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compositionComposition:BLEOMYCIN-15IU
prescription
Prescription Medicine
info
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Bleosol 15U Injection is used to treat cancers in the head and neck, cervix and external genitalia, lymph node cancer, testicular cancer, and fluid accumulation in the lungs (as a result of cancer). It contains Bleomycin which works by preventing the cancer cells from multiplying and eventually kills them. In some cases, this medicine may cause side effects such as nausea, vomiting, weight loss, loss of appetite, nausea, vomiting, and hair loss. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BLEOMYCIN-15IU

Manufacturer/Marketer :

Vhb Life Sciences Inc

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bleosol 15U Injection

Bleosol 15U Injection is a specialised medication prescribed to treat various types of cancer, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, and testicular cancer. It is also used to treat squamous cell cancers affecting the head, neck, cervix, vulva, or penis, as well as to prevent fluid buildup around the lungs caused by tumors. This medicine works by targeting and stopping the growth of rapidly dividing cancer cells in the body.

Because this medication is given as an injection, your healthcare team will schedule and give your doses at specific intervals to ensure it works effectively. Since it is injected, you do not need to worry about taking it with or without food, but maintaining a consistent treatment schedule is vital. Making supportive lifestyle adjustments, such as drinking plenty of fluids and eating smaller, nutrient-rich meals, can help your body cope better during your treatment cycle.

While receiving this medicine, you may experience common side effects such as skin darkening, mild hair thinning, and temporary fever or chills shortly after your session. However, it is critical to contact your doctor immediately if you experience serious symptoms like a dry cough, shortness of breath, or chest pain, as these can point to serious lung issues. Regular monitoring by your medical team is essential to catch and manage these side effects early.

Before starting your treatment, tell your doctor if you have a history of kidney disease, lung conditions, or if you have ever had an allergic reaction to similar treatments. You should not receive this medicine if you have severe, pre-existing lung damage or a known allergy to any of its components. Your doctor will carefully review your medical history to ensure this treatment is safe for you.

This medicine can interact with other prescription drugs, alcohol, and lifestyle factors like smoking, which can significantly increase your risk of lung damage. It is also important to tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as these groups require special precautions and modified monitoring. Always discuss your complete medication list and lifestyle habits with your healthcare team before your first session.

Uses of Bleosol 15U Injection

Here are the common uses of Bleosol 15U Injection in the treatment and management of certain cancers and cancer-related conditions:

  • Testicular cancer: Used as part of a combination treatment plan to target, shrink, and destroy cancer cells in the testicles.
  • Hodgkin's and Non-Hodgkin's Lymphoma: Helps control and treat cancers that affect the lymphatic system, stopping the spread of abnormal white blood cells.
  • Squamous cell cancers: Used to treat outer-layer cell cancers of the head, neck, cervix, vulva, and penis when other treatments may not be sufficient.
  • Pleural effusion: Injected directly into the chest cavity to prevent the painful and dangerous buildup of fluid around the lungs caused by advanced cancers.

Key Benefits

Here are the key benefits of Bleosol 15U Injection when used as part of cancer treatment:

  • Slows cancer growth: Works by damaging the DNA of cancer cells, preventing them from growing and multiplying.
  • Helps shrink tumours: Reduces tumour size, making cancer easier to manage and improving the effectiveness of combination treatment regimens.
  • Supports cancer control: Helps limit the spread of cancer cells and increases the likelihood of achieving disease remission when used alongside other anticancer medicines.
  • Relieves symptoms of pleural effusion: Helps seal the space between the lung and chest wall (pleurodesis), preventing fluid from reaccumulating, reducing chest discomfort, and improving breathing.
Side effects of Bleosol 15U Injection
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Inflammation in the lungs needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Intake of cod liver oil can smoothen the functioning of the body process.
  • Rest and refrain from physical activity, and restart after a few days.
  • Avoid smoking as it can worsen the swelling.
  • Practice meditation and yoga to enhance lung efficiency gradually after consulting with your doctor.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.
  • If you experience abnormal breath sounds as a side effect of a medicine, consult your doctor.
  • Use a humidifier to add moisture in the air and relieve cough.
  • Drink hot tea with lemon, honey and a dash of cinnamon to help relieve cough and fight infection.
  • Take steam to help loosen phlegm.
  • Eat a healthy diet to boost immune system.
  • If you work in a toxic environment, cover your nose and mouth with a mask.
  • If you are breathing rapidly for a while, try to calm your mind and body.
  • For a while, try to breathe through your nose and breathe out through your mouth to control rapid breathing.
  • Take deep breaths and let them flow deep down; don't force yourself; let it out gently by counting from 1-5.
  • Sit in a place that is well-ventilated and has fresh air.
  • Take enough rest and stay pleasant to control rapid breathing.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Bleosol 15U Injection will be administered by a nurse or doctor.
  • Do not self-administer.

How Bleosol 15U Injection Works

Bleosol 15U Injection contains bleomycin, an anticancer medicine that belongs to a group of medicines known as antitumour antibiotics. It works by binding directly to the DNA inside cancer cells and causing breaks in the DNA strands through the formation of reactive oxygen molecules. This damage prevents cancer cells from repairing themselves, growing, and dividing. Cancer cells multiply much faster than normal cells, making them more susceptible to this DNA damage. By stopping their growth and triggering cell death, Bleosol 15U Injection helps shrink tumours, slow the spread of cancer, and improve the effectiveness of cancer treatment. It is commonly used as part of combination chemotherapy regimens for several types of cancer and may also be used to manage cancer-related pleural effusion by preventing fluid from reaccumulating around the lungs.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Bleosol 15U Injection. It could lead to avoiding unpleasant side-effects.

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Pregnancy

Unsafe

Bleosol 15U Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Bleosol 15U Injection and at least six months afterwards. Please discuss with your doctor any concerns regarding this.

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Breast Feeding

Unsafe

Bleosol 15U Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Bleosol 15U Injection may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Bleosol 15U Injection may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Bleosol 15U Injection. Your doctor will weigh the benefits and potential risks before prescribing them.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Bleosol 15U Injection. Your doctor will weigh the benefits and potential risks before prescribing them.

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Children

Unsafe

Bleosol 15U Injection should not be used by children, as the efficacy and safety have not been established.

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Heart

Caution

Limited data is available regarding the use of Bleosol 15U Injection in patients with heart problems. Please consult your doctor if you have any concerns regarding this.

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Geriatrics

Caution

Bleosol 15U Injection should be administered with caution in elderly patients due to an increased risk of side effects. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Bleosol 15U Injection

Because this medicine is given by healthcare professionals in a controlled clinical environment, an overdose is highly unlikely. However, if you suspect an error or experience severe breathing difficulties shortly after a session, notify your medical team immediately or seek emergency medical attention.

Diet & Lifestyle Advise

  • Prioritise lung health: Avoid smoking, vaping, and exposure to secondhand smoke or harsh chemical fumes, as your lungs are highly sensitive during this treatment.
  • Protect your skin: Wear protective clothing, hats, and high-SPF sunscreen when outdoors, as this medicine makes your skin highly sensitive to sunlight and prone to hyperpigmentation.
  • Stay hydrated: Drink plenty of water and clear fluids throughout the day to help your kidneys process and clear the medication from your body.
  • Eat gentle, nutritious meals: If you experience nausea or loss of appetite, eat small, frequent meals consisting of bland foods like crackers, toast, or rice to maintain your strength.
health query

Have a query?

How Soon It Starts Working

The time required for Bleosol 15U Injection to start to work: Bleosol 15U Injection ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Bleosol 15U Injection last: The duration of action for Bleosol 15U Injection is clinically unknown.

What if you forget to take Bleosol 15U Injection

If you miss an appointment for your injection, contact your clinic or doctor immediately to reschedule. It is very important to keep your treatment sessions as close to the planned schedule as possible. Do not try to double your dose or receive injections closer together than prescribed.

Storage

• Unopened vials of this medicine must be stored in a refrigerator between 2°C and 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Undergo regular lung tests: Ensure you complete all scheduled lung function tests (such as chest X-rays or breathing tests) before and during your treatment to monitor your lung health.
  • Inform other doctors: Always tell any doctor, dentist, or emergency medical professional that you are receiving this treatment, especially if you require surgery or oxygen therapy.
  • Monitor the injection site: Pay close attention to the area where the needle was placed; tell your nurse immediately if you feel burning, stinging, or see swelling during or after the injection.
  • Avoid live vaccines: Do not receive any live vaccines (such as the shingles or yellow fever vaccine) during your treatment without discussing it with your oncologist first.
  • Use reliable birth control: Both men and women must use effective birth control during and for several months after treatment to prevent pregnancy, as this medicine can cause severe harm to an unborn baby.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines and treatments may interact with Bleosol 15U Injection. Inform your doctor about all the medicines, supplements, and vaccines you are receiving before starting treatment.

  • Other chemotherapy drugs (like cisplatin): May reduce the kidney's ability to clear this medicine, increasing the risk of serious side effects, including lung toxicity.
  • Oxygen therapy: Receiving high concentrations of oxygen (such as during general anesthesia) can trigger or worsen lung damage caused by this medicine.
  • Live vaccines: Using live vaccines during chemotherapy can increase the risk of developing a severe infection from the vaccine itself.
BleomycinCladribine
Severe
BleomycinBaricitinib
Severe

Drug-Drug Interactions

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BleomycinCladribine
Severe
How does the drug interact with Bleosol 15U Injection:
The combined use of Bleosol 15U Injection and cladribine can increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Bleosol 15U Injection and Cladribine, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - make sure to contact your doctor right away. Do not stop using any medications without talking to your doctor.
BleomycinBaricitinib
Severe
How does the drug interact with Bleosol 15U Injection:
Combining Bleosol 15U Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Baricitinib and Bleosol 15U Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
BleomycinFilgrastim
Severe
How does the drug interact with Bleosol 15U Injection:
Combining Filgrastim with Bleosol 15U Injection can increase the risk of developing lung disorders.

How to manage the interaction:
There may be a possibility of interaction between Filgrastim and Bleosol 15U Injection, it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
BleomycinLeflunomide
Severe
How does the drug interact with Bleosol 15U Injection:
The use of leflunomide together with Bleosol 15U Injection may raise the risk of severe infections.

How to manage the interaction:
Although there is a possible interaction between Bleosol 15U Injection and Leflunomide, you can take these medicines together if prescribed by your doctor. If you notice any signs of infection like fever, chills, or a sore throat, or if you experience symptoms like diarrhea, muscle aches, or difficulty breathing, contact your doctor immediately. Additionally, if you notice any weight loss or pain or burning while urinating, let your doctor know." Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Bleosol 15U Injection when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Bleosol 15U Injection is used to treat cancer of the head and neck, cervix and external genitalia, lymph node cancer, testicular cancer, and fluid accumulation in the lungs (as a result of cancer).
Bleosol 15U Injection contains 'Bleomycin' is an anti-cancer medication that interferes with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Yes, the Bleosol 15U Injection commonly affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Bleosol 15U Injection. These effects are not long-lasting and may return after some time. If it matters to you, then inform your doctor for further advice.
Your doctor will decide the number of treatment cycles and the frequency of Bleosol 15U Injection to be taken, depending on the type and stage of cancer treated.
Bleosol 15U Injection should not be taken during pregnancy or if you are trying to become pregnant as Bleosol 15U Injection can cause birth defects, miscarriages, or harm unborn babies. Avoid becoming pregnant for at least six months after stopping the treatment with Bleosol 15U Injection.
Bleosol 15U Injection should be used with caution if you have a medical history of liver or kidney diseases, lung diseases (pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders, gastrointestinal diseases (peptic ulcer, ulcerative colitis), and active infections (including chickenpox).
Yes, Bleosol 15U Injection may cause pulmonary fibrosis, nausea or hair loss as side effects. However, consult your doctor if you notice these side effects.
Bleosol 15U Injection can cause pulmonary fibrosis due to its effect on lung tissue. The exact mechanism involves the lack of an enzyme in the lungs that metabolizes bleomycin, leading to the accumulation of the drug in lung tissue. This accumulation can cause oxidative damage and inflammation, resulting in scarring (fibrosis) of the lung tissue.
The common side effects of Bleosol 15U Injection are nausea, vomiting, weight loss, loss of appetite, nausea, vomiting, itching, tenderness, hair loss, and swelling of the fingertips. If any of these side effects persist or worsen, please consult your doctor.
It is given as an injection or infusion by a trained healthcare professional in a clinic or hospital. It can be injected into a vein, a muscle, under the skin, or directly into the chest cavity.
This medicine can sometimes affect the lungs, causing inflammation or scarring. Regular lung tests help your doctor monitor how well your lungs are working and ensure it is safe to continue treatment. Talk to your doctor if you have concerns.
You should consult your doctor before drinking alcohol. Alcohol can worsen side effects like nausea, fatigue, and dehydration, which are important to avoid during chemotherapy.
Contact your doctor or care team immediately if you develop a dry cough, shortness of breath, or fever, as these can be early signs of lung inflammation that require prompt medical attention.
This medicine can cause temporary skin changes, including hyperpigmentation (darkening) or red streaks, especially on areas exposed to friction or sunlight. These changes usually fade after treatment ends, but you should protect your skin from the sun.
Older adults, especially those over 70, may be more sensitive to the side effects of this medicine, particularly in the lungs and kidneys. Doctors carefully adjust doses and monitor elderly patients closely. Talk to your doctor about your specific health risks.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

50-Ab, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India
Other Info - BLE0038
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