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  3. Azithral 500 mg Injection 5 ml

Azithral 500 mg Injection 5 ml, Pack of 1 Injection
Azithral 500 mg Injection 5 ml, Pack of 1 Injection
Azithral 500 mg Injection 5 ml, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Azithral 500 mg Injection 5 ml is an antibiotic used in treating bacterial infections . It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. Common side effects include pain, itching, swelling or redness at the injection site, diarrhoea, nausea, vomiting.
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Composition :

AZITHROMYCIN-500MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Azithral 500 mg Injection 5 ml

Azithral 500 mg Injection 5 ml belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria. It is prescribed for treating severe infections or when oral therapy is ineffective. Azithral 500 mg Injection 5 ml is indicated in pneumonia (lung infection) and pelvic infections (infection of the reproductive organs). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiply very quickly.

Azithral 500 mg Injection 5 ml contains 'Azithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

Azithral 500 mg Injection 5 ml will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness at the site of injection, stomach cramps, nausea, diarrhoea, wind, dizziness, headache, and indigestion. Most of these side effects of Azithral 500 mg Injection 5 ml do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding; your doctor will prescribe Azithral 500 mg Injection 5 ml only if the benefits outweigh the risk. Let your doctor know if you have/had liver problems; your doctor may need to monitor your liver function. Let your doctor know about your medical condition and the medications you are taking to avoid any interactions. Azithral 500 mg Injection 5 ml may cause visual problems, do not drive or use machinery unless you are alert.

Uses of Azithral 500 mg Injection 5 ml

Treatment of Bacterial infections

Directions for Use

Azithral 500 mg Injection 5 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Azithral 500 mg Injection 5 ml belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria such as pneumonia (lung infection) and pelvic infections (infection of the reproductive organs). Azithral 500 mg Injection 5 ml works by preventing the production of proteins required by the bacteria for its survival. Thereby kills the bacteria and treats infections. Azithral 500 mg Injection 5 ml is prescribed for treating severe infections or when oral therapy is ineffective.

How Azithral 500 mg Injection 5 ml Works

Azithral 500 mg Injection 5 ml contains 'Azithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Azithral 500 mg Injection 5 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Azithral 500 mg Injection 5 ml

Azithral 500 mg Injection 5 ml is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. An overdose of Azithral 500 mg Injection 5 ml may cause liver damage and irregular heart rhythm. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Azithral 500 mg Injection 5 ml if you are allergic or hypersensitive to azithromycin, any of its ingredients, any other macrolide antibiotic or ketolide (macrolide derivatives), or if you are taking ergotamine (used to treat migraine). Consult your doctor if you are pregnant or breastfeeding. Inform your doctor if you have/had myasthenia gravis, psychiatric disorders, migraine, heart, kidney or liver problems.

Drug-Drug Interactions

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AzithromycinZiprasidone
Critical
AzithromycinLeflunomide
Severe

Drug-Drug Interactions

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AzithromycinZiprasidone
Critical
How does the drug interact with Azithral 500 mg Injection 5 ml:
Co-administration of Azithral 500 mg Injection 5 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Azithral 500 mg Injection 5 ml but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AzithromycinLeflunomide
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Azithral 500 mg Injection 5 ml with leflunomide can cause liver problems.

How to manage the interaction:
Although there is an interaction between Azithral 500 mg Injection 5 ml and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AzithromycinPanobinostat
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Azithral 500 mg Injection 5 ml with Panobinostat increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside Panobinostat can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
AzithromycinAmiodarone
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Coadministration of Azithral 500 mg Injection 5 ml with amiodarone may increase the risk of irregular heart rhythm and increases the blood levels of Amiodarone.

How to manage the interaction:
Although using Azithral 500 mg Injection 5 ml with amiodarone can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AzithromycinThioridazine
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Azithral 500 mg Injection 5 ml with thioridazine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside thioridazine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
AzithromycinMorphine
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Morphine with Azithral 500 mg Injection 5 ml may raise blood levels and side effects of morphine.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside morphine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination contact a doctor. Do not discontinue any medications without consulting a doctor.
AzithromycinMethadone
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Azithral 500 mg Injection 5 ml with methadone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical treatment immediately. Do not discontinue any medications without consulting a doctor.
AzithromycinTeriflunomide
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Teriflunomide can cause liver issues, and combining it with Azithral 500 mg Injection 5 ml, can raise the risk.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside teriflunomide can result in an interaction, it can be taken if a doctor has advised it. However, if you notice fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor. Do not stop using any medications without talking to a doctor.
AzithromycinNilotinib
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Coadministration of Azithral 500 mg Injection 5 ml with nilotinib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although administration of Azithral 500 mg Injection 5 ml alongside nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
AzithromycinPazopanib
Severe
How does the drug interact with Azithral 500 mg Injection 5 ml:
Taking Azithral 500 mg Injection 5 ml with pazopanib may increases the blood levels of pazopanib. This increases the risk of serious side effects.

How to manage the interaction:
Although there is an interaction between Azithral 500 mg Injection 5 ml and pazopanib, it can be taken if a doctor has advised it. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, lack of appetite, nausea, vomiting, dark urine, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Azithral 500 mg Injection 5 ml to restore healthy bacteria in the intestine that may have been killed due to the use of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Azithral 500 mg Injection 5 ml.
  • Avoid intake of alcoholic beverages with Azithral 500 mg Injection 5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Azithral 500 mg Injection 5 ml in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Azithral 500 mg Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advisable not to take or limit alcohol as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is not known if Azithral 500 mg Injection 5 ml passes into breastmilk. Please consult your doctor.

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Driving

Caution

Azithral 500 mg Injection 5 ml may cause dizziness, tiredness, or weakness. So avoid driving or operating machinery if you experience any of these symptoms.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function or discontinue treatment.

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Kidney

Caution

Consult your doctor if you have kidney problems as your doctor may need to adjust the dose.

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Children

Caution

Azithral 500 mg Injection 5 ml is not recommended for use in children as safety and effectiveness have not been established.

Have a query?

FAQs

Azithral 500 mg Injection 5 ml belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria such as pneumonia (lung infection) and pelvic infections (infection of the reproductive organs). It is prescribed for treating severe infections or when oral therapy is ineffective.

Azithral 500 mg Injection 5 ml kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.

Do not take antacids that contain aluminium or magnesium hydroxide within 2 hours of taking Azithral 500 mg Injection 5 ml. Antacids can interact with Azithral 500 mg Injection 5 ml and make it less effective when taken simultaneously.

Azithral 500 mg Injection 5 ml can cause Clostridium difficile-associated diarrhoea (CDAD). If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should avoid taking Azithral 500 mg Injection 5 ml if you have colitis (intestine inflammation), heart rhythm disorder, liver disease (like jaundice), and muscle problems (like myasthenia gravis). Contact your doctor if you have these conditions before taking Azithral 500 mg Injection 5 ml.

Azithral 500 mg Injection 5 ml should not be taken with any ergot derivates such as ergotamine used to treat migraine. Consult your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - AZI0017

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/1276/pil
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/50733s5lbl.pdf
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