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compositionComposition:BRINZOLAMIDE-1%W/V
prescription
Prescription Medicine
info
Brinzagan Ophthalmic Suspension 5 ml
Brinzagan Ophthalmic Suspension 5 ml
Brinzagan Ophthalmic Suspension 5 ml

Brinzagan Ophthalmic Suspension 5 ml is used to treat increased pressure in eye conditions. It contains Brinzolamide, which lowers the raised pressure in the eye by reducing aqueous humour entry into the eyeball. In some cases, you may experience side effects such as eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BRINZOLAMIDE-1%W/V

Manufacturer/Marketer :

Allergan Healthcare India Pvt Ltd

Consume Type :

Ophthalmic

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Brinzagan Ophthalmic Suspension 5 ml

Brinzagan Ophthalmic Suspension 5 ml is a prescription eye drop designed to lower elevated pressure inside the eyes. It is primarily used to treat patients with open-angle glaucoma or ocular hypertension, conditions that can cause damage to the optic nerve if left untreated. By managing this pressure, the medication helps protect and preserve your eyesight.

To get the best results, you must use Brinzagan Ophthalmic Suspension 5 ml consistently and exactly as directed by your healthcare provider. It is applied directly to the affected eye, and keeping a regular daily schedule is crucial for maintaining stable eye pressure. Incorporating regular eye check-ups and avoiding eye strain can also support your overall treatment plan.

While using this medication, some people may experience mild, temporary side effects like temporary blurred vision or a bitter taste in the mouth. However, if you experience more serious issues, such as severe eye irritation, pain, or signs of an allergic reaction, you should contact your doctor immediately.

Do not use this medicine if you have severe kidney disease or a known allergy to sulfa-based medications. Before starting Brinzagan Ophthalmic Suspension 5 ml, tell your doctor about any pre-existing health conditions, especially if you have liver problems, dry eye syndrome, or corneal issues.

It is important to discuss potential interactions with your doctor, especially if you take other eye medications or oral carbonic anhydrase inhibitors. If you are pregnant, breastfeeding, or managing health conditions as an elderly individual, consult your doctor or pharmacist before starting this treatment to ensure it is safe for your specific situation.

Uses of Brinzagan Ophthalmic Suspension 5 ml

Brinzagan Ophthalmic Suspension 5 ml is used to lower increased pressure inside the eye. It is commonly prescribed for:

  • Open-angle glaucoma: Brinzagan Ophthalmic Suspension 5 ml helps reduce high fluid pressure inside the eye, which prevents progressive damage to the optic nerve and helps safeguard your vision from worsening.
  • Ocular hypertension: Brinzagan Ophthalmic Suspension 5 ml lowers elevated pressure in eyes that do not show signs of glaucoma, reducing the risk of developing future optic nerve damage.
     

Key Benefits

Brinzagan Ophthalmic Suspension 5 ml helps lower increased pressure inside the eye, reducing the risk of vision loss associated with glaucoma and ocular hypertension. Regular use helps protect the optic nerve and preserve eyesight.

  • Lowers Eye Pressure: Helps reduce elevated pressure inside the eye by decreasing fluid production.
  • Helps Protect Vision: Reduces the risk of progressive optic nerve damage and vision loss associated with glaucoma.
  • Provides Targeted Treatment: Works directly inside the eye with minimal absorption into the rest of the body.
  • Supports Long-Term Eye Health: Regular use helps maintain stable eye pressure throughout the day and night.
  • Preserves Quality of Life: By helping protect vision, it supports continued independence and the ability to perform everyday activities.
     
Side effects of Brinzagan Ophthalmic Suspension 5 ml
  • Bitter or bad taste can be managed by taking Vitamin B12 supplements only after your doctor's consultation.
  • Maintain good oral hygiene by using mouthwash frequently and cleaning your tongue while brushing.
  • Avoid eating foods that cause heartburn or stomach pain, as they can lead to a bitter taste in your mouth.
  • Do not smoke or drink alcohol, as it can worsen your condition.
  • Gently wash the eyelids using mild soap with lukewarm water to wash away dirt and bacteria.
  • Avoid rubbing the eyes or eyelids to prevent the inflammation.
  • Keep contact lenses clean and disinfected to avoid infection.
  • Follow the treatment plan and attend follow-up appointments to ensure full recovery.
  • See a doctor again if changes in your vision or eye symptoms occur.
  • Know your allergens that cause dermatitis and avoid them.
  • Use fragrance-free detergents and soaps.
  • Apply moisturizer after taking bath to retain moisture in the skin.
  • Apply cool, moist compresses to the rash.
  • Talk to your doctor about creams and ointments to manage your dermatitis.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Excessive blood flow needs immediate medical attention it should not be ignored.
  • Get an immediate physical examination and take necessary precautions.
  • Avoid anxiety and stress, as it can worsen your condition.
  • Consume more foods that are rich in Vitamin C and iron.
  • Stay hydrated and take necessary medication to control excess bleeding, as it can lead to critical conditions.
  • Wash your hands thoroughly before touching your eyes to prevent spreading the infection.
  • Gently wipe away discharge from the inner corner of your eye outwards using a clean, damp washcloth.
  • Apply warm compress to help loosen crusty build up and soothe irritation.
  • Take diet containing vitamins, minerals and proteins for the eye health.
  • Consult the doctor if the conjunctival discharge is excessive with severe pain.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
  • Avoid touching the tip of the container to prevent contamination.

How Brinzagan Ophthalmic Suspension 5 ml Works

Brinzagan Ophthalmic Suspension 5 ml contains brinzolamide, which belongs to a group of medications called carbonic anhydrase inhibitors. Inside the eye, a clear fluid called aqueous humour is constantly being produced and drained to maintain the eye's shape and health. When too much of this fluid is produced, or if it does not drain properly, the pressure inside the eye builds up, which can damage your vision. This medicine works by blocking a specific enzyme in the eye called carbonic anhydrase, which is responsible for producing this fluid. By slowing down the activity of this enzyme, Brinzagan Ophthalmic Suspension 5 ml reduces the amount of fluid created in the eye. This drop in fluid production successfully lowers the internal eye pressure, protecting your optic nerve from damage.
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Alcohol

Consult your doctor

The interaction of alcohol with Brinzagan Ophthalmic Suspension 5 ml is unknown. Please consult a doctor before consuming alcohol with Brinzagan Ophthalmic Suspension 5 ml.

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Pregnancy

Caution

Brinzagan Ophthalmic Suspension 5 ml is a Category C pregnancy drug and is not recommended for use during pregnancy unless your doctor considers it essential.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Brinzagan Ophthalmic Suspension 5 ml. Please talk to your doctor before using Brinzagan Ophthalmic Suspension 5 ml in breastfeeding mothers.

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Driving

Caution

Brinzagan Ophthalmic Suspension 5 ml may cause blurred vision in some people. So, drive only when your vision is clear after taking Brinzagan Ophthalmic Suspension 5 ml.

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Liver

Caution

Brinzagan Ophthalmic Suspension 5 ml should be used with caution in patients who have liver problems. If you have any concerns about its use, please talk to your doctor.

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Kidney

Caution

Brinzagan Ophthalmic Suspension 5 ml should be used with caution in patients who have kidney problems. If you have any concerns about its use, please talk to your doctor.

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Children

Unsafe

Brinzagan Ophthalmic Suspension 5 ml is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please consult your doctor before using Brinzagan Ophthalmic Suspension 5 ml if you have pre-existing heart problems. Your doctor will prescribe Brinzagan Ophthalmic Suspension 5 ml if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Brinzagan Ophthalmic Suspension 5 ml to geriatric patients. Your doctor will prescribe Brinzagan Ophthalmic Suspension 5 ml if the benefits outweigh the risks.

What if I have taken an overdose of Brinzagan Ophthalmic Suspension 5 ml

If you accidentally put too many drops in your eye, flush it thoroughly with plenty of warm water. If the eye drops are accidentally swallowed, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Attend Regular Eye Check-Ups: Keep all scheduled eye appointments so your doctor can monitor your eye pressure and assess the health of your optic nerve.
  • Avoid Heavy Straining: Avoid heavy lifting and activities that involve prolonged straining or keeping your head below your body, as these may temporarily increase eye pressure.
  • Limit Excessive Caffeine: Reduce the intake of highly caffeinated drinks, as large amounts of caffeine may cause a temporary rise in eye pressure.
  • Drink Fluids Gradually: Drink moderate amounts of fluids throughout the day instead of consuming large volumes at once.
  • Protect Your Eyes: Wear protective eyewear during sports, gardening, or home improvement work to reduce the risk of eye injuries.
     

Have a query?

How Soon It Starts Working

  • The time required for Brinzagan Ophthalmic Suspension 5 ml to start to work: The time required for Brinzagan Ophthalmic Suspension 5 ml to show its action is not clinically established.
  • The time for which the effects of Brinzagan Ophthalmic Suspension 5 ml last: The duration of action for Brinzagan Ophthalmic Suspension 5 ml is not clinically established.

What if you forget to take Brinzagan Ophthalmic Suspension 5 ml

If you miss a dose, apply the eye drop as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular routine. Do not apply a double dose to make up for a missed one.

Storage

•Store Brinzagan Ophthalmic Suspension 5 ml at room temperature, keeping it between 4°C and 30°C (39°F to 86°F). •Do not freeze this medication, and keep it away from direct heat and bright light.

Drug Warnings

  • Shake Well Before Use: Shake the bottle thoroughly before each application to ensure the medicine is evenly mixed.
  • Avoid Contaminating the Dropper: Do not touch the dropper tip to your eye, eyelid, fingers, or any surface to reduce the risk of infection.
  • Use Caution After Application: Your vision may become temporarily blurred after using the drops. Avoid driving or operating machinery until your vision is clear.
  • Separate Different Eye Drops: If using more than one eye medication, wait at least 5 to 10 minutes between each eye drop.
  • Remove Contact Lenses: Take out soft contact lenses before applying Brinzagan Ophthalmic Suspension 5 ml and wait at least 15 minutes before reinserting them.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Some medicines may affect how Brinzagan Ophthalmic Suspension 5 ml works or increase the risk of side effects. Tell your doctor about all the medicines you are taking, including:

  • Oral carbonic anhydrase inhibitors: Taking these oral medications while using Brinzagan Ophthalmic Suspension 5 ml eye drops may increase the risk of systemic side effects, as both belong to the same drug class.
  • High-dose aspirin: May interact with this medicine and increase the risk of side effects, so discuss its use with your doctor.

Drug-Disease Interactions

Certain medical conditions may affect how Brinzagan Ophthalmic Suspension 5 ml works or increase the risk of side effects. Inform your doctor if you have any of the following conditions before starting treatment.

  • Severe kidney disease: Do not use this medicine if you have severe kidney impairment, as it may build up in your body and cause adverse effects.
  • Severe liver damage: Use with caution, as safety data is limited for individuals with severe liver issues.
  • Sulfonamide allergy: Do not use this medicine if you have a known allergy to sulfa drugs, as severe, potentially life-threatening allergic reactions can occur.
     
BrinzolamideSalsalate
Severe
BrinzolamideSodium salicylate
Severe

Drug-Drug Interactions

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BrinzolamideSalsalate
Severe
How does the drug interact with Brinzagan Ophthalmic Suspension 5 ml:
Concomitant use of Brinzagan Ophthalmic Suspension 5 ml with salsalate can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brinzagan Ophthalmic Suspension 5 ml should be used with salsalate only if prescribed by the doctor. Consult a doctor immediately if you experience ringing in the ears, vomiting, headache, dizziness, and fever. Do not stop using any medications without first talking to your doctor.
BrinzolamideSodium salicylate
Severe
How does the drug interact with Brinzagan Ophthalmic Suspension 5 ml:
Concomitant use of Brinzagan Ophthalmic Suspension 5 ml with sodium salicylate may cause ringing in the ears, nausea, vomiting, headache, dizziness, confusion, hallucinations, rapid breathing, fever, and seizure (convulsions).

How to manage the interaction:
Although there is an interaction, Brinzagan Ophthalmic Suspension 5 ml should be used with sodium salicylate only if prescribed by the doctor. However, if you experience ringing in the ears, vomiting, headache, dizziness, or fever, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
BrinzolamideCholine salicylate
Severe
How does the drug interact with Brinzagan Ophthalmic Suspension 5 ml:
Taking Brinzagan Ophthalmic Suspension 5 ml with Choline salicylate may increase the risk of side effects.

How to manage the interaction:
Although taking Brinzagan Ophthalmic Suspension 5 ml and Choline salicylate together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
BrinzolamideAspirin
Severe
How does the drug interact with Brinzagan Ophthalmic Suspension 5 ml:
Coadministration of Brinzagan Ophthalmic Suspension 5 ml with Aspirin may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and Brinzagan Ophthalmic Suspension 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
BrinzolamideDiflunisal
Severe
How does the drug interact with Brinzagan Ophthalmic Suspension 5 ml:
Coadministration of Brinzagan Ophthalmic Suspension 5 ml with diflunisal can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brinzagan Ophthalmic Suspension 5 ml should be used with diflunisal only if prescribed by the doctor. Consult a doctor if you experience vomiting, headache, dizziness, or fever. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIGLAUCOMA AGENTS]

FAQs

Brinzagan Ophthalmic Suspension 5 ml is used to treat glaucoma (open-angle type) and ocular hypertension (high eye pressure).
Brinzagan Ophthalmic Suspension 5 ml contains Brinzolamide that works by inhibiting the action of carbonic anhydrase enzyme and decreases bicarbonate production, which is essential for the production of aqueous humour. Thereby, it reduces the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) and lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.
You are recommended to wash your hands first and tilt your head back, and gently pull the lower eyelid downwards. Then, press the bottom of the bottle gently by holding it upside down to instill one drop into the affected eye without touching the tip of the bottle to the eye or surrounding areas in order to avoid contamination. Finally, replace the cap tightly after use. After applying Brinzagan Ophthalmic Suspension 5 ml, you are advised to apply to the corner of the eye by pressing a finger to stop eye drops from spreading into the rest of the body.
No, you are not recommended to wear contact lenses while using Brinzagan Ophthalmic Suspension 5 ml as it may contain a preservative that changes the colour of the contact lens, as it may be absorbed by a soft contact lens. Therefore, you are advised to remove contact lenses before applying Brinzagan Ophthalmic Suspension 5 ml and reinsert after 15 minutes of using Brinzagan Ophthalmic Suspension 5 ml.
You are recommended to maintain a minimum of 5 minutes time gap between using Brinzagan Ophthalmic Suspension 5 ml and other eye drops and administer eye ointments in the last.
Yes, Brinzagan Ophthalmic Suspension 5 ml may cause temporary blurred vision. Therefore, you are recommended to wait until your vision is clear before driving or operating heavy machinery.
Brinzagan Ophthalmic Suspension 5 ml should be used as prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Brinzagan Ophthalmic Suspension 5 ml may cause a headache as a side effect. Rest in a quiet/dark room, massage gently, and use a hot/cold compress on the head and neck.
Brinzagan Ophthalmic Suspension 5 ml may cause side effects like eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. If the side effects worsen or persist, please consult your doctor.
This happens because the eye drops can drain from your eye through the tear ducts into your nose and throat. To minimise this, gently press the inner corner of your eye next to your nose for 1 to 2 minutes right after putting in the drops. Talk to your doctor if this taste remains highly bothersome.
The safety of Brinzagan Ophthalmic Suspension 5 ml during pregnancy has not been fully established. It should only be used if your doctor decides the benefits outweigh the potential risks to the baby. Talk to your doctor or pharmacist to discuss your options.
No, you should not stop using Brinzagan Ophthalmic Suspension 5 ml without consulting your healthcare provider. High eye pressure often has no symptoms, and stopping the drops can cause your eye pressure to rise again, potentially damaging your vision. Talk to your doctor before making any changes.
No, Brinzagan Ophthalmic Suspension 5 ml does not cure glaucoma. It works by managing and lowering the pressure inside your eye to prevent further damage to your optic nerve and protect your sight. It must be used long-term as directed. Talk to your doctor for more details.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No.3, Kasturba Road, Level 2, Prestige Obelisk, Bangalore – 560 001., KARNATAKA, INDIA
Other Info - BRI0390

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