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compositionComposition:AMOXYCILLIN-400MG/5ML+CLAVULANIC ACID-57MG/5ML
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Prescription Medicine
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Amoclave DS Syrup is used to treat bacterial infections, including ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joint and bone infections. It works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXYCILLIN-400MG/5ML+CLAVULANIC ACID-57MG/5ML

Manufacturer/Marketer :

Marc Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Amoclave DS Syrup

Amoclave DS Syrup is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

Amoclave DS Syrup consists of Amoxycillin and Clavulanic acid. This medicine works by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). As a result, it helps treat infection and reduce the further spread of infection. Amoclave DS Syrup does not work against infections caused by viruses, including colds and flu.

Not everyone who is taking Amoclave DS Syrup will get these side effects. The common side effects of Amoclave DS Syrup include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

You can take Amoclave DS Syrup with food to avoid any stomach upset. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your medicine based on your medical condition. It is always important to complete your treatment course for better results.

Before starting Amoclave DS Syrup, please inform your doctor if you have any allergy (against any antibiotic) or any other components. Do not take Amoclave DS Syrup on your own as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Amoclave DS Syrup is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor if you are pregnant or breadfeeding before taking Amoclave DS Syrup.

Uses of Amoclave DS Syrup

Amoclave DS Syrup is used to treat Bacterial Infections. The detailed uses of Amoclave DS Syrup are as follows:

  • Bacterial Infections: Amoclave DS Syrup helps treat bacterial illnesses, including pneumonia and bronchitis. The composition of Amoclave DS Syrup improves efficacy against resistant microorganisms.
  • Sinusitis: Amoclave DS Syrup treats bacterial sinus infections by lowering inflammation and cleaning them.
  • Urinary Tract Infections (UTIs): Amoclave DS Syrup treats urinary tract infections caused by susceptible bacteria and provides broad-spectrum protection.
  • Skin and Soft Tissue Infection: Amoclave DS Syrup is also prescribed for treating skin and soft tissue infections, such as cellulitis and bite wounds, by its antibacterial effects to speed up the healing process.
  • Otitis Media: Amoclave DS Syrup helps to treat middle ear infections.
  • Pneumonia: Amoclave DS Syrup is also involved in treating pneumonia by efficiently fighting against the microorganisms that cause the condition.

Key Benefits

  • Amoclave DS Syrup is a broad-spectrum antibiotic that covers a very wide range of bacterial infections.
  • Amoclave DS Syrup has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy.
  • Amoclave DS Syrup helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase.
  • Amoclave DS Syrup is an effective medicine used in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.

Directions for Use

  • Amoclave DS Syrup can be taken with food to avoid stomach upset.
  • It is usually taken every 8-12 hours or as prescribed by your doctor.
  • Swallow Amoclave DS Syrup as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Amoclave DS Syrup Works

Amoclave DS Syrup consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. Amoclave DS Syrup does not work against infections caused by viruses, including colds and flu.
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Alcohol

Caution

Avoid consumption of alcohol during the treatment with Amoclave DS Syrup as it may worsen the side effects like dizziness.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking Amoclave DS Syrup. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

This medication passes into breast milk. If you are a nursing mother, consult your doctor before taking Amoclave DS Syrup. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Amoclave DS Syrup may cause dizziness in some people, so it may affect your ability to drive. Avoid driving or operating machines until you are alert after taking Amoclave DS Syrup.

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Liver

Caution

Amoclave DS Syrup to be taken with caution if you have a history of liver conditions. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Amoclave DS Syrup to be taken with caution, especially if you have a history of kidney conditions. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult the doctor. Your child's doctor will decide the dosage of this medicine depending on the weight and the severity of the infection.

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Heart

Consult your doctor

Limited information is available. Please consult your doctor.

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Geriatrics

Caution

The use of Amoclave DS Syrup in elderly patients may increase the risk of serious side effects.

What if I have taken an overdose of Amoclave DS Syrup

Take Amoclave DS Syrup only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms may include nausea, vomiting, diarrhoea, stomach pain, drowsiness, skin rash, hyperactivity, and decreased urination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.
  • Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Probiotics should be taken after taking a full course of Amoclave DS Syrup in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Avoid alcoholic beverages with Amoclave DS Syrup as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Amoclave DS Syrup in fighting off infections.
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How Soon It Starts Working

The time required for Amoclave DS Syrup to start to work: Amoclave DS Syrup starts to show its action within 1 to 2 hours of administration. The time for which the effects of Amoclave DS Syrup last: Amoclave DS Syrup effect lasts for 8 to 12 hours.

What if you forget to take Amoclave DS Syrup

If you miss a dose of Amoclave DS Syrup, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Amoclave DS Syrup out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Amoclave DS Syrup if you have an allergy to Amoclave DS Syrup, penicillin or cephalosporin class of antibiotics. Also, if you experience any allergic symptoms, including rash, swelling of the face/lips/throat, difficulty breathing, or chest tightness after taking $ name, immediately contact your doctor. 
  • People with liver diseases or jaundice (yellowing of skin/eyes) should not take Amoclave DS Syrup, as it can severely affect the liver. Inform your doctor if you have any kidney or heart disease before taking Amoclave DS Syrup.
  • The dose of Amoclave DS Syrup can vary depending on your condition and the severity of the infection. 
  • Additionally, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

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Drug-Drug Interaction: Caution should be exercised when Amoclave DS Syrup is administered in combination with gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drug (methotrexate), and drug to prevent organ transplant (mycophenolate mofetil).

Drug-Food Interaction: Avoid taking eating high-fat meals as this may make it harder for your body to absorb Amoclave DS Syrup.

Drug-Disease Interaction: People affected with liver disease (like jaundice), glandular fever (viral infection with fever and sore throat), or colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take Amoclave DS Syrup.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFECTIVES]

FAQs

Amoclave DS Syrup is used to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, and joint and bone infections.
Amoclave DS Syrup contains Amoxycillin and Clavulanic acid. Amoxycillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxycillin against the bacteria. Together, Amoclave DS Syrup helps in treating bacterial infections.
Amoclave DS Syrup is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects, please take Amoclave DS Syrup with a meal. Also, Amoclave DS Syrup should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Generally, the penicillin group of antibiotics is not advised to be taken with methotrexate, which is used for conditions like psoriasis, rheumatoid arthritis, etc. They may cause unpleasant side effects when taken together. However, Amoclave DS Syrup is relatively safer to take with methotrexate, but only if prescribed by the doctor. It is best to discuss with your doctor about using the two medicines together, who may weigh the pros and cons and decide what is best for you.
Usually, Amoclave DS Syrup does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking the medication for a prolonged time. Please consult your doctor immediately if you notice any yellowing of the skin/eyes.
Amoclave DS Syrup does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Amoclave DS Syrup for your condition.
Yes, after taking Amoclave DS Syrup, you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own; consult your doctor if the condition worsens.
Amoclave DS Syrup is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to Amoclave DS Syrup, you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding using Amoclave DS Syrup and your birth control pills.
Amoclave DS Syrup may show its effect 1.5 hours after taking the medicine. However, clinical improvement may be noticed after 48 hours.
Amoclave DS Syrup should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.
Amoclave DS Syrup contains amoxicillin and clavulanic acid used to treat bacterial infections of the ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joints and bones.
Yes, Amoclave DS Syrup is safe to use if prescribed by the doctor.
Amoclave DS Syrup should not be used if you are allergic to any of its components or if you had jaundice or liver problems when taking an antibiotic.
Do not exceed the recommended dose of Amoclave DS Syrup as it might cause stomach upset or convulsions. Take Amoclave DS Syrup only as advised by the doctor.
Store Amoclave DS Syrup at room temperature (below 25°C). Keep it out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your pharmacist regarding the disposal of medicines.
To treat your infection effectively, continue taking Amoclave DS Syrup for the prescribed duration even if your symptoms are relieved.
Amoclave DS Syrup may cause an allergic reaction like skin rash, vasculitis (inflammation of blood vessels), angioedema (swelling), and difficulty breathing. Consult the doctor if you experience these symptoms.
No, Amoclave DS Syrup does not cause drowsiness. Sometimes, it might cause dizziness as an uncommon side effect. Drive or operate machinery only if you are alert.
Amoclave DS Syrup should be swallowed as a whole with water. Take the medicine with a meal.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Amoclave DS Syrup.
The common side effects of Amoclave DS Syrup include vomiting, nausea, and diarrhoea. In case of any discomfort, speak with a doctor.
Amoclave DS Syrup should be taken only if prescribed by the doctor. It should not be taken by people who are allergic to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of this medicine, ever had a severe allergic reaction (skin rash or swelling of the face or throat) to any other antibiotic or liver problems/jaundice (yellowing of the skin) when taking an antibiotic.
Let the doctor know if you are taking gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drugs (methotrexate), and drugs to prevent organ transplant (mycophenolate mofetil).
Seek immediate medical attention if you have overdosed on Amoclave DS Syrup. Taking too much of Amoclave DS Syrup may cause upset stomach (nausea, vomiting or diarrhoea) or convulsions.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.9127 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Co Amoxiclav - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Augmentin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Amoxicillin/clavulanate potassium. [Accessed on 25 Jan. 2019]Check here
  5. Amoxicillin and clavulanic acid. 2017. [Accessed on 01 Feb. 2019]Check here
  6. Amoxicillin trihydrate and potassium clavulanate [EMC SmPC]. 2025. [Accessed on 02 Jul. 2025]Check here
  7. Augmentin 625 mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 7 July 2025]Check here

Country of origin

India
Other Info - AM33341
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