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compositionComposition:IRINOTECAN-20MG/ML
prescription
Prescription Medicine
info
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Caitrino-CRC 100 mg Injection 5 ml is used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). It contains Irinotecan, which works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells cannot divide. As a result, Irinotecan inhibits cancer cell division and growth.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IRINOTECAN-20MG/ML

Manufacturer/Marketer :

Caitlin Oncology

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Caitrino-CRC 100 mg Injection 5 ml

Caitrino-CRC 100 mg Injection 5 ml is a prescription medication used to treat advanced cancer of the colon or rectum. It is typically prescribed when other treatments have not produced the desired results or as part of a primary treatment plan. This medicine is designed to help slow or stop the growth of cancer cells in the body.

This medicine is typically injected as an intravenous infusion once every two to three weeks, depending on your treatment plan. Consistency is vital, as keeping your scheduled appointments ensures the medication works continuously to target cancer cells. Since it is injected directly into a vein by a healthcare provider, food intake does not affect how the medication is absorbed, but eating light meals on treatment days and staying well-hydrated can improve your comfort. Making simple lifestyle adjustments, like drinking extra fluids and eating smaller, more frequent meals, can support your body during therapy.

While this medicine is highly effective, it can cause common side effects such as nausea, hair loss, and temporary tiredness. However, you must seek immediate medical attention if you experience severe, watery diarrhoea or signs of a serious infection, such as a high fever or chills.

Talk to your doctor before starting this treatment if you have a history of liver damage, asthma, or kidney disease. Do not take this if you have severe bone marrow failure, severe inflammatory bowel disease, or high levels of bilirubin in your blood.

This medication can interact with certain other medicines, herbal supplements like St. John's Wort, and alcohol, which may increase the risk of severe side effects or make the treatment less effective. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, you must consult your healthcare provider to discuss the specific risks and protective measures needed.

Uses of Caitrino-CRC 100 mg Injection 5 ml

Your doctor may prescribe Caitrino-CRC 100 mg Injection 5 ml to treat the following conditions:

  • Colorectal cancer (cancer of the colon or rectum): Caitrino-CRC 100 mg Injection 5 ml helps by targeting and slowing the growth of cancer cells in the large intestine or rectum, often used when other treatments have not worked or in combination with other chemotherapy drugs.
  • Advanced pancreatic cancer: In certain combination regimens, Caitrino-CRC 100 mg Injection 5 ml helps stop cancer cells from multiplying and spreading in pancreatic tissues.
  • Small cell lung cancer: In some clinical cases, it is used to help manage and treat advanced lung cancer by disrupting the replication of fast-growing cancer cells.

Key Benefits

Caitrino-CRC 100 mg Injection 5 ml helps slow the growth and spread of advanced cancer cells, supporting better disease control and helping relieve symptoms caused by tumour growth. It is often used as part of combination chemotherapy to improve treatment outcomes.

  • Helps slow cancer progression: Inhibits the growth and spread of cancer cells, helping control advanced disease and delay tumour progression.
  • Relieves cancer-related symptoms: By reducing tumour growth, it may help ease symptoms such as pain, abdominal discomfort, bowel obstruction, or pressure caused by the tumour.
  • Enhances combination therapy: Works alongside other chemotherapy medicines to improve the overall effectiveness of cancer treatment in appropriate patients.
  • Supports quality of life: Better disease control may help reduce cancer-related symptoms, maintain physical function, and improve overall well-being during treatment.
Side effects of Caitrino-CRC 100 mg Injection 5 ml
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Maintaining adequate hydration will help you control your magnesium levels and improve your general health.
  • Maintain a diet high in magnesium-rich foods such as spinach, almonds, chickpeas and brown rice.
  • Limit your alcohol intake because too much of it lowers your magnesium levels.
  • Plan blood testing on a regular basis to monitor magnesium levels.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • If you notice symptoms like redness, rash, itching, nausea, chills, fever, chest pain, or trouble breathing, after your infusion, contact your healthcare provider right away to stop the medication.
  • Your doctor may treat you with medications like antihistamines, corticosteroids, fever reducers, anti-nausea drugs, and oxygen therapy; they may also administer epinephrine if you have a severe, life-threatening allergic reaction.
  • Your vital signs will be checked regularly, and depending on how severe the reaction is, your infusion may be slowed down or stopped for good.
  • Drink lots of fluids before, during, and after your infusion to help your body clear out any substances causing a reaction.
  • Try to rest and relax before and after your infusion to reduce stress and help your body recover.
  • Eat a balanced diet to support your immune system and overall well-being.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Caitrino-CRC 100 mg Injection 5 ml will be administered by a trained healthcare professional.
  • Do not self-administer.

How Caitrino-CRC 100 mg Injection 5 ml Works

Caitrino-CRC 100 mg Injection 5 ml contains irinotecan, which works by blocking a specific protein in the body called topoisomerase I. This protein is essential for cancer cells to copy their DNA and multiply. By blocking this protein, the medicine causes damage to the DNA of the cancer cells, preventing them from dividing and ultimately causing them to die. Because cancer cells divide much faster than normal cells, they are highly sensitive to this blockage, which helps shrink tumours and control the spread of the disease.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Caitrino-CRC 100 mg Injection 5 ml.

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Pregnancy

Unsafe

Caitrino-CRC 100 mg Injection 5 ml should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Caitrino-CRC 100 mg Injection 5 ml should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Caitrino-CRC 100 mg Injection 5 ml can make you dizzy or impair your vision, especially in the first 24 hours after taking it. Do not drive or operate machinery until you know how this drug affects you.

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Liver

Caution

Caitrino-CRC 100 mg Injection 5 ml should be used with caution if you have liver disease. Inform your doctor before receiving the Caitrino-CRC 100 mg Injection 5 ml if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

It is not recommended for use in patients on dialysis. Inform your doctor before receiving the Caitrino-CRC 100 mg Injection 5 ml if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Safety and effectiveness in children have not been established. Hence, use is not recommended.

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Heart

Caution

Caitrino-CRC 100 mg Injection 5 ml may be used in patients with heart problems, but it requires close monitoring due to risks like bradycardia and dehydration-related cardiac complications. Medical supervision is essential to ensure safe administration.

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Geriatrics

Caution

Geriatric patients can receive irinotecan injections, but they may be more prone to severe side effects like diarrhea. Dose adjustments and close medical supervision are often necessary to ensure safe treatment.

What if I have taken an overdose of Caitrino-CRC 100 mg Injection 5 ml

Since this medication is prepared and given by trained medical staff, an overdose is highly unlikely. However, if you suspect an error or experience severe symptoms immediately after your infusion, notify your medical team right away.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of clear fluids, such as water, oral rehydration solutions, or clear broths, to replace lost fluids, especially if you develop diarrhoea during treatment.
  • Eat small, easy-to-digest meals: Choose bland, low-fibre foods such as bananas, white rice, applesauce, plain toast, or crackers if you experience nausea or diarrhoea. Gradually return to your normal diet as your symptoms improve.
  • Avoid foods that worsen stomach upset: Limit dairy products (if they aggravate symptoms), caffeine, alcohol, and spicy, greasy, or highly seasoned foods, as these may increase nausea or diarrhoea.
  • Reduce your risk of infections: Wash your hands frequently, maintain good personal hygiene, and avoid close contact with people who have contagious illnesses, as this medicine may temporarily lower your white blood cell count and increase your risk of infections.
health query

Have a query?

How Soon It Starts Working

The time required for Caitrino-CRC 100 mg Injection 5 ml to start to work: The exact onset time of Caitrino-CRC 100 mg Injection 5 ml has not been clinically established. The time for which the effects of Caitrino-CRC 100 mg Injection 5 ml last: The duration of Caitrino-CRC 100 mg Injection 5 ml effect is unknown.

What if you forget to take Caitrino-CRC 100 mg Injection 5 ml

Because this medicine is given in a clinical setting by healthcare professionals, missing a dose is rare. If you miss or have to cancel an appointment for your infusion, contact your clinic or doctor immediately to reschedule your treatment and keep your therapy on track.

Storage

•Unopened vials of Caitrino-CRC 100 mg Injection 5 ml should be stored at room temperature, between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Manage diarrhoea promptly: Monitor your bowel movements closely. Your doctor may prescribe an anti-diarrhoeal medicine, such as loperamide, to keep at home. Start taking it at the first sign of loose stools and contact your healthcare team if diarrhoea is severe or persistent.
  • Report injection site problems immediately: During or after the infusion, tell your nurse immediately if you experience burning, pain, swelling, redness, or a cold sensation at the injection site, as leakage of the medicine outside the vein can damage surrounding tissues.
  • Avoid medicines that increase bleeding risk: Do not take aspirin, NSAIDs (such as ibuprofen), or other blood-thinning medicines unless your oncologist specifically advises you to, as Caitrino-CRC 100 mg Injection 5 ml may lower your platelet count and increase the risk of bleeding.
  • Avoid live vaccines: Do not receive live vaccines during treatment unless your doctor specifically recommends them, as your immune system may be weakened and unable to respond safely.
  • Use effective contraception: Use reliable birth control during treatment and for the period recommended by your doctor after your final dose, as Caitrino-CRC 100 mg Injection 5 ml can harm an unborn baby. Inform your doctor immediately if you or your partner become pregnant during treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong liver enzyme inducers (such as carbamazepine, phenytoin, or phenobarbital): May decrease the level of Caitrino-CRC 100 mg Injection 5 ml in your body, making the treatment less effective.
  • Strong liver enzyme inhibitors (such as ketoconazole, clarithromycin, or atazanavir): May significantly increase the level of Caitrino-CRC 100 mg Injection 5 ml in your body, increasing the risk of severe side effects like low blood counts and severe diarrhea.
  • St. John's Wort: Can lower the effectiveness of this medication and should be avoided during treatment.
IrinotecanKetoconazole
Critical
IrinotecanClarithromycin
Severe

Drug-Drug Interactions

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IrinotecanKetoconazole
Critical
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Using Caitrino-CRC 100 mg Injection 5 ml together with ketoconazole can increase the risk of side effects.

How to manage the interaction:
Taking Ketoconazole with Caitrino-CRC 100 mg Injection 5 ml is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.
IrinotecanClarithromycin
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
When Clarithromycin is taken with Caitrino-CRC 100 mg Injection 5 ml, it can interfere with the normal clearance of Caitrino-CRC 100 mg Injection 5 ml from the body. This may increase side effects.

How to manage the interaction:
Although taking Caitrino-CRC 100 mg Injection 5 ml and Clarithromycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - feeling sick, throwing up, stomach pain, diarrhea, not enough water in your body sores in your mouth, not enough red blood cells, bleeding problems, looking pale, feeling tired, feeling dizzy or passing out, having a fever or chills, a sore throat, muscle pain, trouble breathing, losing weight, feeling pain, or bleeding or bruising - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
IrinotecanClozapine
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Co-administration of Caitrino-CRC 100 mg Injection 5 ml with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
There may be a possibility of interaction between Caitrino-CRC 100 mg Injection 5 ml and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, it is important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
IrinotecanCladribine
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Combining Cladribine with Caitrino-CRC 100 mg Injection 5 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Caitrino-CRC 100 mg Injection 5 ml and Cladribine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
IrinotecanEtanercept
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
When Etanercept is used with Caitrino-CRC 100 mg Injection 5 ml, the risk or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Caitrino-CRC 100 mg Injection 5 ml, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IrinotecanFosphenytoin
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
When Fosphenytoin is taken with Caitrino-CRC 100 mg Injection 5 ml, it can make the body process Caitrino-CRC 100 mg Injection 5 ml faster. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Fosphenytoin and Caitrino-CRC 100 mg Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting your doctor.
IrinotecanMifepristone
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Co-administration of Caitrino-CRC 100 mg Injection 5 ml with mifepristone may significantly increase the effect of Caitrino-CRC 100 mg Injection 5 ml.

How to manage the interaction:
Taking Caitrino-CRC 100 mg Injection 5 ml with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as nausea, vomiting, constipation, abdominal cramping, confusion, dizziness, lightheadedness, fainting, muscle weakness, muscle cramps, numbness or tingling, rapid heartbeat, or chest pain. Do not discontinue any medications without consulting a doctor.
IrinotecanCeritinib
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Taking ceritinib with Caitrino-CRC 100 mg Injection 5 ml may increase the risk of infection and other side effects.

How to manage the interaction:
Although taking Caitrino-CRC 100 mg Injection 5 ml and Ceritinib together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
IrinotecanInfliximab
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
When Caitrino-CRC 100 mg Injection 5 ml is taken with Infliximab, it can make the body process Caitrino-CRC 100 mg Injection 5 ml faster. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Caitrino-CRC 100 mg Injection 5 ml can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
IrinotecanRitonavir
Severe
How does the drug interact with Caitrino-CRC 100 mg Injection 5 ml:
Taking Ritonavir with Caitrino-CRC 100 mg Injection 5 ml can increase the risk of side effects.

How to manage the interaction:
Although taking Caitrino-CRC 100 mg Injection 5 ml and Ritonavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May interfere with how your liver breaks down this medicine, potentially increasing toxic side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Caitrino-CRC 100 mg Injection 5 ml is used to treat Colorectal cancer.
Caitrino-CRC 100 mg Injection 5 ml contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can't divide. As a result, Irinotecan inhibits cancer cell division and growth.
Caitrino-CRC 100 mg Injection 5 ml should not be used in patients with pulmonary diseases. So, inform your doctor if you have pulmonary disorders (lung problems).
While taking Caitrino-CRC 100 mg Injection 5 ml, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Caitrino-CRC 100 mg Injection 5 ml.
The live vaccine may not work while on treatment with Caitrino-CRC 100 mg Injection 5 ml. Only have immunizations/vaccinations after talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Irinotecan therapy may lead to Neutropenia (an unusually low number of neutrophil cells). Your doctor will order laboratory testing on a regular basis before and during your treatment.
You should know that this medicine may reduce fertility in both men and women. Discuss the risks of taking an irinotecan injection with your doctor.
You are recommended to take the advice of your doctor before taking Caitrino-CRC 100 mg Injection 5 ml. As Caitrino-CRC 100 mg Injection 5 ml is not used during pregnancy.
The common side effects of Caitrino-CRC 100 mg Injection 5 ml are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). If any of these side effects persist or worsen, please consult your doctor.
This medicine can irritate the digestive tract and affect the nerves that control bowel movements. This can cause early diarrhoea (during the infusion) or late diarrhoea (days after). Talk to your doctor about how to manage this with anti-diarrhoea medications.
This medicine can cause dizziness, sleepiness, or temporary vision problems shortly after administration. It is safest to have someone else drive you home after your appointment. Talk to your doctor if you experience these symptoms.
Yes, temporary hair thinning or hair loss is a common side effect of this treatment. Your hair will typically start to grow back after your chemotherapy cycles are complete. Talk to your doctor if you have concerns about managing hair loss.
It is highly recommended to avoid alcohol during treatment. Alcohol can worsen nausea, increase dehydration, and put extra strain on your liver, which is already processing the medication. Talk to your doctor or pharmacist for guidance.
A fever (especially 38°C/100.4°F or higher) is a medical emergency during this treatment because your immune system may be weak. Contact your doctor or go to the nearest emergency room immediately. Talk to your doctor about monitoring your temperature.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A608043 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Nbk554441 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 020571S048Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Irinotecan hydrochloride trihydrate. 1995Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 18 Feb. 2020]Check here
  6. Hikma Pharmaceuticals USA Inc. Irinotecan hydrochloride Injection. Dailymed. [Revised in June 2020]. [Accessed on 22nd March 2023]Check here
  7. Hospira UK Limited. Irinotecan Hydrochloride 20 mg/mL concentrate for solution for infusion. European Medicines Compendium. [Revised in December 2022]. [Accessed on 22nd March 2023]Check here

Country of origin

India

Manufacturer/Marketer address

FB Lane, Charminar East, Hyderabad
Other Info - CAI0040
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