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Aplet 60 mg Tablet 60's is used to treat prostate cancer. Prostate cancer is a form of cancer that begins in the prostate gland cells in men. It contains Apalutamide, which works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Aplet 60 mg Tablet 60's may cause side effects such as fatigue, headache, diarrhoea, muscle pain, hot flushes, loss of appetite, and skin rash.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

APALUTAMIDE-60MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Aplet 60 mg Tablet 60's

Aplet 60 mg Tablet 60's is a prescription medication used to treat patients with prostate cancer that has not spread to other parts of the body but no longer responds to hormone-lowering treatments, or prostate cancer that has spread and still responds to these treatments. This medicine helps slow down the growth and spread of cancer cells in the body.

You should take this medicine once daily, at the same time each day, to keep a steady level of the drug in your body. You can take the tablets with or without food, swallowing them whole with a glass of water. Combining this treatment with regular physical activity and a balanced diet can help support your muscle strength and overall energy levels.

While taking Aplet 60 mg Tablet 60's, you may experience common side effects like extreme tiredness, joint pain, or hot flashes. If you develop severe side effects, such as a skin rash, chest pain, or sudden dizziness, you should consult your doctor immediately.

Before starting this medicine, tell your doctor if you have a history of seizures, brain injury, heart disease, high blood pressure, or diabetes. Do not take this if you are pregnant, planning to become pregnant, or are a woman of childbearing potential, as this medicine can cause severe harm to an unborn baby.

This medication can interact with other prescription medicines, including certain blood thinners and seizure drugs, by changing how your body processes them. It is also important to talk to your doctor about your alcohol intake, as combining alcohol with this medicine can increase the risk of dizziness or falls. Men with female partners of childbearing potential must use highly effective birth control during treatment and for 3 months after the last dose.

Uses of Aplet 60 mg Tablet 60's

Aplet 60 mg Tablet 60's is used to treat patients with prostate cancer that has not spread to other parts of the body but no longer responds to hormone-lowering treatments. The detailed uses of Aplet 60 mg Tablet 60's are as follows:

  • Non-metastatic castration-resistant prostate cancer (nmCRPC): Aplet 60 mg Tablet 60's helps by delaying the time it takes for the cancer to spread to other parts of the body in men whose prostate cancer no longer responds to medical or surgical treatments that lower testosterone.
  • Metastatic castration-sensitive prostate cancer (mCSPC): Aplet 60 mg Tablet 60's is used alongside hormone therapy to help control and slow down the spread of prostate cancer that has already spread to other areas of the body but still responds to testosterone-lowering treatments.

Key Benefits

Aplet 60 mg Tablet 60's helps treat advanced prostate cancer by blocking the effects of male hormones that promote cancer growth. With regular use as prescribed, it helps slow disease progression, prolong survival, and support better quality of life.

  • Slows the Progression of Prostate Cancer: By blocking the action of male hormones that fuel cancer growth, this medicine helps delay the spread and progression of advanced prostate cancer.
  • Supports Longer Survival: Effective disease control helps improve overall survival and provides a valuable treatment option for patients with advanced prostate cancer.
  • Helps Maintain Daily Functioning: By slowing cancer progression, this medicine helps preserve physical function, reduce disease-related symptoms, and support a better quality of life, allowing you to continue your daily activities more comfortably.
Side effects of Aplet 60 mg Tablet
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Consult a mental health professional trained in eating disorder care for talk therapy.
  • Take a registered dietician help for nutrition education and meal planning.
  • Your doctor may also recommend some medications to treat eating disorder.
  • Parents may supervise meals for young people who still live at home.

Directions for Use

  • Take Aplet 60 mg Tablet 60's with or without food or as advised by a doctor.
  • Recommended to take once daily or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Aplet 60 mg Tablet 60's Works

Aplet 60 mg Tablet 60's contains apalutamide, which works by blocking the action of male hormones, known as androgens (including testosterone), which prostate cancer cells need to grow and multiply. It binds directly to the androgen receptors inside the cancer cells, acting like a shield that prevents these hormones from connecting with the cells. Once this connection is blocked, the medicine stops the hormones from sending signals that tell the cancer cells to grow, divide, and survive. By cutting off this crucial growth signal, the medication helps shrink the tumour or slow down its growth, keeping the disease under control.
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Alcohol

Consult your doctor

The interaction of Aplet 60 mg Tablet 60's with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Aplet 60 mg Tablet 60's may cause seizures. Do not drive vehicles or operate machinery until you know how this medication affects you.

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Liver

Consult your doctor

Insufficient data available on the use of Aplet 60 mg Tablet 60's in patients with liver impairment. If you have liver problems, inform your doctor before taking Aplet 60 mg Tablet 60's.

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Kidney

Consult your doctor

The effect of Aplet 60 mg Tablet 60's in patients with kidney impairment is unknown. If you have kidney disease, inform your doctor before taking Aplet 60 mg Tablet 60's.

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Children

Unsafe

Aplet 60 mg Tablet 60's is not recommended for use in children as the safety and efficacy of this medicine are not established.

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Heart

Caution

Aplet 60 mg Tablet 60's may increase the risk of heart problems. Therefore, please consult your doctor if you have any heart-related problems before using Aplet 60 mg Tablet 60's.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Aplet 60 mg Tablet 60's to geriatric patients. Your doctor will prescribe Aplet 60 mg Tablet 60's if the benefits outweigh the risks.

What if I have taken an overdose of Aplet 60 mg Tablet 60's

If you suspect an overdose or have taken more than your prescribed dose, seek emergency medical attention.

Diet & Lifestyle Advise

  • Focus on bone health: Because this treatment can weaken your bones, include calcium-rich foods like dairy products, leafy greens, and fortified foods in your diet. Talk to your doctor about taking calcium and vitamin D supplements.
  • Engage in regular weight-bearing exercise: Activities like walking, climbing stairs, or light weight training can help strengthen your bones, maintain muscle mass, and combat the extreme tiredness associated with treatment.
  • Monitor your heart health: Eat a heart-healthy diet low in saturated fats and sodium to manage your blood pressure and cholesterol levels, as this medication can increase cardiovascular risks.
  • Take precautions to prevent falls: Ensure your home is free of tripping hazards, use nightlights, and take your time when standing up to avoid falls, especially since this medication can increase the risk of bone fractures.
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How Soon It Starts Working

The time required for Aplet 60 mg Tablet 60's to start to work: The time required for Aplet 60 mg Tablet 60's to show its action is not clinically established. The time for which the effects of Aplet 60 mg Tablet 60's last: The duration of action for Aplet 60 mg Tablet 60's is not clinically established.

What if you forget to take Aplet 60 mg Tablet 60's

If you miss a dose, take it as soon as you remember on the same day. If you do not remember until the next day, skip the missed dose and take your next dose at your regular scheduled time. Do not take a double dose to make up for a missed one.

Storage

• Keep the tablets in their original packaging to protect them from moisture and light.

Drug Warnings

  • Watch for seizure warning signs: Since this medicine carries a risk of seizures, avoid activities where a sudden loss of consciousness could cause serious harm to yourself or others.
  • Use effective contraception: If you are sexually active with a female partner who can become pregnant, use a highly effective condom along with another form of birth control during treatment and for 3 months after your final dose.
  • Monitor your skin closely: If you develop any skin rash, itching, or redness, contact your healthcare provider immediately, as rashes can occasionally become severe.
  • Do not share this medicine: Aplet 60 mg Tablet 60's is prescribed specifically for you; sharing it with others can lead to severe health complications.
  • Keep all medical appointments: Your doctor will need to monitor your blood pressure, heart health, and bone density regularly while you are taking this medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood Thinners: Taking Aplet 60 mg Tablet 60's together with blood thinners, such as warfarin, may increase the risk of bleeding. Your doctor may recommend closer monitoring or adjust your treatment if these medicines are used together.
  • Seizure Medicines: Aplet 60 mg Tablet 60's may interact with certain medicines used to treat seizures, potentially reducing their effectiveness or increasing the risk of side effects. Your doctor may monitor your treatment and adjust the dose if necessary.
  • Medicines Processed by the Liver: Aplet 60 mg Tablet 60's may affect how your liver processes certain medicines, which can alter their blood levels and either reduce their effectiveness or increase the risk of adverse reactions. Inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking before starting treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • There are no known significant food interactions with Aplet 60 mg Tablet 60's when taken as directed. Follow your doctor's advice regarding food intake during treatment.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Aplet 60 mg Tablet 60's is used to treat Prostate cancer.
Aplet 60 mg Tablet 60's contains Apalutamide, which works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.
No, do not stop taking Aplet 60 mg Tablet 60's without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms resolve.
Take Aplet 60 mg Tablet 60's as advised by your doctor. However, if you forget or miss any dose of Aplet 60 mg Tablet 60's, take it as soon as you remember unless it is time for your next dose. But do not double the dose.
Yes, you can take Aplet 60 mg Tablet 60's with or without food. It is best to swallow the tablets whole with a glass of water at the same time each day. If you have any questions about how to take your medicine, talk to your doctor or pharmacist.
You should contact your healthcare provider right away if you notice a skin rash. Rashes are a common side effect, but they can occasionally become severe and require medical management. Talk to your doctor or pharmacist for guidance.
Some patients may experience thinning of the hair or hair loss while taking this medication, as it affects male hormones in the body. If this concerns you, talk to your doctor or pharmacist.
You should use caution when driving or operating machinery because this medication can cause extreme tiredness, dizziness, and increase the risk of seizures. If you feel dizzy or unusually tired, avoid driving and talk to your doctor or pharmacist.
No, Aplet 60 mg Tablet 60's is not prescribed for women. It can cause severe harm to an unborn baby if a pregnant woman is exposed to it. If you have questions about who can take this medicine, talk to your doctor or pharmacist.
This medicine can cause side effects like dizziness, extreme tiredness, and weakened bones, which together can make you more prone to losing your balance and falling. To learn how to prevent falls, talk to your doctor or pharmacist.
Taking too much of this medicine can increase your risk of severe side effects, including seizures. If you take more than your prescribed dose, seek emergency medical care immediately. Talk to your doctor or pharmacist if you are unsure of your dosage.

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Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - APL0119
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