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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Azee 500 Injection 5 ml is an antibiotic used in treating bacterial infections . It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. Common side effects include pain, itching, swelling or redness at the injection site, diarrhoea, nausea, vomiting.

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Whats That

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Composition :

AZITHROMYCIN-500MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Azee 500 Injection 5 ml

Azee 500 Injection 5 ml is used to treat infections caused by bacteria, such as pneumonia (lung infection) and infections of the reproductive organs. It is prescribed for treating severe infections when oral therapy is ineffective. A bacterial infection is a condition in which bacteria grow in the body and cause an infection. 

Azee 500 Injection 5 ml contains azithromycin, which slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. Azee 500 Injection 5 ml does not treat a viral infection like the flu or a common cold.

Not everyone who receives Azee 500 Injection 5 ml will experience these side effects. You may experience pain, itching, swelling or redness at the site of injection, stomach cramps, nausea, diarrhoea, wind, dizziness, headache, and indigestion. Most of these side effects of Azee 500 Injection 5 ml do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Azee 500 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Do not stop receiving Azee 500 Injection 5 ml even if you feel better. It is advised to complete the treatment course for better results. 

Inform your physician if you are allergic to Azee 500 Injection 5 ml, or have any history of muscle problems, arrhythmia, or low potassium or magnesium levels. Let your doctor know if you have/had liver problems; your doctor may need to monitor your liver function. Let your doctor know if you are pregnant or breastfeeding before taking Azee 500 Injection 5 ml. 

Uses of Azee 500 Injection 5 ml

Azee 500 Injection 5 ml is used in the treatment of bacterial infections. The detailed uses of Azee 500 Injection 5 ml are as follows:<br/>

  • Treatment of Bacterial Infections: Azee 500 Injection 5 ml is commonly prescribed for managing bacterial infections, including respiratory tract infections such as pneumonia and bronchitis.<br/>
  • Skin and Soft Tissue Infections: Azee 500 Injection 5 ml effectively treats skin conditions like cellulitis and other soft tissue infections caused by bacteria that respond to this medication.<br/>
  • Sexually Transmitted Infections (STIs): Azee 500 Injection 5 ml is widely used in the treatment of STIs such as Chlamydia and gonorrhea, due to its efficacy against the bacteria responsible for these diseases.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use. • Azee 500 Injection 5 ml will be administered by the doctor or healthcare professional. • Do not self-administer.

Medicinal Benefits

  • Azee 500 Injection 5 ml slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.
  • It is better tolerated and has more effective tissue penetration than other similar antibiotics.
  • Doctors prescribe Azee 500 Injection 5 ml for people who are intolerant to penicillin antibiotics. 

How Azee 500 Injection 5 ml Works

Azee 500 Injection 5 ml contains 'Azithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Azee 500 Injection 5 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Azee 500 Injection 5 ml

Azee 500 Injection 5 ml is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. An overdose of Azee 500 Injection 5 ml may cause liver damage and irregular heart rhythm. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

  • Do not take Azee 500 Injection 5 ml if you are allergic or hypersensitive to azithromycin, any of its ingredients, any other macrolide antibiotic or ketolide (macrolide derivatives), or if you are taking ergotamine (used to treat migraine).
  • Consult your doctor if you are pregnant or breastfeeding before receiving Azee 500 Injection 5 ml.
  • Tell your doctor if you have any history of liver problems, jaundice, myasthenia gravis, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level).
  • In rare cases, the use of Azee 500 Injection 5 ml can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Azee 500 Injection 5 ml and call your doctor. However, do not take any anti-diarrheal medication until your doctor advises you to do so.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Azee 500 Injection 5 ml:
Co-administration of Azee 500 Injection 5 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Azee 500 Injection 5 ml but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azee 500 Injection 5 ml:
Taking Azee 500 Injection 5 ml with cabozantinb may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Azee 500 Injection 5 ml alongside cabozantinb can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
AzithromycinBedaquiline
Severe
How does the drug interact with Azee 500 Injection 5 ml:
Taking Azee 500 Injection 5 ml with bedaquiline may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Azee 500 Injection 5 ml alongside bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Azee 500 Injection 5 ml:
Teriflunomide can cause liver issues, and combining it with Azee 500 Injection 5 ml, can raise the risk.

How to manage the interaction:
Although administration of Azee 500 Injection 5 ml alongside teriflunomide can result in an interaction, it can be taken if a doctor has advised it. However, if you notice fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azee 500 Injection 5 ml:
Taking Azee 500 Injection 5 ml with ceritinib may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Azee 500 Injection 5 ml alongside ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AzithromycinAnagrelide
Severe
How does the drug interact with Azee 500 Injection 5 ml:
Taking Azee 500 Injection 5 ml with anagrelide may increase the risk of an abnormal heart rhythm. If you're dealing with other cardiac illnesses, electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
Although using Azee 500 Injection 5 ml and anagrelide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Azee 500 Injection 5 ml:
Coadministration of Azee 500 Injection 5 ml with nilotinib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although administration of Azee 500 Injection 5 ml alongside nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Azee 500 Injection 5 ml:
Taking amisulpride with Azee 500 Injection 5 ml increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Though using amisulpride and Azee 500 Injection 5 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, get medical treatment immediately. Do not discontinue any medications without consulting doctor.
How does the drug interact with Azee 500 Injection 5 ml:
Taking Azee 500 Injection 5 ml with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Though administration of Azee 500 Injection 5 ml alongside hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Azee 500 Injection 5 ml:
Taking Morphine with Azee 500 Injection 5 ml may raise blood levels and side effects of morphine.

How to manage the interaction:
Although administration of Azee 500 Injection 5 ml alongside morphine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Azee 500 Injection 5 ml to restore healthy bacteria in the intestine that may have been killed due to the use of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Azee 500 Injection 5 ml.
  • Avoid intake of alcoholic beverages with Azee 500 Injection 5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Azee 500 Injection 5 ml in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Caution

It is advisable not to take or limit alcohol as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

It is not known if Azee 500 Injection 5 ml passes into breastmilk. Please consult your doctor.

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Driving

Unsafe

Azee 500 Injection 5 ml may cause dizziness, tiredness, or weakness. So avoid driving or operating machinery if you experience any of these symptoms.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function or discontinue treatment.

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Kidney

Consult your doctor

Consult your doctor if you have kidney problems as your doctor may need to adjust the dose.

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Children

Unsafe

Azee 500 Injection 5 ml is not recommended for use in children as safety and effectiveness have not been established.

Have a query?

FAQs

Azee 500 Injection 5 ml belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria such as pneumonia (lung infection) and pelvic infections (infection of the reproductive organs). It is prescribed for treating severe infections or when oral therapy is ineffective.

Azee 500 Injection 5 ml kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.

Do not take antacids that contain aluminium or magnesium hydroxide within 2 hours of taking Azee 500 Injection 5 ml. Antacids can interact with Azee 500 Injection 5 ml and make it less effective when taken simultaneously.

Azee 500 Injection 5 ml can cause Clostridium difficile-associated diarrhoea (CDAD). If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should avoid taking Azee 500 Injection 5 ml if you have colitis (intestine inflammation), heart rhythm disorder, liver disease (like jaundice), and muscle problems (like myasthenia gravis). Contact your doctor if you have these conditions before taking Azee 500 Injection 5 ml.

Azee 500 Injection 5 ml should not be taken with any ergot derivates such as ergotamine used to treat migraine. Consult your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - AZE0003

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