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compositionComposition:AMLODIPINE-5MG+ATENOLOL-50MG
prescription
Prescription Medicine
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Amsafe-AT Tablet 10's is used to treat hypertension (high blood pressure). It contains Amlodipine and Atenolol, which relax and widen the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient in pumping blood throughout the body. Also, it blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower high blood pressure, reduces the chances of a heart attack or stroke in the future. It may cause common side effects such as nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, and tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+ATENOLOL-50MG

Manufacturer/Marketer :

Medicare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Amsafe-AT Tablet 10's

Amsafe-AT Tablet 10's is a prescription medicine taken to treat high blood pressure (hypertension) and to help prevent chronic chest pain (angina). 

Lowering high blood pressure helps ease the burden on your cardiovascular system, reducing your long-term risk of experiencing a stroke or a heart attack.

To get the most benefit from Amsafe-AT Tablet 10's, you must take it consistently every single day at the same time. You can take this tablet with or without food, but keeping a regular routine is key. Making healthy daily choices, such as eating a low-salt diet and staying moderately active, works alongside your medicine to keep your heart healthy.

Most people tolerate this medicine well, though some may experience mild side effects like dizziness, tiredness, or mild swelling in the ankles. If you experience serious symptoms such as a very slow heartbeat, worsening chest pain, or severe dizziness, you must contact your healthcare provider right away.

Before you begin taking Amsafe-AT Tablet 10's, tell your doctor if you have a history of asthma, liver damage, kidney disease, or heart failure. Do not take this if you have a very slow resting heart rate, a serious heart block, or cardiogenic shock.

This medicine can interact with certain pain relievers, alcohol, and tobacco, which can either reduce how well it works or cause your blood pressure to drop too low. If you are pregnant, planning a pregnancy, breastfeeding, or are an older adult, talk to your doctor or pharmacist before starting this medication.
 

Uses of Amsafe-AT Tablet 10's

Your doctor may prescribe Amsafe-AT Tablet 10's to help manage the following cardiovascular conditions:

  • High blood pressure (hypertension): Helps lower elevated blood pressure, reducing the overall workload on your blood vessels and vital organs.
  • Chronic stable chest pain (angina): Helps prevent chest pain by improving blood flow to the heart muscle and reducing how hard it has to work.
     

Key Benefits

Amsafe-AT Tablet 10's helps control high blood pressure and certain heart conditions by relaxing blood vessels and slowing the heart rate. This combination improves blood flow, reduces the heart's workload, and provides long-term cardiovascular protection.

  • Lowers High Blood Pressure: Helps maintain healthy blood pressure levels, reducing the risk of complications caused by hypertension.
  • Relieves Chest Pain: Helps reduce the frequency and severity of angina, allowing you to perform daily activities with greater comfort.
  • Protects the Heart and Blood Vessels: Long-term blood pressure control helps reduce the risk of heart attack, stroke, and damage to the kidneys and other organs.
  • Improves Exercise Tolerance: By reducing the heart's workload and improving blood flow, it helps increase your ability to perform physical activities with less discomfort.
  • Provides Convenient Combination Therapy: Combines two effective medicines into a single tablet, making treatment simpler and supporting better adherence.
     
Side effects of Amsafe-AT Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.

Directions for Use

  • Amsafe-AT Tablet 10's can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Amsafe-AT Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Amsafe-AT Tablet 10's Works

Amsafe-AT Tablet 10's contains amlodipine and atenolol, which work together to help lower blood pressure and reduce the workload on the heart. Amlodipine is a calcium channel blocker that relaxes the muscles in the walls of blood vessels, allowing them to widen. This improves blood flow and helps lower blood pressure. Atenolol is a beta-blocker that works by blocking the effects of natural chemicals such as adrenaline on the heart. This slows the heart rate and reduces the force of each heartbeat, allowing the heart to pump more efficiently while requiring less oxygen. Together, these actions help lower blood pressure, improve blood flow, reduce strain on the heart, and provide better control of hypertension than either medicine alone.
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Alcohol

Unsafe

You are recommended not to consume alcohol and Amsafe-AT Tablet 10's to avoid unpleasant side effects like lowering blood pressure (hypotension).

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Pregnancy

Unsafe

Amsafe-AT Tablet 10's contains atenolol, which is a pregnancy category D drug. It is known to harm the baby if taken during pregnancy. So it is better to avoid intake of Amsafe-AT Tablet 10's in pregnant women in their second and third trimesters.

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Breast Feeding

Consult your doctor

Amsafe-AT Tablet 10's can pass through the breast milk and harm the baby, so it should not be taken while breastfeeding.

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Driving

Caution

Drive with caution. Amsafe-AT Tablet 10's usually causes drowsiness and affects driving ability.

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Liver

Caution

Amsafe-AT Tablet 10's to be taken with caution, especially if you have had a history of liver disease.

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Kidney

Caution

Amsafe-AT Tablet 10's to be taken with caution, especially if you have had a history of kidney disease.

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Children

Consult your doctor

Amsafe-AT Tablet 10's is not recommended for children below six years of age without a doctor's consent. The dose is to be adjusted and guided by a child specialist only for children above six years.

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Heart

Safe if prescribed

Amsafe-AT Tablet 10's is generally safe for heart patients if prescribed, but should be used under medical supervision.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Amsafe-AT Tablet 10's may increase the risk of side effects.

What if I have taken an overdose of Amsafe-AT Tablet 10's

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose can include severe dizziness, fainting, an extremely slow heart rate, or feeling cold and clammy.

Diet & Lifestyle Advise

  • Reduce salt intake: Eat a low-sodium diet to help your medicine lower your blood pressure more effectively.
  • Stand up slowly: To prevent dizziness, rise slowly from a sitting or lying position.
  • Keep active: Engage in regular, moderate cardiovascular exercise like brisk walking, but check with your doctor first.
  • Monitor your blood pressure: Keep a daily log of your blood pressure and pulse readings at home to share with your healthcare provider.
  • Limit alcohol and quit smoking: Both alcohol and tobacco can interfere with your blood pressure and worsen the side effects of this medicine.
     
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How Soon It Starts Working

  • The time required for Amsafe-AT Tablet 10's to start to work: The time required for Amsafe-AT Tablet 10's to start to work is 1 hour after administration.
  • The time for which the effects of Amsafe-AT Tablet 10's last: The effect of Amsafe-AT Tablet 10's lasts for 24 hours.

What if you forget to take Amsafe-AT Tablet 10's

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose entirely and resume your normal schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Amsafe-AT Tablet 10's at room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Do Not Stop Treatment Suddenly: Never stop taking Amsafe-AT Tablet 10's without consulting your doctor, as this may cause a sudden rise in blood pressure or worsen chest pain.
  • Monitor Your Heart Rate: Check your pulse regularly and contact your doctor if your resting heart rate becomes unusually slow or falls below the level advised by your healthcare provider.
  • Avoid Grapefruit Products: Grapefruit and grapefruit juice may increase the levels of amlodipine in your body and raise the risk of side effects.
  • Use Caution While Driving: Avoid driving or operating machinery until you know how this medicine affects you, as it may cause dizziness or drowsiness.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or anaesthesiologist that you are taking Amsafe-AT Tablet 10's before any medical, dental, or surgical procedure.
     

Drug-Drug Interactions

verifiedApollotooltip

Amsafe-AT Tablet 10's can interact with certain medicines, which may affect how it works or increase the risk of side effects. Inform your doctor if you are taking any of the following:

  • Other blood pressure medications: Combining this medicine with other blood pressure drugs can cause your blood pressure to drop too low.
  • Pain relievers (NSAIDs): Medicines like ibuprofen or naproxen can reduce the effectiveness of your blood pressure treatment.
  • Heart rhythm medications: Taking this with drugs used to treat irregular heartbeats can cause your heart rate to slow down dangerously.
     
Amlodipine + AtenololTheophylline
Severe
Amlodipine + AtenololRitodrine
Severe

Drug-Drug Interactions

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Amlodipine + AtenololTheophylline
Severe
How does the drug interact with Amsafe-AT Tablet:
Using Amlodipine and Atenolol with theophylline could increase the effects of theophylline.

How to manage the interaction:
Taking Amlodipine and Atenolol with theophylline can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
Amlodipine + AtenololRitodrine
Severe
How does the drug interact with Amsafe-AT Tablet:
Coadministration of Amlodipine and Atenolol with ritodrine may cause either medication to be less effective.

How to manage the interaction:
Although taking Amlodipine and Atenolol with ritodrine can result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
Amlodipine + AtenololCarvedilol
Severe
How does the drug interact with Amsafe-AT Tablet:
Taking Amlodipine and Atenolol with carvedilol may increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Amlodipine and Atenolol with Carvedilol can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience shortness of breath, palpitations, or chest discomfort, contact a doctor immediately. Do not stop taking any medication without checking with a doctor.
Amlodipine + AtenololBisoprolol
Severe
How does the drug interact with Amsafe-AT Tablet:
When Bisoprolol is combined with Amlodipine and Atenolol, the severity or risk of side effects may be increased.

How to manage the interaction:
Although there may be an interaction, Amlodipine and Atenolol can be taken with bisoprolol if prescribed by the doctor. Consult the prescriber if you experience any unusual side effects. Do not discontinue the medication without consulting a doctor.
Amlodipine + AtenololRifapentine
Severe
How does the drug interact with Amsafe-AT Tablet:
Coadministration of Amlodipine and Atenolol with Rifapentine may significantly reduce the blood levels of amlodipine, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Atenolol with Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Amlodipine + AtenololNebivolol
Severe
How does the drug interact with Amsafe-AT Tablet:
Coadministration of Amlodipine and Atenolol with Nebivolol may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amlodipine and Atenolol with Nebivolol can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Amlodipine + AtenololDiltiazem
Severe
How does the drug interact with Amsafe-AT Tablet:
Taking Amlodipine and Atenolol with diltiazem may lead to increased side effects.

How to manage the interaction:
Taking Amlodipine and Atenolol with diltiazem can result in an interaction, but it can be taken if a doctor has recommended it. However, consult the doctor if you experience tiredness, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest discomfort, increased or reduced heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Amlodipine + AtenololAcebutolol
Severe
How does the drug interact with Amsafe-AT Tablet:
Coadministration of Amlodipine and Atenolol with Acebutolol may both enhance blood pressure-lowering effect.

How to manage the interaction:
Taking Amlodipine and Atenolol with acebutolol can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Amlodipine + AtenololSirolimus
Severe
How does the drug interact with Amsafe-AT Tablet:
Co-administration of Amlodipine and Atenolol can make Sirolimus, which may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Amsafe-AT Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands, and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
Amlodipine + AtenololPhenytoin
Severe
How does the drug interact with Amsafe-AT Tablet:
Using Amlodipine and Atenolol with phenytoin may drastically lower amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amlodipine and Atenolol with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how Amsafe-AT Tablet 10's works or increase the risk of side effects.

  • Grapefruit and grapefruit juice: Can increase the concentration of the medication in your blood, making side effects like dizziness and ankle swelling more likely.
     
AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice while being treated with Amsafe-AT Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Amsafe-AT Tablet 10's belongs to the class of anti-hypertensive medication used to treat hypertension (high blood pressure).
Amsafe-AT Tablet 10's is a combination of anti-hypertensive medications. Amlodipine acts by relaxing and widening the constricted blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by slowing down the heart rate of the heart. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.
Yes, Amsafe-AT Tablet 10's is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
High blood pressure during pregnancy is called Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of the feet, kidney damage, and a higher risk of bleeding during pregnancy and during delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.
It is also known as fluid retention or fluid overload. Due to oedema, the affected area starts swelling up. If it does not subside, please consult your doctor immediately.
Yes, Amsafe-AT Tablet 10's can sometimes cause dizziness, so it is advised to avoid driving or operating heavy machinery while taking Amsafe-AT Tablet 10's. If you feel dizzy or lightheaded, it is recommended to rest until you feel better.
Yes, Amsafe-AT Tablet 10's is contraindicated in people with known allergies to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided for use in pregnant women who are in the second and third trimesters of their pregnancy.
The effect of this medicine can be observed within 2 to 4 hours.
Usually, treatment with Amsafe-AT Tablet 10's is long-term, even for the rest of your life. Talk to your doctor if you want to stop taking Amsafe-AT Tablet 10's.
You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking.
The most common side effects of Amsafe-AT Tablet 10's are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Amsafe-AT Tablet 10's contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker).
You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking habits.
Dizziness may also occur, especially when you get up suddenly from a lying or sitting position. If you feel dizzy, lie down so you do not faint. Then, sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away.
Amsafe-AT Tablet 10's is generally safe to take for an extended period. In fact, it works best when you take it for a long time. Consult your doctor if you experience any side effects that persist.
You can eat and drink normally while taking Amsafe-AT Tablet 10's. Eating a healthy, balanced diet can help if you have high blood pressure or another heart condition.
No, you should not stop taking this medicine even if you feel completely fine. High blood pressure often has no symptoms, and stopping the medicine suddenly can lead to a dangerous spike in blood pressure or chest pain. Talk to your doctor before making any changes.
Dizziness is common, especially when starting this medicine. Sit or lie down until the feeling passes, and try to rise slowly when standing up. If the dizziness is severe, frequent, or causes you to faint, talk to your doctor.
It is best to limit or avoid alcohol. Drinking alcohol while taking this medicine can cause your blood pressure to drop too low, which can make you feel extremely dizzy, sleepy, or lightheaded. Talk to your doctor for personalised advice.
You should avoid taking non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen regularly, as they can raise your blood pressure and reduce the effectiveness of Amsafe-AT Tablet 10's. Talk to your doctor or pharmacist about safer pain-relief options.
Grapefruit contains compounds that slow down how your body processes this medicine. This can cause the drug to build up in your body, increasing your risk of experiencing side effects like ankle swelling, headaches, and dizziness. Talk to your doctor if you have questions.
Yes, this medicine can mask the warning signs of low blood sugar, such as a fast or pounding heartbeat. You may need to monitor your blood sugar levels more closely while taking this medication. Talk to your doctor for guidance.
This medicine is generally not recommended during pregnancy or breastfeeding as it may pose risks to the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor immediately about safer alternatives.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

H.NO.1-123MYHOMEHUB8THFLOOR3RDBLOCK , HYDERABAD, Telangana, India - 500081
Other Info - AMS0032
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