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compositionComposition:NAPROXEN-250MG+PANTOPRAZOLE-20MG
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Arthopan 250 mg Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical spondylitis, dysmenorrhea, mild migraine and acute gout. It contains Naproxen and Pantoprazole which work by inhibiting chemical messengers that cause pain. Besides this, it also prevents acidity-related problems related to painkillers. This medicine may sometimes cause side effects such as indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NAPROXEN-250MG+PANTOPRAZOLE-20MG

Manufacturer/Marketer :

Crescent Therapeutics Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Arthopan 250 mg Tablet

Arthopan 250 mg Tablet is used to relieve pain, swelling, and stiffness caused by joint conditions like arthritis. It is specially designed for individuals who need long-term pain relief but are at high risk of developing painful stomach ulcers from standard pain relievers.

Arthopan 250 mg Tablet is typically taken twice daily, at least 30 minutes before meals, to ensure the acid-protecting component works effectively. Taking this medicine consistently at the same times every day helps maintain stable relief. Making small dietary adjustments, like eating smaller, non-spicy meals, can also support your stomach comfort during treatment.

While taking Arthopan 250 mg Tablet , some people may experience mild side effects like a mild headache, nausea, or mild stomach upset. However, you must contact your doctor immediately if you notice serious symptoms such as severe abdominal pain, black or bloody stools, or unusual swelling in your ankles or feet.

It is important to talk to your doctor before starting Arthopan 250 mg Tablet if you have high blood pressure, heart disease, or liver damage. Do not take this medicine if you have a history of severe allergic reactions to aspirin or other pain relievers, or if you have severe kidney disease or active stomach ulcers.

This medicine can interact with other treatments like blood thinners, which may increase your risk of bleeding. Always consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, as special precautions or alternative options may be needed. 

Uses of Arthopan 250 mg Tablet

Arthopan 250 mg Tablet is used to relieve pain, swelling, and stiffness caused by joint conditions like arthritis. The detailed uses of Arthopan 250 mg Tablet are as follows: 

  • Osteoarthritis: Arthopan 250 mg Tablet helps relieve the chronic pain, joint tenderness, and stiffness associated with the gradual wear and tear of joint cartilage.
  • Rheumatoid Arthritis: It reduces the painful inflammation, swelling, and morning stiffness in the joints caused by this long-term autoimmune condition.
  • Ankylosing Spondylitis: It eases the severe back pain and spinal stiffness linked to this chronic inflammatory arthritis affecting the spine.
  • Stomach Acid Protection: It lowers the risk of developing painful stomach or intestinal ulcers in people who require daily pain management. 

Key Benefits

Arthopan 250 mg Tablet is used to relieve pain, reduce swelling, and improve stiffness associated with joint disorders.

  • Provides effective pain and inflammation relief: Naproxen helps reduce pain, swelling, and stiffness associated with conditions such as arthritis, muscle pain, back pain, and other inflammatory disorders.
  • Protects the stomach from ulcers: Pantoprazole decreases stomach acid production, helping reduce the risk of gastric ulcers, irritation, and bleeding that may occur with long-term or high-dose NSAID use. Pantoprazole reduces but does not eliminate the risk of serious GI events, so regular monitoring is still necessary.
  • Improves treatment tolerability: The combination allows patients who require regular NSAID therapy to receive pain relief while lowering the likelihood of acid-related gastrointestinal side effects.
  • Enhances patient convenience and adherence: Combining both medications in a single formulation simplifies treatment, making it easier to follow the prescribed regimen while managing pain and protecting the stomach. 
Side effects of Arthopan 250 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Arthopan 250 mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Arthopan 250 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Arthopan 250 mg Tablet Works

Arthopan 250 mg Tablet contains two active medicines that work together in harmony to manage pain while keeping your digestive system safe. Naproxen is a pain-relieving medicine that stops your body from producing certain natural chemicals that cause pain, heat, and swelling. By lowering the levels of these chemicals, it directly reduces joint discomfort and stiffness. The second active ingredient is an acid-reducing medicine. Standard pain relievers can weaken the stomach's natural defence barrier, making it vulnerable to acid damage. This second ingredient works by turning down the acid-producing pumps in your stomach, significantly lowering acid levels so your stomach lining can remain healthy and free from ulcers while you manage your pain.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Arthopan 250 mg Tablet as it may increase the risk of stomach bleeding and ulcer.

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Pregnancy

Unsafe

Arthopan 250 mg Tablet is a Category C pregnancy drug and is considered unsafe for pregnant women especially in the third trimester. However, please consult your doctor if you are pregnant.

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Breast Feeding

Caution

Arthopan 250 mg Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Arthopan 250 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

Arthopan 250 mg Tablet may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Arthopan 250 mg Tablet .

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Liver

Caution

Arthopan 250 mg Tablet should be used with caution in people having liver diseases. Dose adjustments may be necessary. So, it should be used only with your doctor's prescription.

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Kidney

Caution

Arthopan 250 mg Tablet is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.

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Children

Unsafe

Arthopan 250 mg Tablet can be used safely in children if prescribed by a doctor.

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Heart

Caution

Arthopan 250 mg Tablet should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Arthopan 250 mg Tablet should be used under caution in geriatric patients due to the risk of kidney/heart/gastrointestinal problems etc. Please consult your physician.

What if I have taken an overdose of Arthopan 250 mg Tablet

If you accidentally take too much of Arthopan 250 mg Tablet , seek immediate medical attention or call your local poison control centre. Symptoms of an overdose may include severe stomach pain, extreme drowsiness, shallow breathing, or vomiting.

Diet & Lifestyle Advise

  • Eat stomach-friendly foods: Focus on a diet rich in non-acidic fruits, vegetables, lean proteins, and whole grains. Avoid spicy, highly acidic, or greasy foods that can irritate your stomach lining.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your digestion and kidney function while taking this medicine.
  • Gentle exercise: Engage in low-impact activities like walking, swimming, or stretching to keep your joints flexible and strong without putting excessive stress on them.
  • Avoid trigger substances: Limit your intake of caffeine, alcohol, and carbonated beverages, as these can increase stomach acid production and worsen joint inflammation.
     
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How Soon It Starts Working

The time required for Arthopan 250 mg Tablet to start to work: Arthopan 250 mg Tablet starts to show its action within 1 hour of administration. The time for which the effects of Arthopan 250 mg Tablet last: Arthopan 250 mg Tablet effect lasts for 24 hours.

What if you forget to take Arthopan 250 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Arthopan 250 mg Tablet at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect Before Use: Always inspect the tablets before taking them; do not use them if they are broken, discoloured, or show signs of dampness.
  • Inform Healthcare Providers: Tell any healthcare provider you visit—including dentists and surgeons—that you are taking Arthopan 250 mg Tablet , as you may need to stop it temporarily before certain procedures.
  • Monitor Blood Pressure: Check your blood pressure regularly while taking this medicine, as the pain-relieving component may increase blood pressure in some people.
  • Avoid Unapproved Medicines: Do not take other over-the-counter pain relievers or acid-reducing medicines unless specifically advised by your doctor.
  • Regular Blood Tests: Have regular blood tests if recommended by your doctor, especially if you need to use this medication for an extended period.
     

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood thinners (like warfarin or aspirin): Taking these with Arthopan 250 mg Tablet can significantly increase your risk of stomach bleeding.
  • Methotrexate: This medicine can raise the levels of methotrexate in your body, increasing the risk of serious side effects.
  • Lithium: Arthopan 250 mg Tablet may increase lithium levels in your blood, which requires close monitoring by your doctor.
  • Other pain relievers or acid reducers: Combining these can lead to an increased risk of side effects or reduce the overall effectiveness of your treatment.
  • SSRIs/SNRIs (e.g., sertraline, fluoxetine, venlafaxine): May increase the risk of gastrointestinal bleeding.
  • ACE inhibitors/ARBs (e.g., lisinopril, ramipril, losartan): NSAIDs may reduce their blood pressure-lowering effect and increase the risk of kidney impairment.
  • Diuretics (e.g., furosemide, hydrochlorothiazide): May reduce diuretic effectiveness and increase the risk of dehydration and kidney injury when used with NSAIDs. 
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: Taking this medicine with a high-fat meal can delay how quickly your body absorbs the active ingredients. It is best taken on an empty stomach, at least 30 minutes before food.
  • Alcohol: Consuming alcohol while taking this medicine significantly increases the risk of stomach irritation and internal bleeding.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Arthopan 250 mg Tablet is used to relieve pain and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical spondylitis, dysmenorrhea, mild migraine and acute gout.
Arthopan 250 mg Tablet contains Naproxen (non-steroidal anti-inflammatory drug or pain reliever) and Pantoprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Pantoprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
No, you are not recommended to take Arthopan 250 mg Tablet with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Yes. Arthopan 250 mg Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such a diagnostics test contact your doctor.
Yes, Naproxen in Arthopan 250 mg Tablet may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Arthopan 250 mg Tablet . However, it is recommended to take Arthopan 250 mg Tablet in dose and for the duration as prescribed by your doctor. It should be not used by the patient who have had recent heart bypass surgery (coronary artery bypass graft - CABG).
Arthritis is a chronic condition of joints with pain and inflammation. Arthopan 250 mg Tablet does not cure arthritis but relieve symptoms of arthritis-like joint pain, swelling and stiffness.
Arthopan 250 mg Tablet is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of egg from ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping Arthopan 250 mg Tablet . However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking Arthopan 250 mg Tablet .
Arthopan 250 mg Tablet can help relieve sinus infection symptoms like pain and inflammation, but it would not fight against the infection. Consult your doctor for appropriate treatment for your sinus infection.
Arthopan 250 mg Tablet can increase blood pressure in some individuals, especially in those with pre-existing hypertension. Monitor your blood pressure regularly and consult your doctor if any concerns arise.
No, Arthopan 250 mg Tablet does not contain sulfa. It is a combination of naproxen, a nonsteroidal anti-inflammatory, and pantoprazole, a proton pump inhibitor (PPI).
Arthopan 250 mg Tablet is generally safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It is important to follow your doctor's instructions and inform them about any pre-existing and existing medical conditions or ongoing medications intake to avoid negative complications.
No. Arthopan 250 mg Tablet is not a narcotic, controlled substance, or habit-forming medicine. It contains naproxen (an NSAID) and pantoprazole (a proton pump inhibitor), neither of which has addictive properties or a high potential for abuse. Use it only as directed by your doctor.
No, Arthopan 250 mg Tablet is not a blood thinner. Both naproxen and pantoprazole in its composition does not have any blood thinning properties. But naproxen may increase bleeding risk, but it doesn't thin blood like anticoagulants do. Consult a doctor for appropriate guidance.
Arthopan 250 mg Tablet can help relieve headache by reducing inflammation and pain. But, consult your doctor for proper diagnosis and treatment.
No, Arthopan 250 mg Tablet is not available over the counter (OTC) and it requires a prescription from a doctor.
No, do not take Arthopan 250 mg Tablet with oxycodone without consulting a doctor. Potential interactions may take place and lead to an increase in the risk of negative effects (like bleeding, stomach ulcers, or respiratory depression). Consult a doctor before taking the medication and they will advise you of safe usage.
No, you are not recommended to take Arthopan 250 mg Tablet with prednisone. This combination may increase the risk of gastrointestinal side effects, such as bleeding, ulcers, and inflammation. It is important to consult your doctor before combining any medications to ensure safety.
Yes, Arthopan 250 mg Tablet under doctor's guidance for painful period cramps. Usually, it helps to treat dysmenorrhea (menstrual cramps) by reducing pain and inflammation.
Generally, Arthopan 250 mg Tablet is not used to treat fever. But, it can reduce the fever which is caused due to the pain and inflammation. However, always consult your doctor for proper diagnosis and treatment.
Arthopan 250 mg Tablet can help to relieve back pain caused by inflammation. However, take it under the doctor's guidance after proper diagnosis.
No, Arthopan 250 mg Tablet is not typically used to treat cold. It is a combination of naproxen, an anti-inflammatory, and pantoprazole, a proton pump inhibitor, mainly used to relieve pain and inflammation. Consult your doctor for appropriate treatment for a cold.
Arthopan 250 mg Tablet can relieve headaches and body aches from hangovers, but it is not specifically prescribed for hangover treatment. For relief, try drinking water, resting and eating a balanced meal. Consult your doctor if symptoms persist.
No, Arthopan 250 mg Tablet is not used to treat gallbladder pain. You should consult a doctor if you have gallbladder pain for proper diagnosis and treatment. They may recommend medications or surgery depending on the underlying cause.
No, Arthopan 250 mg Tablet can helps in providing relief from tonsillitis symptoms like pain, inflammation, and fever. But it does not cure your tonsillitis. However, consult your doctor for proper diagnosis and treatment suitable to your condition.
No, Arthopan 250 mg Tablet may provide relief for UTI symptoms like pain and inflammation only, but it won't treat the underlying infection and does not provide a cure for UTI. Consult your doctor for proper treatment.
Arthopan 250 mg Tablet can provide short-term relief from toothache pain. However, it is necessary to consult your dentist for proper diagnosis and treatment to address the underlying cause.
Yes, Arthopan 250 mg Tablet can cause sleepy or drowsiness in some people. But, it vanishes over time as the body adjusts to the medication. If you experience drowsiness, it is important to avoid driving or operating heavy machinery and have some rest after taking it. If this symptom gets worse, please consult a doctor for relief.
Arthopan 250 mg Tablet typically starts working within an hour to relieve pain and inflammation. However, the full effect may take a little longer depending upon individual health conditions.
Yes, like all medications Arthopan 250 mg Tablet can also expire. Check the packaging for the expiration date. Make sure not to take expired medication.
No, Arthopan 250 mg Tablet does not contain aspirin. It consists naproxen, a nonsteroidal anti-inflammatory drug (NSAID), and pantoprazole, a proton pump inhibitor (PPI).
No, Arthopan 250 mg Tablet does not produce a high. Because it contains naproxen and pantoprazole. Neither of these components does not have psychoactive properties or cause euphoria.
Yes. Arthopan 250 mg Tablet is effective in relieving pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, tendinitis, gout, and menstrual cramps. It contains naproxen, which reduces pain and inflammation, and pantoprazole, which helps protect the stomach by reducing acid production. Take it only as prescribed by your doctor.
No, Arthopan 250 mg Tablet can help to relieve flu symptoms like fever, headache, and body aches, but it won't treat the underlying viral infection. Consult your doctor for proper diagnosis and treatment for your flu.
No, do not take Arthopan 250 mg Tablet without consulting your doctor, as Arthopan 250 mg Tablet may help to reduce pain and inflammation from swollen glands, but your doctor determines the underlying cause for swollen legs and provides you the suitable treatment.
The common side effects of Arthopan 250 mg Tablet which may be experienced in some individuals are indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea in some cases. Most of these side effects of Arthopan 250 mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.
It is best to take PANTOPRAZOLE on an empty stomach, at least 30 minutes before your meal. Taking it with food can delay how quickly the medicine starts to work. Talk to your doctor if you experience stomach upset.
No, you must swallow the tablet whole. Crushing, chewing, or splitting the tablet destroys the protective layer that prevents stomach irritation and ensures the medicine is released correctly. If you have trouble swallowing, talk to your doctor or pharmacist.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can irritate your stomach lining and significantly increase your risk of developing stomach bleeding or ulcers. Talk to your doctor if you have concerns.
Some people may feel dizzy or lightheaded while taking Arthopan 250 mg Tablet . If this happens, sit or lie down until the feeling passes, and avoid driving or operating machinery. If the dizziness persists or worsens, talk to your doctor.
Arthopan 250 mg Tablet should be used during pregnancy only if clearly prescribed by your doctor. NSAID use during the first and second trimesters may increase the risk of miscarriage, fetal kidney problems, and low amniotic fluid (oligohydramnios). Use during the third trimester is contraindicated because it may cause premature closure of the fetal ductus arteriosus, fetal kidney injury, and complications during labor and delivery.
You should avoid taking other non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin while taking Arthopan 250 mg Tablet , as this can greatly increase your risk of severe stomach ulcers and bleeding. Talk to your doctor before taking any new pain medication.
Serious stomach problems while taking Arthopan 250 mg Tablet may include severe or persistent stomach pain, black or tarry stools, blood in the stool, vomiting blood or material that looks like coffee grounds, severe indigestion, unexplained weakness, dizziness, or fainting. These may be signs of stomach bleeding or an ulcer, which require immediate medical attention. Stop taking the medicine and seek emergency medical care or contact your doctor immediately if you experience any of these symptoms.

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Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - ART0025

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