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compositionComposition:HEPARIN-5000IU
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Prescription Medicine
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Celhep 25000/5ml Injection

Celhep 25000/5ml Injection is an injection used to prevent and treat blood clots in your veins, arteries, or lungs. It is medically prescribed to stop harmful clots from forming or growing larger, which helps protect you from serious heart or vascular conditions.

Because this medicine is given as an injection, you must use it consistently and exactly as scheduled to keep a steady amount in your blood. Your doctor will determine how often you need to inject it, and it can be given regardless of when you eat. Making healthy changes like staying active and drinking plenty of water can also support your treatment results.

While using Celhep 25000/5ml Injection, you might notice mild bruising or soreness where you inject it. These are common, but you must contact your doctor immediately if you experience severe bleeding, unusual bruising, or dark, tarry stools.

Before starting this medicine, tell your doctor if you have high blood pressure, liver damage, or a history of bleeding disorders. Do not take this if you have active, uncontrolled bleeding or a severe drop in blood platelets from previous use of this type of medicine.

Certain medications like aspirin, as well as alcohol, can increase your risk of bleeding while using Celhep 25000/5ml Injection. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor to ensure this medicine is safe for your specific situation.

Uses of Celhep 25000/5ml Injection

Celhep 25000/5ml Injection is used to prevent and treat harmful blood clots in different medical situations. The detailed uses of Celhep 25000/5ml Injection are as follows: 

  • Deep vein thrombosis (DVT) and pulmonary embolism (PE): Celhep 25000/5ml Injection helps stop blood clots from forming in your legs or travelling to your lungs, which can be life-threatening.
  • Blood clots during medical procedures: It prevents blood from clotting during heart surgeries, blood transfusions, or kidney dialysis.
  • Arterial blood clots: It is used to treat or prevent clots in the arteries that could lead to heart attacks or other serious circulatory problems.
     

Key Benefits

Celhep 25000/5ml Injection helps prevent the formation and growth of harmful blood clots, providing important protection in situations where the risk of clotting is increased. Its rapid onset of action makes it particularly valuable when immediate anticoagulation is needed.

  • Rapid Protection Against Blood Clots: Because it begins working soon after administration, Celhep 25000/5ml Injection helps reduce the risk of dangerous clot formation during and after surgeries, hospital stays, or other high-risk medical situations.
  • Supports Healthy Blood Flow and Recovery: By preventing existing clots from getting larger and allowing the body's natural processes to break them down, Celhep 25000/5ml Injection helps maintain blood circulation and may reduce symptoms such as swelling and discomfort associated with blood clots.
Side effects of Celhep 25000Iu/5Ml Inj
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Directions for Use

This medicine is given as an injection, either under the skin (subcutaneously) or directly into a vein (intravenously). If you are injecting this medicine at home, follow these steps:

  • Wash your hands thoroughly with soap and water before handling the medicine.
  • Clean the injection site on your skin with an alcohol wipe and let it dry.
  • Gently pinch a fold of skin and insert the needle fully at the angle recommended by your doctor.
  • Inject the medicine slowly, then remove the needle and press gently with a clean cotton ball. Do not rub the site.
  • Dispose of the used needle immediately in a safe sharps container.

Always rotate your injection sites to prevent skin irritation. Be sure to follow your doctor's exact instructions on how and when to inject this medicine.

How Celhep 25000/5ml Injection Works

Celhep 25000/5ml Injection contains heparin, which works as an anticoagulant, commonly known as a blood thinner. It does not actually thin your blood, but instead blocks certain natural proteins in your body that are responsible for forming clots. By keeping these proteins inactive, the medicine prevents new clots from starting and stops existing clots from getting any bigger, allowing your body to naturally break them down over time.
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Celhep 25000/5ml Injection as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Celhep 25000/5ml Injection is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Celhep 25000/5ml Injection should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Celhep 25000/5ml Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Celhep 25000/5ml Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Celhep 25000/5ml Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Celhep 25000/5ml Injection is not recommended for children below 2 months.

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Heart

Caution

Celhep 25000/5ml Injection can be used in heart patients for the prevention of blood clots. However, caution should be exercised while receiving Celhep 25000/5ml Injection.

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Geriatrics

Caution

Geriatric patients can receive Celhep 25000/5ml Injection if prescribed by the physician. It's important to use it under close medical supervision with tailored dosing and regular monitoring.

What if I have taken an overdose of Celhep 25000/5ml Injection

The overdose of Celhep 25000/5ml Injection is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Celhep 25000/5ml Injection, please inform your doctor immediately.

Diet & Lifestyle Advise

  • Avoid injury risks: Use a soft-bristle toothbrush and an electric razor to lower your risk of bleeding from minor cuts.
  • Be cautious with activities: Skip high-impact or contact sports where you might bump your head or body, as this can cause internal bleeding.
  • Stay hydrated: Drink plenty of water unless your doctor tells you otherwise, as good hydration supports healthy circulation while you are receiving heparin treatment.
  • Keep a consistent diet: Avoid making sudden, drastic changes to your diet, especially regarding herbs and supplements, without talking to your doctor.
     

Have a query?

How Soon It Starts Working

The time required for Celhep 25000/5ml Injection to start to work: The time required for Celhep 25000/5ml Injection to start to work is immediately after IV and 20 to 60 minutes after subcutaneous administration. The time for which the effects of Celhep 25000/5ml Injection last: The duration of action for Celhep 25000/5ml Injection is unknown.

What if you forget to take Celhep 25000/5ml Injection

As Celhep 25000/5ml Injection is administered under medical supervision, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

Store Celhep 25000/5ml Injection at room temperature, between 20°C and 25°C (68°F to 77°F). Do not freeze this medicine, and keep it away from direct heat and light.

Drug Warnings

  • Inspect the Solution Before Injection: Always inspect the liquid vial before use. Do not inject the medicine if you notice particles or if the solution appears discoloured.
  • Never Reuse Needles or Syringes: Always use a new needle and syringe for each injection, as reusing them may increase the risk of serious infections.
  • Avoid Rubbing the Injection Site: Do not rub the skin after injecting Celhep 25000/5ml Injection, as this may increase the risk of bruising, irritation, or pain at the injection site.
  • Carry Medical Identification: Wear a medical alert bracelet or carry a card stating that you are using an injectable blood thinner so healthcare professionals can provide appropriate care in an emergency.
  • Inform Healthcare Providers Before Procedures: Inform all healthcare providers, including your dentist, that you are using Celhep 25000/5ml Injection before any medical procedure or surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions


Inform your doctor if you are taking any of the following medicines, as they may interact with Celhep 25000/5ml Injection: 

  • Aspirin and NSAIDs (like ibuprofen): These can greatly increase your risk of stomach bleeding and other bleeding complications when used with Celhep 25000/5ml Injection.
  • Other blood thinners: Combining this medicine with oral anticoagulants can significantly raise your risk of bleeding.


Drug-Food Interactions


Certain foods, beverages, herbs, and dietary supplements may affect how Celhep 25000/5ml Injection works or increase the risk of side effects. Examples include: 

  • Herbal supplements: Supplements like ginkgo biloba, garlic, ginger, and high doses of vitamin E can increase your risk of bleeding when taken with Celhep 25000/5ml Injection.


Drug-Disease Interactions


Inform your doctor if you have any of the following medical conditions before using Celhep 25000/5ml Injection, as additional monitoring or treatment adjustments may be required: 

  • Active bleeding: Do not use this medicine if you currently have a major bleeding medical issue, such as a bleeding ulcer.
  • Severe liver damage or kidney disease: These conditions can affect how your body processes the medicine, raising the risk of side effects.
  • Uncontrolled high blood pressure: High blood pressure can increase the risk of bleeding in the brain while using this medicine.
HeparinOritavancin
Critical

Drug-Drug Interactions

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HeparinOritavancin
Critical
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Using Celhep 25000Iu/5Ml Inj with Oritavancin can make Celhep 25000Iu/5Ml Inj less effective as a therapy.

How to manage the interaction:
Celhep 25000Iu/5Ml Inj is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Celhep 25000Iu/5Ml Inj's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Mifepristone with Celhep 25000Iu/5Ml Inj can increase the risk of negative side effects.

How to manage the interaction:
Taking Celhep 25000Iu/5Ml Inj with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Celhep 25000Iu/5Ml Inj:
When Celhep 25000Iu/5Ml Inj is taken with bazedoxifene the effects of Celhep 25000Iu/5Ml Inj are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Celhep 25000Iu/5Ml Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Tenecteplase with Celhep 25000Iu/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Celhep 25000Iu/5Ml Inj with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Alteplase with Celhep 25000Iu/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Celhep 25000Iu/5Ml Inj with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Ticlopidine with Celhep 25000Iu/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Celhep 25000Iu/5Ml Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinProtamine
Severe
How does the drug interact with Celhep 25000Iu/5Ml Inj:
When Protamine and Celhep 25000Iu/5Ml Inj are used together, can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Protamine and Celhep 25000Iu/5Ml Inj, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Tirofiban with Celhep 25000Iu/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Celhep 25000Iu/5Ml Inj and Tirofiban, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Co-administration of Celhep 25000Iu/5Ml Inj and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Celhep 25000Iu/5Ml Inj and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Celhep 25000Iu/5Ml Inj:
Taking Abciximab with Celhep 25000Iu/5Ml Inj may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Abciximab with Celhep 25000Iu/5Ml Inj can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS]

FAQs

Celhep 25000/5ml Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.

Celhep 25000/5ml Injection works by reducing the blood's ability to form harmful clots. It helps prevent existing clots from getting larger and reduces the risk of new clots forming, thereby helping to prevent complications such as deep vein thrombosis, pulmonary embolism, stroke, and heart attack.

Yes, Celhep 25000/5ml Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Celhep 25000/5ml Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Celhep 25000/5ml Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Celhep 25000/5ml Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Yes, many patients are taught how to inject Celhep 25000/5ml Injection under the skin at home. Your healthcare provider will show you exactly how to prepare and inject the medicine safely. Talk to your doctor if you have any questions about the injection process.

Mild bleeding can sometimes happen, but frequent nosebleeds or bleeding gums can be a sign that your dose needs adjustment. You should contact your healthcare provider right away to have your symptoms evaluated. Talk to your doctor.

It is best to avoid or strictly limit alcohol while using Celhep 25000/5ml Injection, as alcohol can increase your risk of stomach bleeding and affect how your blood clots. Talk to your doctor or pharmacist about safe alcohol limits.

This medicine is often preferred over other blood thinners during pregnancy because it does not cross the placenta to reach the baby. However, it must still be used under close medical supervision. Talk to your doctor to see if this is right for you.

Your doctor needs to check how quickly your blood clots to ensure you are getting the correct dose. These tests help prevent complications like bleeding or further clotting. Talk to your doctor.

No, you should avoid taking ibuprofen, aspirin, naproxen, or other NSAID pain relievers unless specifically directed by your doctor, as they can significantly increase the risk of bleeding while using Celhep 25000/5ml Injection. Acetaminophen (paracetamol) may be a safer alternative, but always consult your doctor or pharmacist before taking any additional medicines.

For minor cuts, apply firm, direct pressure with a clean cloth for at least 5 to 10 minutes. If the bleeding does not stop, or if you experience a hard blow to the head or body, seek medical help immediately. Talk to your doctor.

Long-term use of Celhep 25000/5ml Injection can sometimes cause temporary hair thinning or loss. This side effect usually stops once you finish the treatment. Talk to your doctor if this concerns you.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0298
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