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compositionComposition:LEVOFLOXACIN-250MG+ORNIDAZOLE-500MG
prescription
Prescription Medicine
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Apcin-OZ Tablet is used to treat bacterial and parasitic infections, diarrhoea and dysentery. It contains Levofloxacin and Ornidazole which work by inhibiting harmful bacteria and parasites. In some cases, this medicine may cause side effects such as nausea, loss of appetite, constipation, diarrhoea, trouble sleeping, dizziness and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LEVOFLOXACIN-250MG+ORNIDAZOLE-500MG

Manufacturer/Marketer :

Apellon Biotech

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Apcin-OZ Tablet

Apcin-OZ Tablet is an oral medicine that combines levofloxacin and ornidazole to treat a wide range of bacterial and parasitic infections. It works by eliminating the infection-causing microorganisms, helping relieve symptoms such as diarrhoea, abdominal pain, and fever while supporting a faster recovery.

To achieve the best results, you must take Apcin-OZ Tablet consistently at the exact times prescribed by your doctor. This helps maintain a steady level of the active ingredients in your system to continuously fight the infection. It is highly recommended to take this tablet with food or a meal to prevent stomach upset. Additionally, eating a bland diet and staying well-hydrated will support your body's recovery.

While taking Apcin-OZ Tablet , you might experience mild side effects like nausea, a metallic taste in your mouth, or a temporary loss of appetite. However, if you develop severe watery or bloody diarrhoea, sharp pain in your tendons, or numbness in your hands and feet, stop taking the medicine and consult your doctor immediately. These can be signs of serious complications that require urgent medical attention.

Before starting this medication, tell your doctor if you have a history of seizures, nerve damage, heart rhythm problems, or liver damage. Do not take this if you are allergic to any of the ingredients or have a history of tendon swelling or rupture caused by similar medications. It is also important to tell your healthcare provider if you are pregnant, breastfeeding, or over the age of 65, as special precautions or alternative treatments may be needed.

Uses of Apcin-OZ Tablet

Apcin-OZ Tablet is used to treat a wide range of bacterial and parasitic infections. The detailed uses of Apcin-OZ Tablet are as follows:

  • Mixed gastrointestinal infections: Apcin-OZ Tablet helps clear severe diarrhoea and dysentery caused by a combination of bacterial and parasitic organisms.
  • Gynaecological infections: It treats deep pelvic infections and reproductive tract issues by eliminating a broad spectrum of harmful microbes.
  • Severe dental abscesses: This medicine helps resolve deep gum and tooth infections where both oxygen-loving and anaerobic bacteria are present.
  • Pelvic Inflammatory Disease (PID): It stops the growth of diverse pathogens in the pelvic area, relieving pain and preventing long-term complications.

Key Benefits

This medication offers several key benefits that help you recover quickly and return to your daily routine:

  • Comprehensive Protection: By targeting two different types of disease-causing organisms simultaneously, it clears complex infections that single-action antibiotics might fail to cure.
  • Rapid Symptom Relief: It quickly halts the spread of harmful microbes, which directly reduces painful stomach cramps, frequent diarrhoea, and abdominal spasms.
  • Prevents Reoccurring Infections: The thorough action of this medicine helps ensure that all targeted pathogens are completely wiped out, lowering the chance of the infection returning or developing resistance.
Side effects of Apcin-Oz Tab
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  • Apcin-OZ Tablet should be taken after meals, to reduce the chances of stomach upset.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Apcin-OZ Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Apcin-OZ Tablet Works

To eliminate complex infections, Apcin-OZ Tablet utilises a dual-action mechanism that attacks harmful microorganisms from two different angles: The first active component in this tablet, levofloxacin, is a broad-spectrum antibiotic that targets bacteria. It works by blocking a key bacterial enzyme called DNA gyrase. Without this enzyme, bacteria cannot repair, copy, or read their genetic material. This stops them from multiplying and eventually leads to their death. The second active component, ornidazole, specifically targets anaerobic bacteria and tiny parasites (protozoa). Once inside these organisms, it is converted into an active form that directly damages their DNA. This disrupts their cellular function and prevents them from surviving. By combining these two distinct actions, Apcin-OZ Tablet effectively clears mixed infections, ensuring a comprehensive treatment that prevents the surviving germs from multiplying.
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Alcohol

Unsafe

Alcohol consumption may worsen the side effect of Apcin-OZ Tablet like dizziness. It is better to avoid alcohol while you are being treated with Apcin-OZ Tablet .

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Pregnancy

Unsafe

Apcin-OZ Tablet is not recommended for use during pregnancy since it may have harmful effects on the developing baby. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Apcin-OZ Tablet .

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Breast Feeding

Caution

Levofloxacin in Apcin-OZ Tablet is excreted into the breast milk. Please consult your doctor before taking Apcin-OZ Tablet if you are breastfeeding.

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Driving

Unsafe

Apcin-OZ Tablet may make you feel dizzy. Do not drive or operate machinery if you experience any impairment of skills, dizziness, and visual disturbances while using Apcin-OZ Tablet .

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Liver

Caution

Please take Apcin-OZ Tablet with caution and doctor's advice if you have a history of liver diseases/conditions.

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Kidney

Caution

Please take Apcin-OZ Tablet with caution and doctor's advice if you have a history of kidney diseases/conditions.

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Children

Unsafe

Apcin-OZ Tablet is not recommended for patients younger than 18 years of age.

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Heart

Caution

Apcin-OZ Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Apcin-OZ Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Apcin-OZ Tablet

If you accidentally take too much of this medicine, or if someone else swallows it, seek emergency medical care immediately. Watch for severe symptoms like extreme confusion, shaky movements, or seizures, and contact your local emergency services right away.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water and clear broths. This helps replace fluids lost from diarrhoea and assists your kidneys in safely filtering and clearing the medicine from your system.
  • Avoid Dairy Around Dosing Times: Do not consume milk, cheese, yoghurt, or calcium-fortified juices close to your dosing time. Calcium can bind with the medicine in your gut, preventing your body from absorbing it properly.
  • Minimise Sun Exposure: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing, use a broad-spectrum sunscreen, and avoid tanning beds to prevent severe sunburns.
  • Eat Bland, Soft Foods: While recovering from stomach infections, stick to simple foods like bananas, rice, applesauce, and plain toast to minimise irritation to your digestive tract.
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How Soon It Starts Working

The time required for Apcin-OZ Tablet to start to work: The effect of Apcin-OZ Tablet is observed within 1 hour of administration. The time for which the effects of Apcin-OZ Tablet last: Apcin-OZ Tablet effect lasts for 12 to 24 hours.

What if you forget to take Apcin-OZ Tablet

If you miss a dose of Apcin-OZ Tablet , take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose entirely and resume your normal schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Apcin-OZ Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep this medication in a safe place, completely out of the reach of children and pets.

Drug Warnings

  • Finish the Medication: Complete the entire prescribed course of Apcin-OZ Tablet even if you start feeling completely healthy to prevent the return of resistant bacteria.
  • Stop if Joint Pain Occurs: If you feel sudden pain, swelling, or popping in your joints, stop taking the tablet, rest, and contact your doctor immediately.
  • Do Not Drive: Avoid driving or operating machinery while taking this medicine, as it can cause dizziness, drowsiness, or coordination problems.
  • Avoid Alcohol Completely: Do not drink alcohol while taking this medicine and for at least three days after your last dose to avoid severe reactions like vomiting and rapid heart rate.
  • Separate Antacid Use: Take antacids, iron supplements, or multivitamins with zinc at least 2 hours before or 2 hours after your Apcin-OZ Tablet dose so they do not block absorption.

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids and Mineral Supplements: Products containing magnesium, aluminum, iron, or zinc can bind with the medicine in your stomach, drastically reducing how much of it is absorbed.
  • Blood Thinners (like Warfarin): This medicine can enhance the effects of blood thinners, increasing your risk of bruising or bleeding. Your doctor may need to monitor your clotting times.
  • Corticosteroids: Taking steroids alongside this medicine increases the risk of tendon swelling or tendon rupture, particularly in older adults.
  • Diabetes Medications: This medicine can alter blood sugar levels, increasing the risk of low blood sugar when combined with insulin or oral diabetes drugs.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Dairy and Calcium-Rich Foods: Foods like milk, cheese, and calcium-fortified juices can interfere with the absorption of this medicine when consumed at the same time.
  • Caffeine: This medicine may slow down how your body breaks down caffeine, leading to symptoms like jitteriness, anxiety, or sleeping difficulties.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Apcin-OZ Tablet is used to treat diarrhoea and dysentery. It also helps treat bacterial and parasitic infections.
Apcin-OZ Tablet contains Levofloxacin and Ornidazole. These drugs are antibiotics that kill and prevent the microbial growth that causes diarrhoea, dysentery and other parasitic and bacterial infections.
Please let your doctor know if you have a history of allergic reactions to medicines, liver or kidney diseases, diabetes, joint or tendon problems (tendonitis, bursitis), mood disorders (depression), myasthenia gravis (muscle weakness), blood dyscrasia (decreased peripheral blood cell counts), peripheral neuropathy (nerve damage), fits, aneurysm (weakening of an artery), blockage of the aorta or other blood vessels, high blood pressure and connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.
Apcin-OZ Tablet consists of Levofloxacin, a quinolone antibiotic that may cause hypoglycaemia (low blood sugar levels) or hyperglycaemia (high blood sugar levels). It is advised to consult your doctor before using Apcin-OZ Tablet and monitor your blood sugar levels regularly.
Do not stop using Apcin-OZ Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.
Apcin-OZ Tablet contains a quinolone antibiotic, Levofloxacin that can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Apcin-OZ Tablet if you are undergoing any vaccinations.
Antacids and multivitamins with minerals can decrease the efficacy of Apcin-OZ Tablet . Hence, it is recommended to take Apcin-OZ Tablet 2 to 4 hours before or 4 to 6 hours after taking magnesium/aluminium antacids, sucralfate, zinc or iron preparations, and multivitamins with minerals.
You are recommended to take Apcin-OZ Tablet for as long as it is advised by your doctor for effective results. If your symptoms continue or worsen, seek further advice from your doctor.
Inform your doctor if your symptoms are not relieved after completing the full course of Apcin-OZ Tablet . If you notice any undesirable effects that bother you while taking Apcin-OZ Tablet , consult your doctor and seek medical advice.
If you miss taking a dose of Apcin-OZ Tablet , then take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue taking your regular dose. Do not double the dose to make up for the missed one to reduce side effects.
Apcin-OZ Tablet causes side effects such as nausea, loss of appetite, constipation, diarrhoea, trouble sleeping, dizziness and headache. Contact a doctor if these side effects persist for longer durations.
You should avoid consuming large amounts of dairy products, such as milk, yoghurt, or cheese, at the same time as taking Apcin-OZ Tablet . Calcium can bind to the medication in your digestive tract, preventing it from being fully absorbed. It is best to space dairy intake at least 2 hours apart from your dose. Talk to your doctor or pharmacist if you have dietary concerns.
Alcohol must be strictly avoided during treatment and for at least three days after your last dose. Combining alcohol with this medicine can trigger a severe reaction causing rapid heart rate, hot flashes, severe headache, nausea, and vomiting. Talk to your doctor if you have questions about this interaction.
Yes, this medication can make your skin significantly more sensitive to ultraviolet (UV) light. You may sunburn much more easily. Avoid direct sun exposure, tanning beds, and sunlamps while taking this medicine. Wear protective clothing and apply a high-SPF sunscreen when going outdoors. Talk to your doctor if you experience a severe sunburn or skin rash.
Stop taking the medicine immediately, rest the affected area, and contact your healthcare provider right away. This class of medicine carries a risk of tendon inflammation and rupture, especially in the Achilles tendon. Avoid any strenuous exercise until you are evaluated. Talk to your doctor for an alternative treatment plan.
This medicine is generally not recommended during pregnancy or while breastfeeding unless your doctor decides it is absolutely necessary. The active ingredients can pass into breast milk and may affect the development of the baby's joints and bones. Talk to your doctor to weigh the risks and benefits of other safer alternatives.
Yes, some people may experience dizziness, drowsiness, or a spinning sensation while taking this medicine. Avoid driving, operating machinery, or performing tasks that require mental alertness until you know how this medicine affects you. Talk to your doctor if these symptoms persist or worsen.

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Country of origin

India

Manufacturer/Marketer address

No. 8/2, Sarvpriya Vihar, Sarvapriya Vihar, New Delhi-110016, Delhi, India
Other Info - APC0089
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