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compositionComposition:NIFEDIPINE-20MG
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Prescription Medicine
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CARDULES RETARD 20MG CAPSULE is used to treat high blood pressure (hypertension). It is also used to reduce strokes and chest pain (angina) caused by the blockage of the arteries. In addition to this, it is also used to treat preterm labour. It contains Nifedipine, which works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects, such as low blood pressure, headache, slow heartbeat, dizziness, and rash, in some cases. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NIFEDIPINE-20MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About CARDULES RETARD 20MG CAPSULE

CARDULES RETARD 20MG CAPSULE is a prescription medication used to treat high blood pressure (hypertension) and to prevent chronic chest pain (angina). It contains nifedipine, which works by relaxing your blood vessels, making it easier for your heart to pump blood throughout your body. By keeping your blood pressure within a healthy range, it helps reduce the risk of serious cardiovascular events like strokes and heart attacks.

To get the most benefit, you must take CARDULES RETARD 20MG CAPSULE consistently every day at the same time, exactly as prescribed by your doctor. You can take this medication with or without food, but you should stick to the same routine daily to keep drug levels steady. Incorporating heart-healthy lifestyle habits, such as eating a low-salt diet and getting regular physical activity, can significantly improve your treatment results.

While taking CARDULES RETARD 20MG CAPSULE, you may experience common, mild side effects such as headaches, flushing, or mild swelling in your ankles and feet. However, if you experience rare but serious symptoms, such as an exceptionally rapid or pounding heartbeat, severe dizziness, or worsening chest pain, you must contact your doctor right away.

Talk to your doctor before starting this medicine if you have a history of liver damage, heart failure, or severe narrowing of your heart valves. Do not take this medicine if you are allergic to CARDULES RETARD 20MG CAPSULE or any of its ingredients, or if you have recently experienced a heart attack.

CARDULES RETARD 20MG CAPSULE can interact with alcohol, which may cause your blood pressure to drop too low and make you feel dizzy. It also interacts with certain other blood pressure medicines, some antibiotics, and grapefruit juice, which can alter how the drug works in your body. If you are pregnant, planning to breastfeed, or are an older adult, consult your doctor or pharmacist to ensure CARDULES RETARD 20MG CAPSULE is safe for your specific situation.

Uses of CARDULES RETARD 20MG CAPSULE

CARDULES RETARD 20MG CAPSULE is used to improve blood flow and reduce the workload on the heart and blood vessels. The detailed uses of CARDULES RETARD 20MG CAPSULE are as follows: 

  • High blood pressure (hypertension): CARDULES RETARD 20MG CAPSULE relaxes and widens blood vessels, which lowers blood pressure and reduces the overall workload on your heart.
  • Chronic stable angina: This medicine helps prevent chest pain by increasing blood flow and oxygen supply to your heart muscle during physical exertion.
  • Vasospastic angina: By preventing spasms or sudden tightening of the coronary arteries, CARDULES RETARD 20MG CAPSULE keeps blood flowing steadily to your heart to avoid sudden chest pain.

Key Benefits

CARDULES RETARD 20MG CAPSULE helps improve blood flow and reduce the workload on the heart, supporting better cardiovascular health and helping you stay active in your daily life. The key benefits of CARDULES RETARD 20MG CAPSULE include: 

  • Fewer chest pain episodes: Consistent use of CARDULES RETARD 20MG CAPSULE allows you to perform daily physical activities and moderate exercise with a reduced risk of chest pain, helping you stay active and comfortable.
  • Long-term heart protection: By keeping your blood pressure under control, this medicine lowers your chances of experiencing life-threatening conditions like strokes, heart attacks, or kidney damage.
  • Better daily stamina: When your heart does not have to work as hard to pump blood through narrow vessels, you may feel less fatigued and have more energy for your daily routines.

Directions for Use

Always follow your doctor's exact instructions when taking this medication. To take CARDULES RETARD 20MG CAPSULE safely and effectively, keep the following steps in mind:

  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it, especially if it is an extended-release tablet, as this can cause too much of the drug to be released into your body at once.
  • Take your dose at the same time every day to maintain a steady level of the medicine in your bloodstream.
  • You may take this medicine with or without food, but be consistent with your choice every day.

Never adjust your dose or stop taking this medicine without first consulting your doctor, even if you feel completely fine.

How CARDULES RETARD 20MG CAPSULE Works

CARDULES RETARD 20MG CAPSULE contains nifedipine and belongs to a group of medications known as calcium channel blockers. Your blood vessels and heart muscles need calcium to contract and squeeze shut. This medicine works by blocking calcium from entering the muscle cells of your heart and blood vessels. When calcium entry is blocked, these muscles relax. This causes your blood vessels to widen and relax, which naturally lowers your blood pressure. It also dilates the arteries that supply your heart with blood, ensuring your heart muscle gets plenty of oxygen. This increased oxygen supply is what prevents chest pain from occurring during exercise or daily activities.
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Alcohol

Unsafe

Alcohol consumption may increase the occurrence of unpleasant side effects.

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Pregnancy

Consult your doctor

If you are pregnant, think you may be pregnant, or plan to have a baby, consult your doctor for advice before taking this medicine. You may be able to use CARDULES RETARD 20MG CAPSULE, but only after special consideration by your doctor.

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Breast Feeding

Caution

Please do not take CARDULES RETARD 20MG CAPSULE without a doctor's advice, as it may pass through the breast milk.

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Driving

Caution

CARDULES RETARD 20MG CAPSULE may cause side effects like dizziness, which could affect your ability to drive. Hence, drive or operate machinery only when you are alert.

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Liver

Consult your doctor

There is limited information available on the use of CARDULES RETARD 20MG CAPSULE in patients with liver disease. Please consult your doctor.

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Kidney

Consult your doctor

CARDULES RETARD 20MG CAPSULE is probably safe to use in patients with kidney disease. Limited data available suggest that dose adjustment may not be needed in these patients. Please consult your doctor.

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Children

Unsafe

The safety and effectiveness of CARDULES RETARD 20MG CAPSULE have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

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Heart

Safe if prescribed

CARDULES RETARD 20MG CAPSULE is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision

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Geriatrics

Caution

CARDULES RETARD 20MG CAPSULE should be taken with caution in geriatric patients. Please consult your doctor before using CARDULES RETARD 20MG CAPSULE.

What if I have taken an overdose of CARDULES RETARD 20MG CAPSULE

Do not take more than the prescribed dose of CARDULES RETARD 20MG CAPSULE as it may cause serious side effects resulting in too low blood pressure, causing dizziness, especially on standing, and a fast or slow heartbeat. Other symptoms of overdose include an increase in blood sugar level, an increase in the acidity of blood, low blood oxygen levels, swelling in the lungs, and disturbances in consciousness, possibly leading to unconsciousness. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Follow a low-salt diet: Reducing the amount of sodium in your meals helps lower your blood pressure and can reduce fluid retention and ankle swelling.
  • Avoid grapefruit and grapefruit juice: Grapefruit contains compounds that slow down your body's ability to break down CARDULES RETARD 20MG CAPSULE. This can cause the medicine to build up in your system, increasing the risk of serious side effects.
  • Engage in safe physical activity: Consistent, moderate exercise like walking or swimming helps strengthen your heart. Always discuss new exercise routines with your doctor, especially if you have chest pain.
  • Limit your alcohol intake: Drinking alcohol while taking this medicine can lower your blood pressure excessively, making you feel severely dizzy or lightheaded.
  • Quit smoking: Smoking damages and narrows your blood vessels, which directly opposes the beneficial blood-flow effects of this medicine.

Have a query?

How Soon It Starts Working

  • The time required for CARDULES RETARD 20MG CAPSULE to start to work: The time required for CARDULES RETARD 20MG CAPSULE to start to work is 30 to 120 minutes after administration.
  • The time for which the effects of CARDULES RETARD 20MG CAPSULE last: The effect of CARDULES RETARD 20MG CAPSULE lasts for 4 to 8 hours.

What if you forget to take CARDULES RETARD 20MG CAPSULE

If you forget to take a dose of CARDULES RETARD 20MG CAPSULE, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

• Store the medication at room temperature, ideally between 68°F and 77°F (20°C to 25°C). • Keep it in a dry place and avoid areas of high humidity, such as bathroom cabinets

Drug Warnings

  • Change positions slowly: Sit or stand up gradually from a lying position to avoid sudden drops in blood pressure that can cause dizziness or falls.
  • Monitor your blood pressure: Check your blood pressure regularly at home and keep a written record to share with your healthcare provider during checkups.
  • Watch for empty tablet shells: If you are taking an extended-release form of this medicine, you may notice what looks like an empty tablet shell in your stool. This is normal, as your body absorbs the medicine and passes the empty outer coating.
  • Avoid driving if you feel dizzy: Do not drive, ride a bicycle, or operate heavy machinery until you are certain how this medication affects your alertness.
  • Inform medical teams before surgery: Always tell your surgeon, dentist, or anesthesiologist that you are taking CARDULES RETARD 20MG CAPSULE before any medical procedures, as it can interact with other drugs used during surgery.

Drug-Drug Interactions

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Drug-Drug Interactions


Inform your doctor if you are taking any of the following medicines, as they may interact with CARDULES RETARD 20MG CAPSULE:

  • Other Blood Pressure Medicines: Combining CARDULES RETARD 20MG CAPSULE with other blood pressure-lowering medicines, such as beta-blockers or ACE inhibitors, may cause your blood pressure to drop too low.
  • Certain Antifungals and Antibiotics: Medicines such as ketoconazole and erythromycin may increase the levels of CARDULES RETARD 20MG CAPSULE in the body, raising the risk of side effects.
  • Antiseizure Medicines: Antiseizure medicines such as carbamazepine may reduce the effectiveness of CARDULES RETARD 20MG CAPSULE by increasing how quickly it is broken down in the body.


Drug-Food Interactions


Certain foods and beverages may affect how CARDULES RETARD 20MG CAPSULE works or increase the risk of side effects. Examples include: 

  • Grapefruit and Grapefruit Juice: Avoid grapefruit and grapefruit juice while taking CARDULES RETARD 20MG CAPSULE, as they may significantly increase the amount of medicine in your bloodstream and cause a sudden drop in blood pressure.


Drug-Disease Interactions


Inform your doctor if you have a history of the following conditions before taking CARDULES RETARD 20MG CAPSULE, as it may worsen your condition or require closer monitoring.

  • Severe Liver Disease: If you have severe liver damage, your body may not process CARDULES RETARD 20MG CAPSULE effectively, and your doctor may need to monitor you closely or adjust your treatment.
  • Aortic Stenosis: Use this medicine with caution if you have severe narrowing of the aortic heart valve, as it may worsen your condition.
  • Heart Failure: CARDULES RETARD 20MG CAPSULE should be used cautiously in people with heart failure, as it may aggravate symptoms in some cases.
     

Drug-Drug Interactions

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How does the drug interact with Cardules Retard 20mg Capsule:
Coadministration of Cardules Retard 20mg Capsule with Carbamazepine can reduce the blood levels of Cardules Retard 20mg Capsule, which may make the medication less effective.

How to manage the interaction:
Taking Cardules Retard 20mg Capsule with Carbamazepine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cardules Retard 20mg Capsule:
Coadministration of Cardules Retard 20mg Capsule with Rifabutin may significantly reduces the blood levels of Cardules Retard 20mg Capsule which may make the medication less effective.

How to manage the interaction:
Taking Cardules Retard 20mg Capsule with Rifabutin together is usually avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NifedipineFosphenytoin
Severe
How does the drug interact with Cardules Retard 20mg Capsule:
When Fosphenytoin is taken with Cardules Retard 20mg Capsule, the amount of Fosphenytoin in the blood can be reduced.

How to manage the interaction:
Co-administration of Fosphenytoin with Cardules Retard 20mg Capsule can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like sweating, dizziness, confusion, drowsiness, sweating, chest pain or tightness, palpitations, headache, nausea, or vomiting, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cardules Retard 20mg Capsule:
Coadministration of Phenytoin and Cardules Retard 20mg Capsule may decrease the blood levels of Cardules Retard 20mg Capsule, which may make Cardules Retard 20mg Capsule less effective.

How to manage the interaction:
Taking Cardules Retard 20mg Capsule with Phenytoin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice headache, fatigue, palpitations, shortness of breath, edema, or constipation, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
NifedipineDolasetron
Severe
How does the drug interact with Cardules Retard 20mg Capsule:
Using Dolasetron together with Cardules Retard 20mg Capsule can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Cardules Retard 20mg Capsule with Dolasetron can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like an irregular heart rhythm, sudden dizziness, lightheadedness, fainting, or irregular heartbeat, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cardules Retard 20mg Capsule:
Cardules Retard 20mg Capsule's blood levels can rise when itraconazole and Cardules Retard 20mg Capsule are taken together.

How to manage the interaction:
Cardules Retard 20mg Capsule and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you develop dizziness or fainting, unexpected swelling of the hands, ankles, or feet, chest pain, or difficulty breathing, consult a doctor. Never discontinue taking a medication without consulting a doctor.
How does the drug interact with Cardules Retard 20mg Capsule:
Phenobarbital can drastically lower Cardules Retard 20mg Capsule levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Cardules Retard 20mg Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cardules Retard 20mg Capsule:
Coadministration of Cardules Retard 20mg Capsule with Modafinil can reduce the levels of Cardules Retard 20mg Capsule in the body. This may lead to low treatment outcomes.

How to manage the interaction:
Taking Cardules Retard 20mg Capsule with Modafinil together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of increased heart rate, muscle cramps, tremors, cough, fever, nausea, vomiting, fatigue, edema, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NifedipineRifapentine
Severe
How does the drug interact with Cardules Retard 20mg Capsule:
Coadministration of Cardules Retard 20mg Capsule with Rifapentine can reduce the metabolism and increase the levels of Cilostazol in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Cardules Retard 20mg Capsule with Rifapentine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of drowsiness, dizziness, confusion, headache, fever, chills, excessive sweating, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NifedipineVenetoclax
Severe
How does the drug interact with Cardules Retard 20mg Capsule:
Using Venetoclax together with Cardules Retard 20mg Capsule may significantly increase the blood levels and effects of Venetoclax.

How to manage the interaction:
Although there is a possible interaction between Cardules Retard 20mg Capsule and Venetoclax, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your blood cells. Your doctor can recommend other options that won't cause any problems. If you notice any of these symptoms - like feeling sick, kidney problems, or stomach issues - make sure to call a doctor right away. They can help you with things like tiredness, anemia, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

CARDULES RETARD 20MG CAPSULE is used to treat high blood pressure (hypertension). It works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Yes, CARDULES RETARD 20MG CAPSULE can cause a sudden drop in blood pressure, especially when you start taking CARDULES RETARD 20MG CAPSULE. To avoid a sudden drop, please get up gently when sitting down so as to avoid dizziness.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose, as this may increase the risk of side effects such as low blood pressure.
No, it is a prescription drug administered by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
CARDULES RETARD 20MG CAPSULE, if stopped abruptly, may lead to withdrawal symptoms. Before stopping CARDULES RETARD 20MG CAPSULE, consult your doctor; your dose will be lowered gradually to avoid any unpleasant side effects of CARDULES RETARD 20MG CAPSULE.
Yes, in some cases, CARDULES RETARD 20MG CAPSULE may cause headaches. Headaches should usually go away after the first week of taking nifedipine. Talk to your doctor if they last longer than a week or are severe.
CARDULES RETARD 20MG CAPSULE belongs to a group of medications called Calcium channel blockers or calcium antagonists. However, research reports that nifedipine has an apparent diuretic and natriuretic effect on healthy volunteers.
CARDULES RETARD 20MG CAPSULE is generally safe to take for a long time. In fact, it works best when taken for a long time. If you experience any adverse events, consult a doctor immediately.
In rare cases, CARDULES RETARD 20MG CAPSULE can lead to Acute Kidney Injury (AKI) by causing deleterious kidney hemodynamic alterations.
A very rare but known adverse effect of CARDULES RETARD 20MG CAPSULE is drug-induced liver injury. Seek medical attention if you experience any difficulty while using CARDULES RETARD 20MG CAPSULE.
Nifedipine may impair insulin secretion at high glucose levels in patients with non-insulin-dependent mellitus. Seek medical attention if you experience any symptoms.
Nifedipine passes into breast milk in very small amounts and has not been known to cause side effects in breastfed babies. If you notice that your baby is not feeding as regularly, or if you have any other concerns, talk to your doctor.
In some cases, CARDULES RETARD 20MG CAPSULE may cause palpitations. Typically, these do not require medical attention and usually resolve gradually over time. However, if these are persistent, contact your doctor.
Yes. Healthy lifestyle habits can improve blood pressure control and heart health. These include eating a balanced diet low in salt, exercising regularly, maintaining a healthy weight, quitting smoking, limiting alcohol intake, managing stress, and following your prescribed treatment plan.
It depends on your individual medical condition and response to the medication. Your doctor will determine the appropriate duration of treatment based on your specific needs.
Common side effects of CARDULES RETARD 20MG CAPSULE may include low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Most of these side effects of CARDULES RETARD 20MG CAPSULE do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
No, you should swallow the tablets whole. Crushing, chewing, or breaking them, especially the extended-release forms, can cause the entire dose of the medication to be released into your body at once, which increases the risk of severe side effects. Talk to your doctor or pharmacist if you have trouble swallowing.
For high blood pressure, CARDULES RETARD 20MG CAPSULE starts lowering your pressure within a few hours, though it can take a few weeks of daily use to see the full effect. For preventing chest pain, it must be taken consistently every day and will not stop an active attack. Talk to your doctor or pharmacist if you do not feel an improvement.
It is best to avoid or limit alcohol while taking this medicine. Alcohol can compound the blood pressure-lowering effect of CARDULES RETARD 20MG CAPSULE, causing severe dizziness, headache, or fainting. Talk to your doctor or pharmacist about your alcohol consumption.
This is normal for some extended-release versions of this medicine. The active medicine is absorbed through a special outer shell that does not dissolve in your body and is safely passed in your stool. There is no need to take an extra dose. Talk to your doctor or pharmacist if you are concerned.
Yes, mild ankle and foot swelling is a known side effect of CARDULES RETARD 20MG CAPSULE. This happens because the medicine relaxes your blood vessels, causing fluid to pool in your lower limbs. Elevating your legs when sitting can help. Talk to your doctor or pharmacist if the swelling becomes severe or painful.
No. Do not stop taking CARDULES RETARD 20MG CAPSULE without consulting your doctor, even if your blood pressure is well controlled. Stopping treatment suddenly may cause your blood pressure to rise again and increase the risk of heart-related complications. Your doctor will advise you if any changes to your treatment are needed.
CARDULES RETARD 20MG CAPSULE is sometimes used during pregnancy under careful medical supervision, but it may not be safe for everyone. If you are pregnant, planning a pregnancy, or breastfeeding, you must discuss the potential risks and benefits with your healthcare provider. Talk to your doctor or pharmacist for specific advice.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you need help setting up a dosing schedule.

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - CAR0006
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