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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Brivasure Oral Solution is used to treat partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits) in patients one month of age and older. It contains Brivaracetam, which decreases the brain's excessive and abnormal nerve activity and thus controls seizures. It may cause common side effects such as excessive sleepiness, dizziness, overtiredness, nausea and vomiting.

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Composition :

BRIVARACETAM-10MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Brivasure Oral Solution

Brivasure Oral Solution is used for treating partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits) in patients one month of age and older. Partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere. Common symptoms are involuntary muscle contractions, followed by relaxation on one side of the body, uncontrolled head or eye movements, rapid heart rate, and a tingling sensation on the skin.

Brivasure Oral Solution contains '‘Brivaracetam' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivasure Oral Solution decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.

Brivasure Oral Solution should be used as prescribed by the doctor. In some cases, you may experience certain common side effects such as somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Brivasure Oral Solution for as long as your doctor has prescribed. Brivasure Oral Solution should be gradually withdrawn, so please do not stop taking Brivasure Oral Solution without consulting your doctor. Before taking the Brivasure Oral Solution , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies. It is recommended not to drive or operate machinery as Brivasure Oral Solution may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy.

Uses of Brivasure Oral Solution

Brivasure Oral Solution is used in the treatment of Partial-onset seizures.

Directions for Use

• Take Brivasure Oral Solution with or without food or as advised by a doctor.• Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness. • Swallow it as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Brivasure Oral Solution belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat partial-onset seizures in people with epilepsy (fits). Brivasure Oral Solution consists of Brivaracetam, which works by reducing the electrical impulses and subsequent firing of the nerve impulses that cause fits. Brivasure Oral Solution decreases the excessive and abnormal nerve activity in the brain, thereby helping in controlling seizures.

Storage

Keep Brivasure Oral Solution out of the sight and reach of children.
Side effects of Brivasure Oral Solution 100 ml
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Brivasure Oral Solution

Do not take more than the prescribed dose of Brivasure Oral Solution as it may cause overdose. The symptoms of overdose include vertigo, nausea, fatigue (overtired), balance disorder, anxiety, double vision and slow heart rate. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking the Brivasure Oral Solution , inform your doctor about all your medical conditions, allergic conditions, and all medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. If you become pregnant while taking Brivasure Oral Solution , call your doctor. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies or feel it worsens your condition. It is recommended not to drive or operate machinery as Brivasure Oral Solution may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy. Do not stop Brivasure Oral Solution without first talking to a healthcare provider. Stopping the usage of Brivasure Oral Solution suddenly can cause serious problems. Sometimes, it may lead to seizures that will not stop (status epilepticus).

Drug-Drug Interactions

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BrivaracetamEsketamine
Severe

Drug-Drug Interactions

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BrivaracetamEsketamine
Severe
How does the drug interact with Brivasure Oral Solution 100 ml:
Co-administration of Brivasure Oral Solution 100 ml with Esketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is an interaction, Brivasure Oral Solution 100 ml can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you notice drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue the medication without consulting a doctor
How does the drug interact with Brivasure Oral Solution 100 ml:
Co-administration of Brivasure Oral Solution 100 ml with Ketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction between Brivasure Oral Solution 100 ml and Ketamine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - make sure to contact adoctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Brivasure Oral Solution 100 ml:
Brimonidine may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of Brivasure Oral Solution 100 ml with brimonidine may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction Brivasure Oral Solution 100 ml can be taken with brimonidine if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving the Brivasure Oral Solution if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Brivasure Oral Solution in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Brivasure Oral Solution ; your doctor will decide whether breastfeeding mothers can take Brivasure Oral Solution .

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Driving

Unsafe

Brivasure Oral Solution may cause somnolence (excess sleepiness) and fatigue (feeling overtired). These symptoms impact daily activities; hence, avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Dose adjustments may be needed. So inform your doctor before receiving the Brivasure Oral Solution if you have a history of liver impairments.

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Kidney

Caution

Brivasure Oral Solution is not recommended for use in end-stage renal disease patients undergoing dialysis. If you have a history of kidney diseases/conditions, inform your doctor before receiving the Brivasure Oral Solution .

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Children

Safe if prescribed

Your doctor will prescribe only if the benefits outweigh the risks.

Have a query?

FAQs

Brivasure Oral Solution is used for treating partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits).

Brivasure Oral Solution contains Brivaracetam, an antiepileptic that attaches itself to specific sites (SV2A) on nerve cell surfaces. This activity may suppress the brain's abnormal activity and prevents the spread of electrical signals that cause seizures.

No, Brivasure Oral Solution should not be stopped even if you start feeling better. Suddenly stopping the Brivasure Oral Solution may cause continuous seizures, which can be difficult to control. To treat your condition effectually, continue taking Brivasure Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivasure Oral Solution , your doctor will gradually reduce the dose to avoid precipitating seizures.

Brivasure Oral Solution may cause suicidal thoughts such as killing or harming yourself. People taking Brivasure Oral Solution should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.

Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.

In rare cases, Brivasure Oral Solution may cause behavioural reactions, including psychotic symptoms, irritability, depression, aggressive behaviour, and anxiety. If you experience such symptoms, report to the doctor immediately.

Consult the doctor if you do not see an improvement. Do not discontinue Brivasure Oral Solution without consulting your doctor as stopping the medicine may cause your seizures to return or occur more often.

Brivasure Oral Solution should be avoided by people who are allergic to any of its components.

Brivasure Oral Solution should be swallowed as a whole with water; do not crush or chew it.

Side effects of Brivasure Oral Solution are somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea and vomiting. Talk to your doctor if you experience these side effects persistently.

Country of origin

INDIA

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - BRI0613

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