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compositionComposition:AXITINIB-5MG
prescription
Prescription Medicine
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₹1484 with coupons & bank offers*

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Axzyb 5 Tablet 14's is used to treat Renal Cell Carcinoma. It contains Axitinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Axzyb 5 Tablet 14's stops the production, spread and growth of cancerous cells.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AXITINIB-5MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Axzyb 5 Tablet 14's

Axzyb 5 Tablet 14's is a targeted anticancer medicine used to treat advanced kidney cancer (renal cell carcinoma). It works by blocking proteins involved in the formation of new blood vessels that supply tumours, helping to slow or stop cancer growth and spread. This medicine is commonly prescribed alone or in combination with other anticancer therapies to improve disease control in patients with advanced renal cell carcinoma.

You will typically take Axzyb 5 Tablet 14's twice daily, approximately 12 hours apart. You can take this medication with or without food, but it is important to take it consistently at the same times each day. To support your body during treatment, your doctor may suggest making simple lifestyle changes, such as eating a low-sodium diet and staying well-hydrated to help manage potential side effects.

While taking Axzyb 5 Tablet 14's, you may experience common side effects like diarrhoea, high blood pressure, and feeling unusually tired. If you experience severe side effects, such as sudden chest pain, unusual bleeding, or severe abdominal pain, you must contact your healthcare provider immediately.

Do not take this if you have uncontrolled high blood pressure or are allergic to any of its ingredients. Before starting this treatment, talk to your doctor if you have a history of blood clots, heart problems, liver damage, bleeding issues, or thyroid conditions.

Certain medications, as well as smoking and drinking alcohol, can change how Axzyb 5 Tablet 14's works in your body. It is vital to consult your doctor if you are pregnant, breastfeeding, or planning a family, as this medication can harm an unborn baby. Elderly individuals should also talk to their doctor to ensure this medication is safe for them.

Uses of Axzyb 5 Tablet 14's

Axzyb 5 Tablet 14's is used to treat advanced kidney cancer (renal cell carcinoma).. The detailed uses of Axzyb 5 Tablet 14's are as follows:

  • Advanced Kidney Cancer: Axzyb 5 Tablet 14's is used to treat advanced renal cell carcinoma (kidney cancer) that has spread to other parts of the body, particularly after other initial treatments have stopped working.

Key Benefits

Axzyb 5 Tablet 14's helps treat advanced kidney cancer by slowing the growth and spread of cancer cells. With regular use as prescribed, it helps control disease progression, reduce tumour-related symptoms, and support better long-term treatment outcomes.

  • Helps Slow Cancer Progression: By targeting pathways that promote cancer cell growth, this medicine helps delay the progression of advanced kidney cancer and supports effective disease control.
  • Reduces Tumour-Related Symptoms: By slowing the growth or shrinking tumours, this medicine may help relieve pain, pressure, and other symptoms caused by cancer, improving overall comfort.
  • Supports Quality of Life: Effective disease control helps maintain energy levels, improve daily functioning, and allows many patients to continue their regular activities with greater comfort during treatment.

Directions for Use

  • Axzyb 5 Tablet 14's can be taken with or without food as prescribed by your doctor.
  • It is recommended to take twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush Axzyb 5 Tablet 14's.

How Axzyb 5 Tablet 14's Works

Axzyb 5 Tablet 14's contains axitinib, which belongs to a group of medicines known as targeted therapies. It works by blocking specific proteins on the surface of cells that control the growth of blood vessels. Tumours need a constant blood supply to grow and spread throughout the body. By blocking these proteins, Axzyb 5 Tablet 14's helps cut off the blood supply to the kidney cancer cells, essentially starving them of the oxygen and nutrients they need to multiply.
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Alcohol

Caution

Limit alcohol consumption while taking Axzyb 5 Tablet 14's.

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Pregnancy

Unsafe

Axzyb 5 Tablet 14's is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Axzyb 5 Tablet 14's. You should not become pregnant while you are taking Axzyb 5 Tablet 14's. Using effective birth control methods while on treatment with Axzyb 5 Tablet 14's is suggested.

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Breast Feeding

Caution

It is not known whether Axzyb 5 Tablet 14's passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before taking Axzyb 5 Tablet 14's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Axzyb 5 Tablet 14's may cause dizziness and visual disturbances in some patients. Hence, do not drive, operate machinery, or engage in any activity that needs clear vision until you are confident that you can do so safely while you are on treatment with Axzyb 5 Tablet 14's.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Axzyb 5 Tablet 14's is known to cause elevated liver enzymes, which may be fatal. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Axzyb 5 Tablet 14's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Axzyb 5 Tablet 14's is not recommended for use in children below 18 years of age as the safety and efficacy is not established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Axzyb 5 Tablet 14's.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Axzyb 5 Tablet 14's to geriatric patients. Your doctor will prescribe Axzyb 5 Tablet 14's if the benefits outweigh the risks.

What if I have taken an overdose of Axzyb 5 Tablet 14's

If you take too much of this medicine, seek immediate medical attention or contact a nearby hospital. Do not wait for symptoms of an overdose to appear.

Diet & Lifestyle Advise

  • Monitor your blood pressure daily and keep a log to share with your healthcare provider, as this medication commonly raises blood pressure.
  • Protect your hands and feet by wearing comfortable, well-fitting shoes and applying thick moisturising creams to prevent peeling or soreness.
  • Stay well-hydrated throughout the day by drinking plenty of water, which helps manage and prevent dehydration from diarrhoea.
  • Avoid eating grapefruit or drinking grapefruit juice, as these can increase the level of the drug in your body to unsafe levels.
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How Soon It Starts Working

The time required for Axzyb 5 Tablet 14's to start to work: The time required for Axzyb 5 Tablet 14's to show its action is not clinically established. The time for which the effects of Axzyb 5 Tablet 14's last: The duration of action for Axzyb 5 Tablet 14's is not clinically established.

What if you forget to take Axzyb 5 Tablet 14's

If you miss a dose of Axzyb 5 Tablet 14's, skip the missed dose and take your next dose at your regularly scheduled time. Do not take two doses at the same time to make up for a missed one. If you vomit after taking a dose, do not take an extra tablet; simply wait and take your next scheduled dose at the normal time.

Storage

• Store Axzyb 5 Tablet 14's tablets at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect your tablets before taking them; do not take any tablet that is broken, chipped, or damp.
  • Make sure your doctor knows you are taking Axzyb 5 Tablet 14's before scheduling any surgery or dental procedures, as you may need to temporarily stop taking this medicine to allow wounds to heal properly.
  • Get your thyroid function checked regularly with blood tests, as this medicine can affect your thyroid hormone levels.
  • Keep a written record of your daily blood pressure readings so your doctor can adjust your blood pressure medications if necessary.

verifiedApollotooltip

  • Strong CYP3A4/5 inhibitors: Taking these medications (such as certain antibiotics or antifungals) alongside Axzyb 5 Tablet 14's can raise the amount of the drug in your body, increasing the risk of serious side effects.
  • Strong CYP3A4/5 inducers: Taking these medications (such as certain seizure medicines or tuberculosis treatments) can decrease the amount of Axzyb 5 Tablet 14's in your blood, making the treatment less effective.

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verifiedApollotooltip
  • Grapefruit and grapefruit juice: May increase the risk of severe side effects by slowing down how your body breaks down the medication.
  • Smoking tobacco: Can decrease the amount of the medication in your body, which may reduce how well the drug works.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

No. Axzyb 5 Tablet 14's should not be used during pregnancy because it can seriously harm an unborn baby. It is also not recommended while breastfeeding. Do not take Axzyb 5 Tablet 14's if you are allergic to axitinib or any of its ingredients. Use effective contraception during treatment and for the period recommended by your doctor. If you are pregnant, planning a pregnancy, or think you may be pregnant, contact your doctor immediately.
Yes, you can take Axzyb 5 Tablet 14's with or without food. Try to be consistent with how you take it each day. Talk to your doctor or pharmacist if you need help planning your schedule.
If you throw up after taking your dose, do not take an extra dose. Simply wait and take your next dose at your regular scheduled time. Talk to your doctor or pharmacist if vomiting continues.
Some people may experience hair thinning or hair loss while taking Axzyb 5 Tablet 14's, though this is usually temporary. Talk to your doctor if you are concerned about hair changes.
While there is no direct interaction, alcohol can worsen side effects like dehydration, dizziness, and liver strain. Talk to your doctor or pharmacist before drinking alcohol during your treatment.
You should check your blood pressure regularly, often daily, especially during the first few weeks of starting Axzyb 5 Tablet 14's. Talk to your doctor if your blood pressure begins to rise.
Axzyb 5 Tablet 14's can interfere with how your body heals wounds. You may need to stop taking it before and after a planned surgery or dental work. Talk to your doctor for specific instructions.
No, Axzyb 5 Tablet 14's is a targeted therapy rather than traditional chemotherapy. It specifically blocks the signals and blood supply that cancer cells need to grow, rather than killing all fast-growing cells. Talk to your doctor for more details.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - AXZ0007
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