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Chlorpromazine Hydrochloride 25 mg Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it is also used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm). It contains Chlorpromazine, which acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. It rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting. In some cases, you may experience certain common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CHLORPROMAZINE-25MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Chlorpromazine Hydrochloride 25 mg Tablet

Chlorpromazine Hydrochloride 25 mg Tablet is an oral prescription medication used to treat certain mental and mood disorders, such as schizophrenia and the manic phase of bipolar disorder. It is also prescribed to manage severe behavioural problems in children and to control persistent hiccups, nausea, and vomiting. This medicine works by helping to restore the balance of certain natural chemicals in the brain.

For this medication to work effectively, you must take it consistently and exactly as prescribed by your doctor. You can take `Chlorpromazine Hydrochloride 25 mg Tablet ` with or without food, though taking it with a meal or a glass of milk can help prevent stomach upset. Making simple daily adjustments, such as drinking plenty of fluids and avoiding extreme heat, can also support your treatment and improve your comfort.

While taking Chlorpromazine Hydrochloride 25 mg Tablet , you may experience mild side effects such as drowsiness, dry mouth, or dizziness when standing up. Most of these are temporary, but you should contact your doctor immediately if you notice serious symptoms like severe muscle stiffness, a high fever, or yellowing of your skin or eyes.

Do not take this if you are in a comatose state, have severe central nervous system depression, or have a history of bone marrow problems. Before starting Chlorpromazine Hydrochloride 25 mg Tablet , tell your doctor if you have liver damage, kidney disease, heart problems, glaucoma, or a history of seizures.

This medication can interact with other substances; for example, alcohol can severely increase drowsiness, and certain blood pressure medicines may cause your blood pressure to drop too low. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor to discuss whether this medication is safe for you.

Uses of Chlorpromazine Hydrochloride 25 mg Tablet

Chlorpromazine Hydrochloride 25 mg Tablet is used to manage a range of psychiatric, neurological, and physical conditions associated with abnormal brain activity, severe nausea, or persistent muscle spasms. Common uses include:

  • Schizophrenia and psychotic disorders: Chlorpromazine Hydrochloride 25 mg Tablet helps reduce hallucinations, delusions, and disorganized thinking, allowing patients to think more clearly and engage in daily activities.
  • Manic episodes in bipolar disorder: It calms overactive brain activity to control extreme excitement, rapid speech, and impulsive behaviour.
  • Severe nausea and vomiting: It acts on the brain's vomiting center to provide rapid relief from severe sickness.
  • Intractable hiccups: It relaxes the diaphragm and calms the nerves responsible for persistent, hard-to-stop hiccups.
  • Severe behavioural problems in children: It helps reduce extreme hyperactivity, aggression, and severe mood swings in children when other treatments have not worked.
     

Key Benefits

By helping control psychotic symptoms, mood disturbances, severe nausea, and persistent hiccups, Chlorpromazine Hydrochloride 25 mg Tablet offers several important benefits, including:

  • Promotes Mental and Emotional Stability: Helps reduce severe psychiatric symptoms and supports better emotional balance and daily functioning.
  • Improves Clarity of Thought: Reduces hallucinations, delusions, and disorganised thinking, making it easier to participate in everyday activities and therapy.
  • Reduces Agitation and Overactivity: Helps calm excessive excitement, impulsive behaviour, and severe restlessness.
  • Provides Relief From Severe Nausea and Vomiting: Helps control persistent sickness, reducing discomfort and the risk of dehydration.
  • Controls Persistent Hiccups: Offers relief from exhausting, long-lasting hiccups that can interfere with eating, sleeping, and daily activities.
  • Enhances Overall Quality of Life: By reducing both mental and physical symptoms, it can improve comfort, independence, and overall well-being.
     

Directions for Use

  • Chlorpromazine Hydrochloride 25 mg Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition.
  • Swallow Chlorpromazine Hydrochloride 25 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

How Chlorpromazine Hydrochloride 25 mg Tablet Works

Chlorpromazine Hydrochloride 25 mg Tablet works primarily by blocking dopamine receptors in the brain. Dopamine is a chemical messenger that transmits signals between nerve cells. In certain mental health conditions, an overactivity of dopamine in specific pathways of the brain can lead to symptoms like hallucinations, confusion, and agitation. By blocking these receptors, Chlorpromazine Hydrochloride 25 mg Tablet reduces excessive signalling, which helps calm overactive nerve pathways and restore emotional balance. Additionally, this medicine blocks other chemical receptors in the body, such as histamine and acetylcholine. This action helps control the vomiting centre in the brain and relaxes the diaphragm muscles, which effectively stops severe nausea, vomiting, and persistent hiccups.
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using Chlorpromazine Hydrochloride 25 mg Tablet .

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Pregnancy

Caution

Chlorpromazine Hydrochloride 25 mg Tablet is a category C pregnancy drug. It may affect the unborn baby. Please consult your doctor before taking Chlorpromazine Hydrochloride 25 mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Chlorpromazine Hydrochloride 25 mg Tablet is known to be passed through breast milk. So, it is recommended not to take Chlorpromazine Hydrochloride 25 mg Tablet during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if the benefits outweigh the risks.

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Driving

Unsafe

Chlorpromazine Hydrochloride 25 mg Tablet may cause drowsiness, dizziness, and light-headedness. If you are affected, do not drive or operate machinery after taking Chlorpromazine Hydrochloride 25 mg Tablet .

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Liver

Consult your doctor

Chlorpromazine Hydrochloride 25 mg Tablet should be used with caution in patients with liver diseases. Dose adjustment may be necessary.

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Kidney

Consult your doctor

Chlorpromazine Hydrochloride 25 mg Tablet should be used with caution in patients with kidney diseases. Dose adjustment may be necessary.

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Children

Caution

Chlorpromazine Hydrochloride 25 mg Tablet is not recommended for children below 1 year of age. However, please consult a doctor before giving Chlorpromazine Hydrochloride 25 mg Tablet to children.

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Heart

Consult your doctor

Please consult your doctor before using Chlorpromazine Hydrochloride 25 mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Chlorpromazine Hydrochloride 25 mg Tablet if the benefits outweigh the risks.

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Geriatrics

Caution

Chlorpromazine Hydrochloride 25 mg Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Chlorpromazine Hydrochloride 25 mg Tablet .

What if I have taken an overdose of Chlorpromazine Hydrochloride 25 mg Tablet

If you suspect an overdose, seek emergency medical attention or call a poison control center immediately. Symptoms of an overdose may include severe drowsiness, low blood pressure, rapid heart rate, muscle tremors, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to prevent dry mouth and help manage constipation, which are common side effects of this medication.
  • Rise slowly: To prevent dizziness and fainting caused by a sudden drop in blood pressure, take your time when moving from a lying or sitting position to a standing position.
  • Protect your skin: This medication can make your skin highly sensitive to sunlight. Wear protective clothing, a wide-brimmed hat, and high-SPF sunscreen when spending time outdoors, and avoid tanning beds.
  • Avoid extreme heat: Chlorpromazine Hydrochloride 25 mg Tablet can make it harder for your body to cool down. Avoid saunas, hot tubs, and intense exercise in hot weather to prevent heat stroke.
     
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How Soon It Starts Working

The time required for Chlorpromazine Hydrochloride 25 mg Tablet to start to work: The time required for Chlorpromazine Hydrochloride 25 mg Tablet to start to work is 30 to 60 minutes after administration. The time for which the effects of Chlorpromazine Hydrochloride 25 mg Tablet last: The effect of Chlorpromazine Hydrochloride 25 mg Tablet lasts for 4 to 6 hours.

What if you forget to take Chlorpromazine Hydrochloride 25 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Chlorpromazine Hydrochloride 25 mg Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container with the lid tightly closed to protect it from light and moisture.

Drug Warnings

  • Avoid alcohol: Do not consume alcohol while taking Chlorpromazine Hydrochloride 25 mg Tablet , as it can dangerously increase drowsiness, dizziness, and the risk of breathing difficulties.
  • Do not stop suddenly: Always consult your doctor before stopping this medication. Stopping abruptly can cause physical withdrawal symptoms like nausea, vomiting, and shakiness.
  • Be cautious with tools and machinery: This medicine can cause severe drowsiness and slow your reflexes. Do not drive or operate machinery until you know how this medication affects you.
  • Monitor for muscle changes: Pay close attention to any unusual, uncontrolled movements of your tongue, mouth, face, or limbs, and report them to your doctor immediately.
  • Keep regular doctor appointments: Your doctor may need to perform regular blood tests, liver function tests, and eye exams to monitor your health while you are on this medication.
     

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Drug-Drug Interactions

Chlorpromazine Hydrochloride 25 mg Tablet can interact with medicines that affect alertness, blood pressure, or anticholinergic activity, potentially increasing the risk of side effects, including:

  • Central Nervous System Depressants: Sleep aids, opioid pain relievers, muscle relaxants, and anti-anxiety medicines may cause excessive drowsiness, sedation, or breathing difficulties when taken with Chlorpromazine Hydrochloride 25 mg Tablet .
  • Blood Pressure Medications: Combining these medicines may increase the risk of severe dizziness, light-headedness, and fainting due to excessive lowering of blood pressure.
  • Anticholinergic Medicines: These medications can worsen side effects such as dry mouth, constipation, blurred vision, and difficulty urinating.

Drug-Food Interactions

Certain beverages may affect the way Chlorpromazine Hydrochloride 25 mg Tablet works or increase the likelihood of treatment-related side effects, including:

  • Alcohol: Avoid drinking alcohol, as it can significantly increase drowsiness, sedation, and impaired coordination.
  • Caffeine: Large amounts of coffee, tea, energy drinks, or caffeinated soft drinks may interfere with the calming effects of this medication.

Drug-Disease Interactions

Chlorpromazine Hydrochloride 25 mg Tablet may not be suitable for people with certain neurological, cardiovascular, liver, blood, eye, or respiratory conditions, including:

  • Severe Liver Damage: This medicine should not be used in patients with significant liver impairment due to an increased risk of serious side effects.
  • Bone Marrow Depression: Avoid use if you have reduced bone marrow function or low blood cell production.
  • Comatose States: This medication should not be used in patients who are unconscious or in a coma.
  • Parkinson's Disease: Chlorpromazine Hydrochloride 25 mg Tablet may worsen movement-related symptoms associated with this condition.
  • Heart Disease: Use with caution, as it may affect heart rhythm and blood pressure.
  • Glaucoma: This medicine may worsen symptoms of certain types of glaucoma.
  • Respiratory Disorders: Use carefully in people with breathing problems, as it may increase respiratory depression.
  • History of Seizures: Chlorpromazine Hydrochloride 25 mg Tablet may lower the seizure threshold and increase the risk of seizures in susceptible individuals.
     

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Chlorpromazine Hydrochloride 25 mg Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it may also be used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm).
Chlorpromazine Hydrochloride 25 mg Tablet works by blocking dopamine receptors in the brain. By inhibiting the synthesis of the dopamine hormone, there will be a decrease in the occurrence of symptoms in patients with schizophrenia and bipolar depression.
You are not recommended to stop taking Chlorpromazine Hydrochloride 25 mg Tablet without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or an extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take Chlorpromazine Hydrochloride 25 mg Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Chlorpromazine Hydrochloride 25 mg Tablet , please consult your doctor so that the dose can be gradually reduced.
Chlorpromazine Hydrochloride 25 mg Tablet is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking Chlorpromazine Hydrochloride 25 mg Tablet .
Long-term use of Chlorpromazine Hydrochloride 25 mg Tablet may cause dyskinesia (a movement disorder) in some cases. However, your doctor will prescribe this medication if the benefits outweigh the risks.
Chlorpromazine Hydrochloride 25 mg Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Chlorpromazine Hydrochloride 25 mg Tablet .
No, Chlorpromazine Hydrochloride 25 mg Tablet is not a benzodiazepine or a sleeping tablet. It belongs to the class of medications called antipsychotics. However, consult your doctor if you have any concerns.
No, Chlorpromazine Hydrochloride 25 mg Tablet is not a controlled substance/ narcotic. However, a doctor's prescription is required to purchase it.
No, Chlorpromazine Hydrochloride 25 mg Tablet does not have a high potential for addiction. However, take Chlorpromazine Hydrochloride 25 mg Tablet as prescribed by your doctor.
You are recommended to take the advice of your doctor because it is not the primary treatment for opiate withdrawal.
The common side effects of Chlorpromazine Hydrochloride 25 mg Tablet are sleepiness, orthostatic hypotension (low blood pressure), dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremors. Most of these side effects of Chlorpromazine Hydrochloride 25 mg Tablet do not require medical attention and typically resolve on their own over time. However, if these side effects persist longer, please consult your doctor.
No, you should avoid alcohol while taking Chlorpromazine Hydrochloride 25 mg Tablet . Alcohol can dangerously increase drowsiness, dizziness, and the risk of severe respiratory depression. Talk to your doctor if you have concerns about alcohol use.
Yes, weight gain is a recognized side effect of Chlorpromazine Hydrochloride 25 mg Tablet . Managing your diet and staying physically active can help, but you should discuss any significant weight changes with your doctor.
Yes, this medication can make your skin much more sensitive to sunlight, increasing your risk of severe sunburn. Wear protective clothing and high-SPF sunscreen when outdoors. Talk to your doctor if you develop a severe skin reaction.
Taking Chlorpromazine Hydrochloride 25 mg Tablet during the third trimester of pregnancy may cause withdrawal symptoms or breathing problems in the newborn. Talk to your doctor to weigh the risks and benefits of using this medication during pregnancy.
This medicine can cause a temporary drop in blood pressure when you change positions. To prevent this, rise slowly from a sitting or lying position. Talk to your doctor if the dizziness is severe or causes fainting.
If you develop a sudden fever, especially when accompanied by muscle stiffness and a rapid heartbeat, seek emergency medical care immediately. This can be a sign of a rare but life-threatening reaction. Talk to your doctor right away.

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Country of origin

India

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, Riico, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - CHL0130
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