Arpimune ME 50 Tablet 5's
MRP ₹218
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About Arpimune ME 50 Tablet
Arpimune ME 50 Tablet belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.
Arpimune ME 50 Tablet contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.
Arpimune ME 50 Tablet may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.
To treat your condition effectually, continue taking Arpimune ME 50 Tablet for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.
Uses of Arpimune ME 50 Tablet
Arpimune ME 50 Tablet is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Arpimune ME 50 Tablet are as follows:
- Treatment of Organ Transplant Rejection: Arpimune ME 50 Tablet is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
- Treatment of Psoriasis: Arpimune ME 50 Tablet is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
- Treatment of Rheumatoid Arthritis: Arpimune ME 50 Tablet is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.
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Directions for Use
- Arpimune ME 50 Tablet can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Check the label for directions and use as advised by your doctor.
- Measure the prescribed dose of Arpimune ME 50 Tablet using the dosing syringe. Mix it with apple or orange juice, stir well, and drink immediately.
- Do not store the prepared mixture for later use.
Key Benefits
- Arpimune ME 50 Tablet suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
- It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
- Arpimune ME 50 Tablet helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
- It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
- This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
- It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
- Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
- It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.
How Arpimune ME 50 Tablet Works
Storage
- Get plenty of fresh air.
- Take regular sips of a cold drink.
- Take ginger containing foods like ginger tea and ginger biscuits.
- Do not take heavy meals at a time, take small and frequent meals.
- Confusion is a major psychotic disorder that needs immediate medical attention.
- Acknowledge your experience and put effort to control confusion.
- Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
- Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
- Talk to your dietician and consume food that can improve your mental health.
- Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
- A warm compress and washing the eyes with water can help with crusting on the eyelids.
- Avoid wearing contact lens until you feel better; use spectacles instead.
- Do not rub the eyes.
- Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
- Reduce salt intake to minimize fluid buildup.
- Use compression stockings, sleeves, or gloves.
- Gently massage the affected area towards the heart.
- Protect the swollen area from injury and keep it clean.
- Use lotion or cream to keep the skin moisturized.
- Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
- Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
- Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
- Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
- Keep your nails short to reduce the risk of breakage and snagging.
- Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
- Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.
What if I have taken an overdose of Arpimune ME 50 Tablet
Drug Warnings
- Do not take Arpimune ME 50 Tablet if you are allergic to any of the components.
- Let your doctor know before using Arpimune ME 50 Tablet if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
- Arpimune ME 50 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
- Before taking Arpimune ME 50 Tablet, inform your doctor if you have any type of cancer.
- Consult your doctor before taking Arpimune ME 50 Tablet if you are pregnant or planning for pregnancy.
- Arpimune ME 50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk.
- Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Drug-Drug Interactions
Drug-Drug Interactions
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When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Arpimune ME 50 Tablet with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Combining Arpimune ME 50 Tablet and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Arpimune ME 50 Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Arpimune ME 50 Tablet with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Arpimune ME 50 Tablet with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Coadministration of pitavastatin with Arpimune ME 50 Tablet may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Arpimune ME 50 Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Using cladribine together with Arpimune ME 50 Tablet may increase the risk of infections.
How to manage the interaction:
Although taking cladribine and Arpimune ME 50 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Co-administration of colchicine with Arpimune ME 50 Tablet may increases the blood levels and effects of both medications.
How to manage the interaction:
Although there is a possible interaction between colchicine and Arpimune ME 50 Tablet, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as abdominal pain, diarrhoea, fever, muscle pain, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.
How to manage the interaction:
There may be a possibility of interaction between cisapride and Arpimune ME 50 Tablet, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
Co-administration of Arpimune ME 50 Tablet with mifepristone may significantly increase the blood levels of Arpimune ME 50 Tablet which may increase the risk and/or severity of side effects.
How to manage the interaction:
Although taking Arpimune ME 50 Tablet and Mifepristone together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.
Coadministration of docetaxel with Arpimune ME 50 Tablet may significantly increase the blood levels of docetaxel.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Arpimune ME 50 Tablet, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit Juice, Grapefruit
How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Arpimune ME 50 Tablet can increase the effects of Arpimune ME 50 Tablet. Avoid consuming grapefruit and grapefruit juice while taking Arpimune ME 50 Tablet.
Diet & Lifestyle Advise
- Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
- Consuming food rich in probiotics helps in developing the immune system against allergies.
- Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
- Avoid consumption of foods with excess sugar to prevent flare-up inflammation.
- Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
- Reducing stress and maintaining a regular sleep pattern would be helpful.
- Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
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Alcohol
Safe if prescribed
You are recommended to avoid alcohol consumption while taking Arpimune ME 50 Tablet. It could lead to increased dizziness.
Pregnancy
Consult your doctor
Arpimune ME 50 Tablet belongs to pregnancy category C. Consult your doctor before taking Arpimune ME 50 Tablet if you are pregnant or planning for pregnancy.
Breast Feeding
Consult your doctor
Arpimune ME 50 Tablet passes into breast milk. Avoid breastfeeding while taking Arpimune ME 50 Tablet.
Driving
Safe if prescribed
Arpimune ME 50 Tablet may cause dizziness. Drive or operate machinery only if you are alert.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Arpimune ME 50 Tablet is not recommended for children as efficacy and safety have not been established.
Heart
Please inform your doctor if you have any pre-existing heart problems
Geriatrics
Consult your doctor
Arpimune ME 50 Tablet should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.
FAQs
Arpimune ME 50 Tablet is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.
Arpimune ME 50 Tablet acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.
If you miss a dose of Arpimune ME 50 Tablet, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.
Diarrhoea might be a side effect of Arpimune ME 50 Tablet. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, the use of Arpimune ME 50 Tablet may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.
Arpimune ME 50 Tablet is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and using sunscreen regularly.
Arpimune ME 50 Tablet may cause high blood pressure. Therefore, consult the doctor before taking Arpimune ME 50 Tablet if you have high blood pressure.
No, Arpimune ME 50 Tablet is not a steroid. It is an immunosuppressant.
Arpimune ME 50 Tablet may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.
Arpimune ME 50 Tablet may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.
Yes, your doctor will recommend certain tests to check your body’s response to Arpimune ME 50 Tablet.
Arpimune ME 50 Tablet may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.
Use the measuring cup/dosing syringe provided with the pack to measure the prescribed dose of Arpimune ME 50 Tablet. Mix the solution/suspension in a glass of milk or orange juice, stir well, and consume immediately. Do not store the prepared mixture for later use.
You are advised to take Arpimune ME 50 Tablet for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050715s035,050716s038lbl.pdf
- https://www.drugs.com/disease-interactions/cyclosporine.html
- https://www.medicines.org.uk/emc/files/pil.5300.pdf
- https://www.medicines.org.uk/emc/files/pil.1034.pdf
- https://www.webmd.com/drugs/2/drug-5645-9108/cyclosporine-oral/cyclosporine-oral/details
