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compositionComposition:ATROPINE-0.6MG
prescription
Prescription Medicine
info
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Atrotas Injection 1ml is used to treat bradycardia (decreased heart rate). It contains Atropine, which restores a normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ATROPINE-0.6MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Atrotas Injection 1ml

Atrotas Injection 1ml is a prescription injection used primarily to treat a dangerously slow heart rate and to reduce excessive secretions, such as saliva and mucus, in the airways before surgery. It also serves as an emergency treatment for certain types of poisoning. Because this medicine is usually given in a clinical or emergency setting, its use is carefully timed and managed by healthcare professionals.

This medication is typically injected directly into a vein, muscle, or under the skin as a single dose or repeated doses based on your clinical response. Since it is mostly used for short-term medical procedures or emergencies, there is no long-term schedule, but staying well-hydrated afterwards can help manage common side effects like dry mouth. Avoiding sudden physical exertion after receiving this injection is also highly recommended while your heart rate stabilises.

While highly effective, Atrotas Injection 1ml can cause common side effects such as a dry mouth, blurred vision, and a temporary increase in heart rate. Most of these symptoms wear off quickly, but you must contact a doctor immediately if you experience severe dizziness, extreme confusion, or eye pain.

Do not use this if you have specific health conditions, such as narrow-angle glaucoma, severe muscle weakness known as myasthenia gravis, or a severe blockage in your digestive or urinary tract. Talk to your doctor before receiving this medicine if you have a history of heart disease, high blood pressure, or an enlarged prostate.

Before receiving Atrotas Injection 1ml, inform your healthcare provider about all other medications you are taking, as certain drugs can increase the risk of side effects. It is also crucial to seek medical guidance if you are pregnant, breastfeeding, or an older adult, as your body may react differently to this treatment.

Uses of Atrotas Injection 1ml

Your doctor may prescribe this medicine to treat several conditions, including:

  • Slow heart rate (bradycardia): Atrotas Injection 1ml helps by increasing a dangerously slow heart rate back to a safe, normal level during medical emergencies.
  • Reducing body secretions: It helps dry up saliva and respiratory tract secretions before surgery, preventing blockages in the airway while you are under anaesthesia.
  • Treating certain poisonings: It acts as an antidote to reverse the dangerous effects of poisoning caused by specific insecticides or chemical agents.

Key Benefits

Atrotas Injection 1ml provides rapid and effective support in critical medical situations by helping restore essential body functions and maintain stability during emergencies and procedures. Key benefits include:

  • Supports Heart Rate Stabilisation: By helping restore a more normal heart rhythm or rate when required, Atrotas Injection 1ml supports effective blood circulation and helps ensure vital organs receive adequate oxygen.
  • Provides Rapid Emergency Support: In acute medical situations, Atrotas Injection 1ml acts quickly to help manage serious conditions where immediate stabilisation is needed.
  • Supports Safer Surgical Recovery: During medical procedures, Atrotas Injection 1ml helps maintain clearer airways by reducing excess fluid buildup in the lungs, lowering the risk of breathing difficulties associated with anaesthesia.
  • Improves Patient Stability: By supporting cardiovascular and respiratory function, Atrotas Injection 1ml helps promote a smoother recovery process in emergency and surgical settings.
Side effects of Atrotas Injection 1ml
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink enough water throughout the day.
  • Avoid alcohol and caffeine.
  • Take a bath or cool shower frequently.
  • Wear loose-fitted light-coloured clothing.
  • Use a hat to protect yourself from sunlight.
  • Avoid heavy activity or strenuous exercise in hot environments.
  • Consult the doctor if you notice significant decrease in sweating.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Atrotas Injection 1ml will be administered by a healthcare professional.
  • Do not self-administer.

How Atrotas Injection 1ml Works

Atrotas Injection 1ml works by blocking the action of acetylcholine, which is a natural chemical messenger in your body. Acetylcholine is responsible for sending signals that slow down the heart rate and increase secretions like saliva and sweat. By blocking these signals, Atrotas Injection 1ml allows your heart rate to increase and dries up excess fluids in your mouth and airways. It also relaxes the smooth muscles in your eyes and digestive tract, helping to stabilise your body's vital functions during surgery or emergency situations.
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Alcohol

Unsafe

Alcohol consumption may worsen the side effects of this medicine, such as dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atrotas Injection 1ml.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Atrotas Injection 1ml only if the benefits outweigh the risk.

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Breast Feeding

Caution

Please inform your doctor if you are breastfeeding. Your doctor will prescribe Atrotas Injection 1ml only if the benefits outweigh the risks.

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Driving

Unsafe

Atrotas Injection 1ml may cause side effects like dizziness and drowsiness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Consult your doctor

Consult your doctor if you have any history of liver diseases or hepatic impairment before receiving Atrotas Injection 1ml.

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Kidney

Consult your doctor

Consult your doctor if you have any history of kidney diseases/impairment before receiving Atrotas Injection 1ml.

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Children

Consult your doctor

Please consult your doctor. Your doctor will determine the dose based on your child's age and condition.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Caution

Atrotas Injection 1ml can be administered in elderly patients with extreme caution, if prescribed by the physician. Dosage adjustment may be needed.

What if I have taken an overdose of Atrotas Injection 1ml

If you receive too much of this medication, seek immediate emergency medical help. Symptoms of an overdose may include extreme dry mouth, severe blurred vision, confusion, rapid breathing, and a very fast heartbeat.

Diet & Lifestyle Advise

  • Stay hydrated: Sip water frequently, suck on ice chips, or use sugar-free hard candy to relieve dry mouth symptoms.
  • Protect your eyes: Wear sunglasses when outdoors or in brightly lit rooms, as your eyes may become highly sensitive to light.
  • Avoid overheating: This medication can reduce sweating, making it easier for your body to overheat. Avoid hot baths, saunas, and intense exercise in warm weather.
  • Prevent constipation: Eat fibre-rich foods and drink plenty of fluids if your treatment plan allows, to keep your bowel movements regular.
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Have a query?

How Soon It Starts Working

  • The time required for Atrotas Injection 1ml to start to work: The time required for Atrotas Injection 1ml to start to work is 1 hour after administration.
  • The time for which the effects of Atrotas Injection 1ml last: The effect of Atrotas Injection 1ml lasts for 4 hours.

What if you forget to take Atrotas Injection 1ml

Since Atrotas Injection 1ml is usually given by a healthcare professional in a clinical environment, it is highly unlikely that you will miss a dose. However, if you are on a self-treatment plan at home and miss a scheduled dose, contact your doctor or pharmacist immediately for instructions. Do not double the dose to make up for a missed one.

Storage

• SStore Atrotas Injection 1ml at controlled room temperature, typically between 20°C and 25°C (68°F and 77°F). • Keep the medication in its original packaging to protect it from direct light. Do not freeze this medication.

Drug Warnings

  • Check the injection before use: Inspect the liquid inside the vial or syringe before administration. It should be clear and colourless. Do not use it if you notice particles, cloudiness, or any change in colour.
  • Avoid activities requiring clear vision: Do not drive or operate heavy machinery after receiving this injection, as it may cause temporary blurred vision, dizziness, or reduced alertness.
  • Rotate injection sites: If you are administering this medicine at home, change the injection site each time to reduce the risk of skin irritation, discomfort, or tissue damage.
  • Dispose of injection equipment safely: Place used needles and syringes in a designated sharps container to prevent accidental needle-stick injuries.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Antihistamines and cold medicines: Taking these alongside Atrotas Injection 1ml can significantly increase side effects like dry mouth, blurred vision, and difficulty urinating.
  • Tricyclic antidepressants: Combining these can raise the risk of experiencing a rapid heart rate and severe constipation.
  • Certain medications for Parkinson's disease: Using these with Atrotas Injection 1ml can worsen side effects such as confusion and dry eyes.
AtropineZonisamide
Severe
AtropinePotassium chloride
Severe

Drug-Drug Interactions

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AtropineZonisamide
Severe
How does the drug interact with Atrotas Injection 1ml:
Coadministration of Atrotas Injection 1ml and Zonisamide can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atrotas Injection 1ml and Zonisamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropinePotassium chloride
Severe
How does the drug interact with Atrotas Injection 1ml:
Co-administration of Atrotas Injection 1ml with Potassium chloride oral tablets or capsules can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Atrotas Injection 1ml and Potassium chloride, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact the doctor right away: severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting(especially with blood), decreased hunger, dark, tarry stools. Do not discontinue any medications without a doctor's advice.
AtropineSolifenacin
Severe
How does the drug interact with Atrotas Injection 1ml:
When Atrotas Injection 1ml is used with solifenacin may cause side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems).

How to manage the interaction:
Co- administration of Atrotas Injection 1ml with solifenacin can lead to an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, reduced sweating, trouble urinating, abdominal cramps, constipation, irregular heartbeat, disorientation, and memory issues, consult the doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
AtropineHydromorphone
Severe
How does the drug interact with Atrotas Injection 1ml:
Using Hydromorphone together with Atrotas Injection 1ml may increase the risk and/or severity of some side effects (dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation).

How to manage the interaction:
Although taking Hydromorphone and Atrotas Injection 1ml together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: trouble peeing, feeling dizzy or sleepy, feeling confused or having trouble focusing, dry mouth, constipation, or feeling less mentally sharp. Do not discontinue any medications without consulting a doctor.
AtropineSecretin
Severe
How does the drug interact with Atrotas Injection 1ml:
When Secretin human is used with Atrotas Injection 1ml, the therapeutic efficacy of Secretin human can be decrease.

How to manage the interaction:
Although there is a possible interaction between Atrotas Injection 1ml and Secretin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtropinePotassium citrate
Severe
How does the drug interact with Atrotas Injection 1ml:
Taking potassium citrate oral tablets or capsules with Atrotas Injection 1ml may increase the irritating effects of potassium on stomach and upper intestine.

How to manage the interaction:
Taking Atrotas Injection 1ml with potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtropineTopiramate
Severe
How does the drug interact with Atrotas Injection 1ml:
When Atrotas Injection 1ml and Topiramate are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atrotas Injection 1ml and topiramate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropinePramlintide
Severe
How does the drug interact with Atrotas Injection 1ml:
Coadministration of Pramlintide with Atrotas Injection 1ml can increase the risk of reduced movement in the digestive system.

How to manage the interaction:
Taking Atrotas Injection 1ml with Pramlintide together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
AtropineUmeclidinium bromide
Severe
How does the drug interact with Atrotas Injection 1ml:
Using Atrotas Injection 1ml together with umeclidinium may increase side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes).

How to manage the interaction:
Although taking Atrotas Injection 1ml and Umeclidinium bromide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Atrotas Injection 1ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANTICHOLINERGICS]

FAQs

Atrotas Injection 1ml belongs to a class of drugs known as anticholinergics, which are used to treat bradycardia (a decreased heart rate). It restores a normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.
Atrotas Injection 1ml contains Atropine, which is used to treat bradycardia (slow heart rate). It works by blocking the activity of acetylcholine (a chemical messenger). As a result, this helps to bring the blood pressure back within the normal range and relaxes the heart.
Atropine may decrease sweating and increase your risk of heat stroke. Hence, it is advisable to avoid becoming overheated or dehydrated during any physical activity, especially in hot weather.
Atropine is contraindicated in allergic reactions, urinary difficulties, elevated pressure in the eye (glaucoma), and stomach-related disorders like achalasia of the oesophagus, a blockage in the intestine (paralytic ileus) or an acute form of colonic distension (toxic megacolon).
When injected into a vein, Atrotas Injection 1ml begins to work almost immediately, often within a couple of minutes. When injected into a muscle, it may take about 15 to 30 minutes to feel its full effects. Talk to your doctor if you have questions about your specific treatment response.
Yes, temporary blurred vision is a very common effect of this medicine because it relaxes the muscles in your eyes and dilates your pupils. This effect will wear off gradually, but you should avoid driving until your vision returns to normal. Talk to your doctor if your vision does not improve.
This medication should only be used during pregnancy if the potential benefits outweigh the risks to the unborn baby. Your doctor will carefully evaluate your situation before injecting this medicine. Talk to your doctor if you are pregnant or planning to become pregnant.
In most cases, this medication is given in a hospital or clinical setting by healthcare professionals. If your doctor prescribes it for home use, they will provide comprehensive training on how to safely inject it. Talk to your doctor or pharmacist to ensure you understand the correct technique.
Yes, by changing your heart rate, this medicine can temporarily affect your blood pressure. Your healthcare team will monitor your blood pressure and heart rate closely while you receive this medication. Talk to your doctor if you have concerns about your blood pressure history.
You should avoid alcohol while using this medicine, as alcohol can worsen side effects like dizziness, drowsiness, and blurred vision. Talk to your doctor or pharmacist about safe choices while undergoing treatment.
If you experience sudden, severe eye pain or changes in your vision, seek immediate medical care. This could be a sign of increased pressure in your eyes, which requires urgent evaluation. Talk to your doctor right away if you experience these symptoms.
Atrotas Injection 1ml blocks the action of acetylcholine, which reduces the activity of the salivary glands and decreases saliva production. This can cause dry mouth. Drinking water regularly, limiting caffeine, avoiding alcohol-containing mouthwashes, and chewing sugar-free gum or sugar-free candy may help relieve dryness. Consult your doctor if the symptom becomes severe or persistent.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.3695 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Atropine Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 212319S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Electronic Medicines Compendium (EMC). Pil.5000 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  5. U.S. Food and Drug Administration (FDA). 209260S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  6. Atropine [EMC Label]. 2016. [Accessed on 28 Mar. 2019]Check here
  7. Atropine Sulfate Ophthalmic Solution [Prescribing Information]. 2014. [Accessed on 20 Feb. 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ATR0087
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