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  3. Bendastes 100 mg Injection 4 ml

Bendastes 100 mg Injection 4 ml, Pack of 1
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bendastes 100 mg Injection 4 ml is used to treat Non-Hodgkin's disease and Chronic Lymphocytic Leukaemia. Bendastes 100 mg Injection 4 ml contains Bendamustine; it works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. This medication is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Synonym :

BENDAMUSTINE HYDROCHLORIDE

Composition :

BENDAMUSTINE-25Mg

Manufacturer/Marketer :

Halsted Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Bendastes 100 mg Injection 4 ml

Bendastes 100 mg Injection 4 ml belongs to a class of anti-cancer medicines used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. This medicine is used in the treatment of Chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin’s leukemia (NHL) that has progressed during six months of treatment with rituximab or rituximab-containing treatment.

Bendastes 100 mg Injection 4 ml contains Bendamustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

Bendastes 100 mg Injection 4 ml may cause certain side effects, such as nausea, vomiting, diarrhea, stomach pain, anorexia, decreased weight, constipation, fever, decreased platelet count, fatigue, cough, headache, rash, injection site reactions and pain at the site of injection. If the side effects bother you, inform your doctor. A trained healthcare professional will administer Bendastes 100 mg Injection 4 ml. Hence, do not self-administer.

Bendastes 100 mg Injection 4 ml should be avoided if you are allergic to it or any other components present in it. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Bendastes 100 mg Injection 4 ml is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Bendastes 100 mg Injection 4 ml

Bendastes 100 mg Injection 4 ml is used in the treatment of Non-Hodgkin&#039;s disease and Chronic Lymphocytic Leukaemia. The detailed uses of Bendastes 100 mg Injection 4 ml are as follows:<br/>• Chronic Lymphocytic Leukemia (CLL): Bendastes 100 mg Injection 4 ml is used as a first-line treatment or in relapsed cases to slow disease progression.<br/>• Indolent B-cell Non-Hodgkin Lymphoma (NHL): Bendastes 100 mg Injection 4 ml is used to treat Indolent B-cell Non-Hodgkin Lymphoma (NHL) especially in patients who have not responded to other therapies.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Bendastes 100 mg Injection 4 ml will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Bendastes 100 mg Injection 4 ml contains Bendamustine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. This medicine is used in the treatment of chronic lymphocytic leukemia and non-Hodgkin’s leukemia.

How Bendastes 100 mg Injection 4 ml Works

Bendastes 100 mg Injection 4 ml contains Bendamustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Bendastes 100 mg Injection 4 ml out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Bendastes 100 mg Injection 4 ml

As Bendastes 100 mg Injection 4 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Bendastes 100 mg Injection 4 ml may cause rapid, irregular, or pounding heartbeat.

Drug Warnings

Bendastes 100 mg Injection 4 ml should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before receiving this injection, inform your doctor if you have any history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Bendastes 100 mg Injection 4 ml may cause myelosuppression, active infections, severe skin reactions, tumor lysis syndrome (tumor cells release their contents into the bloodstream), other malignancies, and hypersensitivity reactions in some patients. Hence, careful monitoring should be done during the entire treatment. Bendastes 100 mg Injection 4 ml may cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Before nursing, a breastfeeding mother should ask her oncologist whether this medicine is safe for use or not. Bendastes 100 mg Injection 4 ml is not recommended for use in children as the safety and efficacy are not established.

Diet & Lifestyle Advise

  • After your treatment begins, dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Caution

Limit or avoid consumption of alcohol as it may worsen your condition.

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Pregnancy

Unsafe

Bendastes 100 mg Injection 4 ml is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Bendastes 100 mg Injection 4 ml. Use reliable methods of birth control while on treatment with Bendastes 100 mg Injection 4 ml.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before receiving Bendastes 100 mg Injection 4 ml. You should not breastfeed while on treatment with Bendastes 100 mg Injection 4 ml.

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Driving

Not applicable

-

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Bendastes 100 mg Injection 4 ml. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. Bendastes 100 mg Injection 4 ml is not recommended for use in patients with severe liver disease.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Bendastes 100 mg Injection 4 ml. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. This medicine should be avoided for patients with CrCl &lt;40 ml/min.

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Children

Unsafe

Bendastes 100 mg Injection 4 ml is not recommended for use in children as the safety and efficacy is not established.

Have a query?

FAQs

Bendastes 100 mg Injection 4 ml is used to treat Non-Hodgkin’s disease and Chronic Lymphocytic Leukaemia.

Bendastes 100 mg Injection 4 ml contains Bendamustine, which inhibits the DNA and RNA transcription essential for cancer cell growth.

Bendastes 100 mg Injection 4 ml may cause reactivation of serious infections, myelosuppression, tumour lysis syndrome, and anaphylactic reactions in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Bendastes 100 mg Injection 4 ml is safe when used as per the dose and duration advised by a doctor.

Bendastes 100 mg Injection 4 ml has the vesicant (irritant) properties.

Yes, the use of Bendastes 100 mg Injection 4 ml can cause hair loss and constipation as a side effect. This will gradually reduce over time and does not require any medical attention. However, please contact a doctor if this condition persists for longer or worsens.

Bendastes 100 mg Injection 4 ml can cross the blood-brain barrier and can be utilized for treating cancers that have spread to the brain.

Bendastes 100 mg Injection 4 ml may cause side effects such as diarrhoea, back pain, vomiting, stomach pain, cough, pain at the site of injection, fever, constipation, decreased blood pressure, rashes, and decreased weight. Please, contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

SCF NO 265, SECOND FLOOR MOTOR MARKET MANIMAJRA Chandigarh, Chandigarh, 160101 India
Other Info - BEN0896

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022303lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a608034.html#
  3. https://reference.medscape.com/drug/bendeka-belrapzo-bendamustine-342133
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/bendamustine
  5. https://www.bendeka.com/

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