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compositionComposition:CEFIXIME-200MG+CLOXACILLIN-500MG
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Prescription Medicine
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Cefolac XL 200 mg Tablet is used to treat bacterial infections. It contains Cefixime and Cloxacillin which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as indigestion, stomach pain, nausea, vomiting, diarrhoea and belching. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CEFIXIME-200MG+CLOXACILLIN-500MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cefolac XL 200 mg Tablet

Cefolac XL 200 mg Tablet is a prescription oral antibiotic combination used to treat a variety of bacterial infections, including infections of the respiratory tract, skin and soft tissues, urinary tract, and certain bone and joint infections when susceptible bacteria are involved. It combines cefixime (a third-generation cephalosporin antibiotic) and cloxacillin (a penicillinase-resistant penicillin) to provide broader coverage against selected Gram-negative bacteria and Gram-positive bacteria, including methicillin-sensitive Staphylococcus aureus (MSSA). Your doctor will prescribe this medicine only when it is appropriate for the type of infection you have.

For the best results, take Cefolac XL 200 mg Tablet exactly as prescribed at evenly spaced intervals. Because food may reduce the absorption of cloxacillin, some formulations are best taken 30–60 minutes before meals or as directed in the product information. If your specific product can be taken with food, your doctor or pharmacist will advise you accordingly. Drink plenty of water and get adequate rest to support your recovery.

Some people may experience mild side effects such as nausea, diarrhea, or indigestion while taking this medicine. These are usually temporary. However, seek medical attention immediately if you develop severe or bloody diarrhea, a widespread skin rash, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Before starting Cefolac XL 200 mg Tablet , tell your doctor if you have kidney disease, liver disease, a history of severe bowel inflammation (colitis), or allergies to penicillins or cephalosporins. Your doctor may adjust the dose if you have kidney problems. This medicine should only be used in children, older adults, or infants when prescribed by a healthcare professional, as dosing depends on age, weight, kidney function, and the type of infection.

This medicine may interact with blood thinners and medicines such as probenecid. Alcohol is not known to cause a specific harmful interaction with this combination, but it may worsen stomach upset or dehydration in some people. If you are pregnant, breastfeeding, or have other medical conditions, consult your doctor before taking this medicine.

Uses of Cefolac XL 200 mg Tablet

Cefolac XL 200 mg Tablet is used in the treatment of various bacterial infections. The detailed uses of Cefolac XL 200 mg Tablet are as follows:

  • Respiratory tract infections: Helps treat susceptible bacterial infections affecting the lungs, airways, throat, or sinuses.
  • Skin and soft tissue infections: May be prescribed for susceptible bacterial skin infections, particularly when coverage against MSSA and certain other bacteria is considered necessary by your doctor.
  • Urinary tract infections (UTIs): Helps eliminate susceptible bacteria causing painful urination, urinary frequency, and discomfort.
  • Bone and joint infections: May be used in selected bacterial bone or joint infections when the causative organisms are susceptible and your doctor considers this combination appropriate.
  • Other mixed bacterial infections: Your doctor may prescribe this medicine when broader coverage against selected Gram-positive and Gram-negative bacteria is required.

Key Benefits

  • Cefolac XL 200 mg Tablet helps eliminate susceptible bacteria, allowing your body's immune system to recover and relieving symptoms such as fever, pain, swelling, and discomfort.
  • By combining two antibiotics with different antibacterial coverage, this medicine may be useful for certain mixed or difficult bacterial infections when your doctor considers broader treatment necessary.
  • Completing the full prescribed course helps clear the infection completely and reduces the risk of recurrence and antibiotic resistance.
Side effects of Cefolac XL 200 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Cefolac XL 200 mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Cefolac XL 200 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Cefolac XL 200 mg Tablet Works

Cefolac XL 200 mg Tablet contains cefixime and cloxacillin, two antibiotics that work by interfering with bacterial cell wall formation. Cefixime prevents susceptible bacteria from building their protective cell wall. Without a strong cell wall, the bacteria break apart and die. Cloxacillin is a penicillinase-resistant penicillin. Like cefixime, it also blocks bacterial cell wall synthesis. Its structure makes it resistant to destruction by certain staphylococcal beta-lactamase (penicillinase) enzymes, allowing it to remain effective against susceptible penicillinase-producing MSSA. It is not a beta-lactamase inhibitor and does not protect cefixime. Together, these antibiotics provide broader antibacterial coverage against selected Gram-positive and Gram-negative bacteria when prescribed for appropriate infections.
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Alcohol

Caution

Cefolac XL 200 mg Tablet may interact with alcohol.

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Pregnancy

Caution

Cefolac XL 200 mg Tablet should be used in pregnant women only if the doctor thinks the clinically needed when benefits outweigh the risks.

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Breast Feeding

Caution

Cefolac XL 200 mg Tablet should be used with caution in breastfeeding mothers only if the doctor thinks the clinically needed when benefits outweigh the risks.

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Driving

Safe if prescribed

Cefolac XL 200 mg Tablet may not affect your ability to drive.

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Liver

Caution

Cefolac XL 200 mg Tablet should be used with caution in patients with liver diseases as it may affect liver function. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Cefolac XL 200 mg Tablet should be used with caution in patients with kidney diseases as it may cause nephrotoxicity (damage to the kidney). The dose may have to be adjusted by your doctor.

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Children

Caution

Please consult your doctor before using this medicine in children.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Cefolac XL 200 mg Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Cefolac XL 200 mg Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Cefolac XL 200 mg Tablet

If you suspect an overdose, or if someone has accidentally swallowed too much of this medication, seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include severe nausea, vomiting, or diarrhea.

Diet & Lifestyle Advise

  • Stay Hydrated: Drink plenty of water throughout the day to support your kidneys as they process the medication and to replace any fluids lost from mild digestive side effects.
  • Support Your Gut Health: Consider eating probiotic-rich foods like yogurt, kefir, or fermented vegetables a few hours after taking your medicine to help maintain a healthy balance of gut bacteria.
  • Rest and Recover: Give your body ample rest so your immune system can focus its energy on fighting off the bacterial infection.
  • Avoid Highly Processed Foods: Limit your intake of sugary and greasy foods, which can irritate your stomach lining and worsen mild diarrhea or nausea while on antibiotics.

Health Queries

My head is congested, and I have an allergy-related cough. I took Cefolac XL for 5 days, but my symptoms have not improved. What should I do?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Since your symptoms are related to an allergy, antibiotics like Cefolac XL (Cefixime and Cloxacillin) will not help, as they only treat bacterial infections. You should stop taking the antibiotic and consult your doctor to determine the cause. Your doctor may recommend antihistamines, decongestants, nasal corticosteroid sprays, or other allergy treatments. Simple measures such as staying hydrated, using a humidifier, avoiding allergens (dust, pollen, smoke), and saline nasal rinses may also help.
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How Soon It Starts Working

The time required for Cefolac XL 200 mg Tablet to start to work: Cefolac XL 200 mg Tablet ideally shows its action within 30 minutes after administration. The time for which the effects of Cefolac XL 200 mg Tablet last: The effect of Cefolac XL 200 mg Tablet lasts for 6 to 8 hours.

What if you forget to take Cefolac XL 200 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Cefolac XL 200 mg Tablet at room temperature, ideally below 30°C (86°F), in a cool, dry place.•Keep the medication in its original packaging or blister pack to protect it from direct sunlight and moisture. Do not store it in the bathroom cabinet.

Drug Warnings

  • Finish the Entire Course: Never stop taking this medicine early, even if your symptoms completely disappear. Stopping too soon can cause the infection to return and make the bacteria resistant to treatment.
  • Check the Packaging: Before taking your dose, inspect the tablet or capsule to ensure the packaging is intact and there is no visible damage or discoloration.
  • Do Not Share Your Medication: This antibiotic is prescribed specifically for your current infection. Never share it with others, even if they have similar symptoms.
  • Avoid Self-Medication: Do not use this medicine for viral infections like the common cold or flu, as antibiotics are completely ineffective against viruses.
  • Watch for Severe Skin Changes: Stop taking the medicine and consult a doctor immediately if you develop a progressive skin rash, blistering, or peeling.
  • Take the medicine as directed for your specific formulation, as food may reduce the absorption of the cloxacillin component.
  • Stop taking the medicine and seek immediate medical attention if you develop a severe rash, blistering, peeling skin, difficulty breathing, or swelling of the face or throat.
  • Contact your doctor if your symptoms do not begin to improve within 2–3 days, worsen during treatment, or return after completing the course.

Drug-Drug Interactions

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  • Blood thinners (such as warfarin): May increase the risk of bleeding. Your doctor may monitor you more closely.
  • Probenecid: May increase antibiotic levels in the body by slowing their elimination.
  • Other antibiotics: Some combinations may reduce antibacterial effectiveness or increase side effects. Always inform your doctor about all medicines you take.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: Food may reduce the absorption of the cloxacillin component in some formulations. Follow your product-specific instructions or your doctor's advice regarding whether to take the medicine before meals.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Cefolac XL 200 mg Tablet is used to treat bacterial infections.
Cefolac XL 200 mg Tablet is a combination of antibiotics. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis.
Cefolac XL 200 mg Tablet may be effective for sinus infection. However, it is not recommended to take any medicine without consulting your doctor to avoid unwanted effects.
People allergic to penicillin should not take Cefolac XL 200 mg Tablet as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Cefolac XL 200 mg Tablet contains cloxacillin, which has a similar structure to that of penicillin.
The common side-effects of Cefolac XL 200 mg Tablet are indigestion, stomach pain, nausea, vomiting, vaginal itching or discharge, diarrhoea and belching. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Cefolac XL 200 mg Tablet may affect liver and kidney function and blood count, so inform your doctor that you are taking Cefolac XL 200 mg Tablet before undergoing any blood tests.
Do not stop taking Cefolac XL 200 mg Tablet just because you feel better. Complete the full treatment course as prescribed by your doctor. Stopping too soon can cause the infection to return and make it harder to treat.
Some formulations containing cloxacillin are recommended to be taken 30–60 minutes before meals because food can reduce its absorption. Follow the instructions provided for your specific brand or your doctor's advice. If you are unsure, ask your pharmacist.
Mild, loose stools are a common side effect of antibiotics. However, if you experience severe, watery, or bloody diarrhea with stomach cramps, stop taking the medication and call your doctor immediately, as this can be a sign of a serious bowel condition. Talk to your doctor before taking any anti-diarrheal medicine.
You should avoid drinking alcohol while taking Cefolac XL 200 mg Tablet . Alcohol can irritate your stomach, increase the risk of dizziness, and cause dehydration, which may worsen the side effects of this medication. Talk to your doctor for further guidance.
No, Cefolac XL 200 mg Tablet is an antibiotic and is only effective against bacterial infections. It will not work for viral infections such as the common cold, flu, or acute bronchitis caused by viruses. Talk to your doctor to get an accurate diagnosis.
Current evidence suggests that most antibiotics, including cefixime and cloxacillin, are not known to significantly reduce the effectiveness of oral contraceptive pills. However, if you develop severe vomiting or diarrhea, your pill may not be absorbed properly. If you have concerns or are using hormonal contraception, speak with your doctor or pharmacist.
You should only take Cefolac XL 200 mg Tablet during pregnancy or breastfeeding if it is clearly needed and prescribed by your healthcare provider. Your doctor will weigh the benefits against any potential risks to your baby. Talk to your doctor before starting this medication.
No, you should swallow the tablet or capsule whole with a full glass of water. Crushing, chewing, or breaking the medicine can alter how it is absorbed into your body and may reduce its effectiveness. If you have difficulty swallowing pills, talk to your doctor or pharmacist about alternative liquid forms of the medication.
Treatment commonly lasts 5 to 14 days, depending on the infection being treated and how well you respond. Always complete the full course, even if you start feeling better sooner, unless your doctor advises otherwise.
If your symptoms do not improve within 2–3 days, become worse, or return after completing treatment, contact your doctor. You may need further evaluation, testing, or a different antibiotic. Do not continue or restart antibiotics without medical advice.
Yes. In some cases, pediatric formulations such as oral suspensions may be available. The dose depends on the child's age, weight, kidney function, and the type of infection. Always give this medicine only as prescribed by a healthcare professional.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - CEF0051
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