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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Buprigesic 10mcg/Hr Transdermal Patch is primarily used to treat pain. It contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain that is responsible for causing pain. This provides pain relief by acting on specific receptors in the brain. Common side effects of Buprigesic 10mcg/Hr Transdermal Patch are drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness, or tiredness.

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rxMedicinePrescription drug

Whats That

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Synonym :

BUPRENORPHINE HCL, BUPRENORPHINE HYDROCHLORIDE

Composition :

BUPRENORPHINE-10MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Buprigesic 10mcg/Hr Transdermal Patch

Buprigesic 10mcg/Hr Transdermal Patch belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Buprigesic 10mcg/Hr Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain.

Use Buprigesic 10mcg/Hr Transdermal Patch as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Buprigesic 10mcg/Hr Transdermal Patch should be avoided if you are allergic to it or any of its ingredients or opioids. Do not use Buprigesic 10mcg/Hr Transdermal Patch if you are pregnant or breastfeeding. Buprigesic 10mcg/Hr Transdermal Patch is not recommended for children below 18 years of age. Buprigesic 10mcg/Hr Transdermal Patch is a habit-forming drug; hence, there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Buprigesic 10mcg/Hr Transdermal Patch may decrease fertility in men and women. Do not consume alcohol while using Buprigesic 10mcg/Hr Transdermal Patch as it may increase the risk of side effects.

Uses of Buprigesic 10mcg/Hr Transdermal Patch

Buprigesic 10mcg/Hr Transdermal Patch is used in the treatment of Pain. The detailed use of Buprigesic 10mcg/Hr Transdermal Patch is as follows:<br/>• Manage chronic severe pain: Buprigesic 10mcg/Hr Transdermal Patch provides continuous pain relief for patients with persistent, moderate to severe pain who require long-term opioid therapy. It works by partially activating opioid receptors in the brain, altering pain perception without producing the full effects of stronger opioids.<br/>

Directions for Use

• Follow the timing and schedule given by your doctor.• Apply the patch to clean, dry, and hairless skin on the upper torso or upper arm. Press the patch firmly in place and ensure it sticks well.• Wash your hands after applying the patch to avoid accidental contact with your eyes or mucous membranes.• Do not cut, crush, or break the patch. Avoid applying the patch to broken, irritated, or oily skin.• Change the patch as instructed, and avoid wearing more than one patch at a time unless directed by your doctor.

Medicinal Benefits

The Buprigesic 10mcg/Hr Transdermal Patch contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Buprigesic 10mcg/Hr Transdermal Patch has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses.

How Buprigesic 10mcg/Hr Transdermal Patch Works

Buprigesic 10mcg/Hr Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain.

Storage

• Store in a cool and dry place away from sunlight.• Keep Buprigesic 10mcg/Hr Transdermal Patch out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Buprigesic 10mcg/Hr Transdermal Patch

Please do not exceed the recommended dose, as it might cause an overdose. The most common signs and symptoms of Buprigesic 10mcg/Hr Transdermal Patch are cold, clammy skin, extreme sleepiness or drowsiness, muscle weakness, narrowing or widening of the pupils (black circles in the center of the eye), slow or shallow breathing or difficulty breathing, slow heartbeat, unable to respond or wake up, and unusual snoring. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Please do not stop using Buprigesic 10mcg/Hr Transdermal Patch suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Buprigesic 10mcg/Hr Transdermal Patch or any other medicines, please tell your doctor. Do not use Buprigesic 10mcg/Hr Transdermal Patch if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Buprigesic 10mcg/Hr Transdermal Patch is not recommended for children below 18 years of age. Avoid consuming alcohol with Buprigesic 10mcg/Hr Transdermal Patch as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Buprigesic 10mcg/Hr Transdermal Patch should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants.

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Taking Ziprasidone with Buprigesic 10mcg/Hr Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Buprigesic 10mcg/Hr Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineAlvimopan
Critical
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using alvimopan together with Buprigesic 10mcg/Hr Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Buprigesic 10mcg/Hr Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using Buprigesic 10mcg/Hr Transdermal Patch together with other medications that also cause central nervous system it may lead to significant adverse effects (respiratory difficulties, and unconsciousness).

How to manage the interaction:
Concomitant administration of oxcarbazepine with Buprigesic 10mcg/Hr Transdermal Patch can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
The combination of Buprigesic 10mcg/Hr Transdermal Patch and midazolam can result in central nervous system depression (slowing of the body's neurological functioning).

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch along with Midazolam can result in an interaction. However, it can be taken if a doctor has advised it. If you experience any symptoms of breathing problems and unconsciousness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using arsenic trioxide together with Buprigesic 10mcg/Hr Transdermal Patch can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Arsenic trioxide with Buprigesic 10mcg/Hr Transdermal Patch together can result in an interaction, but it can be taken if a doctor has advised it. If you experience an irregular heart rhythm, a heart condition, a condition called congenital long qt syndrome, problems with your heart's electrical system, severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using Alprazolam together with Buprigesic 10mcg/Hr Transdermal Patch can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Alprazolam and Buprigesic 10mcg/Hr Transdermal Patch may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Taking Buprigesic 10mcg/Hr Transdermal Patch with carbozantinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch alongside carbozantinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Co-administration of Buprigesic 10mcg/Hr Transdermal Patch with tramadol may increase the risk and severity of the seizure.

How to manage the interaction:
Taking Buprigesic 10mcg/Hr Transdermal Patch with tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphineTrimethadione
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
When Buprigesic 10mcg/Hr Transdermal Patch is used with trimethadione, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch alongside trimethadione can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Coadministration of Cyclobenzaprine with Buprigesic 10mcg/Hr Transdermal Patch can increase the risk of developing side effects.

How to manage the interaction:
Coadministration of Buprigesic 10mcg/Hr Transdermal Patch with cyclobenzaprine can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor if you experience shortness of breath, chest discomfort, or palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also strengthen your muscles by lifting light weights.
  • Drink plenty of water during treatment with Buprigesic 10mcg/Hr Transdermal Patch to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Buprigesic 10mcg/Hr Transdermal Patch.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS
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Alcohol

Unsafe

Consuming alcohol or other illicit drugs during treatment with Buprigesic 10mcg/Hr Transdermal Patch increases your chances of experiencing these significant, life-threatening adverse effects. Throughout your therapy, do not consume alcohol, use alcohol-containing prescription or nonprescription medicines, or use street drugs.

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Pregnancy

Unsafe

If you are pregnant or planning pregnancy, inform your doctor. If you use Buprigesic 10mcg/Hr Transdermal Patch often throughout your pregnancy, your baby may suffer from potentially fatal withdrawal symptoms after birth. If your infant exhibits any of the following symptoms, contact your doctor straight away: irritability, hyperactivity, disturbed sleep, high-pitched scream, excessive shaking of a portion of the body, vomiting, diarrhoea, or failure to gain weight.

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Breast Feeding

Unsafe

If you are nursing, you should avoid using Buprigesic 10mcg/Hr Transdermal Patch. Buprenorphine passes into breast milk in small amounts and might cause respiratory issues in your infant. Talk with your doctor; they may prescribe a different pain reliever.

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Driving

Unsafe

Buprigesic 10mcg/Hr Transdermal Patch may cause dizziness, blurred vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after using Buprigesic 10mcg/Hr Transdermal Patch.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before using Buprigesic 10mcg/Hr Transdermal Patch.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before using Buprigesic 10mcg/Hr Transdermal Patch.

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Children

Unsafe

Buprigesic 10mcg/Hr Transdermal Patch is not recommended for children below 18 years of age as safety and effectiveness have not been established.

Have a query?

FAQs

Buprigesic 10mcg/Hr Transdermal Patch is used to treat Pain.

Buprigesic 10mcg/Hr Transdermal Patch consists of Buprenorphine is an opioid partial agonist. It provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

No, you are not recommended to take Buprigesic 10mcg/Hr Transdermal Patch with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Buprigesic 10mcg/Hr Transdermal Patch may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Buprigesic 10mcg/Hr Transdermal Patch with other medicines.

Yes, Buprigesic 10mcg/Hr Transdermal Patch may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while using Buprigesic 10mcg/Hr Transdermal Patch, do not stop using it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Yes, Buprigesic 10mcg/Hr Transdermal Patch may cause addiction, especially if taken for a prolonged time. Therefore, Buprigesic 10mcg/Hr Transdermal Patch should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Buprigesic 10mcg/Hr Transdermal Patch only as advised by a doctor, as overuse or misuse of Buprigesic 10mcg/Hr Transdermal Patch can lead to overdose or death.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - BUP0034

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