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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Biophenicol Succinate Injection 1gm is used to treat bacterial infections. It contains Chloramphenicol, which works by preventing the synthesis of essential proteins necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating infection. Common side effects of Biophenicol Succinate Injection 1gm are nausea, vomiting, diarrhoea, dry mouth, and headache.
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Whats That

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Composition :

CHLORAMPHENICOL-1GM

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Biophenicol Succinate Injection 1gm

Biophenicol Succinate Injection 1gm belongs to the group of medicines called antibiotics used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Biophenicol Succinate Injection 1gm does not work against infections caused by viruses, including colds and flu.
 
Biophenicol Succinate Injection 1gm contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, kills the bacteria and helps in treating infection. Biophenicol Succinate Injection 1gm is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.
 
In some cases, you may experience common side effects such as nausea, vomiting, diarrhoea, dry mouth and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Do not use Biophenicol Succinate Injection 1gm if you are pregnant or breastfeeding. Biophenicol Succinate Injection 1gm is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interaction

Uses of Biophenicol Succinate Injection 1gm

Treatment of Bacterial infections

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Biophenicol Succinate Injection 1gm will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Biophenicol Succinate Injection 1gm belongs to the group of antibiotic medicines used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Biophenicol Succinate Injection 1gm contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating infection. Biophenicol Succinate Injection 1gm is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

How Biophenicol Succinate Injection 1gm Works

Biophenicol Succinate Injection 1gm contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, kills the bacteria and helps in treating infection. Biophenicol Succinate Injection 1gm is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

Storage

• Store in a cool and dry place away from sunlight.• Keep Biophenicol Succinate Injection 1gm out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Biophenicol Succinate Injection 1gm
  • Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
  • Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
  • Limit alcohol intake and abstain from smoking to promote general wellbeing.
  • Treatments include blood transfusions, immunosuppressive therapy and bone marrow transplants.
  • Get adequate sleep and rest.
  • Avoid high-contact sports and activities.
  • If you experience significant anemia symptoms like weakness, fatigue (overtiredness), or shortness of breath, consult your doctor to determine the medication causing it. Your doctor may advise you to discontinue that medicine immediately and recommend supportive care.
  • In certain cases, blood transfusions, immunosuppressive therapy or bone marrow transplants may be required to stabilize the patient based on the severity and underlying cause of anemia.
  • Take iron supplements if advised by your doctor.
  • Include foods rich in iron like dark leafy greens, legumes, red meat, fish, poultry and fortified cereals in your diet.
  • In some cases, vitamin B 12 supplements may be advised if vitamin B12 deficiency is a contributing factor.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Biophenicol Succinate Injection 1gm

As Biophenicol Succinate Injection 1gm is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Biophenicol Succinate Injection 1gm may cause nausea and vomiting, abdominal distension, metabolic acidosis, hypotension, hypothermia, cardiovascular collapse, and coma.

Drug Warnings

Do not take Biophenicol Succinate Injection 1gm if you are allergic to any of its components; or if you are pregnant or breastfeeding. Inform your doctor if you are taking any medicines which may cause bone marrow depression if you have a cold, throat infection, viral influenza, kidney or liver problems, or if you are about to be or have recently been vaccinated. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal/vitamin supplements.

Drug-Drug Interactions

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ChloramphenicolLomitapide
Critical
Critical

Drug-Drug Interactions

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ChloramphenicolLomitapide
Critical
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking lomitapide with Biophenicol Succinate Injection 1gm can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Biophenicol Succinate Injection 1gm with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm with triazolam can increased the effects of Biophenicol Succinate Injection 1gm.

How to manage the interaction:
Taking Triazolam with Biophenicol Succinate Injection 1gm is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolFlibanserin
Critical
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Flibanserin with Biophenicol Succinate Injection 1gm may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Biophenicol Succinate Injection 1gm with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Naloxegol and Biophenicol Succinate Injection 1gm can significantly increase the blood levels of naloxegol that may increase the risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sweating, runny nose, or abdominal pain contact your doctor know right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biophenicol Succinate Injection 1gm:
Co-administration of acalabrutinib with Biophenicol Succinate Injection 1gm can significantly increases the blood levels of acalabrutinib.

How to manage the interaction:
Although there is a interaction between Biophenicol Succinate Injection 1gm and Acalabrutinib, but it can be taken together if prescribed by your doctor. However, if you experience symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination, call your doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Biophenicol Succinate Injection 1gm:
When Everolimus is taken with Biophenicol Succinate Injection 1gm that may increase the risk of side effects.

How to manage the interaction:
Co-administration of Biophenicol Succinate Injection 1gm with Everolimus can result in an interaction, but it can be taken if a doctor has advised it. If you experience any unusual symptoms like persistent cough, fever, chills, mouth ulcers, paleness, unusual bruising, bleeding or blood in stools or urine, it's important to contact a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm and Ivacaftor may increase the blood levels of ivacaftor that increases risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Ivacaftor together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact a doctor. Do not stop using any medications without a doctor's advice.
ChloramphenicolHydrocodone
Severe
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm and Hydrocodone can significantly increase the blood levels of cariprazine.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm with Hydrocodone can possibly result in an interaction, it can be taken if your doctor has advised it. If you're having any of these symptoms like dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures, it's important to let your doctor know. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Clozapine with Biophenicol Succinate Injection 1gm may increase the risk of infections.

How to manage the interaction:
Although there is a interaction between Clozapine and Biophenicol Succinate Injection 1gm, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm and Butorphanol can significantly increase the blood levels of Butorphanol that may increase the risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm with Butorphanol can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures contact your doctor know. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Biophenicol Succinate Injection 1gm. Please consult a doctor.

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Pregnancy

Unsafe

Biophenicol Succinate Injection 1gm is not recommended for use during pregnancy.

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Breast Feeding

Unsafe

Biophenicol Succinate Injection 1gm is not recommended for use during breastfeeding.

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Driving

Safe if prescribed

Biophenicol Succinate Injection 1gm is unlikely to affect your ability to drive.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

Biophenicol Succinate Injection 1gm is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight.

Have a query?

FAQs

Biophenicol Succinate Injection 1gm is used to treat Bacterial infections.

Biophenicol Succinate Injection 1gm works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills bacteria and helps treat infections.

Diarrhoea might be a side-effect of Biophenicol Succinate Injection 1gm. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Biophenicol Succinate Injection 1gm is associated with various forms of anaemia (decreased white, red blood cells and platelets). This may lead to loss of immunity and the development of leukaemia in a few people. Consult a doctor if you have any concerns.

Biophenicol Succinate Injection 1gm should be used with great care in newborn babies to avoid grey syndrome, a condition occurring due to excessive toxic chloramphenicol metabolites. Treatment should be stopped immediately if the symptoms are identified.

Headache could be a side effect of Biophenicol Succinate Injection 1gm. It is not necessary for everyone to experience this side effect. However, if the condition persists or worsens, consult a doctor.

Biophenicol Succinate Injection 1gm mostly works shortly after administration, but to eliminate all the harmful bacteria, it may take a few days. Completing the full course of treatment is important for the Biophenicol Succinate Injection 1gm effectiveness. If your condition doesn’t improve or worsens, consult your doctor.

Inform your doctor if you don’t get better after completing the full course of Biophenicol Succinate Injection 1gm. Also, inform about the unwanted effects and the symptoms that worsen while using Biophenicol Succinate Injection 1gm.

You are recommended not to stop taking Biophenicol Succinate Injection 1gm without consulting your doctor as stopping it suddenly can cause withdrawal symptoms. Therefore, continue taking Biophenicol Succinate Injection 1gm for the duration prescribed and if you experience any difficulty while taking Biophenicol Succinate Injection 1gm, consult your doctor so that the dose may be reduced gradually.

The side effects of Biophenicol Succinate Injection 1gm include nausea, vomiting, diarrhoea, headache, and dry mouth. These do not require any medical treatments as they gradually reduce over time. Please, consult the doctor if these side effects persist longer.

Country of origin

INDIA

Manufacturer/Marketer address

BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.
Other Info - BIO0033

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