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BIOPIPER TZ INJECTION 4.5GM

Manufacturer

Biocon Ltd

Pack Of

1 INJECTION

In Stock

Prescription Required
Product Details

About BIOPIPER TZ INJECTION 4.5GM

BIOPIPER TZ INJECTION 4.5GM belongs to the 'Antibiotics' class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.

BIOPIPER TZ INJECTION 4.5GM contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of 'Penicillin antibiotics.' It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. In BIOPIPER TZ INJECTION 4.5GM, Tazobactam works by preventing bacteria from destroying Piperacillin.

BIOPIPER TZ INJECTION 4.5GM is available in the form of intravenous injection. Like all medicines, BIOPIPER TZ INJECTION 4.5GM also causes side effects, although not everybody gets them. Common side effects of BIOPIPER TZ INJECTION 4.5GM include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly. 

Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits. Do not use BIOPIPER TZ INJECTION 4.5GM while having vaccinations with live bacterial vaccines (typhoid vaccine) since BIOPIPER TZ INJECTION 4.5GM may affect vaccines' activity. BIOPIPER TZ INJECTION 4.5GM should be used during pregnancy only if the doctor advised you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking BIOPIPER TZ INJECTION 4.5GM. 

Uses of BIOPIPER TZ INJECTION 4.5GM

Bacterial infections, hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and uterine infections.

Medicinal Benefits

BIOPIPER TZ INJECTION 4.5GM contains two medicines, namely: Piperacillin and Tazobactam. Piperacillin is a Penicillin antibiotic. It acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. In BIOPIPER TZ INJECTION 4.5GM, Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, BIOPIPER TZ INJECTION 4.5GM helps treat various bacterial infections of the stomach, lungs, skin and uterus.

Directions for Use

BIOPIPER TZ INJECTION 4.5GM is available in the form of intravenous injection. Your doctor will advise the dose and duration based on the severity of your infection.Injection: BIOPIPER TZ INJECTION 4.5GM is given as an intravenous (into a vein) injection by a doctor or nurse.

Storage

Store in a cool and dry place away from sunlight

Side Effects of BIOPIPER TZ INJECTION 4.5GM

  • Nausea
  • Constipation
  • Diarrhoea
  • Headache
  • Trouble sleeping 

In-Depth Precautions and Warning

Drug Warnings

If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases, please inform your doctor before starting BIOPIPER TZ INJECTION 4.5GM. Please tell your doctor if you are undergoing dialysis treatment since Penicillin antibiotics like Piperacillin are removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Clostridium difficile associated diarrhoea (CDAD) is reported during usage of antibiotics like BIOPIPER TZ INJECTION 4.5GM. Therefore, please undergo an examination to rule out the chances of CDAD if you experience diarrhoea following BIOPIPER TZ INJECTION 4.5GM therapy. 

Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since BIOPIPER TZ INJECTION 4.5GM may affect vaccines' activity. BIOPIPER TZ INJECTION 4.5GM should be used with caution during pregnancy since it crosses the placenta in humans. BIOPIPER TZ INJECTION 4.5GM is also excreted into breast milk. Please seek medical advice if you are pregnant or breastfeeding before taking BIOPIPER TZ INJECTION 4.5GM. Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Sometimes, antibiotic medications can cause antibiotic resistance. In such cases, your doctor may prescribe other antibiotics, you are not resistant. 

Safety Advice

  • Safety Warning

    Alcohol

    Avoid alcohol consumption while taking BIOPIPER TZ INJECTION 4.5GM to prevent unpleasant side-effects, such as nausea and vomiting.

  • Safety Warning

    Pregnancy

    BIOPIPER TZ INJECTION 4.5GM should be used with caution during pregnancy since it crosses the placenta in humans. Please consult your doctor before taking BIOPIPER TZ INJECTION 4.5GM if you are pregnant or planning to conceive.

  • Safety Warning

    Breast Feeding

    There is limited data on how BIOPIPER TZ INJECTION 4.5GM affects breastfed infants. BIOPIPER TZ INJECTION 4.5GM is excreted into breast milk. Please consult your doctor before taking BIOPIPER TZ INJECTION 4.5GM if you are breastfeeding.

  • Safety Warning

    Driving

    It is unknown whether BIOPIPER TZ INJECTION 4.5GM affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking BIOPIPER TZ INJECTION 4.5GM, do not drive or operate any machinery.

  • Safety Warning

    Liver

    Let your doctor know if you have any history of liver diseases before taking BIOPIPER TZ INJECTION 4.5GM. Your doctor will prescribe BIOPIPER TZ INJECTION 4.5GM only if the benefits outweigh the risk.

  • Safety Warning

    Kidney

    Penicillin antibiotics are easily removed by dialysis. Beta-lactam antibiotics like Tazobactam should be cautiously administered in patients with renal impairment. Prolonged use of BIOPIPER TZ INJECTION 4.5GM may cause nephrotoxicity and alterations in renal function, hence please let your doctor know if you have any history of kidney diseases before taking BIOPIPER TZ INJECTION 4.5GM. Your doctor will prescribe BIOPIPER TZ INJECTION 4.5GM only if the benefits outweigh the risk.

Habit Forming

No

Diet & Lifestyle Advise

  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing BIOPIPER TZ INJECTION 4.5GM properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid intake of alcoholic beverages with BIOPIPER TZ INJECTION 4.5GM as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the BIOPIPER TZ INJECTION 4.5GM in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections. 

Special Advise

  • Renal, hepatic, and blood function tests are advised during prolonged therapy to rule out any toxicity caused due to overdose of BIOPIPER TZ INJECTION 4.5GM. 
  • Clostridium difficile associated diarrhoea (CDAD) is reported during usage of antibiotics like BIOPIPER TZ INJECTION 4.5GM. Please see your doctor if you experience prolonged diarrhoea.
  • Penicillin antibiotics are easily removed during dialysis, hence let your doctor know if you are undergoing dialysis treatment so that the dose can be scheduled after the dialysis.
  • BIOPIPER TZ INJECTION 4.5GM may also affect urine glucose tests, hence inform your doctor beforehand if you are using BIOPIPER TZ INJECTION 4.5GM.

Other Information (BIO0617)

This item is Not Returnable.

Expires on or after - Mar-22

Patients Concern

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever and tiredness. 

Hospital-acquired pneumonia/ nosocomial pneumonia: It is a lower respiratory infection of the lungs that occurs during a hospital stay.

Ventilator-associated pneumonia: A lung infection occurs in people who are on mechanical ventilation breathing machines in hospitals.

FAQs

BIOPIPER TZ INJECTION 4.5GM contains Piperacillin and Tazobactam. Piperacillin inhibits bacterial cell wall synthesis, and Tazobactam prevents the bacteria from gaining resistance against Piperacillin. Thus BIOPIPER TZ INJECTION 4.5GM helps in treating various bacterial infections.

BIOPIPER TZ INJECTION 4.5GM should be used with proper caution and doctor consultation if you have any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases and undergoing dialysis.

BIOPIPER TZ INJECTION 4.5GM can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start BIOPIPER TZ INJECTION 4.5GM if you are undergoing any vaccinations.

It is recommended to complete the course of BIOPIPER TZ INJECTION 4.5GM even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking BIOPIPER TZ INJECTION 4.5GM for as long as your doctor has prescribed to treat your condition effectually.

PRODUCT SUBSTITUTES

BIOPIPER TZ INJECTION 4.5GM

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100

BIOPIPER TZ INJECTION 4.5GM

BIOPIPER TZ INJECTION 4.5GM

MRP: 490.50

Vial
1

4.5 gm Injection in 1 Vial