eat foods high in fibre, such as whole grains, fruits, and vegetables, to help prevent constipation.
  • To ease dry mouth, suck on sugar-free hard candies, chew sugar-free gum, or take frequent sips of water.
  • Avoid drinking alcohol entirely, as it can dangerously increase the sedative effects of this medicine, causing severe drowsiness and coordination problems.
  • Stand up slowly from a sitting or lying position to give your body time to adjust, which helps prevent dizziness and accidental falls.
  • Maintain a quiet, dark, and consistent sleep environment to support the medicine's natural calming action on your sleep cycle.
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Have a query?

How Soon It Starts Working

The time required for Amitias Plus Tablet to start to work: The time required for Amitias Plus Tablet to show its action is unknown. The time for which the effects of Amitias Plus Tablet last: The duration of action for Amitias Plus Tablet is unknown.

What if you forget to take Amitias Plus Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a forgotten one.

Storage

•Store Amitias Plus Tablet tablets at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from direct light and moisture. Do not store it in bathroom cabinets.

Drug Warnings

  • Do not drive, operate machinery, or perform dangerous tasks until you know exactly how Amitias Plus Tablet affects your alertness.
  • Never stop taking this medication suddenly, as doing so can trigger uncomfortable withdrawal symptoms such as nausea, headaches, sweating, and increased anxiety; your doctor will help you by gradually increasing dose reductions when it is time to stop.
  • Avoid smoking while taking this medication, as tobacco smoke can speed up how your body processes the medicine, making it less effective.
  • Be vigilant about mental health changes, and ask a family member or close friend to help monitor your behaviour for any signs of worsening depression or suicidal thoughts, especially during the first few weeks of treatment.
  • Never share this medication with anyone else, even if they have similar symptoms, as it can be habit-forming and requires strict medical supervision.

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine within 14 days of using an MAOI antidepressant, as this can lead to high blood pressure, severe seizures, or a life-threatening chemical reaction in the brain.
  • Central Nervous System Depressants: Taking this medicine alongside opioids, sleeping pills, muscle relaxants, or strong antihistamines can cause severe drowsiness, slow breathing, and even coma.
  • Blood Pressure Medications: May alter the effectiveness of certain drugs used to manage blood pressure, requiring close monitoring by your doctor.

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verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Grapefruit can slow down how your liver processes the calming component of this medicine, increasing its levels in your blood and raising the risk of severe side effects.
     

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[PSYCHOTHERAPEUTICS]

FAQs

Amitias Plus Tablet is used to treat moderate to severe depression associated with moderate to severe anxiety.
Amitias Plus Tablet contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
Amitias Plus Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Amitias Plus Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Amitias Plus Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Amitias Plus Tablet .
Dry mouth could be a side-effect of Amitias Plus Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might occur as a side-effect of Amitias Plus Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.
Amitias Plus Tablet may cause side effects like dizziness and tiredness in some people. Consult the doctor if the condition persists or if you experience severe dizziness or tiredness.
Painkillers should be taken with Amitias Plus Tablet only if advised by the doctor. However, opioid-based analgesics should not be taken with Amitias Plus Tablet as it may cause drowsiness and breathing problems. Always check with the doctor before taking painkillers or other medicines along with Amitias Plus Tablet .
Amitias Plus Tablet may cause suicidal thoughts/behaviour; therefore, monitor the person taking Amitias Plus Tablet for any changes in mood/behaviour and report to the doctor if you notice any unusual behaviour.
Store Amitias Plus Tablet at room temperature, protected from light and moisture. Keep it out of sight and reach of children.
Yes, Amitias Plus Tablet may cause sleepiness. Do not drive or operate machinery unless you know how the medicine affects you.
Amitias Plus Tablet may cause sexual problems like decreased sexual desire, inability to reach an orgasm and erectile dysfunction in men. Discuss with the doctor if you experience sexual problems during treatment with Amitias Plus Tablet .
Amitias Plus Tablet may change the colour of urine to green or blue. It is generally harmless and resolves once the medicine is stopped. However, consult the doctor if you have any concerns regarding this.
The active ingredients of Amitias Plus Tablet are Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). It is used to treat moderate to severe depression associated with moderate to severe anxiety.
Amitias Plus Tablet can be taken with or without food as advised by the doctor. Swallow Amitias Plus Tablet as a whole with a glass of water; do not chew or crush it.
Yes, Amitias Plus Tablet is safe if taken in the dose and duration prescribed by the doctor. It should not be taken for longer durations as it may cause physical dependence.
Though Amitias Plus Tablet may help you sleep better by improving your mood, it should not be used for sleep-related issues. Talk to the doctor if you have sleep-related problems.
Amitias Plus Tablet may not be beneficial for heart health as it may cause QT prolongation (a condition that affects heart rhythm) in some people. Before starting treatment with Amitias Plus Tablet discuss you’re your doctor if you have heart rhythm problems.
Side effects of Amitias Plus Tablet include dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, you must avoid alcohol. Alcohol severely increases the sedative effects of Amitias Plus Tablet , which can lead to extreme drowsiness, breathing difficulties, and impaired coordination. Talk to your doctor if you have concerns about avoiding alcohol.
Yes. Since Amitias Plus Tablet contains Chlordiazepoxide, a benzodiazepine, prolonged or inappropriate use may lead to physical and psychological dependence. Take it only as prescribed by your doctor and do not stop it suddenly without medical advice.
Consult your doctor before taking Amitias Plus Tablet if you are pregnant, planning to become pregnant, or breastfeeding. Amitriptyline and Chlordiazepoxide may not be suitable during pregnancy or breastfeeding, as they can affect the baby. Your doctor will weigh the benefits and potential risks before recommending treatment.
Drowsiness is common, especially when starting the medicine. Your doctor may suggest taking your dose at bedtime to help manage daytime sleepiness. Talk to your doctor before changing your schedule.
Some patients may experience changes in appetite or metabolic changes that lead to weight gain. Maintaining a balanced diet and regular exercise can help manage this. Talk to your doctor if you notice sudden weight changes.
Yes. Amitias Plus Tablet can interact with several over-the-counter medicines, particularly antihistamines, sleep aids, cough and cold medicines, and other products that cause drowsiness. These combinations may increase dizziness, sleepiness, and other side effects. Always check with your doctor or pharmacist before taking any new over-the-counter medicine.

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Country of origin

India

Manufacturer/Marketer address

101-104 GCP Business centre opp. Memnagar fire station Vijay cross road Memnagar , Ahmedabad-380014 India.
Other Info - AMI0493

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