Bunase-L 0.5 mg Respule 5 x 2 ml is a combination medication primarily used to prevent or treat symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Bunase-L 0.5 mg Respule 5 x 2 ml is a combination of two drugs, namely: Levosalbutamol (bronchodilator) and Budesonide (corticosteroid). Levosalbutamol belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier. Budesonide belongs to the class of corticosteroids that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, it provides relief from sneezing, runny or blocked nose, and sinus discomfort.

Bunase-L 0.5 mg Respule 5 x 2 ml is for inhalation only. Use Bunase-L 0.5 mg Respule 5 x 2 ml as advised by your doctor. Your doctor will advise you how often you take Bunase-L 0.5 mg Respule 5 x 2 ml based on your medical condition. Some people may experience fungal infection in the mouth, headache, sore throat, hoarse voice, back pain, fast heartbeat, muscle cramps, or shaking. Most of these side effects of Bunase-L 0.5 mg Respule 5 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to lactose, Bunase-L 0.5 mg Respule 5 x 2 ml, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Bunase-L 0.5 mg Respule 5 x 2 ml. Bunase-L 0.5 mg Respule 5 x 2 ml is not recommended for children below 6 years of age. Avoid contact with people who have infections or who are sick as Bunase-L 0.5 mg Respule 5 x 2 ml may weaken the immune system causing infections easily. If you have Lapp lactase deficiency, galactose intolerance or glucose-galactose malabsorption, high blood pressure, diabetes, hypokalemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, hyperthyroidism (overactive thyroid), tuberculosis, stomach ulcer, eczema, heart or liver problems, inform your doctor before taking Bunase-L 0.5 mg Respule 5 x 2 ml.

Bunase-L 0.5 mg Respule 5 x 2 ml contains Levosalbutamol and Budesonide which are used to prevent or treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). Levosalbutamol is a bronchodilator that relaxes muscles and widens the airways of the lungs. Thus, it makes breathing easier. Budesonide is a corticosteroid that acts inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, it provides relief from sneezing, runny or blocked nose, and sinus discomfort.

• Fungal infection in the mouth
• Headache
• Sore throat
• Hoarse voice
• Back pain
• Fast heartbeat
• Muscle cramps
• Shaking

If you are allergic to lactose, Bunase-L 0.5 mg Respule 5 x 2 ml, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Bunase-L 0.5 mg Respule 5 x 2 ml. Bunase-L 0.5 mg Respule 5 x 2 ml is not recommended for children below 6 years of age. If wheezing or chest tightness worsens, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Bunase-L 0.5 mg Respule 5 x 2 ml as it may cause low potassium levels in the blood. Avoid contact with people who have infections or who are sick as Bunase-L 0.5 mg Respule 5 x 2 ml may weaken the immune system causing infections easily. If you have Lapp lactase deficiency, galactose intolerance or glucose-galactose malabsorption, high blood pressure, diabetes, hypokalemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, hyperthyroidism (overactive thyroid), tuberculosis, stomach ulcer, eczema, heart or liver problems, inform your doctor before taking Bunase-L 0.5 mg Respule 5 x 2 ml.

Drug-Drug Interaction: Bunase-L 0.5 mg Respule 5 x 2 ml may interact with bronchodilators (formoterol, salmeterol, arformoterol), steroids (prednisone), water pills (furosemide), pain killers (aspirin, ibuprofen), antibiotic (azithromycin), antidepressant (duloxetine), laxative (polyethylene glycol 3350), medicines used to lower high blood pressure (metoprolol), central nervous system stimulants (amphetamine).

Drug-Food Interaction: Bunase-L 0.5 mg Respule 5 x 2 ml may interact with grapefruit and grapefruit juice. Therefore, avoid intake of grapefruit or its juice with Bunase-L 0.5 mg Respule 5 x 2 ml as it may lead to severe adverse effects.

Drug-Disease Interaction: If you have Lapp lactase deficiency, galactose intolerance or glucose-galactose malabsorption, high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, hyperthyroidism (overactive thyroid), tuberculosis, stomach ulcer, eczema, heart or liver problems, inform your doctor before taking Bunase-L 0.5 mg Respule 5 x 2 ml.

• FORMOTEROL
• SALMETEROL
• ARFORMOTEROL
• PREDNISONE
• FUROSEMIDE
• ASPIRIN
• AZITHROMYCIN
• DULOXETINE
• POLYETHYLENE GLYCOL
• METOPROLOL
• AMPHETAMINE
• IBUPROFEN

• Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
• Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice as it may worsen asthma symptoms.
• Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
• Quit smoking as it may reduce the effectiveness of the Bunase-L 0.5 mg Respule 5 x 2 ml and irritate the lungs worsening breathing problems.
• Learning breathing exercises will help you move more air in and out of your lungs.

You are advised to rinse your mouth with water after each dose of Bunase-L 0.5 mg Respule 5 x 2 ml because it not only removes the taste of medicine inhaled but also helps to avoid fungal infections in the mouth and throat. After rinsing your mouth thoroughly, you may drink water, milk or any liquids.

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).