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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bemdiff 180 mg Tablet is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bemdiff 180 mg Tablet

Bemdiff 180 mg Tablet is used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Bemdiff 180 mg Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

In some cases, Bemdiff 180 mg Tablet may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Bemdiff 180 mg Tablet if you are pregnant or breastfeeding. Bemdiff 180 mg Tablet is not recommended for children below 18 years, as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Uses of Bemdiff 180 mg Tablet

Bemdiff 180 mg Tablet is used in the treatment of high cholesterol. The detailed uses of Bemdiff 180 mg Tablet are as follows:

  • Lowering LDL cholesterol: Bemdiff 180 mg Tablet is prescribed to reduce low-density lipoprotein cholesterol (LDL-C), commonly known as bad cholesterol. It works by inhibiting the enzyme ATP citrate lyase, which plays a key role in cholesterol production in the liver.
  • Treatment of primary hyperlipidemia: Bemdiff 180 mg Tablet is used in adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia, a genetic condition that causes very high cholesterol levels.
  • Cardiovascular risk reduction: In patients with established heart disease or those at high risk, Bemdiff 180 mg Tablet may be used alongside statins or as an alternative when statins are not tolerated, to help reduce the risk of heart attack, stroke, or coronary procedures.

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Directions for Use

  • Bemdiff 180 mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication for effective results.
  • Swallow Bemdiff 180 mg Tablet as a whole with water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Bemdiff 180 mg Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids).
  • Bemdiff 180 mg Tablet contains bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol.
  • This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol.
  • It helps decrease bad cholesterol in the body.

How Bemdiff 180 mg Tablet Works

Bemdiff 180 mg Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

Storage

• Store in a cool and dry place away from sunlight.• Keep Bemdiff 180 mg Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Bemdiff 180 mg Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.

What if I have taken an overdose of Bemdiff 180 mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Bemdiff 180 mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

  • Do not take Bemdiff 180 mg Tablet if you are allergic to any of its components or if you are pregnant or breastfeeding.
  • Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems.
  • Consult the doctor immediately if you become pregnant during treatment with Bemdiff 180 mg Tablet .
  • Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Bemdiff 180 mg Tablet with Hydrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Hydrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Levofloxacin and Bemdiff 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Levofloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Using Simvastatin together with Bemdiff 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Co-administration of Simvastatin and Bemdiff 180 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any muscle pain, weakness, fever, dark urine, joint pain or swelling, vomiting, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Bemdiff 180 mg Tablet and Gemifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Gemifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Cinoxacin with Bemdiff 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Bemdiff 180 mg Tablet with Cinoxacin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you feel pain or swelling in joints, consult your doctor immediately. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Taking Bemdiff 180 mg Tablet with Ciprofloxacin may can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints, consult a doctor immediately. Exercise and using the affected area should be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Betamethasone with Bemdiff 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Betamethasone with Bemdiff 180 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience pain, swelling, or inflammation in joints consult a doctor immediately. Exercising or using the injured area should also be avoided. Do not discontinue the medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Budesonide with Bemdiff 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Budesonide with Bemdiff 180 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience pain, swelling, or inflammation in joints consult a doctor immediately. Exercising or using the injured area should also be avoided. Do not discontinue the medications without a doctor's advice.
How does the drug interact with Bemdiff 180 mg Tablet:
Co-administration of Bemdiff 180 mg Tablet with Dexamethasone can result in tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Dexamethasone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking Bemdiff 180 mg Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Bemdiff 180 mg Tablet:
Taking Bemdiff 180 mg Tablet with Fludrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdiff 180 mg Tablet can be taken with Fludrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation in joints, consult a doctor. Exercising or using the injured area should also be avoided Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by engaging in any physical activity, such as swimming, brisk walking, or jogging. Take stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Bemdiff 180 mg Tablet . Please consult a doctor.

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Pregnancy

Unsafe

Bemdiff 180 mg Tablet may harm the unborn baby. Do not take Bemdiff 180 mg Tablet if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Bemdiff 180 mg Tablet .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Bemdiff 180 mg Tablet if you are breastfeeding.

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Driving

Safe if prescribed

Bemdiff 180 mg Tablet has little or no influence on your ability to drive.

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Liver

Consult your doctor

It is not known if Bemdiff 180 mg Tablet is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

It is not known if Bemdiff 180 mg Tablet is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Bemdiff 180 mg Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Take Bemdiff 180 mg Tablet with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Bemdiff 180 mg Tablet if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Bemdiff 180 mg Tablet can be used in the elderly when prescribed by a doctor. If you have any concerns about using Bemdiff 180 mg Tablet , please consult a doctor.

FAQs

Country of origin

India

Manufacturer/Marketer address

142 Ab, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - BEM0032

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