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  3. Cabozanib 60 Tablet 30's

Cabozanib 60 Tablet 30's, Pack of 1 CAPSULE
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cabozanib 60 Tablet is used to treat renal cell carcinoma. It contains Cabozantinib as an active ingredient, which works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding. Cabozanib 60 Tablet may cause side effects such as diarrhoea, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, reduced weight, dizziness, and constipation.

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Composition :

CABOZANTINIB-60MG

Manufacturer/Marketer :

BDR Pharmaceuticals Internationals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cabozanib 60 Tablet

Cabozanib 60 Tablet is an anti-cancer medicine used in the treatment of renal cell carcinoma. It is a disease in which cancer cells grow uncontrollably in the kidney and form a tumor. Cabozanib 60 Tablet is used in treating advanced renal cell carcinoma as first-line therapy for advanced renal cell carcinoma in combination with nivolumab and hepatocellular carcinoma in patients who have previously been treated with sorafenib.

Cabozanib 60 Tablet contains Cabozantinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Cabozanib 60 Tablet may cause certain side effects such as diarrhea, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, decreased weight, dizziness, and constipation. Inform your doctor if any of these side effects bother you. Cabozanib 60 Tablet should be taken as advised by your doctor.

Avoid taking Cabozanib 60 Tablet if you are allergic to it or any other components of it. Before taking Cabozanib 60 Tablet , inform your doctor if you have/had liver or kidney disease, gastrointestinal disorders, heart problems, blood or bleeding disorders, open or healing wounds, and a history of recent surgery. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

Uses of Cabozanib 60 Tablet

Cabozanib 60 Tablet is used in the treatment of Renal Cell Carcinoma and Hepatocellular carcinoma. The detailed uses of Cabozanib 60 Tablet are as follows:<br/>• Renal Cell Carcinoma (RCC): Cabozanib 60 Tablet is used for treating advanced kidney cancer.<br/>• Hepatocellular Carcinoma (HCC): Cabozanib 60 Tablet is used for liver cancer in patients previously treated with sorafenib.<br/>• Medullary Thyroid Cancer (MTC): Cabozanib 60 Tablet is especially used when the cancer is progressive and metastatic.<br/>

Directions for Use

• Cabozanib 60 Tablet should be taken on an empty stomach at least one hour before food and 2 hours after food, or as advised by your doctor.• It is recommended to take Cabozanib 60 Tablet once daily or as advised by your doctor.• Swallow the whole tablet with a glass of water.• Do not break, chew or crush Cabozanib 60 Tablet .

Medicinal Benefits

Cabozanib 60 Tablet contains Cabozantinib, which is used in treating advanced renal cell carcinoma and liver cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Cabozanib 60 Tablet stops the body's production, spread and growth of cancerous cells.

How Cabozanib 60 Tablet Works

Cabozanib 60 Tablet contains Cabozantinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cabozanib 60 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cabozanib 60 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Maintain your magnesium levels and general health by drinking lots of water.
  • Maintain a diet high in magnesium-rich foods such as spinach, almonds, chickpeas and brown rice.
  • Limit your alcohol intake because too much of it lowers your magnesium levels.
  • Plan blood testing on a regular basis to monitor magnesium levels.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Cabozanib 60 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Cabozanib 60 Tablet may include memory loss, confusion, and weight loss. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort.

Drug Warnings

To treat your condition effectually, continue taking Cabozanib 60 Tablet for the period that your doctor has prescribed. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, blood or bleeding disorders, open/healing of wound, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Cabozanib 60 Tablet may cause hypertension, thrombotic events, hemorrhagic events, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), hepatotoxicity, severe diarrhoea, Osteonecrosis of the jaw (ONJ), Palmar-Plantar Erythrodysesthesia (PPE), adrenal insufficiency, impaired wound healing, and proteinuria in some patients. Hence, inform your doctor about your complete medication and medical history before taking Cabozanib 60 Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause dizziness. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

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CabozantinibDoxepin
Severe
CabozantinibPrimaquine
Severe

Drug-Drug Interactions

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CabozantinibDoxepin
Severe
How does the drug interact with Cabozanib 60 Tablet:
Coadministration of Cabozanib 60 Tablet with Doxepin can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Cabozanib 60 Tablet with Doxepin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
CabozantinibPrimaquine
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking primaquine and Cabozanib 60 Tablet together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Primaquine and Cabozanib 60 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
CabozantinibGoserelin
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking Goserelin and Cabozanib 60 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Goserelin and Cabozanib 60 Tablet together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CabozantinibClopidogrel
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking Cabozanib 60 Tablet together with clopidogrel may increase the risk of bleeding.

How to manage the interaction:
Taking Clopidogrel with Cabozanib 60 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor immediately if you notice symptoms like bleeding, bruising, dizziness, or black stools. Do not stop using any medications without a doctor's advice.
CabozantinibDabigatran etexilate
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking Dabigatran etexilate with Cabozanib 60 Tablet can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Cabozanib 60 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
CabozantinibVoriconazole
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking Cabozanib 60 Tablet with Voriconazole may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Cabozanib 60 Tablet and Voriconazole together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience dizziness, shortness of breath, heart palpitations (irregular heartbeat), fever, and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting a doctor.
CabozantinibAzithromycin
Severe
How does the drug interact with Cabozanib 60 Tablet:
Taking azithromycin with cabozantinb may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using azithromycin alongside cabozantinb can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CabozantinibDiclofenac Diethylamine
Severe
How does the drug interact with Cabozanib 60 Tablet:
Co-administration of Cabozanib 60 Tablet and Diclofenac Diethylamine can increase the risk of severe unusual bleeding.

How to manage the interaction:
Co-administration of Cabozanib 60 Tablet and Diclofenac Diethylamine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting blood, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
CabozantinibAlprazolam
Severe
How does the drug interact with Cabozanib 60 Tablet:
Concomitant use of Alfuzosin with Cabozanib 60 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alfuzosin with Cabozanib 60 Tablet can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
CabozantinibSolifenacin
Severe
How does the drug interact with Cabozanib 60 Tablet:
Coadministration of Solifenacin with Cabozanib 60 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Solifenacin and Cabozanib 60 Tablet, but it can be taken if prescribed by a doctor. If you experience drowsiness, dizziness, irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Cabozanib 60 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol while on treatment with Cabozanib 60 Tablet as it may cause serious side effects.

bannner image

Pregnancy

Unsafe

Cabozanib 60 Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Cabozanib 60 Tablet . You should not become pregnant while you are taking Cabozanib 60 Tablet for at least four months from the last dose of Cabozanib 60 Tablet . Using effective birth control methods while on treatment is suggested.

bannner image

Breast Feeding

Unsafe

Cabozanib 60 Tablet should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and for at least four months from the last dose of medicine.

bannner image

Driving

Unsafe

In some cases, Cabozanib 60 Tablet may cause dizziness and visual problems. As a result, do not drive, operate machinery, or engage in any activity that requires clear vision until you are satisfied you can drive while on Cabozanib 60 Tablet therapy.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Cabozanib 60 Tablet is known to cause hepatotoxicity when taken in combination with nivolumab. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Cabozanib 60 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Cabozanib 60 Tablet is not recommended for use in children as the safety and efficacy are not established.

Have a query?

FAQs

Cabozanib 60 Tablet is used to treat Renal Cell Carcinoma and Hepatocellular carcinoma.

Cabozanib 60 Tablet contains Cabozantinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

Cabozanib 60 Tablet may cause thyroid dysfunction, leading to decreased thyroid hormone levels. This effect causes hypothyroidism. So, notify your doctor if you feel extremely tired, colder than others, sudden weight gain/ weight loss, hair loss, or change in voice while using this medicine.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - CAB0089

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/208692s010lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a616037.html
  3. https://reference.medscape.com/drug/cometriq-cabometyx-cabozantinib-999791
  4. https://www.cabometyx.com/
  5. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/cabozantinib

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