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compositionComposition:CEFIXIME-200MG+OFLOXACIN-200MG
prescription
Prescription Medicine
info
Cefivoiz-O Tablet

Cefivoiz-O Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea. It contains Cefixime and Ofloxacin, which works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. It prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. It may cause some common side effects such as diarrhoea, indigestion, nausea, loose stools, abdominal pain, and vomiting.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFIXIME-200MG+OFLOXACIN-200MG

Manufacturer/Marketer :

Voizmed Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Cefivoiz-O Tablet

Cefivoiz-O Tablet is a combination antibiotic prescribed to treat a wide range of bacterial infections. This medicine is commonly used to clear infections in the urinary tract, lungs, and airways, as well as complex conditions like typhoid fever. It works by stopping bacterial growth and clearing the infection from your body.

To get the best results, you must take Cefivoiz-O Tablet consistently at the same times each day as directed by your healthcare provider. You can take this tablet with or without food, though taking it with a meal is often recommended to help prevent a mild upset stomach. Drinking plenty of water and getting extra rest will also help support your immune system during your recovery.

While taking Cefivoiz-O Tablet, some people may experience mild side effects like nausea, headache, or temporary changes in digestion. However, you must contact your doctor immediately if you develop serious symptoms, such as severe watery diarrhoea, sudden joint pain, or an unexpected skin rash. Seeking medical advice early ensures your treatment remains safe and effective.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver damage, tendon problems, or regular bowel inflammation. Do not take this if you have had an allergic reaction to cephalosporins, fluoroquinolones, or similar antibiotic medications in the past. Your doctor will evaluate your medical history to ensure this is the right option for you.

Certain medications, such as stomach antacids and iron supplements, can interfere with how your body absorbs Cefivoiz-O Tablet, so they should not be taken at the same time. You should avoid drinking alcohol during your treatment, as it can worsen dizziness and stomach discomfort. If you are pregnant, breastfeeding, or managing health conditions in your elderly years, always consult your healthcare provider before taking this medicine.
 

Uses of Cefivoiz-O Tablet

Cefivoiz-O Tablet may be prescribed for the following bacterial infections: 

  • Typhoid Fever: Cefivoiz-O Tablet helps clear the severe systemic bacterial infection responsible for typhoid, reducing high body temperature and restoring digestive comfort.
  • Urinary Tract Infections (UTIs): This medicine targets and eliminates bacteria causing painful, burning, or frequent urination, clearing the infection from the bladder or kidneys.
  • Respiratory Tract Infections: It treats infections like bronchitis and pneumonia by clearing bacteria from your lungs and airways, making it easier to breathe.
  • Prostate and Genital Infections: Cefivoiz-O Tablet penetrates deep into pelvic tissues to resolve bacterial infections and ease swelling or localised pain.
  • Abdominal Infections: It targets complex bacterial strains within the stomach and intestines, helping to relieve abdominal pain and prevent complications.
     

Key Benefits

Cefivoiz-O Tablet combines two antibiotics that work together to treat bacterial infections effectively. This combination helps eliminate infection-causing bacteria and supports a faster recovery.

  • Treats Bacterial Infections: Helps eliminate a wide range of bacteria responsible for infections affecting different parts of the body.
  • Provides Rapid Symptom Relief: Helps reduce infection-related symptoms such as fever, pain, inflammation, and discomfort as the infection improves.
  • Offers Broad-Spectrum Protection: The combination of two antibiotics helps target susceptible bacteria through different mechanisms, supporting effective treatment.
  • Supports Recovery: By helping control the infection, it may promote faster improvement in overall health and well-being.
  • Convenient At-home Treatment: The oral tablet formulation allows many infections to be treated effectively without the need for injectable antibiotics.
     

Directions for Use

To use this medicine safely and effectively, please follow these step-by-step instructions:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can alter how the medicine is absorbed in your body.
  • Take your doses at evenly spaced intervals throughout the day to keep a steady level of the medicine in your bloodstream.
  • Always complete the entire course of treatment prescribed by your doctor, even if your symptoms improve after a few days. Stopping
  • early can cause the remaining bacteria to multiply again.

Always follow your doctor's exact instructions regarding how many tablets to take and how many days to continue the treatment.
 

How Cefivoiz-O Tablet Works

This medicine contains cefixime and ofloxacin, which work together to help treat bacterial infections by attacking bacteria through different mechanisms. Cefixime is a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall, an essential structure that protects bacteria and maintains their shape. Without a properly functioning cell wall, the bacteria become weakened and eventually die. Ofloxacin is a fluoroquinolone antibiotic that works by blocking enzymes required for bacterial DNA replication, repair, and cell division. This prevents the bacteria from multiplying and spreading within the body. Together, these actions help eliminate susceptible bacteria, control the infection, and support recovery from bacterial illnesses.
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Alcohol

Unsafe

Avoid consumption of alcohol as it may worsen the side effects of Cefivoiz-O Tablet.

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Pregnancy

Unsafe

If you are pregnant or planning pregnancy, avoid taking Cefivoiz-O Tablet. If you become pregnant while on treatment with Cefivoiz-O Tablet, stop taking it and contact your doctor immediately.

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Breast Feeding

Unsafe

If you are a breastfeeding mother, avoid taking Cefivoiz-O Tablet.

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Driving

Unsafe

Cefivoiz-O Tablet may cause sleepiness, dizziness or may affect your eyesight. Therefore, avoid driving if you are not alert after taking Cefivoiz-O Tablet.

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Liver

Caution

Cefivoiz-O Tablet should be taken with caution in patients having a history of liver diseases/conditions. The doctor may suggest lower doses initially.

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Kidney

Caution

Cefivoiz-O Tablet to be taken with caution, especially in persons having a history of Kidney disorders. The doctor may initially suggest a lower dose of initially.

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Children

Unsafe

Cefivoiz-O Tablet is not recommended for children below 18 years of age.

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Heart

Unsafe

Cefivoiz-O Tablet is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Unsafe

Cefivoiz-O Tablet is not recommended for use in elderly patients as it can lead to side effects.

What if I have taken an overdose of Cefivoiz-O Tablet

Do not take more than the prescribed dose of Cefivoiz-O Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water throughout the day to support recovery and maintain hydration.
  • Support Gut Health: Consume probiotic-rich foods such as yoghurt or kefir a few hours after taking the medicine to help maintain healthy gut bacteria.
  • Be Mindful of Dairy and Calcium-Rich Products: The ofloxacin component may interact with calcium-containing foods and beverages, potentially reducing absorption. Consider taking dairy products, calcium-fortified drinks, or calcium supplements a few hours apart from your dose, and follow your doctor's or pharmacist's advice.
  • Protect Your Skin from Sunlight: Wear protective clothing and sunscreen when outdoors, as this medicine may increase sensitivity to sunlight.
  • Get Adequate Rest: Allow your body sufficient rest to support your immune system and recovery process.
     

Have a query?

How Soon It Starts Working

  • The time required for Cefivoiz-O Tablet to start to work: Cefivoiz-O Tablet ideally shows its action within 1 to 3 hours after administration.
  • The time for which the effects of Cefivoiz-O Tablet last: The effect of Cefivoiz-O Tablet lasts for 16 to 20 hours.

What if you forget to take Cefivoiz-O Tablet

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Avoid taking two doses at once.

Storage

•Store Cefivoiz-O Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original blister packaging to protect them from moisture and direct light.

Drug Warnings

  • Check Before Use: Inspect the blister pack before taking a dose and do not use the medicine if the packaging is damaged.
  • Use Caution During Activities: Avoid driving or operating machinery if you experience dizziness or lightheadedness after taking the medicine.
  • Report Joint or Tendon Problems: Contact your doctor immediately if you develop sudden joint pain, tendon pain, swelling, or a snapping sensation.
  • Monitor Treatment Response: Consult your doctor if your symptoms do not begin to improve within 3 to 4 days of starting treatment.
  • Do Not Share Your Medicine: Never share antibiotics with others, even if they have similar symptoms, as inappropriate antibiotic use may contribute to antibiotic resistance.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Cefivoiz-O Tablet: 

  • Antacids: Stomach remedies containing magnesium, aluminium, or calcium can lower the absorption of Cefivoiz-O Tablet. Take them at least 2 hours before or 2 hours after your antibiotic.
  • Blood Thinners: Taking this medicine with medications like warfarin may increase the risk of bleeding.
  • Pain Relievers (NSAIDs): Using certain pain relievers like ibuprofen with this medicine may increase the risk of central nervous system stimulation and seizures.
  • Iron and Zinc Supplements: Mineral supplements can bind with the medicine in your stomach, making it less effective.


Drug-Food Interactions

Certain foods and beverages may affect how Cefivoiz-O Tablet works or increase the risk of side effects: 

  • Dairy Products and Calcium-Rich Foods: The ofloxacin component may bind to calcium and reduce absorption. This interaction is mainly associated with ofloxacin rather than cefixime. If advised by your healthcare provider, take dairy products, calcium-fortified beverages, or calcium supplements a few hours apart from your dose.
  • Caffeine: This medicine can slow down how your body processes caffeine, which may lead to feelings of jitteriness, anxiety, or a rapid heart rate.


Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Cefivoiz-O Tablet, as dose adjustments or additional monitoring may be required: 

  • Myasthenia Gravis: This medicine can worsen muscle weakness, so it should be used with extreme caution.
  • Kidney Impairment: If your kidneys do not filter properly, your doctor may need to adjust your dose to prevent the medicine from building up in your body.
  • Seizure Disorders: This medicine can lower the seizure threshold, meaning it should be used cautiously if you have a history of seizures.
  • Tendonitis: If you have a history of tendon inflammation or injury, taking this medicine can increase the risk of a tendon tear.
  • Heart Rhythm Disorders (QT Prolongation): The ofloxacin component may affect the heart's electrical activity and increase the risk of abnormal heart rhythms in susceptible individuals. Use with caution if you have a history of QT prolongation, irregular heart rhythms, low potassium levels, or are taking medicines that can affect heart rhythm. 
     
Cefixime + OfloxacinMesoridazine
Critical
Cefixime + OfloxacinZiprasidone
Critical

Drug-Drug Interactions

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Cefixime + OfloxacinMesoridazine
Critical
How does the drug interact with Cefivoiz-O Tablet:
Using Mesoridazine together with Ofloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Ofloxacin is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Cefixime + OfloxacinZiprasidone
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Ziprasidone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinDisopyramide
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinDronedarone
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Dronedarone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinCisapride
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinPimozide
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Pimozide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinQuinidine
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinSotalol
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor. Do not discontinue any medications without consulting a doctor.
Cefixime + OfloxacinHalofantrine
Critical
How does the drug interact with Cefivoiz-O Tablet:
Using halofantrine together with ofloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Halofantrine together is not recommended as it can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Cefixime + OfloxacinSaquinavir
Critical
How does the drug interact with Cefivoiz-O Tablet:
Coadministration of Ofloxacin with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Cefivoiz-O Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea.
No, you should not double the dose if you forget to take Cefivoiz-O Tablet, then take it as soon as you remember or skip it if it is time for the next dose.
Yes, this medicine is prescribed for the treatment of urinary tract infection (UTI). Take Cefivoiz-O Tablet only if the doctor has prescribed you this medicine.
You should avoid driving as this medicine may cause impaired vision or affect the thinking ability so avoid such a task that needs a clear vision.
You should avoid taking Cefivoiz-O Tablet if you have peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), respiratory issues like bronchitis, sinusitis, diabetes, central nervous system disorder, or epilepsy (fits).
Yes, cefix contains cefixime as its active substance and is an antibiotic used to treat bacterial infections of urinary tract, lungs, throat, airways, tonsils, middle ear, and cervical or urethral regions.
Take Cefivoiz-O Tablet as recommended by your doctor. Taking Cefivoiz-O Tablet with milk may potentially affect its effectiveness.
No, do not take Cefivoiz-O Tablet for stomach infections as it could be due to various reasons. Also, avoid taking Cefivoiz-O Tablet for any infection without doctor’s advice.
Yes, Cefivoiz-O Tablet is a strong antibiotic that can treat various bacterial infections. Do not self-medicate.
Cefivoiz-O Tablet can be used for sinus infections (sinusitis) if caused by bacteria and if it is advised by a doctor. However, please consult a doctor as it varies for everyone based on your health condition.
No, do not take Cefivoiz-O Tablet on your own as inappropriate usage of antibiotics may cause failure of the treatment in future.
The dosage of Cefivoiz-O Tablet treatment vary based on the specific condition and patient response to the medication. If you do not notice any improvement within 3-4 days of starting the treatment, please consult your doctor. Do not self-medicate.
Cefivoiz-O Tablet contains Cefixime (cephalosporin antibiotic) and Ofloxacin (fluoroquinolone antibiotic) as its active substances.
Consult your doctor if you don’t get better after using Cefivoiz-O Tablet. Also, inform about the unwanted effects and the symptoms that worsen while using Cefivoiz-O Tablet.
Store Cefivoiz-O Tablet at room temperature. Protect from light. Keep it out of reach from children. Disposal of Cefivoiz-O Tablet is done by following the local guidelines.
No, you should never stop taking Cefivoiz-O Tablet early, even if you feel completely better. Stopping your antibiotic treatment prematurely can allow surviving bacteria to multiply and develop resistance, making future infections harder to treat. Always complete the entire course prescribed by your healthcare provider. Talk to your doctor if you have concerns.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides it is absolutely necessary. It is important to weigh the benefits against potential risks to the developing baby. Talk to your doctor before starting this medication.
You can take Cefivoiz-O Tablet with or without food. Taking it with a meal can help reduce the chances of developing a mild upset stomach or nausea. However, avoid taking it with dairy-heavy meals or calcium-rich drinks. Talk to your doctor or pharmacist for personalised advice.
Mild diarrhoea is a common side effect of antibiotics. However, if you experience severe, watery, or bloody diarrhoea accompanied by stomach cramps, stop taking the medication and seek medical help immediately, as this could be a sign of a serious bowel condition. Talk to your doctor before taking any anti-diarrhoeal medicines.
It is highly recommended to avoid alcohol while taking Cefivoiz-O Tablet. Alcohol can increase the risk of experiencing side effects such as dizziness, lightheadedness, and stomach upset, which can delay your recovery. Talk to your doctor if you have questions about alcohol use.
No, Cefivoiz-O Tablet is an antibiotic and is only effective against bacterial infections. It will not work for viral infections like colds, flu, or acute bronchitis caused by viruses. Using antibiotics unnecessarily can make them less effective for future bacterial infections. Talk to your doctor for a proper diagnosis.
Yes, the ofloxacin component belongs to a group of antibiotics called fluoroquinolones, which have been associated with an increased risk of tendonitis and tendon rupture, particularly involving the Achilles tendon. The risk is higher in older adults, people taking corticosteroids, and those with a history of tendon disorders. If you develop sudden tendon pain, swelling, or difficulty moving a joint, stop strenuous activity and contact your doctor promptly.
No, you should avoid taking antacids, iron supplements, or multivitamins containing zinc or calcium at the same time as Cefivoiz-O Tablet. These products can bind to the medicine and prevent your body from absorbing it properly. Space them at least 2 hours before or after taking your antibiotic. Talk to your doctor or pharmacist to help plan your dosing schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 202091S005,203195S006Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Cefixime Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. CiplaMed Clinical Compendium. Omnix Os Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026] Check here
  4. Ofloxacin Ofloxacin. 2002. [Accessed on 07 Feb. 2019] Check here
  5. Ofloxacin 200 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 13 October 2021] Check here
  6. Ofloxacin 200 mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 13 October 2021]Check here

Country of origin

India
Other Info - CE95115
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