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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Buselin 0.5 mg Injection is indicated in women for the treatment of infertility and endometriosis. This medicine is also indicated in the treatment of prostate cancer (cancer of the prostate gland) in men who have not had testicles removed by surgery. It contains Buserelin, a synthetic version of the hormone that naturally occurs in the body. It works by stopping the production of natural hormones that control ovulation. It helps relieve symptoms of endometriosis by reducing the production of female sex hormones by acting on the pituitary gland. This medicine helps treat prostate cancer by reducing the production of testosterone and helps to stop the growth of cancer cells.

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Whats That

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Synonym :

BUSERELIN ACETATE

Composition :

BUSERELIN-0.5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Buselin 0.5 mg Injection

Buselin 0.5 mg Injection belongs to a group of medicines called gonadotropin-releasing hormone analogues indicated in women for the treatment of infertility and endometriosis. This medicine is also indicated in the treatment of prostate cancer (cancer of the prostate gland) in men who have not had testicles removed by surgery.

Buselin 0.5 mg Injection contains Buserelin, a synthetic version of the hormone that naturally occurs in the body. It works by stopping the production of natural hormones that control ovulation. It helps relieve symptoms of endometriosis by reducing the production of female sex hormones by acting on the pituitary gland. This medicine helps treat prostate cancer by reducing the production of testosterone and helps to stop the growth of cancer cells.

In some cases, Buselin 0.5 mg Injection may cause side effects like diarrhoea, constipation, nausea, vomiting, abdominal pain, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Avoid using Buselin 0.5 mg Injection if you are pregnant, think you are pregnant, breastfeeding, or have abnormal menstrual bleeding. Consult your doctor immediately if you become pregnant while on treatment with Buselin 0.5 mg Injection . Do not father a child during treatment with Buselin 0.5 mg Injection and for a few months afterwards, as it might harm the developing baby in the womb. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Buselin 0.5 mg Injection

Treatment of Infertility, Endometriosis, and Prostate cancer

Directions for Use

A healthcare professional will administer Buselin 0.5 mg Injection . After receiving proper training, you may be advised to inject the medicine yourself.

Medicinal Benefits

Buselin 0.5 mg Injection belongs to a group of medicines called gonadotropin-releasing hormone analogues indicated in the treatment of infertility and endometriosis in women. It is also indicated in the treatment of prostate cancer in men who have not had testicles removed by surgery. Buselin 0.5 mg Injection contains Buserelin, a synthetic version of the hormone that naturally occurs in the body. It acts on the pituitary gland in the brain to stop the production of natural hormones that control the release of eggs from the ovaries. Other hormonal treatments are then used to stimulate ovulation artificially. Female hormones such as oestrogen may worsen problems like endometriosis. It helps relieve symptoms of endometriosis by reducing the production of female sex hormones by acting on the pituitary gland. In men, it prevents the pituitary gland from releasing luteinising hormone. This prevents the testicles from producing testosterone, which is required by the prostate gland to grow. By reducing testosterone, it shrinks and prevents the growth of prostate cancer.

How Buselin 0.5 mg Injection Works

Buselin 0.5 mg Injection contains Buserelin, a synthetic version of the hormone that naturally occurs in the body. It works by stopping the production of natural hormones that control ovulation. It helps relieve symptoms of endometriosis by reducing the production of female sex hormones by acting on the pituitary gland. This medicine helps treat prostate cancer by reducing the production of testosterone and helps to stop the growth of cancer cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Buselin 0.5 mg Injection 0.5 ml
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Stay away from loud places because they can put more stress on hearing.
  • Wear hearing aids if a specialist has suggested it.
  • Unless instructed to do so by a doctor, do not use ototoxic substances, such as some over-the-counter medications.
  • Make an appointment with an audiologist for a hearing test
  • Get nutrients for ear health (e.g., magnesium, zinc).
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Buselin 0.5 mg Injection

As Buselin 0.5 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Buselin 0.5 mg Injection may cause weak, nervous, dizziness, headaches, hot flushes, stomach pain, swelling of the legs and breast pain, and pain, bleeding or hardening of the skin at the site of injection.

Drug Warnings

Do not use Buselin 0.5 mg Injection if you are allergic to any of its components, if you have abnormal menstrual bleeding, if you are pregnant or breastfeeding or if you have had an operation to remove testicles. Stop using Buselin 0.5 mg Injection and consult the doctor immediately if you become pregnant while on treatment with Buselin 0.5 mg Injection . Inform the doctor if you have depression, high blood pressure, diabetes, polycystic ovarian disease, heart/blood vessel conditions, heart rhythm problems, metabolic bone disease or risk factors for osteoporosis like smoking, chronic alcohol abuse, a family history of osteoporosis, or if you are on long-term treatment with corticosteroids or anticonvulsants. Stop using Buselin 0.5 mg Injection and consult a doctor immediately if you experience symptoms of serious side effect called ovarian hyperstimulation syndrome, such as diarrhoea, weight gain, difficulty breathing, shortness of breath, passing less urine, feeling sick or being sick, pain, swelling or a feeling of tension in your stomach. Ovarian hyperstimulation syndrome is more likely to occur if you are taking other hormones along with Buselin 0.5 mg Injection as a part of infertility treatment. Consult the doctor straight away if you notice bruising more easily than usual, signs of infections (fever, sore throat or mouth ulcers), severe headache, eyesight problems, or high blood pressure (crushing chest pain, problems with eyesight, confusion, tiredness and an uneven heartbeat).

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Include fibrous foods, iron-rich foods, foods rich in essential fatty acids, and anti-oxidant-rich foods in the diet.
  • Practice meditation and yoga. 
  • Avoid or limit caffeine intake.
  • Include healthy fruits and vegetables in your diet.
  • Avoid smoking and alcohol consumption.
  • Try relaxation therapy. Read a book or listen to soothing music.
  • Exercise moderately.
  • Do yoga or meditation, as it helps relieve stress.

Habit Forming

No

Therapeutic Class

HORMONES
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Alcohol

Consult your doctor

It is unknown if Buselin 0.5 mg Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Buselin 0.5 mg Injection is not recommended during pregnancy as it may be harmful to the developing baby. Please consult the doctor if you are pregnant, think you may be pregnant or become pregnant while on treatment with Buselin 0.5 mg Injection .

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Buselin 0.5 mg Injection as it might pass into the mother’s milk.

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Driving

Caution

Buselin 0.5 mg Injection may cause dizziness, drowsiness, or blurred eyesight. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Limited information is available. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Limited information is available. Please consult the doctor if you have a kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available. Please consult the doctor if you have any concerns.

Have a query?

FAQs

Buselin 0.5 mg Injection is used to treat Infertility, Endometriosis, and Prostate cancer.

Buselin 0.5 mg Injection works by stopping the production of natural hormones that control ovulation and relieves symptoms of endometriosis by reducing the production of female sex hormones. It reduces the production of testosterone, thereby preventing the growth of prostate cancer.

Buselin 0.5 mg Injection might cause menopausal symptoms such as hot flushes, dry vagina, increased sweating, loss of sex drive, or painful sexual intercourse in women. If these symptoms become serious or last longer than a few days, consult a doctor.

Buselin 0.5 mg Injection might increase the risk of osteoporosis if used for a longer duration due to a lowering in the amount of bone mineral. However, this effect is reversible when the treatment is stopped. Consult a doctor if you experience bone or muscle discomfort, such as shoulder stiffness or pain that lasts longer than a few days.

Buselin 0.5 mg Injection may increase the risk of heart rhythm problems. Inform the doctor if you have heart or blood vessel problems, including arrhythmia (heart rhythm problems), or if you are being treated with medicines for these conditions.

Buselin 0.5 mg Injection may cause muscle or bone pain, including pain in the back or jaw. Consult the doctor if you experience muscle or bone pain; the doctor may prescribe painkillers.

Buselin 0.5 mg Injection might affect blood sugar levels. You may need to check your blood glucose levels more regularly if you have diabetes.

You should call your doctor right away if you experience signs of allergic reactions such as rash, itching, hives, blisters and difficulty breathing. Also, inform your doctor if you experience chest pain, severe headache, fast/irregular heartbeat, severe dizziness, severe vomiting and vision changes.

A tumour flare reaction (TFR) is an immune response that can occur during cancer treatment, particularly with immunomodulatory drugs or immune checkpoint inhibitors. Yes, you may experience a tumour flare reaction (TFR) while on treatment with Buselin 0.5 mg Injection . During the first month of Buselin 0.5 mg Injection treatment, you might notice an increase in symptoms such as painful or difficult urination, blood in urine, weakness in your legs or sudden back or trunk pain. These are temporary and gradually reduce. However, if these symptoms persist, please contact your doctor immediately.

Yes, Buselin 0.5 mg Injection can cause weight gain in some patients. It’s important to maintain a balanced diet by eating fruits, vegetables, whole grains, and lean proteins. Avoid processed foods, sugary snacks, and high-calorie beverages. Engage in regular physical activity.

As a diabetic, it's important to take extra precautions while using Buselin 0.5 mg Injection as it may reduce the effect of drugs used to treat diabetes. Therefore, blood glucose levels should be checked regularly in diabetic patients. Be aware of symptoms like increased thirst, frequent urination, and unexplained weight changes, as these could indicate changes in your blood sugar levels. Consult your doctor if you have any concerns.

Yes, increased sweating is a common side effect of Buselin 0.5 mg Injection . This side effect usually occurs because Buselin 0.5 mg Injection affects hormone levels in your body and it usually stops a few months after treatment finishes. To manage this side effect, wear lightweight, breathable clothing and stay in cool, well-ventilated areas. Drink plenty of water to help regulate your body temperature and replace fluids lost through sweating.

Yes, loss of interest in sexual activity is a side effect of Buselin 0.5 mg Injection . Please consult your doctor if you experience this side effect.

Feeling exhausted is a common side effect of Buselin 0.5 mg Injection . Take some rest and stay hydrated by drinking plenty of water. Consult your doctor if this side effect persists.

The interaction of alcohol with Buselin 0.5 mg Injection is unknown. If you have any concerns, please discuss with your doctor.

Buselin 0.5 mg Injection may affect sperm quality and may harm a developing baby if pregnancy occurs. Therefore, you are recommended to use contraceptives while taking Buselin 0.5 mg Injection and consult your doctor for proper guidance if you have any concerns.

The common side effects of Buselin 0.5 mg Injection are diarrhoea, constipation, nausea, vomiting, abdominal pain, and headache. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - BUS0047

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Keep Refrigerated. Do not freeze.

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