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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Axepine 15 mg Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.

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Composition :

ARIPIPRAZOLE-15MG

Manufacturer/Marketer :

Cnx Health Care Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Axepine 15 mg Tablet

 Axepine 15 mg Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Axepine 15 mg Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterised by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Axepine 15 mg Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Axepine 15 mg Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Axepine 15 mg Tablet improves mood swings, depression, and other psychotic problems. 

Take Axepine 15 mg Tablet as prescribed. Your doctor will advise you on how often to take Axepine 15 mg Tablet , based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine 15 mg Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Axepine 15 mg Tablet or any other medicines, please tell your doctor. Axepine 15 mg Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions, including dizziness, difficulty moving and maintaining balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Axepine 15 mg Tablet if you are pregnant or breastfeeding, and consult a doctor. Axepine 15 mg Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Axepine 15 mg Tablet , please get in touch with a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine 15 mg Tablet .

Uses of Axepine 15 mg Tablet

Axepine 15 mg Tablet is primarily used in the treatment of schizophrenia. Its specific uses are as follows:<br/> • Schizophrenia: Axepine 15 mg Tablet is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.<br/> • Bipolar I Disorder (Manic Depression): Axepine 15 mg Tablet is used alone or in combination with mood stabilizers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilize mood and reduce irritability and hyperactivity.<br/> • Major Depressive Disorder (MDD) - As Adjunctive Therapy: Axepine 15 mg Tablet is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.<br/> • Tourette Syndrome (TS): Axepine 15 mg Tablet is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.<br/> • Autism Spectrum Disorder (ASD): Axepine 15 mg Tablet is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.<br/> • Maintenance Treatment: Axepine 15 mg Tablet is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.<br/>

Directions for Use

  • Axepine 15 mg Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Axepine 15 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Axepine 15 mg Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Axepine 15 mg Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Axepine 15 mg Tablet improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities. Axepine 15 mg Tablet may be used in combination with other medicines to treat depression. Additionally, Axepine 15 mg Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

How Axepine 15 mg Tablet Works

Axepine 15 mg Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Axepine 15 mg Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Axepine 15 mg Tablet improves mood swings, depression, and other psychotic problems.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Axepine 15 mg Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

What if I have taken an overdose of Axepine 15 mg Tablet

Do not take more than the prescribed dose of Axepine 15 mg Tablet , as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Axepine 15 mg Tablet or any other medicines, please tell your doctor. Axepine 15 mg Tablet should be used with caution in elderly patients above 65 years of age, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Axepine 15 mg Tablet if you are pregnant or breastfeeding, and consult a doctor. Axepine 15 mg Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Axepine 15 mg Tablet , please get in touch with a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking Axepine 15 mg Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine 15 mg Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Axepine 15 mg Tablet:
Co-administration of Metoclopramide with Axepine 15 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Axepine 15 mg Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Axepine 15 mg Tablet:
Taking rifabutin with Axepine 15 mg Tablet can reduce the blood levels of Axepine 15 mg Tablet.

How to manage the interaction:
Although taking Axepine 15 mg Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
AripiprazoleMethadone
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleMitotane
Severe
How does the drug interact with Axepine 15 mg Tablet:
When Axepine 15 mg Tablet and Mitotane are taken together, may decrease the blood levels of Axepine 15 mg Tablet, which may make Axepine 15 mg Tablet less effective in treating your condition

How to manage the interaction:
There may be a possibility of interaction between Axepine 15 mg Tablet and Mitotane, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazoleRifapentine
Severe
How does the drug interact with Axepine 15 mg Tablet:
Coadministration of Rifapentine may significantly reduce the blood levels of Axepine 15 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Axepine 15 mg Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any unusual symptoms, it's important to let a doctor know. Do not stop using any medications without talking to a doctor.
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Nalbuphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Axepine 15 mg Tablet with Nalbuphine can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleOxycodone
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleSodium oxybate
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using sodium oxybate together with Axepine 15 mg Tablet may increase side effects.

How to manage the interaction:
Taking Axepine 15 mg Tablet with Sodium oxybate together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and be aware of any changes. If you notice any of these signs - feeling tired, dizzy, lighthead ed, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Axepine 15 mg Tablet:
Taking bupropion with Axepine 15 mg Tablet may raise the chance of seizures (fits), which can happen with either medicine. Furthermore, bupropion can raise Axepine 15 mg Tablet levels in the blood, which may increase other side effects.

How to manage the interaction:
Co-administration of bupropion along with Axepine 15 mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AripiprazoleEsketamine
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Esketamine together with Axepine 15 mg Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Axepine 15 mg Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
  • Cut down sugars, salt, and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Engage in regular exercise and maintain a stable weight, as Axepine 15 mg Tablet may contribute to weight gain.
  • Avoid alcohol consumption, as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Axepine 15 mg Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Axepine 15 mg Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Axepine 15 mg Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Axepine 15 mg Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Axepine 15 mg Tablet .

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Liver

Caution

Take Axepine 15 mg Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Axepine 15 mg Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Axepine 15 mg Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Axepine 15 mg Tablet to children.

Have a query?

FAQs

Axepine 15 mg Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.

Axepine 15 mg Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Axepine 15 mg Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Axepine 15 mg Tablet improves behaviour, thoughts, and helps in having a better social life, enabling one to comfortably perform daily activities.

No, you are not recommended to take Axepine 15 mg Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Axepine 15 mg Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Axepine 15 mg Tablet with other medicines.

Axepine 15 mg Tablet may cause weight gain in some patients, but it is not a necessary side effect for everyone taking Axepine 15 mg Tablet . However, to avoid gaining weight while taking Axepine 15 mg Tablet , it is advisable to engage in regular exercise and limit high-calorie drinks. Instead, opt for non-alcoholic beverages, herbal tea, and lemon water.

Axepine 15 mg Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Axepine 15 mg Tablet .

Yes, Axepine 15 mg Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Axepine 15 mg Tablet and inform your doctor if you have diabetes before taking Axepine 15 mg Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.

No, you are not recommended to stop taking Axepine 15 mg Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Axepine 15 mg Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Axepine 15 mg Tablet , please consult your doctor so that the dose can be gradually reduced.

Yes, Axepine 15 mg Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.

Axepine 15 mg Tablet might start working within a few days or weeks. However, you may notice the full benefits of Axepine 15 mg Tablet after 2-3 months. Continue taking Axepine 15 mg Tablet for the prescribed duration to prevent the recurrence of symptoms.

Axepine 15 mg Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

Elderly patients more than 65 years old with dementia-related psychosis treated with Axepine 15 mg Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Axepine 15 mg Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.

Avoid intake of grapefruit juice with Axepine 15 mg Tablet as it may reduce the effect of Axepine 15 mg Tablet . Also, avoid alcohol consumption with Axepine 15 mg Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Axepine 15 mg Tablet .

Consult the doctor if you are diabetic, as Axepine 15 mg Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.

Axepine 15 mg Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine 15 mg Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

1 A, PATANWALA INDUSTRTIAL COMPOUND, LBS ROAD, NEAR SHREYAS CINEMA, GHATKOPAR-W, MUMBAI-400 086
Other Info - AXE0231

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