Azadine-O Tablet 14's belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.
Azadine-O Tablet 14's contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
In some cases, Azadine-O Tablet 14's may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Do not use Azadine-O Tablet 14's if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azadine-O Tablet 14's. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Azadine-O Tablet 14's
Acute myeloid leukaemia
Azadine-O Tablet 14's belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. Azadine-O Tablet 14's contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
Directions for Use
Take Azadine-O Tablet 14's with or without food. Swallow the medicine as a whole with water; do not crush or chew it.
Store in a cool and dry place away from sunlight
Side Effects of Azadine-O Tablet 14's
Arthralgia (joint pain)
Do not take Azadine-O Tablet 14's if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.
Drug-Drug Interactions: No interactions found/established.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: No interactions found/established.
Diet & Lifestyle Advise
Eat a healthy diet and exercise regularly as it helps maintain proper weight.
Avoid smoking and alcohol consumption.
Include vegetables and fruits in your diet.
Avoid fast food, fried food, processed meats, refined carbs and added sugar.
Get optimal sleep; rest well.
Drink enough water and eat fibre-rich foods, vegetables and fruits.
If you are a female, you should take a pregnancy test prior to the start of the treatment. Use reliable contraception to prevent pregnancy during treatment and for 6 months after the last dose.
Male patients with partners of reproductive potential should use effective contraception during treatment and for 3 months after stopping the treatment.
If the powder from the medicine comes in contact with your skin, wash the area well with soap and water immediately.
If the powder from the medicine comes in contact with mucous membranes (eyes or mouth), flush the area with water immediately.
Acute myeloid leukaemia: Acute myeloid leukaemia, also called acute myelogenous leukaemia or acute nonlymphocytic leukaemia, is the cancer of blood and bone marrow with excess immature white blood cells. Symptoms include fever, recurrent infections, fatigue, and easy bruising.
Consult your doctor
It is not known if alcohol affects Azadine-O Tablet 14's. Please consult your doctor.
Azadine-O Tablet 14's can harm the unborn baby. Avoid becoming pregnant during treatment with Azadine-O Tablet 14's. Consult the doctor immediately if you become pregnant during treatment with Azadine-O Tablet 14's.
Avoid breastfeeding during treatment with Azadine-O Tablet 14's and for one week after the last dose.
Consult your doctor
It is unknown if Azadine-O Tablet 14's affects your ability to drive. Drive only if you are alert.
If you have a history of liver disease, inform your doctor before taking Azadine-O Tablet 14's.
If you have a history of kidney disease, inform your doctor before taking Azadine-O Tablet 14's.
Azadine-O Tablet 14's is not recommended for children below 18 years as safety and effectiveness have not been established.
How does Azadine-O Tablet 14's work?
Azadine-O Tablet 14's works by helping bone marrow in the production of normal blood cells and killing abnormal cells in the bone marrow.
Does Azadine-O Tablet 14's affect fertility?
Azadine-O Tablet 14's may affect fertility in men and women. Consult the doctor if you have any concerns.
Why has the doctor prescribed anti-nausea medicine with Azadine-O Tablet 14's?
The doctor will prescribe anti-nausea medicine to help prevent nausea and vomiting during treatment with Azadine-O Tablet 14's. Take the anti-nausea medicine 30 minutes before each dose of Azadine-O Tablet 14's or as the doctor advises.
What if I vomit after taking Azadine-O Tablet 14's?
If you vomit after taking a dose Azadine-O Tablet 14's, avoid taking another dose on the same day. Take the next dose at the regular time the next day. Talk to the doctor if you have any concerns.
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Country of origin
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.