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Bdfucil 100/224 Capsule 14's is an anti-cancer medicines indicated for first-line treatment of metastatic colorectal cancer. It contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer. In some cases, this medication may cause side effects such as diarrhoea, nausea, vomiting, and abdominal pain. This medicine is not recommended for children as safety and effectiveness have not been established.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Bdfucil 100/224 Capsule 14's

Bdfucil 100/224 Capsule 14's is an oral medication used to treat certain types of cancers, including cancers of the colon, rectum, stomach, and breast. It belongs to a group of medicines that work by interfering with the growth and spread of cancer cells in the body. By targeting these rapidly dividing cells, the medication helps control the progression of the disease.

To achieve the best results, you must take Bdfucil 100/224 Capsule 14's regularly and exactly as your doctor has prescribed. It is crucial to take this medication on an empty stomach, either one hour before or two hours after a meal, to ensure your body absorbs it correctly. Alongside your treatment, staying well-hydrated and eating a balanced, easy-to-digest diet can support your body through the recovery process.

While taking Bdfucil 100/224 Capsule 14's, you may experience some common side effects such as mild stomach upset, loss of appetite, or tiredness. However, you must contact your doctor immediately if you experience severe symptoms, such as persistent diarrhea, a high fever, unusual bleeding, or yellowish skin and eyes.

Do not take this if you have a known severe allergy to this medication, a severe genetic enzyme deficiency known as DPD deficiency, or severe liver damage. It is also important to tell your doctor before starting treatment if you have a history of kidney disease or bone marrow problems.

This medication can interact with other substances, including blood thinners, which may increase your risk of bleeding. You should avoid drinking alcohol during your treatment as it can increase stress on your liver. Always consult your doctor before using Bdfucil 100/224 Capsule 14's if you are pregnant, planning to become pregnant, breastfeeding, or if you are managing health conditions in an elderly patient.

Uses of Bdfucil 100/224 Capsule 14's

This medicine is used as an anticancer treatment to help slow the growth and spread of certain types of solid tumors. The detailed uses of this medicine are as follows:

  • Colorectal cancer: Bdfucil 100/224 Capsule 14's is used to treat cancers of the colon and rectum by slowing the growth of cancer cells. It may help shrink tumors or reduce the risk of cancer recurrence after surgery when prescribed as part of a treatment plan.
  • Gastric cancer: Bdfucil 100/224 Capsule 14's helps manage stomach cancer by interfering with the multiplication of abnormal cancer cells and slowing disease progression.
  • Breast cancer: In selected cases, Bdfucil 100/224 Capsule 14's may be prescribed to help control advanced or recurring breast cancer by reducing the growth and spread of cancer cells.

Key Benefits

Bdfucil 100/224 Capsule 14's provides an effective oral chemotherapy option that helps manage certain cancers while offering convenience and flexibility during treatment. Its benefits include:

  • Helps slow the growth and spread of cancer cells by targeting and destroying abnormal cells.
  • Provides the convenience of oral treatment, allowing patients to take therapy at home and reducing the need for frequent hospital visits for intravenous chemotherapy.
  • Helps eliminate microscopic cancer cells that may remain after surgery, supporting efforts to reduce the risk of cancer recurrence.
  • Offers a manageable treatment approach through scheduled oral cycles, helping patients maintain their daily routine and quality of life during therapy.
  • Supports long-term cancer management when used as part of a treatment plan prescribed by an oncologist.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication, to improve effectiveness.
  • Take the medicine an hour before or after food or as advised by the doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Bdfucil 100/224 Capsule 14's Works

Bdfucil 100/224 Capsule 14's contains Tegafur and Uracil. Tegafur: It is a prodrug (a medicine that becomes active only after your body processes it) that is converted inside the body into 5-fluorouracil (5-FU), an active anticancer medicine. Once converted, 5-FU mainly blocks the production of DNA by inhibiting an enzyme needed for cancer cell growth. It can also interfere with the instructions cancer cells use to grow and copy themselves, ultimately causing cancer cell death. Uracil: It slows the breakdown of the active ingredient by blocking the dihydropyrimidine dehydrogenase (DPD) enzyme, which normally breaks down 5-FU. This helps the active medicine remain effective for longer and work well even at lower doses. This is also why people with complete DPD deficiency should not take this medicine.
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Alcohol

Consult your doctor

It is not known if alcohol affects Bdfucil 100/224 Capsule 14's. Please consult your doctor.

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Pregnancy

Unsafe

Bdfucil 100/224 Capsule 14's is not recommended during pregnancy as it may cause foetal harm. Women with childbearing potential are advised to avoid becoming pregnant during treatment with Bdfucil 100/224 Capsule 14's.

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Breast Feeding

Unsafe

This medicine may pass into breast milk. Breastfeeding is not recommended during treatment with Bdfucil 100/224 Capsule 14's and for a few months afterwards.

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Driving

Caution

Bdfucil 100/224 Capsule 14's may cause tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Caution

When Bdfucil 100/224 Capsule 14's is used, patients with mild to moderate hepatic dysfunction should be closely monitored by liver function tests.

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Kidney

Consult your doctor

In patients with renal impairment, Bdfucil 100/224 Capsule 14's has not been used extensively. When using this medicine in such patients, physicians ought to proceed with caution.

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Children

Unsafe

Bdfucil 100/224 Capsule 14's is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Bdfucil 100/224 Capsule 14's should be used with caution in patients with heart problems and only under close medical supervision. Rare but serious side effects like arrhythmia, angina, or myocardial infarction have been reported, so regular cardiac monitoring is essential during treatment.

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Geriatrics

Caution

Bdfucil 100/224 Capsule 14's can be used in geriatric patients, but only under close medical supervision. Studies suggest it’s generally well tolerated in older adults, though side effects like gastrointestinal discomfort or fatigue may occur. Regular monitoring is important to manage dosage and watch for bone marrow suppression or liver strain.

What if I have taken an overdose of Bdfucil 100/224 Capsule 14's

If you suspect an overdose, seek immediate emergency medical attention or contact a poison control center right away. Symptoms of an overdose may include severe nausea, vomiting, or severe diarrhea.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Aim to drink at least two to three liters of water daily to keep your kidneys functioning well and prevent dehydration from potential diarrhea.
  • Eat small, frequent meals: If you experience a loss of appetite or mild nausea, eating five or six small, nutritious meals throughout the day is often easier to tolerate than three large ones.
  • Maintain gentle mouth care: Use a soft-bristled toothbrush and rinse your mouth with a mild saltwater solution after meals to help prevent painful mouth sores.
  • Protect your skin from the sun: This medication can make your skin more sensitive to sunburn. Wear protective clothing, a wide-brimmed hat, and apply a broad-spectrum sunscreen when outdoors.
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How Soon It Starts Working

The time required for Bdfucil 100/224 Capsule 14's to start to work: The time required for Bdfucil 100/224 Capsule 14's to show its action is unknown. The time for which the effects of Bdfucil 100/224 Capsule 14's last: The duration of action for Bdfucil 100/224 Capsule 14's is unknown.

What if you forget to take Bdfucil 100/224 Capsule 14's

If you miss a dose, skip the missed dose entirely and take your next dose at its regularly scheduled time. Do not take a double dose to make up for a missed one. Contact your doctor or pharmacist if you miss multiple doses.

Storage

• Store Bdfucil 100/224 Capsule 14's at room temperature, specifically below 30°C (86°F), in a dry place away from direct heat, moisture, and light.

Drug Warnings

  • Inspect capsules before use: Check the blister packaging before each dose. Do not take capsules that are cracked, broken, damaged, or damp.
  • Maintain proper hygiene: Wash your hands thoroughly with soap and water immediately after handling the capsules to avoid accidental exposure.
  • Monitor for fever and infection: Check your body temperature regularly and seek medical attention if you develop a fever, as oral chemotherapy may temporarily reduce white blood cell counts and increase infection risk.
  • Avoid live vaccines: Do not receive live vaccines while taking this medicine unless your doctor has confirmed that it is safe to do so.
  • Use effective contraception: Use highly effective birth control during treatment and for the duration recommended by your doctor, as this medicine may harm an unborn baby.
  • Discuss fertility before treatment: If you plan to have children in the future, speak with your oncologist before starting chemotherapy. Depending on your situation, options such as sperm banking or egg/embryo preservation may be considered before treatment begins.

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  • Blood thinners (like warfarin): Combining these can significantly increase your risk of bleeding. Your doctor may need to monitor your blood clotting times more frequently.
  • Certain antiviral medicines: Some antiviral medicines can greatly increase the amount of chemotherapy medicine in your body, leading to serious side effects. Tell your doctor or pharmacist about all medicines you take so they can check whether any antiviral medicines should be avoided.
  • Phenytoin: Bdfucil 100/224 Capsule 14's may increase the levels of this seizure medication in your body, which requires careful monitoring by your doctor.

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verifiedApollotooltip

No clinically significant food interactions are known with Bdfucil 100/224 Capsule 14's when used as directed.

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Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Bdfucil 100/224 Capsule 14's is used to treat Colorectal cancer.
Bdfucil 100/224 Capsule 14's works by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.
Bdfucil 100/224 Capsule 14's may cause diarrhoea in some cases. Drink plenty of fluids if you have diarrhoea. Consult the doctor if you experience severe diarrhoea; your doctor may initiate supportive care or interrupt medication based on your condition. In patients with severe diarrhoea, careful monitoring and fluid and electrolyte replacement are recommended to prevent dehydration.
Bdfucil 100/224 Capsule 14's may reduce the number of white blood cells, which help fight infections. This might increase the risk of infections. Consult the doctor if you experience symptoms of infection, such as a fever, or if you suddenly feel unwell.
Bdfucil 100/224 Capsule 14's may affect your ability to become pregnant or father a child. Prior to the start of the treatment, discuss with your doctor if you have any concerns about fertility.
No, you must take Bdfucil 100/224 Capsule 14's on an empty stomach, either one hour before or two hours after a meal. Food interferes with how well your body absorbs this medication. Talk to your doctor if you struggle with this schedule.
If you vomit after taking your dose, do not take an additional capsule to replace it. Wait until your next scheduled dose time and take your regular dose, then notify your doctor or pharmacist of the event.
Yes, Bdfucil 100/224 Capsule 14's is an oral chemotherapy medication. It is designed to target, slow down, and destroy rapidly dividing cancer cells. Talk to your doctor to understand how this fits into your overall treatment plan.
Your treatment duration depends on your specific type of cancer, how your tumor responds, and how well your body tolerates the therapy. Your doctor will outline your exact schedule and cycle lengths.
It is highly recommended to avoid alcohol during your treatment, as alcohol can place additional stress on your liver and worsen side effects like nausea and dehydration. Talk to your doctor for personalized advice.
Some patients experience mild hair thinning while taking Bdfucil 100/224 Capsule 14's, but complete hair loss is less common than with traditional intravenous chemotherapy. Talk to your doctor if you have concerns about hair thinning.
Most patients can drive while taking Bdfucil 100/224 Capsule 14's, but you should see how the medication affects you first, as it can cause fatigue or dizziness. If you feel tired or unwell, avoid driving and talk to your doctor.
If you develop mouth sores, practice gentle mouth hygiene by rinsing with warm saltwater and using a very soft toothbrush. Avoid spicy, acidic, or extremely hot foods, and talk to your doctor for treatment recommendations.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - BDF0002
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