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  3. Butrum 1mg Injection 1ml

Butrum 1mg Injection 1ml, Pack of 1 Injection
Butrum 1mg Injection 1ml, Pack of 1 Injection
Butrum 1mg Injection 1ml, Pack of 1 Injection
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Not for online sale
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Butrum 1mg Injection 1ml is used to treat moderate to severe pain. It contains Butorphanol which works by blocking the transmission of pain signals and changing the way body senses pain. In some cases, this medicine may cause side effects such as headache, dizziness, sleepiness, vomiting, nausea, and constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

BUTORPHANOL-1MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Butrum 1mg Injection 1ml

Butrum 1mg Injection 1ml belongs to the class of 'narcotic analgesics' primarily used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. Butrum 1mg Injection 1ml is also used as an anaesthesia adjunct during surgery and early labor. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. 

Butrum 1mg Injection 1ml contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Use this medicine as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Butrum 1mg Injection 1ml include headache, dizziness, sleepiness, vomiting, nausea, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor beforehand if you have liver, kidney, or heart diseases, breathing problems, mood disorders, brain-related problems, gastrointestinal disorders, underactive thyroid (hypothyroidism), drug addiction, and urination problems before starting Butrum 1mg Injection 1ml. It is essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Butrum 1mg Injection 1ml causes dizziness and drowsiness, so do not drive or operate machinery until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects. Butrum 1mg Injection 1ml is not recommended for people below 18 years of age.

Uses of Butrum 1mg Injection 1ml

Treatment of Pain relief.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Butrum 1mg Injection 1ml contains 'Butorphanol', an opioid analgesic that helps relieve moderate to severe pain post-surgery, muscle pain and migraine headaches. Butrum 1mg Injection 1ml is also used as a part of anaesthesia during surgery and early labor. It helps relieve pain in various conditions like toothache, rheumatoid arthritis, and osteoarthritis. It works by acting on the opioid receptors and blocking the transmission of pain signals.

How Butrum 1mg Injection 1ml Works

Butrum 1mg Injection 1ml contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Storage

Store in a cool and dry place away from sunlight
Side effects of Butrum 1mg Injection 1ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Butrum 1mg Injection 1ml

Since Butrum 1mg Injection 1ml is administered by a healthcare professional, an overdose is unlikely to occur. However, seek immediate medical attention if you experience symptoms of overdose such as a change in consciousness, extremely shallow or slow breathing, irregular heartbeats, loss of consciousness, shortness of breath, and swelling in hands and feet.

Drug Warnings

Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butrum 1mg Injection 1ml. If you have any mood disorders (toxic psychosis), spine problems (kyphoscoliosis), gastrointestinal problems (diarrhoea, paralytic ileus), personal or a family history of a substance use disorder like overuse of or addiction to drugs or alcohol, urination problems (enlarged prostate or urethral stricture) and an underactive thyroid (hypothyroidism), inform your doctor in advance before starting Butrum 1mg Injection 1ml. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Butrum 1mg Injection 1ml causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Butrum 1mg Injection 1ml is not recommended for anyone below 18 years of age.

Drug-Drug Interactions

verifiedApollotooltip
ButorphanolItraconazole
Severe
ButorphanolTramadol
Severe

Drug-Drug Interactions

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ButorphanolItraconazole
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Coadministration of Itraconazole with Butrum 1mg Injection 1ml may significantly raise Butrum 1mg Injection 1ml levels in the blood.

How to manage the interaction:
Despite the possibility of an interaction, Butrum 1mg Injection 1ml and itraconazole can be used if a doctor orders them. Consult a doctor if you feel dizziness, fainting, confusion, extreme sleepiness, a slow heartbeat, or breathing difficulties. Never stop taking any medications without talking to a doctor.
ButorphanolTramadol
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Co-administration of Butrum 1mg Injection 1ml with tramadol may increase the risk and severity of the seizure.

How to manage the interaction:
Taking Butrum 1mg Injection 1ml with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ButorphanolZiprasidone
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Coadministration of Butrum 1mg Injection 1ml with Ziprasidone can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Ziprasidone and Butrum 1mg Injection 1ml, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
ButorphanolCariprazine
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Taking Butrum 1mg Injection 1ml with Cariprazine can increase the risk of brain related problems.

How to manage the interaction:
Although there is a interaction between Cariprazine and Butrum 1mg Injection 1ml, but it can be taken if prescribed by a doctor. However, if you experience trouble breathing, feeling too sleepy or dizzy, having trouble focusing contact a doctor. Do not stop using any medications without a doctor's advice.
ButorphanolClonazepam
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Co-administration of Butrum 1mg Injection 1ml with Clonazepam can increase the risk of side effects.

How to manage the interaction:
Although taking Clonazepam and Butrum 1mg Injection 1ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ButorphanolVerapamil
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Taking verapamil with Butrum 1mg Injection 1ml may significantly increase the blood levels of Butrum 1mg Injection 1ml. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Butrum 1mg Injection 1ml together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impairment in thinking and judgment, fainting, confusion, excessive drowsiness, slow heart rate, and/or shallow or difficulty breathing. Avoid mentally demanding activities like operating dangerous machinery or driving, and exercise caution while rising from a sitting or lying posture. Do not stop taking any medication without consulting a doctor.
ButorphanolAprepitant
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Butrum 1mg Injection 1ml blood levels may rise if Aprepitant and Butrum 1mg Injection 1ml are used together.

How to manage the interaction:
Although taking Aprepitant with Butrum 1mg Injection 1ml could result in an interaction, it is safe to do so if advised by your doctor. Consult a doctor if you have sleepiness, dizziness, lightheadedness, difficulties concentrating, fainting, confusion, extreme drowsiness, slow heart rate, and/or shallow or difficult breathing. Do not discontinue any medications without talking to a doctor.
ButorphanolPosaconazole
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Posaconazole can raise the levels of Butrum 1mg Injection 1ml in the blood. The possibility of experiencing side effects of Butrum 1mg Injection 1ml may be increased.

How to manage the interaction:
Although using Posaconazole and Butrum 1mg Injection 1ml together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impaired thinking, or shortness of breath. Do not stop taking any medications without consulting a doctor.
ButorphanolEslicarbazepine
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Eslicarbazepine can lower the levels of Butrum 1mg Injection 1ml in the blood, resulting in decreased effectiveness of Butrum 1mg Injection 1ml in treating pain. Furthermore, if you have been receiving Butrum 1mg Injection 1ml as part of your treatment, adding eslicarbazepine could result in unpleasant withdrawal symptoms.

How to manage the interaction:
Although taking Eslicarbazepine and Butrum 1mg Injection 1ml can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience body aches, involuntary kicking and twitching, abdominal cramping, loss of appetite, nausea, vomiting, diarrhoea, watery eyes, runny nose, sneezing, yawning, excessive sweating, fever, chills, flushing, restlessness, irritability, anxiety, and depression consult your doctor immediately. You should avoid tasks requiring attentiveness, such as driving or using dangerous machinery. It is advised not to drink alcohol, self-medicate, or overdose on these drugs. Do not stop taking any medications without consulting your doctor.
ButorphanolFosphenytoin
Severe
How does the drug interact with Butrum 1mg Injection 1ml:
Combining Butrum 1mg Injection 1ml with Fosphenytoin can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Fosphenytoin with Butrum 1mg Injection 1ml can result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like watery eyes, runny nose, sneezing, yawning, sweating, fever, chills, restlessness, irritability, anxiety, depression, dilated pupils, trembling, fast heartbeat, twitching, loss of appetite, nausea, vomiting, diarrhoea, weight loss it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

Yes

Therapeutic Class

OPIOID ANALGESIC AND ANESTHESIA ADJUNCT

Butrum 1mg Injection 1ml Substitute

Substitutes safety advice

  • Butodol Injection 1 ml

    by Others

    ₹62.10per tablet

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Butrum 1mg Injection 1ml. Alcohol intake, along with Butrum 1mg Injection 1ml, may cause increased drowsiness and dizziness.

bannner image

Pregnancy

Caution

Please consult your doctor before taking Butrum 1mg Injection 1ml if you are pregnant or planning to conceive.

bannner image

Breast Feeding

Caution

Butrum 1mg Injection 1ml is excreted into the breast milk. Please consult your doctor before taking Butrum 1mg Injection 1ml if you are a nursing mother.

bannner image

Driving

Unsafe

Butrum 1mg Injection 1ml may make you feel dizzy and drowsy. Do not drive or operate machinery if you experience these side effects.

bannner image

Liver

Caution

Please consult your doctor since Butrum 1mg Injection 1ml should be used with caution in patients with liver impairment/liver disease.

bannner image

Kidney

Caution

Please consult your doctor since Butrum 1mg Injection 1ml should be used with caution in patients with kidney impairment/kidney disease.

bannner image

Children

Unsafe

Butrum 1mg Injection 1ml is not recommended in anyone below 18 years of age.

FAQs

Butrum 1mg Injection 1ml is used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. It is also used as an anaesthesia adjunct during surgery and early labour.

Butrum 1mg Injection 1ml contains 'Butorphanol', an opioid pain reliever that blocks the transmission of pain signals by acting on specific centres of the brain. Thus Butrum 1mg Injection 1ml reduces pain associated with various conditions like surgery pain, muscle pain, migraine headaches, arthritis pain and toothache.

Butrum 1mg Injection 1ml may cause your blood pressure to drop upon administration of nasal spray. This may lead to fainting, light-headedness and dizziness after its use in the first hour. To prevent this from happening, remain sitting or lying down after using Butrum 1mg Injection 1ml.

It is not recommended to suddenly stop taking Butrum 1mg Injection 1ml since it may produce withdrawal symptoms, especially when you used Butrum 1mg Injection 1ml for a longer time or in high doses. Please seek medical advice on how to stop taking Butrum 1mg Injection 1ml safely. Your doctor may lower your dose slowly to prevent withdrawal symptoms.

Butrum 1mg Injection 1ml can cause side effects like dizziness and drowsiness, hence it is advised to remain sitting or lying after taking Butrum 1mg Injection 1ml. You are also advised not to drive or operate machinery until you are mentally alert.

Butrum 1mg Injection 1ml may sometimes cause addiction despite its medical benefits. The risk of habit-forming or addiction is higher in people with a history of substance use disorder like overuse of drugs and alcohol. It is strictly recommended to use Butrum 1mg Injection 1ml in the dose and duration prescribed by your doctor. Do not double the dose.

If you have liver or kidney issues, you should use Butrum 1mg Injection 1ml with caution as it is primarily excreted through the kidneys, and its use may pose a higher risk of side effects in patients with impaired kidney function. Butrum 1mg Injection 1ml is also extensively metabolized in the liver. Always consult your doctor before using Butrum 1mg Injection 1ml if you have liver or kidney problems.

If you suddenly stop using Butrum 1mg Injection 1ml, you may experience withdrawal symptoms such as nausea, vomiting, fatigue, dizziness, drowsiness, irritability, insomnia or runny nose. It is important to consult your doctor before discontinuing Butrum 1mg Injection 1ml, as they can provide guidance on safely minimizing withdrawal effects.

While on therapy with Butrum 1mg Injection 1ml, be cautious if you experience drowsiness and dizziness, or if you have breathing problems, and avoid driving or operating heavy machinery. Be aware of the potential for dependence or withdrawal symptoms with prolonged use of Butrum 1mg Injection 1ml. Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butrum 1mg Injection 1ml.

Butrum 1mg Injection 1ml causes side effects such as constipation, nausea, vomiting, dizziness, drowsiness, and headache. These do not require any medical attention as they will gradually reduce over time. Please, contact a doctor if these persist longer

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - BUT0004

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.webmd.com/drugs/2/drug-5001/butorphanol-nasal/details
  2. https://www.drugs.com/mtm/butorphanol-injection.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/19890s17lbl.pdf
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