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Biomenden 12.5 mg Injection 20 ml belongs to the group of medications called 'calcium sensitizer' primarily used to treat hospitalized patients with acute heart failure. Heart failure can occur when your heart cannot pump blood sufficiently required to the remainder of the body. A heart attack is the blockage of blood flow to the heart muscle. The blockage is most often a build-up of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Heart attack and brain stroke can occur simultaneously as the brain's stroke blood supply gets interrupted, causing a part of the brain to die.
Biomenden 12.5 mg Injection 20 ml contains 'levosimendan', which works by increasing the heart's sensitivity to calcium ion (Ca) without increasing the amount of calcium present in the heart's muscles cells. Biomenden 12.5 mg Injection 20 ml widens up the heart's blood vessels (coronary artery) and, in turn, relaxes the smooth muscles of the heart so that blood and oxygen can flow easily to the whole body.
The most common side effects of Biomenden 12.5 mg Injection 20 ml are headache, low blood pressure, and nausea (stomach discomfort). Most of these side effects of Biomenden 12.5 mg Injection 20 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Biomenden 12.5 mg Injection 20 ml should not be given to the patients with low blood pressure (hypotension), dehydration, low blood count, chest pain (angina), or have abnormal heart rhythm. Pregnant or lactating women should consult a doctor before administration of Biomenden 12.5 mg Injection 20 ml. This medicine should not be given to children and adolescents under 18 years of age.
Biomenden 12.5 mg Injection 20 ml is used to manage acute heart failure in adults. The detailed uses of Biomenden 12.5 mg Injection 20 ml include:
Biomenden 12.5 mg Injection 20 ml is a calcium sensitizer that enhances the heart's pumping forces and allows blood vessels to relax. Improvement of the cardiac function by Biomenden 12.5 mg Injection 20 ml helps reduce the congestion in your lungs and enhances blood and oxygen delivery to the organs. Thus, treatment with Biomenden 12.5 mg Injection 20 ml relieves the shortness of breath from severe heart failure.
Unsafe
Avoid consumption of alcohol while taking Biomenden 12.5 mg Injection 20 ml as it may cause increased dizziness.
Unsafe
Do not take Biomenden 12.5 mg Injection 20 ml if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Consult a doctor immediately if you become pregnant while taking Biomenden 12.5 mg Injection 20 ml.
Caution
It is not recommended to take Biomenden 12.5 mg Injection 20 ml if you are breastfeeding. Consult your doctor before taking Biomenden 12.5 mg Injection 20 ml; your doctor will decide whether Biomenden 12.5 mg Injection 20 ml can be taken by breastfeeding mothers or not.
Caution
Biomenden 12.5 mg Injection 20 ml may cause dizziness. Do not drive or operate machinery unless you are alert.
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Caution
Biomenden 12.5 mg Injection 20 ml is not recommended for children as the safety and effectiveness have not been established.
Caution
Biomenden 12.5 mg Injection 20 ml should be administered with caution, especially if you have a history of heart problems. Please inform your doctor about any existing heart problems before receiving Biomenden 12.5 mg Injection 20 ml.
Caution
Biomenden 12.5 mg Injection 20 ml should be administered with caution in elderly patients due to an increased risk of side effects. If you have any concerns, please consult your doctor.
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Do not use Biomenden 12.5 mg Injection 20 ml if you are allergic to any of its contents. Do not take Biomenden 12.5 mg Injection 20 ml if you are pregnant, think you may be pregnant, or trying for pregnancy. Consult your doctor before taking Biomenden 12.5 mg Injection 20 ml if you are breastfeeding. Try not to stop taking this medicine of your own as stopping Biomenden 12.5 mg Injection 20 ml abruptly may worsen your condition and increase your risk of a future heart attack. Biomenden 12.5 mg Injection 20 ml should not be given to the patients with low blood pressure (hypotension), dehydration, low blood count, chest pain (angina), or have abnormal heart rhythm. This medicine should not be given to children and adolescents under 18 years of age. Biomenden 12.5 mg Injection 20 ml should not be given into the same vein as other medicines except for heart-related medicines like frusemide, digoxin or glyceryl trinitrate. This is because if you have been given other heart-related medicines through your veins, your blood pressure might drop if you are given Biomenden 12.5 mg Injection 20 ml.
Drug-Drug Interactions: Biomenden 12.5 mg Injection 20 ml may have interaction with medications used to treat high blood pressure like Atenolol, drugs used to treat attention deficit hyperactivity disorder like Atomoxetine. This is not a complete list of all the possible drug interactions.
Drug-Food Interactions: Avoid consuming grapefruit and grapefruit juice with Biomenden 12.5 mg Injection 20 ml. Do not take St. John’s wort (herbal supplement to treat depression) with Biomenden 12.5 mg Injection 20 ml.
Drug-Disease Interaction: Biomenden 12.5 mg Injection 20 ml may have interactions with disease conditions such as rhabdomyolysis (muscle breakdown), Reye’s syndrome, asthma, gout, glaucoma, liver disease, diabetes, and cognitive impairment.
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