What is the use of Butrum 2 mg Injection?

Butrum 2 mg Injection is used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. It is also used as an anaesthesia adjunct during surgery and early labour.

How does Butrum 2 mg Injection work?

Butrum 2 mg Injection contains 'Butorphanol', an opioid pain reliever that blocks the transmission of pain signals by acting on specific centres of the brain. Thus Butrum 2 mg Injection reduces pain associated with various conditions like surgery pain, muscle pain, migraine headaches, arthritis pain and toothache.

Does Butrum 2 mg Injection affect blood pressure?

Butrum 2 mg Injection may cause your blood pressure to drop upon administration of nasal spray. This may lead to fainting, light-headedness and dizziness after its use in the first hour. To prevent this from happening, remain sitting or lying down after using Butrum 2 mg Injection.

Can I stop taking Butrum 2 mg Injection once I feel better?

It is not recommended to suddenly stop taking Butrum 2 mg Injection since it may produce withdrawal symptoms, especially when you used Butrum 2 mg Injection for a longer time or in high doses. Please seek medical advice on how to stop taking Butrum 2 mg Injection safely. Your doctor may lower your dose slowly to prevent withdrawal symptoms.

Does Butrum 2 mg Injection cause dizziness?

Butrum 2 mg Injection can cause side effects like dizziness and drowsiness, hence it is advised to remain sitting or lying after taking Butrum 2 mg Injection. You are also advised not to drive or operate machinery until you are mentally alert.

Does Butrum 2 mg Injection cause addiction?

Butrum 2 mg Injection may sometimes cause addiction despite its medical benefits. The risk of habit-forming or addiction is higher in people with a history of substance use disorder like overuse of drugs and alcohol. It is strictly recommended to use Butrum 2 mg Injection in the dose and duration prescribed by your doctor. Do not double the dose.

Can I take Butrum 2 mg Injection if I have liver or kidney issues?

If you have liver or kidney issues, you should use Butrum 2 mg Injection with caution as it is primarily excreted through the kidneys, and its use may pose a higher risk of side effects in patients with impaired kidney function. Butrum 2 mg Injection is also extensively metabolized in the liver. Always consult your doctor before using Butrum 2 mg Injection if you have liver or kidney problems.

What withdrawal symptoms might I experience if I stop Butrum 2 mg Injection suddenly?

If you suddenly stop using Butrum 2 mg Injection, you may experience withdrawal symptoms such as nausea, vomiting, fatigue, dizziness, drowsiness, irritability, insomnia or runny nose. It is important to consult your doctor before discontinuing Butrum 2 mg Injection, as they can provide guidance on safely minimizing withdrawal effects.

What are the side effects of Butrum 2 mg Injection?

Butrum 2 mg Injection causes side effects such as constipation, nausea, vomiting, dizziness, drowsiness, and headache. These do not require any medical attention as they will gradually reduce over time. Please, contact a doctor if these persist longer

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Butrum 2 mg Injection is used to treat moderate to severe pain. It contains Butorphanol which works by blocking the transmission of pain signals and changing the way body senses pain. In some cases, this medicine may cause side effects such as headache, dizziness, sleepiness, vomiting, nausea, and constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Butrum 2 mg Injection

Butrum 2 mg Injection belongs to the class of 'narcotic analgesics' primarily used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. Butrum 2 mg Injection is also used as an anaesthesia adjunct during surgery and early labor. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body.

Butrum 2 mg Injection contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Use this medicine as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Butrum 2 mg Injection include headache, dizziness, sleepiness, vomiting, nausea, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor beforehand if you have liver, kidney, or heart diseases, breathing problems, mood disorders, brain-related problems, gastrointestinal disorders, underactive thyroid (hypothyroidism), drug addiction, and urination problems before starting Butrum 2 mg Injection. It is essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Butrum 2 mg Injection causes dizziness and drowsiness, so do not drive or operate machinery until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects. Butrum 2 mg Injection is not recommended for people below 18 years of age.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Butrum 2 mg Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Butrum 2 mg Injection contains 'Butorphanol', an opioid analgesic that helps relieve moderate to severe pain post-surgery, muscle pain and migraine headaches. Butrum 2 mg Injection is also used as a part of anaesthesia during surgery and early labor. It helps relieve pain in various conditions like toothache, rheumatoid arthritis, and osteoarthritis. It works by acting on the opioid receptors and blocking the transmission of pain signals.

How Butrum 2 mg Injection Works

Butrum 2 mg Injection contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Storage

Store in a cool and dry place away from sunlight

Side effects of Butrum 2 mg Injection

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Blocked Nose

A blocked nose can be relieved by drinking more water, which helps clear fluids.
Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
Keep a humidifier around to moisten air at home/workplace.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Butrum 2 mg Injection

Since Butrum 2 mg Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek immediate medical attention if you experience symptoms of overdose such as a change in consciousness, extremely shallow or slow breathing, irregular heartbeats, loss of consciousness, shortness of breath, and swelling in hands and feet.

Drug Warnings

Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butrum 2 mg Injection. If you have any mood disorders (toxic psychosis), spine problems (kyphoscoliosis), gastrointestinal problems (diarrhoea, paralytic ileus), personal or a family history of a substance use disorder like overuse of or addiction to drugs or alcohol, urination problems (enlarged prostate or urethral stricture) and an underactive thyroid (hypothyroidism), inform your doctor in advance before starting Butrum 2 mg Injection. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Butrum 2 mg Injection causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Butrum 2 mg Injection is not recommended for anyone below 18 years of age.

Drug-Drug Interactions

ButorphanolClotrimazole

Severe

ButorphanolKetoconazole

Severe

Drug-Drug Interactions

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ButorphanolClotrimazole

Severe

How does the drug interact with Butrum 2 mg Injection:
Coadministration of Butrum 2 mg Injection with clotrimazole may increase the blood levels of Butrum 2 mg Injection. This may increase side effects such as sleepiness, feeling dizzy and lightheadedness, difficulty concentrating, and impairment in thinking and judgement.

How to manage the interaction:
Although taking Clotrimazole with Butrum 2 mg Injection may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience dizziness, confusion, drowsiness, or difficulty breathing. Avoid tasks that require mental awareness, such as driving, and use care when rising from a sitting or laying position. Do not discontinue any medication without consulting your doctor.

ButorphanolKetoconazole

Severe

How does the drug interact with Butrum 2 mg Injection:
Coadministration of Ketoconazole and Butrum 2 mg Injection may increase the blood levels of Butrum 2 mg Injection. This may increase side effects (drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment).

How to manage the interaction:
Although taking Ketoconazole and Butrum 2 mg Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop dizziness, fainting, confusion, excessive sleepiness, a slow heartbeat, shallow breathing, you should consult a doctor. Do not discontinue any medication without consulting a doctor.

ButorphanolClonazepam

Severe

How does the drug interact with Butrum 2 mg Injection:
Co-administration of Butrum 2 mg Injection with Clonazepam can increase the risk of side effects.

How to manage the interaction:
Although taking Clonazepam and Butrum 2 mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

ButorphanolModafinil

Severe

How does the drug interact with Butrum 2 mg Injection:
Combining Butrum 2 mg Injection with Modafinil may significantly reduce the blood levels of Butrum 2 mg Injection. This may lead to poor treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Modafinil and Butrum 2 mg Injection, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like pain, watery eyes, runny nose, sweating, fever, chills, restlessness, irritability, anxiety, fast heartbeat, twitching, loss of appetite, nausea, vomiting, diarrhea, or weight loss it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.

ButorphanolFentanyl

Severe

How does the drug interact with Butrum 2 mg Injection:
Taking fentanyl and Butrum 2 mg Injection together can increase the risk of side effects.

How to manage the interaction:
Although taking Fentanyl together with Butrum 2 mg Injection can result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.

ButorphanolZiprasidone

Severe

How does the drug interact with Butrum 2 mg Injection:
Coadministration of Butrum 2 mg Injection with Ziprasidone can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Ziprasidone and Butrum 2 mg Injection, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.

ButorphanolBaclofen

Severe

How does the drug interact with Butrum 2 mg Injection:
Co-administration of Baclofen with Butrum 2 mg Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Baclofen and Butrum 2 mg Injection, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

ButorphanolHydroxyzine

Severe

How does the drug interact with Butrum 2 mg Injection:
Using Hydroxyzine together with Butrum 2 mg Injection can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Hydroxyzine and Butrum 2 mg Injection, but it can be taken if prescribed by a doctor. Since these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgment, response speed, and motor coordination, you should avoid driving or operating dangerous machinery until you know how they affect you. Do not discontinue any medications without consulting a doctor.

ButorphanolVoriconazole

Severe

How does the drug interact with Butrum 2 mg Injection:
Taking Butrum 2 mg Injection with Voriconazole may significantly increase the blood levels of Butrum 2 mg Injection which increases risk of side effects.

How to manage the interaction:
Although taking Butrum 2 mg Injection and Voriconazole together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience dizziness, or difficulty concentrating consult a doctor. Do not stop using any medications without consulting a doctor.

ButorphanolChlordiazepoxide

Severe

How does the drug interact with Butrum 2 mg Injection:
Co-administration of Butrum 2 mg Injection with chlordiazepoxide can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Butrum 2 mg Injection and chlordiazepoxide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, shortness of breath, palpitations, numbness in hands and feet, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
Performing yoga may also help in improving joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
Avoid smoking and alcohol consumption.

Habit Forming

Yes

Therapeutic Class

OPIOID ANALGESIC AND ANESTHESIA ADJUNCT

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Butrum 2 mg Injection. Alcohol intake, along with Butrum 2 mg Injection, may cause increased drowsiness and dizziness.