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Composition :

ARIPIPRAZOLE-10MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apiz-10 mg Tablet

 Apiz-10 mg Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Apiz-10 mg Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterised by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Apiz-10 mg Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Apiz-10 mg Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Apiz-10 mg Tablet improves mood swings, depression, and other psychotic problems. 

Take Apiz-10 mg Tablet as prescribed. Your doctor will advise you on how often to take Apiz-10 mg Tablet , based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Apiz-10 mg Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Apiz-10 mg Tablet or any other medicines, please tell your doctor. Apiz-10 mg Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions, including dizziness, difficulty moving and maintaining balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Apiz-10 mg Tablet if you are pregnant or breastfeeding, and consult a doctor. Apiz-10 mg Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Apiz-10 mg Tablet , please get in touch with a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Apiz-10 mg Tablet .

Uses of Apiz-10 mg Tablet

Apiz-10 mg Tablet is primarily used in the treatment of schizophrenia. Its specific uses are as follows:<br/> • Schizophrenia: Apiz-10 mg Tablet is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.<br/> • Bipolar I Disorder (Manic Depression): Apiz-10 mg Tablet is used alone or in combination with mood stabilizers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilize mood and reduce irritability and hyperactivity.<br/> • Major Depressive Disorder (MDD) - As Adjunctive Therapy: Apiz-10 mg Tablet is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.<br/> • Tourette Syndrome (TS): Apiz-10 mg Tablet is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.<br/> • Autism Spectrum Disorder (ASD): Apiz-10 mg Tablet is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.<br/> • Maintenance Treatment: Apiz-10 mg Tablet is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.<br/>

Directions for Use

  • Apiz-10 mg Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Apiz-10 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Apiz-10 mg Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Apiz-10 mg Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Apiz-10 mg Tablet improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities. Apiz-10 mg Tablet may be used in combination with other medicines to treat depression. Additionally, Apiz-10 mg Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

How Apiz-10 mg Tablet Works

Apiz-10 mg Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Apiz-10 mg Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Apiz-10 mg Tablet improves mood swings, depression, and other psychotic problems.

Storage

Store in a cool and dry place away from sunlight
Side effects of Apiz-10 mg Tablet
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of Apiz-10 mg Tablet

Do not take more than the prescribed dose of Apiz-10 mg Tablet , as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Apiz-10 mg Tablet or any other medicines, please tell your doctor. Apiz-10 mg Tablet should be used with caution in elderly patients above 65 years of age, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Apiz-10 mg Tablet if you are pregnant or breastfeeding, and consult a doctor. Apiz-10 mg Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Apiz-10 mg Tablet , please get in touch with a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking Apiz-10 mg Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Apiz-10 mg Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Apiz-10 mg Tablet:
Co-administration of Metoclopramide with Apiz-10 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Apiz-10 mg Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Apiz-10 mg Tablet:
Combining Apiz-10 mg Tablet with Tetrabenazine can increase the risk of side effects.

How to manage the interaction:
Taking Apiz-10 mg Tablet with Tetrabenazine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleEsketamine
Severe
How does the drug interact with Apiz-10 mg Tablet:
Using Esketamine together with Apiz-10 mg Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Apiz-10 mg Tablet with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without talking to a doctor.
AripiprazoleIomeprol
Severe
How does the drug interact with Apiz-10 mg Tablet:
Coadministration of Apiz-10 mg Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Apiz-10 mg Tablet and Iomeprol, you can take these medicines together if prescribed by a doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Apiz-10 mg Tablet:
Taking carbamazepine and Apiz-10 mg Tablet together can reduce the effects of Apiz-10 mg Tablet which may make the medication less effective.

How to manage the interaction:
Taking carbamazepine and Apiz-10 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AripiprazoleMitotane
Severe
How does the drug interact with Apiz-10 mg Tablet:
When Apiz-10 mg Tablet and Mitotane are taken together, may decrease the blood levels of Apiz-10 mg Tablet, which may make Apiz-10 mg Tablet less effective in treating your condition

How to manage the interaction:
There may be a possibility of interaction between Apiz-10 mg Tablet and Mitotane, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Apiz-10 mg Tablet:
Taking rifabutin with Apiz-10 mg Tablet can reduce the blood levels of Apiz-10 mg Tablet.

How to manage the interaction:
Although taking Apiz-10 mg Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Apiz-10 mg Tablet:
Phenytoin may decrease the blood levels of Apiz-10 mg Tablet, which may make Apiz-10 mg Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Phenytoin and Apiz-10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Apiz-10 mg Tablet:
Co-administration of Apiz-10 mg Tablet with tramadol can increase the risk of irregular heart rhythms, breathing problems.

How to manage the interaction:
Taking Apiz-10 mg Tablet with tramadol together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Apiz-10 mg Tablet:
Using ketamine together with Apiz-10 mg Tablet may increase risk of side effects.

How to manage the interaction:
Co-administration of Ketamine with Apiz-10 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - feeling dizzy, tired, confused, having trouble focusing, feeling too sleepy, or having trouble breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Apiz-10 mg Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
  • Cut down sugars, salt, and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Engage in regular exercise and maintain a stable weight, as Apiz-10 mg Tablet may contribute to weight gain.
  • Avoid alcohol consumption, as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Apiz-10 mg Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Apiz-10 mg Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Apiz-10 mg Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Apiz-10 mg Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Apiz-10 mg Tablet .

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Liver

Caution

Take Apiz-10 mg Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Apiz-10 mg Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Apiz-10 mg Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Apiz-10 mg Tablet to children.

Have a query?

FAQs

Apiz-10 mg Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.

Apiz-10 mg Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Apiz-10 mg Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Apiz-10 mg Tablet improves behaviour, thoughts, and helps in having a better social life, enabling one to comfortably perform daily activities.

No, you are not recommended to take Apiz-10 mg Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Apiz-10 mg Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Apiz-10 mg Tablet with other medicines.

Apiz-10 mg Tablet may cause weight gain in some patients, but it is not a necessary side effect for everyone taking Apiz-10 mg Tablet . However, to avoid gaining weight while taking Apiz-10 mg Tablet , it is advisable to engage in regular exercise and limit high-calorie drinks. Instead, opt for non-alcoholic beverages, herbal tea, and lemon water.

Apiz-10 mg Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Apiz-10 mg Tablet .

Yes, Apiz-10 mg Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Apiz-10 mg Tablet and inform your doctor if you have diabetes before taking Apiz-10 mg Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.

No, you are not recommended to stop taking Apiz-10 mg Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Apiz-10 mg Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Apiz-10 mg Tablet , please consult your doctor so that the dose can be gradually reduced.

Yes, Apiz-10 mg Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.

Apiz-10 mg Tablet might start working within a few days or weeks. However, you may notice the full benefits of Apiz-10 mg Tablet after 2-3 months. Continue taking Apiz-10 mg Tablet for the prescribed duration to prevent the recurrence of symptoms.

Apiz-10 mg Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

Elderly patients more than 65 years old with dementia-related psychosis treated with Apiz-10 mg Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Apiz-10 mg Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.

Avoid intake of grapefruit juice with Apiz-10 mg Tablet as it may reduce the effect of Apiz-10 mg Tablet . Also, avoid alcohol consumption with Apiz-10 mg Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Apiz-10 mg Tablet .

Consult the doctor if you are diabetic, as Apiz-10 mg Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.

Apiz-10 mg Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Apiz-10 mg Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - API0084

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