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  3. Aposan Injection 2 ml

Aposan Injection 2 ml, Pack of 1
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Composition :

APOMORPHINE-10MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Aposan Injection 2 ml

Aposan Injection 2 ml belongs to a class of drugs called dopamine agonists. It is used for the acute, intermittent treatment of hypomobility, and off-episodes associated with Parkinson’s disease. Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements.

Aposan Injection 2 ml contains Apomorphine, which belongs to the class of non-ergoline dopamine agonists. It works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement.

Aposan Injection 2 ml may cause certain side effects such as sleepiness, yawning, nausea, vomiting, dizziness, hallucinations, injection site reactions, and leg swelling. Most of these side effects do not require medical attention and will resolve gradually over time. Aposan Injection 2 ml will be administered by a trained healthcare doctor.

Inform your doctor if you develop any allergic reactions after receiving Aposan Injection 2 ml. It is advised not to stop Aposan Injection 2 ml on your own. Consult your doctor if you are pregnant or breastfeeding. Always try to get up slowly from sitting or lying position as Aposan Injection 2 ml may cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Aposan Injection 2 ml is not recommended for use in children below 18 years of age.

Uses of Aposan Injection 2 ml

Aposan Injection 2 ml is used in the treatment of Parkinson's disease. The detailed use of Aposan Injection 2 ml is as follows:<br/>• Treatment of Parkinson's disease: Aposan Injection 2 ml is used to relieve sudden, temporary symptoms like stiffness, tremors, and difficulty moving that occur when Parkinson's medication wears off in people with advanced Parkinson's disease. It's designed for intermittent use to manage these unpredictable episodes and improve mobility.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Aposan Injection 2 ml is typically given by a healthcare provider or self-administered with proper training.• It is administered subcutaneously (under the skin).

Medicinal Benefits

Aposan Injection 2 ml belongs to a group of dopamine agonists used to treat Parkinson’s disease in adults. Aposan Injection 2 ml works by stimulating the dopamine receptors in the brain. This triggers the nerve impulses in the brain that control body movements. Dopamine is a naturally occurring neurotransmitter in the brain which is absent or reduced in people with Parkinson’s disease.

How Aposan Injection 2 ml Works

Aposan Injection 2 ml contains Apomorphine, which belongs to the class of non-ergoline dopamine agonists. It works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aposan Injection 2 ml
  • Avoid caffeine, large reflections, and alcohol close to bedtime.
  • Establish a harmonious sleep schedule.
  • Exercise regularly and maintain a healthy weight.
  • Remove electronic instruments from the bedroom.
  • Increase physical exertion during the day.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.

What if I have taken an overdose of Aposan Injection 2 ml

As Aposan Injection 2 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

To treat your condition effectively, continue receiving Aposan Injection 2 ml for the period that your doctor has prescribed. Do not take Aposan Injection 2 ml if you are allergic to any of its contents. Talk to your doctor if you have any history of kidney/liver problems, hallucinations, dystonia (inability to keep the neck straight), depression, psychosis, vision impairment, and heart disease before receiving Aposan Injection 2 ml. Aposan Injection 2 ml may cause dyskinesia (abnormal limb movements), falling asleep frequently, prolonged QT intervals, hallucinations, syncope, haemolytic anaemia, impulsive behaviour, and coronary problems in some patients. Hence, inform your doctor if you experience symptoms such as anxiety, depression, fatigue, sweating or pain after dose reduction or stopping the medicine. Aposan Injection 2 ml may cause drowsiness and dizziness; do not drive unless you are alert. Aposan Injection 2 ml should not be given to children below 18 years. Avoid consuming alcohol along with Aposan Injection 2 ml as it may cause increased drowsiness and dizziness. Always try to get up slowly from sitting or lying position as Aposan Injection 2 ml causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions

verifiedApollotooltip
ApomorphineZiprasidone
Critical
ApomorphineCeritinib
Severe

Drug-Drug Interactions

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ApomorphineZiprasidone
Critical
How does the drug interact with Aposan Injection 2 ml:
Co-administration of Aposan Injection 2 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Aposan Injection 2 ml but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ApomorphineCeritinib
Severe
How does the drug interact with Aposan Injection 2 ml:
Coadministration of Aposan Injection 2 ml with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Aposan Injection 2 ml together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ApomorphineDisopyramide
Severe
How does the drug interact with Aposan Injection 2 ml:
The combined use of Aposan Injection 2 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Aposan Injection 2 ml and Disopyramide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
ApomorphineMoxifloxacin
Severe
How does the drug interact with Aposan Injection 2 ml:
Using Moxifloxacin together with Aposan Injection 2 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Aposan Injection 2 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizzy, fast or irregular heartbeat, feeling short of breath contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ApomorphineMifepristone
Severe
How does the drug interact with Aposan Injection 2 ml:
Co-administration of Aposan Injection 2 ml with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Aposan Injection 2 ml with mifepristone together is avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
ApomorphineSotalol
Severe
How does the drug interact with Aposan Injection 2 ml:
Combining Aposan Injection 2 ml together with Sotalol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
There may be a possibility of interaction between Sotalol and Aposan Injection 2 ml, but it can be taken if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor. Do not stop using any medications without a doctor's advice.
ApomorphineHaloperidol
Severe
How does the drug interact with Aposan Injection 2 ml:
Co-administration of Aposan Injection 2 ml with Haloperidol can increase the risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Aposan Injection 2 ml with Haloperidol together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting your doctor.
ApomorphineGatifloxacin
Severe
How does the drug interact with Aposan Injection 2 ml:
Taking Gatifloxacin with Aposan Injection 2 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Aposan Injection 2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApomorphineGranisetron
Severe
How does the drug interact with Aposan Injection 2 ml:
Taking Granisetron with Aposan Injection 2 ml can increase the risk of low blood pressure.

How to manage the interaction:
Co-administration of Granisetron with Aposan Injection 2 ml can result in an interaction, but it can be taken if a doctor has advised it. If you are taking these medications together, it is important to be careful and watch out for low blood pressure. If you notice any symptoms like lightheadedness, loss of consciousness, chest discomfort or heaviness, or shaking movements, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

Aposan Injection 2 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Aposan Injection 2 ml as it may cause increased dizziness.

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Pregnancy

Caution

Studies on humans or animals have not determined whether apomorphine is safe to use while pregnant. It is, therefore, not appropriate for women who are pregnant or who are likely to become pregnant to use Aposan Injection 2 ml. Inform your doctor if you are pregnant.

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Breast Feeding

Caution

The excretion of apomorphine in breast milk is unknown despite the lack of reported issues in humans. However, considering the advantages of both breastfeeding and medicine for the mother, a decision should be made regarding whether to stop breastfeeding or take the medication. Hence, inform your doctor if you are breastfeeding before taking Aposan Injection 2 ml.

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Driving

Unsafe

Aposan Injection 2 ml may cause dizziness, sleepiness and hallucinations. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Aposan Injection 2 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Aposan Injection 2 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Aposan Injection 2 ml is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

Have a query?

FAQs

Aposan Injection 2 ml is used to treat Parkinson’s disease.

Aposan Injection 2 ml works by acting like dopamine and triggering the nerve impulses in the brain that control our body movements.

Aposan Injection 2 ml may cause peripheral oedema (swelling of the lower legs and hands due to fluid overload). So, avoid sitting or standing for too long.

Country of origin

India

Manufacturer/Marketer address

58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai 400 067 (India).
Other Info - APO0087

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a604020.html
  2. https://go.drugbank.com/drugs/DB00714
  3. https://www.drugs.com/apomorphine.html
  4. https://www.parkinsons.org.uk/information-and-support/apomorphine
  5. https://reference.medscape.com/drug/apokyn-kynmobi-apomorphine-343040
  6. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021264s022lbl.pdf

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