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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Cefosys Forte 250mg/125mg Injection is used to treat bacterial infections. It contains Cefotaxime and Sulbactam which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Cefosys Forte 250mg/125mg Injection

Cefosys Forte 250mg/125mg Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Cefosys Forte 250mg/125mg Injection is a combination of two medicines: Cefotaxime and Sulbactam. Cefotaxime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime).

Cefosys Forte 250mg/125mg Injection will be administered by a healthcare professional; do not self-administer. The common side effects of Cefosys Forte 250mg/125mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Cefosys Forte 250mg/125mg Injection if you are allergic to penicillin, any cephalosporin antibiotic or its contents. Before taking Cefosys Forte 250mg/125mg Injection, inform your doctor if you have kidney problems, are on a low-salt diet, have diabetes or using other antibiotics. Do not discontinue or abruptly stop using Cefosys Forte 250mg/125mg Injection as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). Cefosys Forte 250mg/125mg Injection is probably safe when used in children, pregnant women, breastfeeding mothers and elderly people. Cefosys Forte 250mg/125mg Injection may not interact with alcohol. Cefosys Forte 250mg/125mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Cefosys Forte 250mg/125mg Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Cefosys Forte 250mg/125mg Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Cefosys Forte 250mg/125mg Injection contains Cefotaxime and Sulbactam. Cefotaxime is a cephalosporin antibiotic, whereas Sulbactam is a beta-lactamase inhibitor. Cefosys Forte 250mg/125mg Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple serious bacterial infections including infections of the bloodstream (septicemia), bones (osteomyelitis), the heart valves (endocarditis), the membranes protecting the brain (meningitis) and the lining of the abdomen (peritonitis) and to prevent and treat infections following surgeries.

How Cefosys Forte 250mg/125mg Injection Works

Cefosys Forte 250mg/125mg Injection is a combination of two medicines: Cefotaxime and Sulbactam. Cefotaxime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime).

Storage

Keep Cefosys Forte 250mg/125mg Injection out of the sight and reach of children.
Side effects of Cefosys Forte 250mg/125mg Injection
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
  • Painful urination can be reduced by drinking lots of water.
  • Don't hold urine, as it can worsen the pain during urination.
  • Try taking probiotics and eating garlic, which can help reduce painful urination.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet and avoid bladder-irritating foods.
  • Quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Cefosys Forte 250mg/125mg Injection

Since Cefosys Forte 250mg/125mg Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Cefosys Forte 250mg/125mg Injection may cause false-positive results when a urine test is performed to determine glucose levels, so let your doctor know that you are taking this medicine before undergoing laboratory tests. Cefosys Forte 250mg/125mg Injection may contain sodium, so this medicine should be used with caution in people who are on a low-sodium diet. In individuals who were prescribed Cefosys Forte 250mg/125mg Injection for more than ten days, blood counts should be regularly monitored. Cefosys Forte 250mg/125mg Injection may cause a skin reaction called Steven-Johnson syndrome. So, stop taking Cefosys Forte 250mg/125mg Injection and inform your doctor immediately if you notice a rash, blistering of the skin or itching while using Cefosys Forte 250mg/125mg Injection. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Drug-Drug Interactions

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CefotaximeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefotaximeCholera, live attenuated
Severe
How does the drug interact with Cefosys Forte 250mg/125mg Injection:
Taking the cholera vaccine after or along with Cefosys Forte 250mg/125mg Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Cefosys Forte 250mg/125mg Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Cefosys Forte 250mg/125mg Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid alcoholic beverages with Cefosys Forte 250mg/125mg Injection as they can make you dehydrated and may affect your sleep.  This can make it harder for your body to aid the Cefosys Forte 250mg/125mg Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Safe if prescribed

Cefosys Forte 250mg/125mg Injection may not interact with alcohol.

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Pregnancy

Safe if prescribed

Cefosys Forte 250mg/125mg Injection is a category B medicine and may not cause harmful effects to the unborn baby. So, it is probably safe when used in pregnant women, when prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Cefosys Forte 250mg/125mg Injection is probably safe when used in breastfeeding mothers, when prescribed by a doctor.

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Driving

Caution

Cefosys Forte 250mg/125mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Cefosys Forte 250mg/125mg Injection should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Cefosys Forte 250mg/125mg Injection should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Cefosys Forte 250mg/125mg Injection is probably safe when used in children. However, the doctor may have to adjust the dose based on age, body weight and health condition.

Have a query?

FAQs

Cefosys Forte 250mg/125mg Injection is used to treat bacterial infections.

Cefosys Forte 250mg/125mg Injection contains Cefotaxime and Sulbactam. Cefotaxime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (cefotaxime).

People allergic to penicillin should not take Cefosys Forte 250mg/125mg Injection as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Cefosys Forte 250mg/125mg Injection contains cefotaxime, which has a similar structure to that of penicillin.

The common side-effects of Cefosys Forte 250mg/125mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea, and vomiting. These side-effects usually don't require medical attention. However, inform your doctor immediately if any of these side-effects persist or get worse.

In individuals who have kidney problems, have diabetes and are on a low-salt diet, Cefosys Forte 250mg/125mg Injection should be used with caution as this medicine may worsen the condition.

It is advised to let your doctor know that you are taking Cefosys Forte 250mg/125mg Injection before undergoing any laboratory tests or having a blood transfusion. Cefosys Forte 250mg/125mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Cefosys Forte 250mg/125mg Injection may cause diarrhoea in some cases. Consult the doctor if you experience diarrhoea during treatment with Cefosys Forte 250mg/125mg Injection.

Cefosys Forte 250mg/125mg Injection starts working almost immediately after administering. However, it might take a few days to notice its full effects. To treat your condition effectively complete the duration of treatment.

Consult the doctor if you do not get better or if your condition persists even after completing the duration of treatment with Cefosys Forte 250mg/125mg Injection.

The common side effects of Cefosys Forte 250mg/125mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

49, Industrial Estate, P.O. Rayon & Silk Mills, Amritsar, Punjab 143001
Other Info - CE54782

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