Azathioprine-50 Tablet 10's
MRP ₹106
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₹15.9 Cashback (15%)
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Genuine Products
Composition :
AZATHIOPRINE-50MG
Manufacturer/Marketer :
Care Formulations Lab
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
NPPA :
Regulated
About Azathioprine-50 Tablet
Azathioprine-50 Tablet is used to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn's disease and ulcerative colitis for patients who have undergone a kidney transplant.
Azathioprine-50 Tablet contains 'Azathioprine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azathioprine-50 Tablet helps stop your body from rejecting a new organ by suppressing your immune system.
In some cases, you may experience certain common side effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, loss of appetite, increased liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Take Azathioprine-50 Tablet as prescribed. Your doctor will advise you on how often you should take Azathioprine-50 Tablet based on your medical condition. Azathioprine-50 Tablet can be taken with or without food. Do not crush, chew, or break it.
Do not take Azathioprine-50 Tablet if you are pregnant or planning a pregnancy. Azathioprine-50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Azathioprine-50 Tablet should not be given to children as safety and efficacy have not been established. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Uses of Azathioprine-50 Tablet
Azathioprine-50 Tablet is used to manage autoimmune and inflammatory conditions by suppressing the immune system. The detailed uses of Azathioprine-50 Tablet are as follows:
- Rheumatoid arthritis: Azathioprine-50 Tablet reduces joint pain, swelling, and stiffness in individuals with active rheumatoid arthritis.
- Autoimmune hepatitis: Azathioprine-50 Tablet helps to manage liver inflammation caused by the immune system.
- Prevention of kidney transplant rejection: Azathioprine-50 Tablet suppresses immunological activity, preventing the body from rejecting a transplanted kidney.
- Systemic lupus erythematosus:Azathioprine-50 Tablet treats symptoms that affect the skin, joints, and internal organs.
- Blood disorders: Azathioprine-50 Tablet treats thrombocytopenia and hemolytic anemia.
- Autoimmune skin and muscle diseases: Azathioprine-50 Tablet treats pemphigus and dermatomyositis by reducing skin blisters, sores, and muscle inflammation.
- Vasculitis: Azathioprine-50 Tablet treats blood vessel inflammation in conditions such as polyarteritis nodosa.
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Directions for Use
- Azathioprine-50 Tablet can be taken with or without food. However, if you experience stomach upset, take it with food. Avoid taking it with milk or dairy products, as they may reduce its effectiveness.
- Your doctor will determine the dosage and timing of this medication based on your medical condition. If taken regularly, it is typically recommended 1-2 times daily.
- Swallow Azathioprine-50 Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Azathioprine-50 Tablet helps to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys.
- Azathioprine-50 Tablet is also used to treat severe inflammatory diseases of the skin, Crohn's disease, ulcerative colitis, and some blood disorders.
- Azathioprine-50 Tablet contains 'Azathioprine', which is an immunosuppressant that works by reducing the function of the cells and causing inflammation in the joint tissues. It reduces pain and inflammation and slows joint damage and disease progression over time.
- Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azathioprine-50 Tablet helps stop your body from rejecting a new organ by suppressing your immune system.
How Azathioprine-50 Tablet Works
Azathioprine-50 Tablet contains 'Azathioprine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azathioprine-50 Tablet helps stop your body from rejecting a new organ by suppressing your immune system.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Azathioprine-50 Tablet
- Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
- Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
- Limit alcohol intake and abstain from smoking to promote general wellbeing.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
What if I have taken an overdose of Azathioprine-50 Tablet
Do not take more than the prescribed dose of Azathioprine-50 Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, nausea, vomiting, fever, sore throat, chills and other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Drug Warnings
- Do not take Azathioprine-50 Tablet if you are allergic to any immunosuppressant medicines or Azathioprine.
- Let your doctor know before using Azathioprine-50 Tablet if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, immunodeficiency syndrome, or if you have a condition where your body produces too little of a natural chemical called thiopurine methyltransferase (TPMT), or if you have received any vaccinations.
- Do not take Azathioprine-50 Tablet if you are pregnant or planning for pregnancy, as Azathioprine-50 Tablet is a Pregnancy category risk D medicine, which can cause serious congenital disabilities to the unborn baby.
- Azathioprine-50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk.
- While taking Azathioprine-50 Tablet , avoid contact with anyone who has had shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately, as it requires special treatment if you have not had these illnesses.
- Azathioprine-50 Tablet causes dizziness and drowsiness, so drive with caution.
- Azathioprine-50 Tablet should not be given to children as safety and efficacy have not been established.
- Avoid consuming alcohol along with Azathioprine-50 Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition.
- Using Azathioprine-50 Tablet for a long time can increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukaemia (blood cancer), and skin cancer.
- Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Azathioprine-50 Tablet .
Drug-Drug Interactions
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Taking Azathioprine-50 Tablet and Febuxostat together can increase the blood levels of Azathioprine-50 Tablet
How to manage the interaction:
Taking Azathioprine-50 Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Azathioprine-50 Tablet and Febuxostat together can increase the blood levels of Azathioprine-50 Tablet
How to manage the interaction:
Taking Azathioprine-50 Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
When Azathioprine-50 Tablet is taken with Teriflunomide, may raise the risk of side effects affecting bone marrow function, resulting in low levels of different types of blood cells. This can increase your chances of developing anemia, bleeding issues, or infections.
How to manage the interaction:
Taking Azathioprine-50 Tablet with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience paleness, exhaustion, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
When Azathioprine-50 Tablet is taken with Teriflunomide, may raise the risk of side effects affecting bone marrow function, resulting in low levels of different types of blood cells. This can increase your chances of developing anemia, bleeding issues, or infections.
How to manage the interaction:
Taking Azathioprine-50 Tablet with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience paleness, exhaustion, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Taking Azathioprine-50 Tablet with Leflunomide can increase the risk of side effects which may lead to anemia, bleeding problems, or infections.
How to manage the interaction:
Taking Leflunomide with Azathioprine-50 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Taking Azathioprine-50 Tablet with Leflunomide can increase the risk of side effects which may lead to anemia, bleeding problems, or infections.
How to manage the interaction:
Taking Leflunomide with Azathioprine-50 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AzathioprineVoclosporin
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Taking Azathioprine-50 Tablet with Voclosporin may lead to a higher chance of severe infections and certain cancers, such as skin cancer and lymph gland cancer (lymphoma).
How to manage the interaction:
Although taking Azathioprine-50 Tablet and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like fever, chills, sore throat, muscle aches, blood in coughing fluid, red or inflamed skin, or body sores it is recommended to contact a doctor right away. Other symptoms such as weight loss, pain during urination, or difficulty breathing should also be reported promptly. Do not discontinue any medications without consulting a doctor.
Taking Azathioprine-50 Tablet with Voclosporin may lead to a higher chance of severe infections and certain cancers, such as skin cancer and lymph gland cancer (lymphoma).
How to manage the interaction:
Although taking Azathioprine-50 Tablet and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like fever, chills, sore throat, muscle aches, blood in coughing fluid, red or inflamed skin, or body sores it is recommended to contact a doctor right away. Other symptoms such as weight loss, pain during urination, or difficulty breathing should also be reported promptly. Do not discontinue any medications without consulting a doctor.
AzathioprineCertolizumab
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
When Azathioprine-50 Tablet and Certolizumab are taken together, they may raise the risk of severe infections
How to manage the interaction:
Although there is a possible interaction between Azathioprine-50 Tablet and certolizumab, you can take these medicines together if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
When Azathioprine-50 Tablet and Certolizumab are taken together, they may raise the risk of severe infections
How to manage the interaction:
Although there is a possible interaction between Azathioprine-50 Tablet and certolizumab, you can take these medicines together if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Taking Azathioprine-50 Tablet with Deferiprone can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azathioprine-50 Tablet and Deferiprone, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Azathioprine-50 Tablet with Deferiprone can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azathioprine-50 Tablet and Deferiprone, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Taking Azathioprine-50 Tablet with Natalizumab can raise the risk of severe infections.
How to manage the interaction:
Although taking Azathioprine-50 Tablet and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Azathioprine-50 Tablet with Natalizumab can raise the risk of severe infections.
How to manage the interaction:
Although taking Azathioprine-50 Tablet and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Coadministration of baricitinib and Azathioprine-50 Tablet can raise the risk of developing harmful infections.
How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azathioprine-50 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Coadministration of baricitinib and Azathioprine-50 Tablet can raise the risk of developing harmful infections.
How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azathioprine-50 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
Co-administration of Allopurinol with Azathioprine-50 Tablet may increase the effects of Azathioprine-50 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Azathioprine-50 Tablet and allopurinol, but it can be taken if prescribed by a doctor. However, if you experience chills, fever, body pains, sore throat, weakness, muscle pain, mouth sores, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Allopurinol with Azathioprine-50 Tablet may increase the effects of Azathioprine-50 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Azathioprine-50 Tablet and allopurinol, but it can be taken if prescribed by a doctor. However, if you experience chills, fever, body pains, sore throat, weakness, muscle pain, mouth sores, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor's advice.
AzathioprineGolimumab
Severe
How does the drug interact with Azathioprine-50 Tablet-50 Tablet:
When Azathioprine-50 Tablet and Golimumab are taken together, they may raise the risk of severe infections
How to manage the interaction:
There may be a possibility of interaction between Azathioprine-50 Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
When Azathioprine-50 Tablet and Golimumab are taken together, they may raise the risk of severe infections
How to manage the interaction:
There may be a possibility of interaction between Azathioprine-50 Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Practising yoga may also help improve joint flexibility and manage pain.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
- De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
- Acupuncture, massage, and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
- Avoid smoking and alcohol consumption.
Habit Forming
No
Therapeutic Class
IMMUNOSUPPRESSANTS
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Alcohol
Caution
You are recommended to avoid alcohol consumption while taking Azathioprine-50 Tablet . It could lead to increased dizziness and drowsiness.
Pregnancy
Caution
Azathioprine-50 Tablet is a Category D pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.
Breast Feeding
Caution
It is not recommended to take Azathioprine-50 Tablet while you are breastfeeding. Azathioprine-50 Tablet passes into breast milk.
Driving
Caution
Azathioprine-50 Tablet may cause dizziness, drowsiness, and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
Take Azathioprine-50 Tablet only after the doctor's prescription, especially if you are dealing with Liver diseases/conditions as your doctor may adjust the dose as required.
Kidney
Consult your doctor
Please consult your doctor if you have kidney impairment before taking Azathioprine-50 Tablet .
Children
Unsafe
Azathioprine-50 Tablet should not be used by children below 18 years of age, as the efficacy and safety have not been established.
Heart
Consult your doctor
Please consult your physician if you have any heart-related problems before taking Azathioprine-50 Tablet .
Geriatrics
Caution
Exercise caution while giving Azathioprine-50 Tablet in geriatric patients. Close monitoring of the individual is required.
FAQs
Country of origin
India
Manufacturer/Marketer address
886 South Civil Line, Jat Colony, Muzaffarnagar. Up
Other Info - AZA0106
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