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compositionComposition:BOSENTAN-62.5MG
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Prescription Medicine
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Bosentale-62.5 Tablet 10's is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It can even increase our exercise ability, delay disease progression, and improve quality of life. It contains Bosentan, which narrows the blood vessels and increases pressure in the lungs. It helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs. In some cases, you may experience swelling of legs and ankles, headaches, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

BOSENTAN-62.5MG

Manufacturer/Marketer :

Chemo Biological Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Bosentale-62.5 Tablet 10's

Bosentale-62.5 Tablet 10's is an oral prescription medicine used to treat pulmonary arterial hypertension, which is high blood pressure in the blood vessels that supply the lungs. It works by targeting specific proteins that cause these blood vessels to narrow, thereby improving blood flow and reducing the workload on your heart. This medicine is prescribed to help improve your physical exercise capacity and slow down the clinical worsening of your symptoms.

To get the most benefit, you must take Bosentale-62.5 Tablet 10's consistently every day, exactly as prescribed by your doctor. Taking this medicine at the same times each day helps maintain a steady level of the treatment in your bloodstream. You can take this tablet with or without food, making it easy to incorporate into your daily routine. Making sensible adjustments, such as adopting a low-sodium diet and engaging in gentle, doctor-approved physical activity, can significantly support your treatment results.

While taking Bosentale-62.5 Tablet 10's, some patients may experience mild, common side effects such as headaches, joint pain, or cold-like symptoms. However, because this medication can cause serious liver damage, it is critical to consult your doctor immediately if you develop symptoms such as dark urine, yellowing of your skin or eyes, or severe nausea. Regular blood monitoring is required to ensure this medicine remains safe for you to use.

Bosentale-62.5 Tablet 10's is not suitable for everyone. Do not take this if you are pregnant, planning to become pregnant, or have moderate-to-severe liver damage. Before starting, you must tell your doctor if you have a history of anemia, fluid retention, or pre-existing liver issues, so they can evaluate whether this medication is safe for your specific condition.

This medicine can interact with several substances; for example, it may reduce the effectiveness of hormonal birth control, and combining it with alcohol can increase the risk of low blood pressure and liver strain. Special patient groups, including those who are breastfeeding, planning a pregnancy, or elderly, must consult their doctor to carefully weigh the risks and benefits before using this medication.

Uses of Bosentale-62.5 Tablet 10's

Bosentale-62.5 Tablet 10's is used in the treatment of high blood pressure in the lungs and related conditions. The detailed uses of Bosentale-62.5 Tablet 10's are as follows:

  • Pulmonary Arterial Hypertension (PAH): Bosentale-62.5 Tablet 10's helps by widening the blood vessels in your lungs, which lowers the high blood pressure in these arteries and makes it easier for your heart to pump blood.
  • Systemic Sclerosis with Digital Ulcers: In certain clinical situations, this medicine helps reduce the development of new, painful finger ulcers by improving localized blood flow in patients with systemic sclerosis.

Key Benefits

Bosentale-62.5 Tablet 10's provides meaningful physical relief by managing the underlying constriction of your pulmonary blood vessels. By keeping these blood vessels open, the medication helps reduce the daily physical limitations caused by pulmonary arterial hypertension.

  • Improved Daily Stamina: Patients frequently notice they can walk longer distances and perform routine daily activities with much less shortness of breath and fatigue.
  • Delayed Disease Progression: Regular use of this medication helps slow down the worsening of your condition, helping to reduce the likelihood of hospital visits related to your blood pressure.
  • Prevention of Painful Ulcers: For those managing systemic sclerosis, this treatment helps limit the formation of new, painful open sores on the fingers, preserving hand movement and comfort.

Directions for Use

  • Always take Bosentale-62.5 Tablet 10's exactly as your doctor has instructed. Do not change your dose or stop the medication on your own.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the tablet.
  • You may take this medication with or without food. Try to take your doses at the same times every day to maintain a consistent amount of medicine in your body.
  • Because of severe safety risks to unborn babies, female patients of childbearing potential must strictly follow all required safety and monthly pregnancy testing protocols before and during treatment.

How Bosentale-62.5 Tablet 10's Works

Bosentale-62.5 Tablet 10's works by blocking the action of a natural substance in your body called endothelin-1. Endothelin-1 is a powerful chemical that causes the blood vessels in your lungs to tighten, narrow, and become thick. In individuals with pulmonary arterial hypertension, the body produces too much of this chemical, which restricts blood flow and forces the heart to work much harder to pump blood through the lungs. By binding to specific receptors, Bosentale-62.5 Tablet 10's prevents endothelin-1 from tightening the vessels. This allows the blood vessels to relax and widen. As a result, blood pressure in the lungs decreases, oxygen-rich blood flows more easily, and the strain on your heart is significantly reduced.
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Alcohol

Unsafe

Bosentale-62.5 Tablet 10's should not be taken along with alcohol to avoid unpleasant side effects.

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Pregnancy

Unsafe

Bosentale-62.5 Tablet 10's is a category X pregnancy drug, and it can cause harm to the baby, so it should not be taken if you are pregnant or planning to get pregnant.

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Breast Feeding

Unsafe

Bosentale-62.5 Tablet 10's is known to pass through breast milk and may cause harm to the baby, so it should not be taken if you are breastfeeding.

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Driving

Caution

Bosentale-62.5 Tablet 10's may cause hypotension (low blood pressure), which may make you feel dizzy. If you feel dizzy, please do not drive a car.

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Liver

Caution

Bosentale-62.5 Tablet 10's to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Bosentale-62.5 Tablet 10's to be taken with caution, especially if you have or have had a kidney disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Bosentale-62.5 Tablet 10's is not recommended for use in children.

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Heart

Safe if prescribed

Bosentale-62.5 Tablet 10's is generally safe for use in cardiac patients for the treatment of pulmonary arterial hypotension, if prescribed by the doctor.

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Geriatrics

Caution

Bosentale-62.5 Tablet 10's should be given with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Bosentale-62.5 Tablet 10's

If you suspect an overdose or have taken too much Bosentale-62.5 Tablet 10's, you may experience a sharp drop in blood pressure, resulting in severe dizziness, rapid heart rate, or fainting. Seek immediate emergency medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Limit Sodium Consumption: Reduce your daily salt intake to help manage fluid retention and keep your blood pressure stable. Avoid heavily processed foods and do not add extra table salt to your meals.
  • Track Your Weight Daily: Weigh yourself every morning at the same time. Report any sudden weight gain of 2 to 3 pounds in a single day or 5 pounds in a week to your doctor, as this can be an early sign of fluid retention.
  • Stay Safe with Mild Exercise: Engage in gentle, doctor-approved physical activities, such as light walking. Avoid strenuous exercises, heavy lifting, or activities that require you to strain or hold your breath.
  • Use Reliable Double Contraception: If you are a female who can become pregnant, you must use two reliable methods of non-hormonal birth control simultaneously. Hormonal methods (like birth control pills) are not completely reliable on their own while taking this medicine.
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How Soon It Starts Working

  • The time required for Bosentale-62.5 Tablet 10's to start to work: The time required for Bosentale-62.5 Tablet 10's to show its action is not clinically established.
  • The time for which the effects of Bosentale-62.5 Tablet 10's last: The duration of action for Bosentale-62.5 Tablet 10's is not clinically established.

What if you forget to take Bosentale-62.5 Tablet 10's

If you miss a dose of Bosentale-62.5 Tablet 10's, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you struggle to remember your doses.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Complete Your Monthly Liver Tests: You must complete a liver function blood test every single month during your treatment, as Bosentale-62.5 Tablet 10's can cause severe liver damage.
  • Get Monthly Pregnancy Tests: Female patients of childbearing potential must have a negative pregnancy test before starting, every month during treatment, and for one month after stopping the medication.
  • Monitor Your Legs for Swelling: Inspect your feet and ankles daily for new or worsening fluid retention, and report any changes to your healthcare provider immediately.
  • Check Your Red Blood Cells: Ensure you complete your scheduled blood count tests, as your doctor will need to monitor your blood for signs of anaemia, particularly in the first few months of treatment.
  • Do Not Abruptly Discontinue: Do not stop taking Bosentale-62.5 Tablet 10's suddenly, as this can cause a rapid and dangerous worsening of your pulmonary hypertension symptoms.

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Drug-Drug Interactions

  • Hormonal contraceptives (e.g., birth control pills, patches, vaginal rings, implants): Bosentale-62.5 Tablet 10's may reduce the effectiveness of these contraceptives, increasing the risk of an unplanned pregnancy.
  • Medicines used to suppress the immune system (e.g., Cyclosporine): Taking cyclosporine alongside Bosentale-62.5 Tablet 10's can significantly increase Bosentale-62.5 Tablet 10's levels in the blood, raising the risk of liver damage. This combination should be avoided.
  • Medicines used to treat diabetes (e.g., Glyburide): Combining glyburide with Bosentale-62.5 Tablet 10's may increase the risk of elevated liver enzymes and liver damage. This combination should be avoided.
  • Antifungal medicines (e.g., Ketoconazole): Taking ketoconazole with Bosentale-62.5 Tablet 10's may increase Bosentale-62.5 Tablet 10's levels in the body, potentially increasing the risk of side effects.
  • HIV medicines (e.g., Ritonavir): Ritonavir may increase the concentration of Bosentale-62.5 Tablet 10's in the bloodstream and may require dose adjustments or closer monitoring.
  • Antibiotics used to treat tuberculosis (e.g., Rifampin): Rifampin may decrease Bosentale-62.5 Tablet 10's levels in the blood, making the medicine less effective.

Drug-Food Interactions

  • Grapefruit and Grapefruit Juice: May interfere with how your body processes Bosentale-62.5 Tablet 10's, which can increase the level of medicine in your body and raise the risk of side effects.

Drug-Disease Interactions

  • Liver Disease: Do not take this medicine if you have moderate-to-severe liver impairment, as it can cause further liver damage.
  • Anaemia: If you have pre-existing low red blood cell levels, Bosentale-62.5 Tablet 10's may lower them further, requiring extra blood monitoring.
  • Fluid Retention or Heart Failure: This medicine can cause your body to retain fluid, which may worsen fluid buildup and place extra strain on a failing heart.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Bosentale-62.5 Tablet 10's is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentale-62.5 Tablet 10's can even enhance our physical fitness, delay disease progression, and improve quality of life.
Bosentale-62.5 Tablet 10's is an anti-hypertension medication primarily used to treat‚ pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin‚ narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentale-62.5 Tablet 10's helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.
Pulmonary arterial hypertension is a condition characterised by high pressure in the blood vessels that carry blood from the heart to the lungs. It can be due to constriction of blood vessels or some blockage in the blood vessel pathway.
Yes, in rare cases, $Name can cause anaemia. It can decrease your haemoglobin level, which may lead to anaemia. So, please regularly check your haemoglobin level if you are taking Bosentale-62.5 Tablet 10's.
It is usually taken with or without food. It should be swallowed as a whole with a glass of water; do not chew or crush it. Take it exactly as directed. Do not take more or less of it or more often than your doctor prescribes.
If you have liver problems, use Bosentale-62.5 Tablet 10's with caution and only under the guidance of your doctor. Patients with a history of liver disease should be closely monitored while taking Bosentale-62.5 Tablet 10's, as it may affect liver function. Your doctor may adjust the dosage or frequency of Bosentale-62.5 Tablet 10's based on your individual needs and medical condition.
No, you must not take Bosentale-62.5 Tablet 10's if you are pregnant or planning to become pregnant. This medicine can cause severe, life-threatening birth defects. If you suspect you are pregnant, stop taking the medication and contact your doctor immediately. Talk to your doctor for more information.
Common side effects of Bosentale-62.5 Tablet 10's may include swelling of legs and ankles, headaches, and diarrhoea in some cases. Most of these side effects of Bosentale-62.5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Store in a cool and dry place away from sunlight. Keep Bosentale-62.5 Tablet 10's out of the sight and reach of children.
You need monthly blood tests because this medicine can cause liver damage and lower your red blood cell count. Regular testing allows your doctor to monitor your liver health and blood levels to make sure the medicine is safe for you to continue. Talk to your doctor if you have questions about these tests.
No, hormonal contraceptives like birth control pills are not reliable on their own while taking Bosentale-62.5 Tablet 10's, as this medicine makes them less effective. You must use two reliable, non-hormonal methods of birth control at the same time. Talk to your doctor to choose the best options for you.
It can take several weeks of daily, consistent use before you notice an improvement in your breathing and exercise capacity. It is important to keep taking the medicine as prescribed even if you do not feel immediate benefits. Talk to your doctor if your symptoms do not improve.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can expand your blood vessels, which may worsen dizziness or low blood pressure, and it can also increase stress on your liver. Talk to your doctor about your alcohol use.
Swelling in your ankles, feet, or legs is a known side effect that indicates fluid retention. You should weigh yourself daily and report any sudden weight gain or worsening swelling to your doctor right away, as they may need to adjust your therapy. Talk to your doctor if you notice these changes.
No, you must not stop taking Bosentale-62.5 Tablet 10's suddenly, even if you feel completely fine. Stopping this medication abruptly can cause your pulmonary hypertension symptoms to return or worsen rapidly. Any changes to your dose must be guided gradually by your healthcare provider. Talk to your doctor before making any changes.
No, Bosentale-62.5 Tablet 10's does not cure pulmonary arterial hypertension, but it helps manage the condition by keeping blood vessels relaxed, improving your daily physical capabilities, and slowing down the progression of the disease. It is a long-term treatment. Talk to your doctor to understand your long-term treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

A-50, G. T. Karnal Road, Industrial Area Near Azadpur, Opposite Hans Cinema, Delhi- 110033, Delhi, India
Other Info - BOS0113
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