Brigrel Tablet 10's
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About Brigrel Tablet
Brigrel Tablet belongs to the class of medications called antiplatelet drugs, primarily used to reduce the risk of heart attack or stroke in high-risk patients. It is also used to lower the risk of blood clots in people with coronary artery disease.
Brigrel Tablet contains Ticagrelor, which works by preventing platelets from sticking together and forming a blood clot. Thereby, Brigrel Tablet helps reduce the risk of heart attack or stroke.
In some cases, Brigrel Tablet may cause side effects like bleeding, dyspnea (shortness of breath), dizziness, nausea, and diarrhoea. If any of these side effects persist or worsen, consult your doctor.
Do not take Brigrel Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health conditions and medications to prevent any potential interactions.
Uses of Brigrel Tablet
Brigrel Tablet is used to reduce the risk of blood clots, heart attack, or stroke in high-risk patients. The detailed uses of Brigrel Tablet are as follows:
- Prevents heart attack and stroke: Helps lower the risk of future heart attacks and strokes, especially in patients with a history of heart attack or blocked arteries.
- Prevents blood clots: Lowers the formation of blood clots by preventing the platelets from sticking together.
- Enhanced effect with aspirin: Commonly used with low-dose aspirin to enhance its protective effect against clot-related events.
Overview of Brigrel Tablet 10's
Understanding Brigrel Tablet 10's
Usage & Safety
Health Queries
I was diagnosed with unstable angina in 2002 and now have hypertension and occasional palpitations. What precautions or treatment should I follow?
Dr S Aneela
M. Pharm (Pharmacology)., PhD
I have a history of CAD with PTCA in 2012 and 2013 and unstable angina. What are my next treatment options?
Dr S Aneela
M. Pharm (Pharmacology)., PhD
Could you please advise me? I had a mild heart attack a few weeks ago and have been diagnosed with coronary artery disease and unstable angina.
Dr S Aneela
M. Pharm (Pharmacology)., PhD
He is a heart patient who underwent angioplasty, but still feels pain near the sternum. What could be the cause?
Dr S Aneela
M. Pharm (Pharmacology)., PhD
Have a query?
Directions for Use
- Brigrel Tablet can be taken with or without food, as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Brigrel Tablet as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
- Brigrel Tablet lowers the risk of heart attacks, strokes, and cardiovascular death in patients with a prior history of heart attack or who have blocked arteries.
- It helps prevent the formation of harmful blood clots, especially in patients with coronary artery disease (CAD) who have undergone stent placement.
- Brigrel Tablet also reduces the risk of a first heart attack or stroke in individuals with reduced blood flow to the heart (stable coronary artery disease).
- It decreases the risk of stroke and death in adults with narrowed or blocked arteries supplying blood to the brain.
- Brigrel Tablet is usually prescribed along with low-dose aspirin for better prevention of clot-related events.
How Brigrel Tablet Works
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- Tell your doctor immediately if you experience shortness of breath after taking medication.
- Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
- Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
- For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
- Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
- Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
- Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
- If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
- Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
- If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
- Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
- Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
- Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
- Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
- If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
- Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
- As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
- Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
- Take regular breaks to sit or lie down if you need to stand for long periods.
- When lying down, elevate your head with extra pillows to help improve blood flow.
- Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
- Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
- If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
- Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
- Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
- Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
- Gently massage the swollen area with firm but not painful pressure.
- Keep the swollen area clean and moisturized to prevent injury and infection.
- Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
- If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
- Talk to your doctor about your back pain and potential medication substitutes or dose changes.
- Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
- To lessen the tension on your back, sit and stand upright and maintain proper posture.
- To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
- Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
- Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
- To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
- Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
- Back discomfort can worsen by bending, twisting, and heavy lifting.
- Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
What if I have taken an overdose of Brigrel Tablet
Drug Warnings
- Do not take Brigrel Tablet if you are allergic to any of its components or have a history of bleeding in the brain.
- Inform your doctor if you have/had bleeding problems, serious injury or surgery, stomach ulcers, colon polyps, asthma, COPD (chronic obstructive pulmonary disease), liver problems, stroke, or are due to undergo any surgery.
- Consult your doctor if you are pregnant or plan to become pregnant. Your doctor will decide if it is safe to use Brigrel Tablet during pregnancy or not.
- Brigrel Tablet is not recommended during breastfeeding as it passes into the breast milk. Your doctor will decide if you will take Brigrel Tablet or breastfeed.
- The safety and effectiveness in children below 18 years of age have not been established, so Brigrel Tablet should not be given to children.
- Seek immediate medical attention if you notice signs of bleeding, such as uncontrollable bleeding, severe bleeding, pink/red/brown urine, vomit that looks like coffee grounds, blood in vomit, red/black stools, or coughing up blood.
- Brigrel Tablet may cause shortness of breath. Call your doctor if you experience new or unexpected shortness of breath at rest, at night, or during any activity.
Drug-Drug Interactions
Drug-Drug Interactions
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The blood levels and effects of Brigrel Tablet may be greatly increased when combined with itraconazole.
How to manage the interaction:
Itraconazole and Brigrel Tablet may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
Co-administration of posaconazole with Brigrel Tablet can increase the risk of bleeding.
How to manage the interaction:
Taking Brigrel Tablet with Posaconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using Brigrel Tablet together with Voriconazole can significantly increase the blood levels of Brigrel Tablet.
How to manage the interaction:
Taking Brigrel Tablet with Voriconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Taking Brigrel Tablet with Ritonavir may significantly increase the blood levels of Brigrel Tablet.
How to manage the interaction:
Taking Brigrel Tablet with Ritonavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using Brigrel Tablet together with indinavir can cause risk of bleeding.
How to manage the interaction:
Taking Brigrel Tablet with Indinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using Brigrel Tablet together with telithromycin cause increase the blood levels of Brigrel Tablet.
How to manage the interaction:
Taking Brigrel Tablet with Telithromycin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Co-administration of Brigrel Tablet with ketoconazole can cause severe bleeding.
How to manage the interaction:
Taking Brigrel Tablet with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Mifepristone with Brigrel Tablet can increase the risk of vaginal bleeding in women.
How to manage the interaction:
Taking Brigrel Tablet with Mifepristone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
Co-administration of Brigrel Tablet with Conivaptan can increase the risk of bleeding.
How to manage the interaction:
Taking Brigrel Tablet with Conivaptan is not recommended, please consult your doctor before taking it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Brigrel Tablet with Rifampicin may significantly reduce the blood levels of Brigrel Tablet, which may make the medication less effective.
How to manage the interaction:
Taking Rifampicin with Brigrel Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Reducing weight and having a healthy BMI are very important in enhancing cardiac health.
- 30 minutes of daily physical exercise can go a long way in preventing heart disease.
- Avoid smoking to improve cardiac health.
- Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits.
- Reducing stress is crucial for maintaining a healthy heart. Try yoga and meditation for a relaxed state of mind.
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Alcohol
Safe if prescribed
It is unsafe to consume alcohol since it may worsen the side effects, such as dizziness.
Pregnancy
Consult your doctor
Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Brigrel Tablet may pass into breast milk and may cause side effects in a breastfed child. Please consult your doctor before starting Brigrel Tablet .
Driving
Safe if prescribed
Do not drive or operate machinery if you experience dizziness or drowsiness while using Brigrel Tablet .
Liver
Consult your doctor
Let your doctor know if you had or have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Brigrel Tablet . However, Brigrel Tablet is not recommended in patients with severe liver problems.
Kidney
Consult your doctor
Let your doctor know if you had or have any history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Brigrel Tablet . However, Brigrel Tablet is not recommended in patients with severe kidney problems.
Children
Safe if prescribed
Brigrel Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Brigrel Tablet have not been established in children.
Heart
Brigrel Tablet is safe for use in heart patients if recommended by the physician.
Geriatrics
Consult your doctor
Brigrel Tablet should be used under extreme caution in geriatric patients. Please consult your physician.
FAQs
Brigrel Tablet is primarily used to prevent heart attack or stroke in people at high risk of heart disease. It‚ helps to prevent blood clots in people with acute coronary syndrome (the heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart.
Brigrel Tablet contains Ticagrelor, which works by preventing platelets from sticking together and forming a blood clot.
Yes, taking Brigrel Tablet can increase the risk of bleeding. So, please be very cautious while cutting fingernails or toenails, shaving, or using sharp objects to avoid bleeding.
Please consult your doctor if you are due to undergo any surgery. The doctor might ask you to stop taking Brigrel Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.
There might be a problem if you take herbal therapies with Brigrel Tablet , especially those that affect blood, like Ginkgo Biloba, Grapefruits, St John's wort plant extract used as an antidepressant. Taking these can increase your risk of bleeding. Tell your doctor if you are using any herbal supplements before taking Brigrel Tablet .
Brigrel Tablet may cause shortness of breath, making it difficult to breathe in people with asthma or COPD. Hence, it should be used with caution. Please consult your doctor if you have asthma or breathing problems.
Do not drink grapefruit juice while taking Brigrel Tablet . Grapefruit juice may increase the blood-thinning effect of the medicine.
Brigrel Tablet contains ticagrelor, which, when taken with clopidogrel, may increase the risk of bleeding. Consult the doctor before taking other medicines with Brigrel Tablet .
Brigrel Tablet should not be discontinued without a doctor's consultation. Stopping Brigrel Tablet might increase the risk of a heart attack or stroke.
Brigrel Tablet may cause blood in urine. Consult the doctor if you experience this.
Brigrel Tablet might lower the blood pressure. Let the doctor know if you are taking anti-hypertensives (blood pressure-lowering medicines). Regular monitoring of blood pressure levels is advised.
Brigrel Tablet can be taken with other medicines if prescribed by the doctor. Before starting Brigrel Tablet inform the doctor if you are taking any other medicines to prevent interactions.
Brigrel Tablet is an antiplatelet medicine which inhibits the aggregation of platelets that may cause a heart attack or stroke.
Limit alcohol consumption with Brigrel Tablet as it might increase the risk of bleeding.
Brigrel Tablet may cause significant, sometimes fatal bleeding. Inform the doctor if you have/had a condition that causes you to bleed more easily than normal; bleeding in your stomach, intestines, or brain; a stomach ulcer; polyps (abnormal growths in the lining of the large intestine); a stroke or mini-stroke; or liver disease. Seek immediate medical attention if you experience unexplained, severe, long-lasting, or uncontrollable bleeding; red or black, tarry stools; pink or brown urine; vomit that is bloody or that looks like coffee grounds; or coughing up blood or blood clots.
Brigrel Tablet works within 30 minutes of taking the first dose.
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