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  3. Cafneon 40 mg Injection 2 ml

Cafneon 40 mg Injection 2 ml, Pack of 1
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cafneon 40 mg Injection 2 ml is used to treat apnea in premature newborns/neonates. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow. Common side effects include a fast heartbeat, irregular heartbeat, and hyperglycemia. It is a pediatric medication. Inform your doctor if your newborn is allergic to Cafneon 40 mg Injection 2 ml.
 

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Synonym :

CAFFEINE

Composition :

CAFFEINE CITRATE-40MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cafneon 40 mg Injection 2 ml

Cafneon 40 mg Injection 2 ml belongs to a group of medicines known as methylxanthines. It is used to treat apnea of premature newborns. Apnea is a condition in which breathing is interrupted, causing abnormal heart rate and oxygen saturation changes. It is a common occurrence, particularly in premature infants.

Cafneon 40 mg Injection 2 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Cafneon 40 mg Injection 2 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

A paediatrician or healthcare professional will administer Cafneon 40 mg Injection 2 ml in a hospital setting. Cafneon 40 mg Injection 2 ml can cause side effects like a fast heartbeat, irregular heartbeat, and increased blood sugar levels. These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant and are being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before adjusting the dose, your doctor may assess your child's baseline serum caffeine levels if they were born to a mother who consumes caffeine.

Uses of Cafneon 40 mg Injection 2 ml

Cafneon 40 mg Injection 2 ml is commonly used to<br/> 1. Treat prematurity apnea:<br/>Caffeine citrate is most commonly used to treat premature infants, particularly those born preterm. Premature babies, particularly those born before 28 weeks of gestation, may experience pauses in breathing lasting more than 20 seconds (apnea). This is known as apnea of prematurity, and caffeine citrate is used to stimulate the respiratory centre in the brain, hence improving breathing and decreasing apnea episodes.<br/>2. Respiratory stimulation:<br/>Cafneon 40 mg Injection 2 ml works as a central respiratory stimulant, which means it can be beneficial in instances when respiratory function is limited, particularly in preterm infants with underdeveloped respiratory systems.<br/>3. Improvement of Diuresis:<br/>Caffeine is a moderate diuretic, but this is not the primary reason for its usage in therapeutic settings.<br/>4. Treatment for Neonatal Respiratory Depression:<br/>Caffeine citrate may be utilised in newborns with respiratory depression, particularly when it is associated with disorders such as hypoxia or birth asphyxia.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Cafneon 40 mg Injection 2 ml should be administered by a nurse or a doctor.• Do not self-administer.

Medicinal Benefits

Cafneon 40 mg Injection 2 ml contains Caffeine Citrate as an active ingredient, which belongs to the central nervous system (CNS) stimulants class. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow.

How Cafneon 40 mg Injection 2 ml Works

Cafneon 40 mg Injection 2 ml contains Caffeine Citrate, which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Cafneon 40 mg Injection 2 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Cafneon 40 mg Injection 2 ml out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cafneon 40 mg Injection 2 ml
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Identify the medicine causing acidosis and talk to your doctor whether it can be discontinued or substituted with other medicine.
  • If you experience symptoms of acidosis like rapid breathing, confusion, overtiredness or nausea, contact your doctor immediately.
  • Your doctor may recommend dietary changes like changes in potassium intake based on the type of acidosis.
  • Track your bowel movements and tell your doctor.
  • Eat small meals of plain food.
  • Avoid fatty and spicy food.
  • Get plenty of rest and manage stress.
  • Drink plenty of water.
  • Avoid solid food if symptoms get worse.
  • Consult the doctor if you have severe pain or vomiting or if your condition persists or worsens.

What if I have taken an overdose of Cafneon 40 mg Injection 2 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include anxiety, stomach pain, irregular/fast heartbeat, seizures, and trouble sleeping. If your newborn experiences these symptoms or if you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. Cafneon 40 mg Injection 2 ml should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.

Drug-Drug Interactions

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CaffeineIsocarboxazid
Critical
CaffeinePhenelzine
Critical

Drug-Drug Interactions

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CaffeineIsocarboxazid
Critical
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafneon 40 mg Injection 2 ml with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafneon 40 mg Injection 2 ml with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafneon 40 mg Injection 2 ml with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Coadministration of tranylcypromine with Cafneon 40 mg Injection 2 ml can in cause severe high blood pressure.

How to manage the interaction:
Taking Cafneon 40 mg Injection 2 ml with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineEsketamine
Severe
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Esketamine can cause increase in blood pressure and using it with Cafneon 40 mg Injection 2 ml may increase the risk.

How to manage the interaction:
Although there is a possible interaction between Cafneon 40 mg Injection 2 ml and Esketamine, it can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting your doctor.
CaffeineDipyridamole
Severe
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Concomitant use of Cafneon 40 mg Injection 2 ml with dipyridamole may decrease the effects of dipyridamole.

How to manage the interaction:
Although there is an interaction, Cafneon 40 mg Injection 2 ml can be taken with dipyridamole if prescribed by the doctor. Avoiding Cafneon 40 mg Injection 2 ml for 12 to 24 hours before dipyridamole administration is advised.
CaffeineBupropion
Severe
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Bupropion and Cafneon 40 mg Injection 2 ml can increase blood pressure. Concomitant use may have additive effects.

How to manage the interaction:
Although there is an interaction, Cafneon 40 mg Injection 2 ml can be taken with bupropion if prescribed by the doctor. Regular monitoring of blood pressure is advised.
CaffeineCocaine
Severe
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Coadministration of Cafneon 40 mg Injection 2 ml with cocaine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Cafneon 40 mg Injection 2 ml can be taken with cocaine if prescribed by the doctor. However, contact your doctor if you experience dizziness, lightheadedness, palpitations, and shortness of breath. Do not discontinue using any medication without contacting a doctor.
CaffeineTizanidine
Severe
How does the drug interact with Cafneon 40 mg Injection 2 ml:
Coadministration of Cafneon 40 mg Injection 2 ml with Tizanidine may increase the blood levels and effects of tizanidine. This may cause excessive blood pressure, especially when rising from a sitting or lying position.

How to manage the interaction:
Although there is an interaction, Cafneon 40 mg Injection 2 ml can be taken with tizanidine if prescribed by the doctor. Contact your doctor if you experience dizziness, excessive sweating, or palpitations. Do not stop using any medicine without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Caution

Cafneon 40 mg Injection 2 ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

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Driving

Not applicable

-

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Liver

Caution

Cafneon 40 mg Injection 2 ml should be used with caution in infants with impaired liver function.

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Kidney

Caution

Cafneon 40 mg Injection 2 ml should be used with caution in infants with impaired kidney function.

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Children

Consult your doctor

Cafneon 40 mg Injection 2 ml is intended for use in premature newborns and neonates. Consult your doctor for more information.

Have a query?

FAQs

Cafneon 40 mg Injection 2 ml is used in the treatment of apnea of premature newborns.

Cafneon 40 mg Injection 2 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory center, sensitizing it to hypercapnia. Thereby Cafneon 40 mg Injection 2 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

No, it is intended to treat apnea in premature newborns and neonates.

The dosage is determined by your babys weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - CAF0051

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:20 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/20793s1lbl.pdf
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