Does Cphenicol Injection cause diarrhoea?

Diarrhoea might be a side-effect of Cphenicol Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Does Cphenicol Injection cause blood problems?

Cphenicol Injection is associated with various forms of anaemia (decreased white, red blood cells and platelets). This may lead to loss of immunity and the development of leukaemia in a few people. Consult a doctor if you have any concerns.

Does Cphenicol Injection cause grey syndrome?

Cphenicol Injection should be used with great care in newborn babies to avoid grey syndrome, a condition occurring due to excessive toxic chloramphenicol metabolites. Treatment should be stopped immediately if the symptoms are identified.

Does Cphenicol Injection cause headache?

Headache could be a side effect of Cphenicol Injection. It is not necessary for everyone to experience this side effect. However, if the condition persists or worsens, consult a doctor.

How long does Cphenicol Injection takes to work?

Cphenicol Injection mostly works shortly after administration, but to eliminate all the harmful bacteria, it may take a few days. Completing the full course of treatment is important for the Cphenicol Injection effectiveness. If your condition doesn’t improve or worsens, consult your doctor.

What if I don't get better after using Cphenicol Injection?

Inform your doctor if you don’t get better after completing the full course of Cphenicol Injection. Also, inform about the unwanted effects and the symptoms that worsen while using Cphenicol Injection.

Can I stop taking Cphenicol Injection when my symptoms are relieved?

You are recommended not to stop taking Cphenicol Injection without consulting your doctor as stopping it suddenly can cause withdrawal symptoms. Therefore, continue taking Cphenicol Injection for the duration prescribed and if you experience any difficulty while taking Cphenicol Injection, consult your doctor so that the dose may be reduced gradually.

What are the side effects of Cphenicol Injection?

The side effects of Cphenicol Injection include nausea, vomiting, diarrhoea, headache, and dry mouth. These do not require any medical treatments as they gradually reduce over time. Please, consult the doctor if these side effects persist longer.

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cphenicol Injection is used to treat bacterial infections. It contains Chloramphenicol, which works by preventing the synthesis of essential proteins necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating infection. Common side effects of Cphenicol Injection are nausea, vomiting, diarrhoea, dry mouth, and headache.

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About Cphenicol Injection

Cphenicol Injection belongs to the group of medicines called antibiotics used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Cphenicol Injection does not work against infections caused by viruses, including colds and flu.

Cphenicol Injection contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, kills the bacteria and helps in treating infection. Cphenicol Injection is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

In some cases, you may experience common side effects such as nausea, vomiting, diarrhoea, dry mouth and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not use Cphenicol Injection if you are pregnant or breastfeeding. Cphenicol Injection is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interaction

Uses of Cphenicol Injection

Treatment of Bacterial infections

Directions for Use

Cphenicol Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Cphenicol Injection belongs to the group of antibiotic medicines used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Cphenicol Injection contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating infection. Cphenicol Injection is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

How Cphenicol Injection Works

Cphenicol Injection contains â€˜Chloramphenicolâ€™ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, kills the bacteria and helps in treating infection. Cphenicol Injection is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

Storage

Store in a cool and dry place away from sunlight

Side effects of Cphenicol Injection

Bone Marrow Suppression

Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
Limit alcohol intake and abstain from smoking to promote general wellbeing.

Aplastic Anemia

Treatments include blood transfusions, immunosuppressive therapy and bone marrow transplants.
Get adequate sleep and rest.
Avoid high-contact sports and activities.

Anemia Due To Damage To Stem Cells

If you experience significant anemia symptoms like weakness, fatigue (overtiredness), or shortness of breath, consult your doctor to determine the medication causing it. Your doctor may advise you to discontinue that medicine immediately and recommend supportive care.
In certain cases, blood transfusions, immunosuppressive therapy or bone marrow transplants may be required to stabilize the patient based on the severity and underlying cause of anemia.
Take iron supplements if advised by your doctor.
Include foods rich in iron like dark leafy greens, legumes, red meat, fish, poultry and fortified cereals in your diet.
In some cases, vitamin B 12 supplements may be advised if vitamin B12 deficiency is a contributing factor.

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Low Level Of Granulocytes (A Type Of White Blood Cells)

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Cphenicol Injection

As Cphenicol Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Cphenicol Injection may cause nausea and vomiting, abdominal distension, metabolic acidosis, hypotension, hypothermia, cardiovascular collapse, and coma.

Drug Warnings

Do not take Cphenicol Injection if you are allergic to any of its components; or if you are pregnant or breastfeeding. Inform your doctor if you are taking any medicines which may cause bone marrow depression if you have a cold, throat infection, viral influenza, kidney or liver problems, or if you are about to be or have recently been vaccinated. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal/vitamin supplements.

Drug-Drug Interactions

ChloramphenicolFlibanserin

Critical

ChloramphenicolTriazolam

Critical

Drug-Drug Interactions

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ChloramphenicolFlibanserin

Critical

How does the drug interact with Cphenicol Injection:
Taking Flibanserin with Cphenicol Injection may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Cphenicol Injection with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.

ChloramphenicolTriazolam

Critical

How does the drug interact with Cphenicol Injection:
Taking Cphenicol Injection with triazolam can increased the effects of Cphenicol Injection.

How to manage the interaction:
Taking Triazolam with Cphenicol Injection is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.

ChloramphenicolLomitapide

Critical

How does the drug interact with Cphenicol Injection:
Taking lomitapide with Cphenicol Injection can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Cphenicol Injection with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

ChloramphenicolOxycodone

Severe

How does the drug interact with Cphenicol Injection:
Taking oxycodone with Cphenicol Injection, it may increase the blood levels of oxycodone that may increase the risk of side effects.

How to manage the interaction:
Although taking Cphenicol Injection and Oxycodone together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment contact a doctor. Do not stop using any medications without talking to a doctor.

ChloramphenicolBrigatinib

Severe

How does the drug interact with Cphenicol Injection:
Taking brigatinib with Cphenicol Injection may increase the blood levels of brigatinib that may increase risk of side effects.

How to manage the interaction:
Co-administration of Cphenicol Injection with Brigatinib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, or pain and burning during urination. Do not discontinue any medications without first consulting your doctor.

ChloramphenicolClozapine

Severe

How does the drug interact with Cphenicol Injection:
Taking Clozapine with Cphenicol Injection may increase the risk of infections.

How to manage the interaction:
Although there is a interaction between Clozapine and Cphenicol Injection, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination contact your doctor right away. Do not stop using any medications without a doctor's advice.

ChloramphenicolNaloxegol

Severe

How does the drug interact with Cphenicol Injection:
Taking Naloxegol and Cphenicol Injection can significantly increase the blood levels of naloxegol that may increase the risk of side effects.

How to manage the interaction:
Although taking Cphenicol Injection and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sweating, runny nose, or abdominal pain contact your doctor know right away. Do not stop using any medications without a doctor's advice.

ChloramphenicolCisapride

Severe

How does the drug interact with Cphenicol Injection:
Taking cisapride together with Cphenicol Injection may significantly increase the blood levels of cisapride that may increase risk of side effects.

How to manage the interaction:
Co-administration of Cphenicol Injection with Cisapride can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately If you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

ChloramphenicolLemborexant

Severe

How does the drug interact with Cphenicol Injection:
When Lemborexant is taken with Cphenicol Injection, may increase the blood levels of Lemborexant.

How to manage the interaction:
Although taking Cphenicol Injection and Lemborexant together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like feeling down, having thoughts of hurting yourself, or having a headache, it's important to reach out to your doctor. Do not stop using any medications without talking to a doctor.

ChloramphenicolAcalabrutinib

Severe

How does the drug interact with Cphenicol Injection:
Co-administration of acalabrutinib with Cphenicol Injection can significantly increases the blood levels of acalabrutinib.

How to manage the interaction:
Although there is a interaction between Cphenicol Injection and Acalabrutinib, but it can be taken together if prescribed by your doctor. However, if you experience symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination, call your doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS