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Composition :

ATROPINE-0.6MG

Manufacturer/Marketer :

Harson Laboratories

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Atropine Injectio

Atropine Injectio is used to treat bradycardia (a condition characterised by a decreased heart rate). Bradycardia is a condition in which the heart beats slower than 60 times per minute, potentially reducing blood flow and oxygen delivery to the body.

Atropine Injectio contains Atropine. It works by blocking the activity of acetylcholine (a chemical messenger). This helps normalise blood pressure, relax the heart, treat symptomatic bradycardia, and prevent sudden drops in blood pressure.

Atropine Injectio may cause common side effects, including constipation, bloating, stomach pain, nausea, vomiting, dry eyes, blurred vision, dry mouth, a fast/pounding heartbeat, flushing (sudden warmth, redness, or a tingling feeling), confusion, headache, dizziness, drowsiness, and thirst. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of the ingredients in Atropine Injectio. Pregnant and breastfeeding women should consult their doctor before using Atropine Injectio. This medicine will be prescribed by a doctor for children, depending on their age and body weight.

Uses of Atropine Injectio

Atropine Injectio is used in the treatment of bradycardia (decreased heart rate). The detailed uses of Atropine Injectio are as follows:

  • Treats Bradycardia: Atropine Injectio is primarily used in emergency settings to increase heart rate in patients with symptomatic bradycardia by blocking the action of acetylcholine (chemical messenger).
  • Supportive Treatment in Cardiac Arrest: Atropine Injectio helps restore a normal heartbeat in cardiac arrest or heart failure patients, especially when bradycardia is a contributing factor.
  • Used as a Preoperative Medication: Atropine Injectio is administered before anaesthesia to reduce salivation and suppress excessive respiratory secretions, minimising the risk of airway obstruction during surgery.
  • Antidote for Poisoning: Atropine Injectio also acts as an antidote in cases of poisoning from organophosphate insecticides, nerve gas, and certain mushrooms by blocking excessive acetylcholine activity caused by these toxins.
  • Reverses Muscle Relaxant Effects Post-Surgery: Atropine Injectio may be used in combination with other medications (like neostigmine) to reverse the effects of muscle relaxants (including salivation and bradycardia) used during surgical procedures.

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Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Atropine Injectio will be administered by a healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • The Atropine Injectio contains Atropine, which is an anticholinergic agent, an antisialagogue (inhibiting the flow of saliva), and an antidote.
  • It is used to treat bradycardia (slow heart rate).
  • It also restores a normal heartbeat in cardiac arrest or failure.
  • It is used as a preoperative medication before anaesthesia to inhibit salivation and excessive secretions of the respiratory tract.
  • It also acts as an antidote to treat organophosphate insecticides, nerve gas, and mushroom poisoning.
  • In combination with other medications, Atropine Injectio is used to counteract the muscle-relaxant effect during surgery.

How Atropine Injectio Works

Atropine Injectio contains Atropine, which belongs to the class of muscarinic antagonists or parasympatholytics. It works by blocking the activity of acetylcholine (a chemical messenger). As a result, this helps to bring back the blood pressure within the normal range and relaxes the heart. Hence, it treats symptomatic bradycardia and prevents sudden falls in blood pressure.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Atropine Injection10 ml
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink enough water throughout the day.
  • Avoid alcohol and caffeine.
  • Take a bath or cool shower frequently.
  • Wear loose-fitted light-coloured clothing.
  • Use a hat to protect yourself from sunlight.
  • Avoid heavy activity or strenuous exercise in hot environments.
  • Consult the doctor if you notice significant decrease in sweating.

What if I have taken an overdose of Atropine Injectio

The overdose of Atropine Injectio is unlikely as it is administered by a doctor. However, in case of overdose, patients may experience a very fast heartbeat, quick breathing, fever, restlessness, confusion, hallucinations or loss of coordination. If you experience these symptoms, please consult a doctor immediately.

Drug Warnings

  • Before using Atropine Injectio, inform your doctor if you have any medical history, including asthma, glaucoma, heart rhythm disorder, liver/kidney diseases, enlarged prostate, stomach diseases or myasthenia gravis (muscle weakness).
  • Atropine Injectio may cause blurred vision, dizziness, and drowsiness; therefore, do not drive or operate machinery until you feel better.
  • Pregnant and breastfeeding women should consult their doctor before using Atropine Injectio.
  • Alcohol consumption may worsen the side effects of Atropine Injectio, like dizziness and drowsiness. Hence, do not consume alcohol.
  • This medicine will be prescribed by a doctor for children, depending on their age and body weight.

Drug-Drug Interactions

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AtropineHydromorphone
Severe

Drug-Drug Interactions

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How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Atropine Injection10 ml is used with solifenacin may cause side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems).

How to manage the interaction:
Co- administration of Atropine Injection10 ml with solifenacin can lead to an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, reduced sweating, trouble urinating, abdominal cramps, constipation, irregular heartbeat, disorientation, and memory issues, consult the doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
AtropineHydromorphone
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Using Hydromorphone together with Atropine Injection10 ml may increase the risk and/or severity of some side effects (dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation).

How to manage the interaction:
Although taking Hydromorphone and Atropine Injection10 ml together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: trouble peeing, feeling dizzy or sleepy, feeling confused or having trouble focusing, dry mouth, constipation, or feeling less mentally sharp. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Atropine Injection10 ml and Topiramate are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atropine Injection10 ml and topiramate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropineUmeclidinium bromide
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Using Atropine Injection10 ml together with umeclidinium may increase side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes).

How to manage the interaction:
Although taking Atropine Injection10 ml and Umeclidinium bromide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes. Do not stop using any medications without talking to a doctor.
AtropinePramlintide
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Coadministration of Pramlintide with Atropine Injection10 ml can increase the risk of reduced movement in the digestive system.

How to manage the interaction:
Taking Atropine Injection10 ml with Pramlintide together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Co-administration of Atropine Injection10 ml with Potassium chloride oral tablets or capsules can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Atropine Injection10 ml and Potassium chloride, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact the doctor right away: severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting(especially with blood), decreased hunger, dark, tarry stools. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Coadministration of Atropine Injection10 ml and Zonisamide can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atropine Injection10 ml and Zonisamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropineSecretin
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Secretin human is used with Atropine Injection10 ml, the therapeutic efficacy of Secretin human can be decrease.

How to manage the interaction:
Although there is a possible interaction between Atropine Injection10 ml and Secretin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtropinePotassium citrate
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Taking potassium citrate oral tablets or capsules with Atropine Injection10 ml may increase the irritating effects of potassium on stomach and upper intestine.

How to manage the interaction:
Taking Atropine Injection10 ml with potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtropineTirzepatide
Moderate
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Atropine Injection10 ml is taken along with tirzepatide it may increase the heart rate.

How to manage the interaction:
Patients on Atropine Injection10 ml should take tirzepatide with caution because both medications may elevate heart rate.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain healthy cholesterol and triglyceride levels.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Monitor your weight and exercise regularly to maintain a healthy heart.
  • Your doctor also guides you on noticing and managing the early symptoms of heart disease.

Habit Forming

Yes

Therapeutic Class

ANTICHOLINERGICS
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Alcohol

Unsafe

Alcohol consumption may worsen the side effects of this medicine, such as dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atropine Injectio.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Atropine Injectio only if the benefits outweigh the risk.

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Breast Feeding

Caution

Please inform your doctor if you are breastfeeding. Your doctor will prescribe Atropine Injectio only if the benefits outweigh the risks.

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Driving

Unsafe

Atropine Injectio may cause side effects like dizziness and drowsiness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Consult your doctor

Consult your doctor if you have any history of liver diseases or hepatic impairment before receiving Atropine Injectio.

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Kidney

Consult your doctor

Consult your doctor if you have any history of kidney diseases/impairment before receiving Atropine Injectio.

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Children

Consult your doctor

Please consult your doctor. Your doctor will determine the dose based on your child's age and condition.

FAQs

Atropine Injectio belongs to a class of drugs known as anticholinergics, which are used to treat bradycardia (a decreased heart rate). It restores a normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.

Atropine Injectio contains Atropine, which is used to treat bradycardia (slow heart rate). It works by blocking the activity of acetylcholine (a chemical messenger). As a result, this helps to bring the blood pressure back within the normal range and relaxes the heart.

Dry mouth could be a side effect of Atropine Injectio. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Atropine may decrease sweating and increase your risk of heat stroke. Hence, it is advisable to avoid becoming overheated or dehydrated during any physical activity, especially in hot weather.

Atropine is contraindicated in allergic reactions, urinary difficulties, elevated pressure in the eye (glaucoma), and stomach-related disorders like achalasia of the oesophagus, a blockage in the intestine (paralytic ileus) or an acute form of colonic distension (toxic megacolon).

Country of origin

INDIA

Manufacturer/Marketer address

12, R. C. Patel Industrial Estate, Akota, Baroda - 390 020., INDIA
Other Info - ATR0063

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