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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cafirate 20mg Injection 1ml is used to treat apnea in premature newborns/neonates. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow. Common side effects include a fast heartbeat, irregular heartbeat, and hyperglycemia. It is a pediatric medication. Inform your doctor if your newborn is allergic to Cafirate 20mg Injection 1ml.
 

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Whats That

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Synonym :

CAFFEINE

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cafirate 20mg Injection 1ml

Cafirate 20mg Injection 1ml belongs to a group of medicines known as methylxanthines. It is used to treat apnea of premature newborns. Apnea is a condition in which breathing is interrupted, causing abnormal heart rate and oxygen saturation changes. It is a common occurrence, particularly in premature infants.

Cafirate 20mg Injection 1ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Cafirate 20mg Injection 1ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

A paediatrician or healthcare professional will administer Cafirate 20mg Injection 1ml in a hospital setting. Cafirate 20mg Injection 1ml can cause side effects like a fast heartbeat, irregular heartbeat, and increased blood sugar levels. These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant and are being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before adjusting the dose, your doctor may assess your child's baseline serum caffeine levels if they were born to a mother who consumes caffeine.

Uses of Cafirate 20mg Injection 1ml

Cafirate 20mg Injection 1ml is commonly used to
1. Treat prematurity apnea:
Caffeine citrate is most commonly used to treat premature infants, particularly those born preterm. Premature babies, particularly those born before 28 weeks of gestation, may experience pauses in breathing lasting more than 20 seconds (apnea). This is known as apnea of prematurity, and caffeine citrate is used to stimulate the respiratory centre in the brain, hence improving breathing and decreasing apnea episodes.
2. Respiratory stimulation:
Cafirate 20mg Injection 1ml works as a central respiratory stimulant, which means it can be beneficial in instances when respiratory function is limited, particularly in preterm infants with underdeveloped respiratory systems.
3. Improvement of Diuresis:
Caffeine is a moderate diuretic, but this is not the primary reason for its usage in therapeutic settings.
4. Treatment for Neonatal Respiratory Depression:
Caffeine citrate may be utilised in newborns with respiratory depression, particularly when it is associated with disorders such as hypoxia or birth asphyxia.

Directions for Use

Cafirate 20mg Injection 1ml will be administered by a healthcare professional. Hence, do not self-administer to your newborn.

Medicinal Benefits

Cafirate 20mg Injection 1ml contains Caffeine Citrate as an active ingredient, which belongs to the central nervous system (CNS) stimulants class. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow.

How Cafirate 20mg Injection 1ml Works

Cafirate 20mg Injection 1ml contains Caffeine Citrate, which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Cafirate 20mg Injection 1ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Cafirate 20mg Injection 1ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include anxiety, stomach pain, irregular/fast heartbeat, seizures, and trouble sleeping. If your newborn experiences these symptoms or if you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. Cafirate 20mg Injection 1ml should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Caution

Cafirate 20mg Injection 1ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

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Driving

Not applicable

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Liver

Caution

Cafirate 20mg Injection 1ml should be used with caution in infants with impaired liver function.

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Kidney

Caution

Cafirate 20mg Injection 1ml should be used with caution in infants with impaired kidney function.

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Children

Consult your doctor

Cafirate 20mg Injection 1ml is intended for use in premature newborns and neonates. Consult your doctor for more information.

Have a query?

FAQs

Cafirate 20mg Injection 1ml is used in the treatment of apnea of premature newborns.

Cafirate 20mg Injection 1ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory center, sensitizing it to hypercapnia. Thereby Cafirate 20mg Injection 1ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

No, it is intended to treat apnea in premature newborns and neonates.

The dosage is determined by your babys weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - CAF0034

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