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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Carmuther 100 Injection is used in the treatment of brain tumors. Carmuther 100 Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs. It contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

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Composition :

CARMUSTINE-100MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Carmuther 100 Injection

Carmuther 100 Injection is a chemotherapeutic medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Carmuther 100 Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs.

Carmuther 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Carmuther 100 Injection may cause certain side effects, such as nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Carmuther 100 Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Carmuther 100 Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carmuther 100 Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Carmuther 100 Injection

Treatment of Brain Tumors, Multiple Myeloma, Hodgkin's Disease and Non-Hodgkin's Disease

Directions for Use

Carmuther 100 Injection will be administered by a trained healthcare professional. Hence, do not self-administer. 

Medicinal Benefits

Carmuther 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

How Carmuther 100 Injection Works

Carmuther 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Carmuther 100 Injection

  • Nausea
  • Dizziness
  • Stomach upset
  • Headache
  • Vomiting
  • Pale skin
  • Tiredness
  • Loss of balance
  • Diarrhoea
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

What if I have taken an overdose of Carmuther 100 Injection

As Carmuther 100 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Carmuther 100 Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carmuther 100 Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. It is unknown whether Carmuther 100 Injection can be administered in children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking as it can lead to serious adverse effects.

Drug-Drug Interactions

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CarmustineBaricitinib
Severe
CarmustineClozapine
Severe

Drug-Drug Interactions

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CarmustineBaricitinib
Severe
How does the drug interact with Carmuther 100 Injection:
Coadministration of baricitinib and Carmuther 100 Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Carmuther 100 Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
CarmustineClozapine
Severe
How does the drug interact with Carmuther 100 Injection:
Combining Carmuther 100 Injection with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
Taking Clozapine with Carmuther 100 Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any of these symptoms - severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain during urination, contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CarmustineEtanercept
Severe
How does the drug interact with Carmuther 100 Injection:
When Etanercept is used with Carmuther 100 Injection, the severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Carmuther 100 Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CarmustineInfliximab
Severe
How does the drug interact with Carmuther 100 Injection:
When Carmuther 100 Injection is taken with Infliximab it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Carmuther 100 Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning while urinating, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
CarmustineLeflunomide
Severe
How does the drug interact with Carmuther 100 Injection:
Combining Carmuther 100 Injection with Leflunomide can increase the risk of negative side effects.

How to manage the interaction:
Co-administration of Carmuther 100 Injection with Leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - liver problems, complications, infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, dark urine or bleeding - contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
CarmustineCladribine
Severe
How does the drug interact with Carmuther 100 Injection:
Taking Cladribine with Carmuther 100 Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Carmuther 100 Injection, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Carmuther 100 Injection Substitute

Substitutes safety advice
  • CONSIUM 100MG INJECTION

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    4565.80per tablet
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  • Carnumax 100 Injection 1's

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    3936.00per tablet
  • Carstim 100 mg Combipack Injection 1's

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    4915.90per tablet
  • Nitsum 100 mg Injection 1's

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    3788.40per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Carmuther 100 Injection to prevent serious adverse effects.

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Pregnancy

Unsafe

Carmuther 100 Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Carmuther 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data is available on the effect of Carmuther 100 Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Carmuther 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Carmuther 100 Injection will be administered in the hospital setting. Hence, avoid driving.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Carmuther 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Carmuther 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Limited information is available for the use of Carmuther 100 Injection in children. Hence, it will be given to the children only if needed. If administered, careful monitoring of the child is needed.

FAQs

Carmuther 100 Injection is used to treat Brain Tumors, Multiple Myeloma, Hodgkin’s Disease and Non-Hodgkin’s Disease.

Carmuther 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

Carmuther 100 Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Carmuther 100 Injection is safe if taken at the prescribed dose and duration as advised by your doctor. It is effectively used in the treatment of brain tumours, multiple myeloma, Hodgkin's disease, and non-Hodgkin's disease. However, it may cause some side effects like nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection while taking it.

Carmuther 100 Injection is typically classified as an irritant among chemotherapy drugs. However, when given in high doses, it can have stronger effects and be considered a vesicant.

Yes, Carmuther 100 Injection works by preventing DNA and RNA transcription which is essential for protein synthesis.

The common side effects of Carmuther 100 Injection may include nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No's : 118 - 120, Road No. 6, Sy. No 342, ALEAP Industrial Estate, Pragathi Nagar, Kukatpally, Hyderabad - 500090, Telangana State, India
Other Info - CAR0934

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