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Composition :

ELTROMBOPAG-50MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cadeltro 50mg Tablet 14's

Cadeltro 50mg Tablet 14's is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Cadeltro 50mg Tablet 14's is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Cadeltro 50mg Tablet 14's contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone, stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Cadeltro 50mg Tablet 14's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Cadeltro 50mg Tablet 14's helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

In some cases, Cadeltro 50mg Tablet 14's can cause common side effects like nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Cadeltro 50mg Tablet 14's or any other medicines before starting Cadeltro 50mg Tablet 14's. Consult the doctor if you are pregnant or planning to conceive. Cadeltro 50mg Tablet 14's is not indicated for use in breastfeeding since it passes into the breast milk.

Uses of Cadeltro 50mg Tablet 14's

Cadeltro 50mg Tablet 14's is used in the treatment of low platelet count (thrombocytopenia) in various blood-related disorders. The detailed uses of Cadeltro 50mg Tablet 14's are as follows:

  • Treats Chronic Immune Thrombocytopenia (ITP): Cadeltro 50mg Tablet 14's is used to treat chronic ITP in patients who have not responded adequately to treatments such as immunoglobulins, corticosteroids, and splenectomy (surgical removal of spleen).
  • Manages Thrombocytopenia in Hepatitis C Virus (HCV) infection: Cadeltro 50mg Tablet 14's helps increase platelet counts in chronic HCV patients, making it safer for them to start and continue treatment with interferon.
  • Treats Severe Aplastic Anaemia (SAA): Cadeltro 50mg Tablet 14's is used for patients with SAA who have not responded to immunosuppressive treatment, helping to stimulate bone marrow to produce more blood cells.
  • Prevents Bleeding Episodes: By increasing platelet count, Cadeltro 50mg Tablet 14's reduces the risk of bleeding associated with low platelet levels in various blood disorders.

Have a query?

Directions for Use

  • Cadeltro 50mg Tablet 14's can be taken on an empty stomach, at least 1 hour before or 2 hours after eating.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Cadeltro 50mg Tablet 14's as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Cadeltro 50mg Tablet 14's contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults.
  • Cadeltro 50mg Tablet 14's works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets.
  • The increase in these bone marrow cells stimulates the production of platelets. Thus Cadeltro 50mg Tablet 14's prevents bleeding episodes by increasing the number of platelets in the blood.

How Cadeltro 50mg Tablet 14's Works

Cadeltro 50mg Tablet 14's contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Cadeltro 50mg Tablet 14's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Cadeltro 50mg Tablet 14's helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cadeltro 50mg Tab
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Cadeltro 50mg Tablet 14's

Take Cadeltro 50mg Tablet 14's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include rash, slowed heartbeat, and excessive tiredness. It may also cause life-threatening blood clots. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Cadeltro 50mg Tablet 14's or other medicines, please inform your doctor in advance.
  • Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Cadeltro 50mg Tablet 14's.
  • Take Cadeltro 50mg Tablet 14's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Cadeltro 50mg Tablet 14's.
  • Cadeltro 50mg Tablet 14's is not recommended during pregnancy since it may have harmful effects on the foetus.
  • Consult your doctor before using Cadeltro 50mg Tablet 14's if you are a breastfeeding mother.
  • Do not drive or operate machinery since Cadeltro 50mg Tablet 14's may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive.
  • Avoid or limit alcohol consumption with Cadeltro 50mg Tablet 14's as it may affect the efficacy of Cadeltro 50mg Tablet 14's.
  • Cadeltro 50mg Tablet 14's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Drug-Drug Interactions

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EltrombopagFerric maltol
Critical
EltrombopagAluminium hydroxide
Critical

Drug-Drug Interactions

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EltrombopagFerric maltol
Critical
How does the drug interact with Cadeltro 50mg Tab:
Ferric maltol can make Cadeltro 50mg Tab less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Cadeltro 50mg Tab is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Cadeltro 50mg Tab on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Cadeltro 50mg Tab:
Coadministration of Cadeltro 50mg Tab and aluminum hydroxide may interfere with the absorption of Cadeltro 50mg Tab and reduce its effectiveness.

How to manage the interaction:
Taking Cadeltro 50mg Tab with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cadeltro 50mg Tab:
When Cadeltro 50mg Tab is mixed with Calcium chloride, the amount of Cadeltro 50mg Tab in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Cadeltro 50mg Tab with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Cadeltro 50mg Tab:
Taking magnesium citrate with Cadeltro 50mg Tab can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Cadeltro 50mg Tab is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Cadeltro 50mg Tab on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cadeltro 50mg Tab:
Coadministration of Magnesium oxide with Cadeltro 50mg Tab can impair the absorption of Cadeltro 50mg Tab which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Cadeltro 50mg Tab together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Cadeltro 50mg Tab:
Ferrous gluconate can make Cadeltro 50mg Tab less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Cadeltro 50mg Tab with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Cadeltro 50mg Tab on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cadeltro 50mg Tab:
Co-administration of Cadeltro 50mg Tab and Calcium gluconate may interfere with the absorption of Cadeltro 50mg Tab and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Cadeltro 50mg Tab if prescribed by the doctor. However, take Cadeltro 50mg Tab on an empty stomach, i.e., 2 hours before or 4 hours after taking calcium gluconate. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cadeltro 50mg Tab:
When Pazopanib and Cadeltro 50mg Tab are taken together, the body's ability to break down Pazopanib may be reduced. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Cadeltro 50mg Tab with Pazopanib together can result in an interaction, but it can be taken if your doctor has advised it. If you are having any of these symptoms like irregular heart rhythm, bleeding, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, bleeding, sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain, pain in your arms, back, neck, shortness of breath, numbness, weakness on one side of your body, slurred speech or difficulty speaking, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagLomitapide
Severe
How does the drug interact with Cadeltro 50mg Tab:
Coadministration of Cadeltro 50mg Tab and Lomitapide can increase the risk or severity of liver disease.

How to manage the interaction:
There may be a possibility of interaction between Cadeltro 50mg Tab and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, bleeding, nausea, vomiting, abdominal pain, dark urine, or liver damage. Do not discontinue any medications without consulting a doctor.
EltrombopagMipomersen
Severe
How does the drug interact with Cadeltro 50mg Tab:
Coadministration of Cadeltro 50mg Tab with Mipomersen can increase the risk or severity of liver injury.

How to manage the interaction:
Co-administration of Cadeltro 50mg Tab with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, bleeding, nausea, vomiting, abdominal pain, or dark urine it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • A high-protein diet, such as lean meat, chicken, crab, turkey, beef and fish, can help increase platelet count.
  • Eating Papayaa is the best natural remedy to increase your platelet count, and you can also use Papayaa leaves mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

PLATELET STIMULATING AGENTS
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Alcohol

Caution

Limit alcohol intake, along with Cadeltro 50mg Tablet 14's, to attain the maximum efficacy of Cadeltro 50mg Tablet 14's and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Cadeltro 50mg Tablet 14's is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Cadeltro 50mg Tablet 14's is excreted into the breast milk. Please consult your doctor for more information before taking Cadeltro 50mg Tablet 14's if you are a nursing mother.

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Driving

Caution

Cadeltro 50mg Tablet 14's may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Cadeltro 50mg Tablet 14's. Cadeltro 50mg Tablet 14's may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Cadeltro 50mg Tablet 14's.

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Kidney

Consult your doctor

Cadeltro 50mg Tablet 14's should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Cadeltro 50mg Tablet 14's if you have any kidney problems.

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Children

Caution

Cadeltro 50mg Tablet 14's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

FAQs

Cadeltro 50mg Tablet 14's is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also used to treat severe aplastic anemia (SAA) in adults.

Cadeltro 50mg Tablet 14's contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Cadeltro 50mg Tablet 14's lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).

Do not stop using Cadeltro 50mg Tablet 14's even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

Cadeltro 50mg Tablet 14's should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.

Cadeltro 50mg Tablet 14's decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.

It is advised to take Cadeltro 50mg Tablet 14's on an empty stomach. Please take Cadeltro 50mg Tablet 14's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Cadeltro 50mg Tablet 14's.

Cadeltro 50mg Tablet 14's should be swallowed whole. Do not chew or crush the tablets.

It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take Cadeltro 50mg Tablet 14's at around the same time every day.

It may take up to 2 weeks for patients to respond to Cadeltro 50mg Tablet 14's.

Cadeltro 50mg Tablet 14's should not be taken with foods, beverages, or other medicines that contain high concentrations of aluminium, calcium, iron, magnesium, selenium and zinc.

Cadeltro 50mg Tablet 14's should be stored in a cool and dry place away from sunlight. Keep out of sight and reach of children.

Cadeltro 50mg Tablet 14's can cause or increase the risk of severe liver issues. Check with your doctor straight away if you or your child experience nausea or vomiting, dark urine, light-coloured stools, right upper stomach pain, unusual exhaustion, or yellow eyes or skin while taking this medication.

Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Country of origin

INDIA

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - CAD0476

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