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compositionComposition:ARIPIPRAZOLE-5MG
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Prescription Medicine
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Axepine MD 5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ARIPIPRAZOLE-5MG

Manufacturer/Marketer :

Cnx Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Axepine MD 5 Tablet

Axepine MD 5 Tablet is an oral prescription medicine used to treat conditions that affect how you think, feel, or behave. Doctors commonly prescribe it to help manage schizophrenia, bipolar disorder, and major depression. It works by balancing certain chemical messengers in the brain to improve mood, thoughts, and behaviour.

For this medicine to work effectively, it is important to take it consistently every single day at the same time. You can take it with or without food. Along with taking your medicine, maintaining a stable daily routine, eating a balanced diet, and getting regular sleep can help you achieve the best results.

While taking Axepine MD 5 Tablet , some people may experience mild side effects like drowsiness, headache, or nausea. However, you must contact your doctor immediately if you notice more serious signs, such as uncontrollable muscle movements, severe stiffness, a high fever, or sudden changes in your mood.

Do not take this if you have had a severe allergic reaction to it in the past. Elderly patients with dementia-related psychosis should not take this medicine due to serious health risks. Before starting, tell your doctor if you have a history of heart problems, diabetes, seizures, or a low white blood cell count.

This medicine can interact with alcohol, smoking, and other drugs, such as certain blood pressure medicines or anti-seizure drugs, which can change how it works or increase side effects. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this medicine is safe for you.

Uses of Axepine MD 5 Tablet

Axepine MD 5 Tablet is used to manage schizophrenia, bipolar disorder, and major depression. The detailed uses of Axepine MD 5 Tablet are as follows:

  • Schizophrenia: Axepine MD 5 Tablet helps reduce symptoms like hearing voices, seeing things that are not there (hallucinations), and feeling unusually suspicious of others.
  • Bipolar I Disorder: It helps control manic episodes, which are periods of extreme excitement, overactivity, irritability, and racing thoughts.
  • Major Depressive Disorder: It is used as an add-on treatment alongside standard antidepressants when those medicines do not fully relieve your symptoms.
  • Irritability associated with autistic disorder: It helps manage severe mood swings, temper tantrums and self-injurious behaviours in children and teenagers.
  • Tourette's disorder: It helps reduce the frequency and severity of uncontrollable physical movements and vocal sounds (tics).
     

Key Benefits

Axepine MD 5 Tablet helps improve mental health by balancing chemical messengers in the brain and supporting emotional stability. It can help manage symptoms of certain mental health conditions, improving daily functioning and overall quality of life.

  • Helps Improve Mood and Emotional Wellbeing: By restoring the balance of brain chemicals, Axepine MD 5 Tablet helps reduce symptoms such as persistent sadness, anxiety, irritability, and emotional distress, supporting a more stable mood.
  • Supports Control of Mood Swings: For individuals with conditions involving significant mood fluctuations, Axepine MD 5 Tablet helps reduce the frequency and severity of extreme mood changes, promoting greater emotional stability and day-to-day functioning.
  • Enhances Daily Functioning: By improving mood, reducing anxiety, and supporting clearer thinking, Axepine MD 5 Tablet helps individuals participate more comfortably in work, social interactions, and everyday activities. When used as an add-on treatment for depression, it may provide additional symptom relief when antidepressant therapy alone is not sufficient.
     
Side effects of Axepine MD 5 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Directions for Use

  • Axepine MD 5 Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Axepine MD 5 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Axepine MD 5 Tablet Works

Axepine MD 5 Tablet works by acting on specific chemical messengers in your brain, primarily dopamine and serotonin. These chemicals play a vital role in regulating your mood, thoughts, and behaviours. Unlike some older medicines that completely block these chemicals, Axepine MD 5 Tablet acts like a thermostat. If the levels of dopamine in certain parts of the brain are too high, it helps lower them. If the levels are too low, it helps boost them. This stabilising effect helps reduce hallucinations, calm hyperactive states, and improve overall mood and motivation.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Axepine MD 5 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Axepine MD 5 Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Axepine MD 5 Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Axepine MD 5 Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Axepine MD 5 Tablet .

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Liver

Caution

Take Axepine MD 5 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Axepine MD 5 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Axepine MD 5 Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Axepine MD 5 Tablet to children.

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Heart

Caution

Exercise caution while taking Axepine MD 5 Tablet if you have any cardiac problems due to the risk of hypotension and irregular heartbeat.

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Geriatrics

Consult your doctor

Limited information available for use of Axepine MD 5 Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Axepine MD 5 Tablet

If you take too much of this medicine, seek immediate medical attention or call your local poison control centre. Symptoms of an overdose may include severe sleepiness, a fast heart rate, vomiting, and tremors.

Diet & Lifestyle Advise

  • Stay hydrated: This medicine can make it harder for your body to cool down. Drink plenty of water and avoid becoming overheated, especially during hot weather or intense exercise.
  • Monitor your weight and blood sugar: Eat a balanced diet rich in vegetables, lean proteins, and whole grains to help manage potential weight gain and blood sugar changes.
  • Avoid alcohol: Drinking alcohol can worsen side effects like sleepiness, dizziness, and confusion.
  • Stand up slowly: To prevent dizziness or fainting, take your time when rising from a sitting or lying position.
     
health query

Have a query?

How Soon It Starts Working

  • The time required for Axepine MD 5 Tablet to start to work: The time required for Axepine MD 5 Tablet to show its action is not clinically established.
  • The time for which the effects of Axepine MD 5 Tablet last: The duration of action for Axepine MD 5 Tablet is not clinically established.

What if you forget to take Axepine MD 5 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Axepine MD 5 Tablet tablets at room temperature, between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Pay close attention to any sudden changes in mood, behaviour, or thoughts of self-harm, especially during the first few weeks of starting this medicine.
  • Avoid driving, operating machinery, or performing dangerous tasks until you know how this medicine affects your alertness.
  • Tell your dentist or surgeon that you are taking Axepine MD 5 Tablet before undergoing any medical procedures.
  • Avoid hot tubs, saunas, and prolonged exposure to direct sunlight, as this medicine can affect your body's temperature regulation.
  • If you have diabetes, check your blood sugar levels regularly, as this medicine can cause blood sugar levels to rise.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood pressure medicines: Combining Axepine MD 5 Tablet with drugs that lower blood pressure may increase the risk of dizziness or fainting when standing up.
  • Sedatives and sleep aids: Taking this medicine with other drugs that cause drowsiness, such as allergy medicines, sleep aids, or strong pain relievers, can cause severe sleepiness.
  • Liver enzyme inhibitors or inducers: Certain antifungals (like ketoconazole) or antidepressants (like fluoxetine) can raise levels of Axepine MD 5 Tablet in your body, while some anti-seizure medicines (like carbamazepine) can lower them. Your doctor may need to adjust your dose.


Drug-Food Interactions

  • Grapefruit: Grapefruit and grapefruit juice may interfere with how your body processes this medicine, potentially increasing side effects.


Drug-Disease Interactions

  • Dementia: Elderly patients with dementia-related psychosis must not take this medicine, as it increases the risk of stroke and death.
  • Seizure disorders: Use with caution if you have a history of seizures, as this medicine may increase the likelihood of having one.
  • Diabetes: This medicine can raise blood sugar levels, requiring close monitoring if you have diabetes or a family history of the condition.
     
AripiprazoleMetoclopramide
Critical
AripiprazoleAlfentanil
Severe

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
How does the drug interact with Axepine MD 5 Tablet:
Co-administration of Metoclopramide with Axepine MD 5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Axepine MD 5 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleAlfentanil
Severe
How does the drug interact with Axepine MD 5 Tablet:
Using Axepine MD 5 Tablet together with Alfentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine MD 5 Tablet and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleDezocine
Severe
How does the drug interact with Axepine MD 5 Tablet:
Using Axepine MD 5 Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine MD 5 Tablet with Dezocine together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
AripiprazolePhenytoin
Severe
How does the drug interact with Axepine MD 5 Tablet:
Phenytoin may decrease the blood levels of Axepine MD 5 Tablet, which may make Axepine MD 5 Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Phenytoin and Axepine MD 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
AripiprazoleButorphanol
Severe
How does the drug interact with Axepine MD 5 Tablet:
Using Axepine MD 5 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine MD 5 Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleEnzalutamide
Severe
How does the drug interact with Axepine MD 5 Tablet:
When Axepine MD 5 Tablet is taken with Enzalutamide, the amount of Axepine MD 5 Tablet in the blood may decrease. This might reduce Axepine MD 5 Tablet's ability to effectively treat disease.

How to manage the interaction:
Although there is a possible interaction between Enzalutamide and Axepine MD 5 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazoleMetrizamide
Severe
How does the drug interact with Axepine MD 5 Tablet:
Coadministration of Axepine MD 5 Tablet and Metrizamide may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Axepine MD 5 Tablet and Metrizamide together can cause an interaction, it can be taken if a doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not discontinue any medications without consulting a doctor.
AripiprazoleMethadone
Severe
How does the drug interact with Axepine MD 5 Tablet:
Using Axepine MD 5 Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine MD 5 Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazolePentazocine
Severe
How does the drug interact with Axepine MD 5 Tablet:
Using Axepine MD 5 Tablet together with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine MD 5 Tablet and Pentazocine together can cause an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
AripiprazolePhenobarbital
Severe
How does the drug interact with Axepine MD 5 Tablet:
Phenobarbital can considerably lower Axepine MD 5 Tablet levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Axepine MD 5 Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Axepine MD 5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.
Axepine MD 5 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Axepine MD 5 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Axepine MD 5 Tablet improves behaviour and thoughts, enhances social life, and helps one comfortably perform daily activities.
No, you are not recommended to take Axepine MD 5 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Axepine MD 5 Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Axepine MD 5 Tablet with other medicines.
Axepine MD 5 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Axepine MD 5 Tablet .
Yes, Axepine MD 5 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Axepine MD 5 Tablet , and you should inform your doctor if you have diabetes before starting Axepine MD 5 Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.
No, you are not recommended to stop taking Axepine MD 5 Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Axepine MD 5 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Axepine MD 5 Tablet , please consult your doctor so that the dose can be gradually reduced.
Yes, Axepine MD 5 Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.
Axepine MD 5 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.
Elderly patients more than 65 years old with dementia-related psychosis treated with Axepine MD 5 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Axepine MD 5 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.
Avoid intake of grapefruit juice with Axepine MD 5 Tablet as it may reduce the effect of Axepine MD 5 Tablet . Also, avoid alcohol consumption with Axepine MD 5 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Axepine MD 5 Tablet .
Consult the doctor if you are diabetic, as Axepine MD 5 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.
Axepine MD 5 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine MD 5 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.
Some people may experience weight gain while taking this medicine. Regular exercise and a balanced diet can help manage this. Talk to your doctor if you are concerned about weight changes.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of other side effects. Talk to your doctor if you have questions.
This depends on how the medicine affects you. If it makes you feel sleepy, your doctor may suggest taking it at bedtime. If it makes you feel restless or alert, taking it in the morning may be better. Talk to your doctor for advice.
Taking this medicine during the third trimester of pregnancy may cause side effects in the newborn baby. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the risks and benefits.
An inability to sit still or a feeling of inner restlessness can sometimes occur. Do not stop the medicine; instead, talk to your doctor, who may adjust your dose or suggest a way to manage this.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1 A, PATANWALA INDUSTRTIAL COMPOUND, LBS ROAD, NEAR SHREYAS CINEMA, GHATKOPAR-W, MUMBAI-400 086
Other Info - AXE0172

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